Management of drug-resistant tuberculosis in special sub-populations including those with HIV co-infection, pregnancy, diabetes, organ-specific dysfunction, and in the critically ill.

abstract：Background:Calcific aortic valve disease (CAVD) is the most common type of valvular heart disease in the elderly. This study is aimed to explore molecular mechanism of CAVD via bioinformatics analysis. Methods:The gene expression profiles of GSE51472 (including 5 normal aortic valve and 5 calcified aortic valve) and G...

journal_title：Journal of thoracic disease

authors： Zhang Y,Ma L

更新日期：2019-12-01 00:00:00

abstract：Background:To evaluate therapeutic efficacy of minimally invasive and small incision surgery [minimally invasive surgery (MIS)] in patients with non-flail chest rib fractures through a prospective cohort study. Methods:This study included 98 patients with non-flail chest rib fractures (≥3 displaced fractures) and 66 p...

journal_title：Journal of thoracic disease

authors： Li Y,Gao E,Yang Y,Gao Z,He W,Zhao Y,Wu W,Zhao T,Guo X

更新日期：2020-07-01 00:00:00

abstract：:Transcatheter aortic valve implantation is an important therapeutic option for patients with symptomatic, severe aortic stenosis at increased risk for open surgical aortic valve replacement. Although a number of alternative vascular access sites have been developed, transfemoral access is overwhelmingly the dominant a...

journal_title：Journal of thoracic disease

authors： Vora AN,Rao SV

更新日期：2018-11-01 00:00:00

abstract：:Advances in the treatment of non-small cell lung cancer (NSCLC) over the last decade have predominantly involved the development of therapies directed at molecular targets such as mutations in the epidermal growth factor receptor (EGFR) or rearrangements in the anaplastic lymphoma kinase (ALK) gene. Other targets have...

journal_title：Journal of thoracic disease

authors： Savas P,Hughes B,Solomon B

更新日期：2013-10-01 00:00:00

abstract：:Analyses of cell-free tumor DNA (ctDNA) have provided a non-invasive strategy for cancer diagnosis, the identification of molecular aberrations for treatment identification, and evaluation of tumor response. Sensitive and specific ctDNA sequencing strategies have allowed for implementation into clinical practice for t...

journal_title：Journal of thoracic disease

authors： Bulbul A,Leal A,Husain H

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Transbronchial biopsy (TBB) using radial endobronchial ultrasound with a guide sheath (REBUS-GS) has improved the diagnosis of peripheral pulmonary lesions (PPLs). Because of the high cost of the GS, REBUS with distance (REBUS-D) has certain advantages. The aim of this study was to compare the diagnostic yie...

journal_title：Journal of thoracic disease

authors： Zhang SJ,Zhang M,Zhou J,Zhang QD,Xu QQ,Xu X

更新日期：2016-11-01 00:00:00

abstract：:While ionizing radiotherapy (RT) can provide durable local control, the relative radiosensitivity of surrounding organs such as the lungs and heart and the distributed nature of the pleura limit the ability to safely deliver RT for patients with malignant pleural mesothelioma (MPM). Recent advances in the technologica...

journal_title：Journal of thoracic disease

authors： Cramer G,Simone CB 2nd,Busch TM,Cengel KA

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Previously, most studies did not discuss about the characteristics of lung-involved toxocariasis without eosinophilia. However, the patients are not always accompanied by eosinophilia, so it is necessary to learn about the clinical and radiologic features that may predict pulmonary toxocariasis without eosin...

journal_title：Journal of thoracic disease

authors： Park BM,Jeong SO,Park HS,Jung SS,Kim SY,Kim JO,Lee JE

更新日期：2014-12-01 00:00:00

abstract：:Every patient undergoing curative treatment for primary lung cancer is a candidate for metachronous lung cancer, with a reported risk of 5% per year. The majority of cases are stage I patients. Patients who undergo resection for lung cancer should be followed regularly. A metachronous lung cancer that develops as bila...

journal_title：Journal of thoracic disease

authors： Kocaturk CI,Cansever L,Kanmaz DZ,Bedirhan MA

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:To report a rare case of atypical histiocytic tumor of the lung with a review of literature. METHODS:The clinical materials were noted. Literature related to this condition from the past 50 years was reviewed from the group of histiocytic tumors. RESULTS AND CONCLUSIONS:Clinical manifestations were non-spec...

