Stimuli-responsive self-assembly of cellulose nanocrystals (CNCs): Structures, functions, and biomedical applications.

Abstract:

:Cellulose nanocrystals (CNCs) have received a significant amount of attention from the researchers. It is used as a nanomaterial for various applications due to its excellent physiochemical properties for the last few decades. Self-assembly is a phenomenon where autonomous reorganization of randomly oriented species occurs elegantly. Self-assembly is responsible for the formation of the hierarchical cholesteric structure of CNCs. This process is highly influenced by several factors, such as the surface chemistry of the nanoparticles, intermolecular forces, and the fundamental laws of thermodynamics. Various conventional experimental designs and molecular dynamics (MD) studies have been applied to determine the possible mechanism of self-assembly in CNCs. Different external factors, like pH, temperature, magnetic/electric fields, vacuum, also influence the self-assembly process in CNCs. Notably, better responses have been observed in CNCs-grafted polymer nanocomposites. These functionalized CNCs with stimuli-responsive self-assembly have immense practical applications in modern biotechnology and medicine. Herein, we have concisely discussed the mechanism of the self-assembled CNCs in the presence of different external factors such as pH, temperature, electric/magnetic fields, and their biomedical applications.

journal_name

Int J Biol Macromol

authors

Ganguly K,Patel DK,Dutta SD,Shin WC,Lim KT

doi

10.1016/j.ijbiomac.2020.03.171

subject

Has Abstract

pub_date

2020-07-15 00:00:00

pages

456-469

eissn

0141-8130

issn

1879-0003

pii

S0141-8130(20)32750-1

journal_volume

155

pub_type

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