Abstract:
:Concomitance of four fragile sites (at 16p13, 16q22, 16q23, Yq12) in the lymphocyte cultures of two brothers is reported. The expression of each of these fragile sites was enhanced (or induced) by different culture conditions. Some of the inducing conditions are already known and others are reported here for the first time. The meaning of the fragile sites is discussed and a possible viral etiology suggested. Concomitance of some of them may be a potential causal factor for deletions, translocations, or inversions.
journal_name
Hum Genetjournal_title
Human geneticsauthors
Shabtai F,Orlin J,Hart J,Halbrecht I,Klar D,Friedman Jdoi
10.1007/BF00278791subject
Has Abstractpub_date
1986-09-01 00:00:00pages
85-9issue
1eissn
0340-6717issn
1432-1203journal_volume
74pub_type
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