journal_title：Journal of thoracic disease

authors： Li H,Cao W,Li H,Zhang R,Zhou Y,Xu J,Garfield DH

更新日期：2013-08-01 00:00:00

abstract：Background:Uniportal video-assisted thoracoscopic (U-VATS) lobectomy has been becoming the technique of choice in an increasing number of centers. The aim of our study was to review our experience, evaluating the learning curve of U-VATS for lung lobectomy and outcomes. Methods:The prospectively collected clinical dat...

journal_title：Journal of thoracic disease

authors： Nachira D,Meacci E,Porziella V,Vita ML,Congedo MT,Chiappetta M,Petracca Ciavarella L,Ismail M,Gualtieri E,Cesario A,Margaritora S

更新日期：2018-11-01 00:00:00

abstract：:Transcatheter procedures offer less invasive approaches allowing rapid recovery and earlier hospital discharge. A number of international guidelines have defined the role of echocardiography spanning diagnosis, detailed anatomical assessment, device sizing and selection, peri-procedure guidance and post device surveil...

journal_title：Journal of thoracic disease

authors： Rana BS

更新日期：2018-09-01 00:00:00

abstract：:Approximately 6% of women with breast cancer are diagnosed before the age of 40. Young age is an independent predictor of adverse outcome and most young breast cancer patients receive systemic treatment with chemotherapy, hormonal therapy or both. The loss or impairment of fertility is a potential side effect of antin...

journal_title：Journal of thoracic disease

authors： Lambertini M,Anserini P,Levaggi A,Poggio F,Del Mastro L

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Beta-2 adrenergic receptor (β2AR) downregulation is critical to asthma rescue therapy; however, tolerance, also known as β2AR or bronchodilator desensitization, mechanisms potentially resulting in life-threatening rescue treatment failure remain poorly understood. METHODS:Airway smooth muscle cells (ASMCs) ...

journal_title：Journal of thoracic disease

authors： Ni S,Zhang Y,Wang H,Zhou J,Ding L,Liu H

更新日期：2013-10-01 00:00:00

abstract：:Aortic dissection can present in a variety of ways and one of the most documented risk factors includes systemic hypertension. Occasionally aortic dissection can be diagnosed late due to an insidious presentation. Fever has been described in people with aortic dissection but rarely as the main presenting feature. We p...

journal_title：Journal of thoracic disease

authors： Patris V,Whiteley J,Argiriou O,Lama N,Georgiou H,Constantinou C,Argiriou M,Charitos C

更新日期：2014-12-01 00:00:00

abstract：Background:The purpose of this study is to report the efficacy of the mono antiplatelet plus anticoagulation therapy for prevention of reocclusion in patients with atrial fibrillation (AF) undergoing endovascular treatment for lower extremity ischemia. Methods:From March 2014 to July 2016, 32 (21 males; range, 68-84 y...

journal_title：Journal of thoracic disease

authors： Yuan L,Chen C,Li Z,Zhu G,Bao J,Zhao Z,Lu Q,Jing Z

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Concurrent chemoradiotherapy (CRT) with 5-fluorouracil (5-FU) and cisplatin (CDDP) are often associated with significant incidence of toxic effects in elderly patients with esophageal cancer. This phase I trial was designed to determine the maximum tolerated dose (MTD) and dose-limiting toxicity (DLT) of S-1...

journal_title：Journal of thoracic disease

authors： Ji Y,Qiu G,Sheng L,Sun X,Zheng Y,Chen M,Du X

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Ground glass opacity (GGO) generally associated with the lepidic component of lung adenocarcinoma. However, in some cases, GGO nodules have been associated with invasive adenocarcinomas, where a lepidic component is minimal or absent. The purpose of this study is to evaluate the clinicopathological character...

journal_title：Journal of thoracic disease

authors： Moon Y,Sung SW,Lee KY,Park JK

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Postoperative cardiopulmonary complications might be fatal for patients with lung cancer after surgery. The aim of this study was to identify the risk factors of postoperative cardiopulmonary complications in lung cancer patients and get a fitting formula for predicting incidences of cardiopulmonary complica...

journal_title：Journal of thoracic disease

authors： Li Y,Ma YL,Gao YY,Wang DD,Chen Q

更新日期：2017-06-01 00:00:00

abstract：AIM:The aim of this retrospective observational study was to investigate the effect of on-pump versus off-pump coronary artery bypass grafting (CABG) for patients with coronary artery diseases (CAD). METHODS:A retrospective observational study was performed using a propensity score analysis in 290 consecutive patients...

journal_title：Journal of thoracic disease

authors： Liu P,Wang F,Ren S,Lin F,Yang Y,Fan X,Sun G,Zheng X,Liu J,Yuan J,Ye Z

更新日期：2014-06-01 00:00:00

abstract：Background:The incidence of conduction disturbances requiring permanent pacemaker (PPM) implantation following transcatheter aortic valve replacement (TAVR) have remained a common concern. The purpose of this study was to evaluate the impact of postprocedural PPM implantation following TAVR on clinical outcomes. Metho...

journal_title：Journal of thoracic disease

authors： Xi Z,Liu T,Liang J,Zhou YJ,Liu W

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Cyclooxygenase-2 (COX-2) has been implicated in tumorigenesis and metastasis, and it presumably mediates the proliferation of endothelial cells and promotes vascular permeability. However, the prognostic value of COX-2 overexpression in patients with non-small cell lung cancer (NSCLC) remains controversial. ...

journal_title：Journal of thoracic disease

authors： Zhan P,Qian Q,Yu LK

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:The use of uniportal video-assisted thoracoscopic surgery (VATS) has been increasing worldwide. Our main goal was to describe the evolution of uniportal surgery in the biggest private hospital in Latin America that is located in São Paulo, Brazil. METHODS:This descriptive and retrospective study included pa...

journal_title：Journal of thoracic disease

authors： de Oliveira A,Couto TAPP

更新日期：2017-04-01 00:00:00

abstract：Background:To investigate the capability of radiomic analysis using T2-weighted (T2W) and spectral attenuated inversion-recovery T2-weighted (SPAIR T2W) magnetic resonance imaging (MRI) for predicting the therapeutic response of esophageal squamous cell carcinoma (ESCC) to chemoradiotherapy (CRT). Methods:Pretreatment...

journal_title：Journal of thoracic disease

authors： Hou Z,Li S,Ren W,Liu J,Yan J,Wan S

更新日期：2018-04-01 00:00:00

abstract：Background:To investigate the roles of gastrin-releasing peptide (ProGRP) in the diagnosis of small cell lung cancer (SCLC). Methods:We retrospectively analyzed data from 11,206 patients with clinical suspicion of lung cancer from January 1, 2015 to May 31, 2018. ProGRP and neuron-specific enolase (NSE) were detected ...

journal_title：Journal of thoracic disease

authors： Dong A,Zhang J,Chen X,Ren X,Zhang X

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Red cell distribution width (RDW) might be a novel biomarker that reflects multiple physiological impairments related to atherosclerosis and coronary artery diseases (CAD). We conducted this systematic review and meta-analysis to evaluate the association of RDW between all-cause mortality and fatal/non-fatal...

journal_title：Journal of thoracic disease

authors： Su C,Liao LZ,Song Y,Xu ZW,Mei WY

更新日期：2014-10-01 00:00:00

abstract：Background:The development of minimally invasive surgical approaches has revolutionized surgical care and greatly improved surgical outcomes. This study aimed to evaluate the clinical effectiveness of a powered vascular stapler (PVS) during video-assisted thoracoscopic surgery (VATS) lobectomy. Methods:This prospectiv...

journal_title：Journal of thoracic disease

authors： Qiu B,Kang X,Chen KN,Hu J,Li J,Zeng L,Fegelman EJ,Schwiers ML,Creedon EE,Waggoner JR,Ding D,Yang T,Gao S

更新日期：2019-05-01 00:00:00

abstract：:Patients with locally advanced esophageal cancer are treated with definitive chemoradiation (dCXRT) for a number of reasons. Some patients are never referred to a surgeon for a con-versation about surgery, others decline surgery, and some are not candidates for surgery due to a sag in performance status secondary to t...

journal_title：Journal of thoracic disease

authors： Hofstetter WL

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:The rate of detection of small pulmonary nodules (SPNs) has increased. Thoracoscopic resection following image-guided localization had been a reliable alternative in their treatment. We present our experience with image-guided dye localization using robotic C-arm computed tomography (CT) followed by immediat...

journal_title：Journal of thoracic disease

authors： Yang SM,Ko WC,Lin MW,Hsu HH,Chan CY,Wu IH,Chang YC,Chen JS

更新日期：2016-10-01 00:00:00

abstract：Background:CO2 insufflation could provide a better surgical field during single-incision thoracoscopic surgery (SITS) with small tidal two-lung ventilation (ST-TLV). Here we compared the surgical field and physiological effects of ST-TLV with and without CO2 during SITS. Methods:Patients underwent scheduled SITS bulle...

journal_title：Journal of thoracic disease

authors： Lee DK,Kim H,Kim HK,Chung DI,Han KN,Choi YH

更新日期：2018-08-01 00:00:00