Targeted therapy in lung cancer: IPASS and beyond, keeping abreast of the explosion of targeted therapies for lung cancer.

abstract：Background:There has been controversy regarding prognostic factors for surgically resected primary pulmonary sarcomatoid carcinoma (PSC). Recently, several studies have shown that neutrophil-to-lymphocyte ratio (NLR) was a prognostic factor for various types of cancers from multiple organs. Therefore, we performed this...

journal_title：Journal of thoracic disease

authors： Seong YW,Han SJ,Jung W,Jeon JH,Cho S,Jheon S,Kim K

更新日期：2019-03-01 00:00:00

abstract：:The incidence of pulmonary nodules and lung cancer is rising. Some of this increase in incidence is due to improved pick up by newer imaging modalities. However, the goal is to diagnose these lesion, many of which are located in the periphery, by safe and relatively non-invasive methods. This has led to the emergence ...

journal_title：Journal of thoracic disease

authors： Goud A,Dahagam C,Breen DP,Sarkar S

更新日期：2016-07-01 00:00:00

abstract：:Peripheral lung nodule evaluation represents a clinical challenge. Given that many nodules will be incidentally found with lung cancer screening following the publication of the National Lung Screening Trial (NLST), the goal is to find an accurate, safe and minimally-invasive diagnostic modality to biopsy the concerni...

journal_title：Journal of thoracic disease

authors： Arias S,Yarmus L,Argento AC

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Although N-ERC/mesothelin (N-ERC) is an attractive diagnostic and treatment monitoring biomarker for malignant pleural mesothelioma (MPM), its clinical utility for predicting the prognosis has not yet been clarified. The aim of this study is to investigate whether the serum N-ERC level can accurately predict...

journal_title：Journal of thoracic disease

authors： Mori T,Tajima K,Hirama M,Sato T,Kido K,Iwakami S,Sasaki S,Iwase A,Shiomi K,Maeda M,Hino O,Takahashi K

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVE:To study the clinical characteristics, treatment and prognosis of patients with solitary fibrous tumor of the pleura (SFTP) in order to improve the diagnostic accuracy and treatment of SFTP. METHODS:A retrospective analysis of clinical and imaging features, serum biochemical changes, pathological characteris...

journal_title：Journal of thoracic disease

authors： Chu X,Zhang L,Xue Z,Ren Z,Sun YE,Wang M,Liu M

更新日期：2012-04-01 00:00:00

abstract：:The concept of enhanced recovery after surgery (ERAS), initially introduced in the field of colorectal surgery, has been developed in order to optimize the postoperative course. In recent years the number of authors analyzing the role of ERAS in lung cancer surgery is increasing, highlighting several interventions wit...

journal_title：Journal of thoracic disease

authors： Comacchio GM,Monaci N,Verderi E,Schiavon M,Rea F

更新日期：2019-03-01 00:00:00

abstract：Background:The aim of this study was to evaluate the hemodynamic effect of different suturing techniques for aortic valve replacement (AVR) in vitro. Whether or not the applied suturing technique impacts the outflow tract diameter by narrowing the annulus diameter was examined. Methods:The commonly applied non-evertin...

journal_title：Journal of thoracic disease

authors： Puluca N,Münsterer A,Prinzing A,Sexton ZA,Lange R,Meyer-Saraei R,Scharfschwerdt M

更新日期：2020-05-01 00:00:00

abstract：:Lung transplantation (LTx) is routinely performed with sacrifice of the bronchial arterial circulation. We review bronchial artery anatomy and surgical technique for LTx with direct bronchial arterial revascularization (BAR). We also update the published clinical experience, including from our center, of LTx with BAR....

journal_title：Journal of thoracic disease

authors： Yun JJ,Unai S,Pettersson G

更新日期：2019-09-01 00:00:00

abstract：:Tuberculosis remains a major problem globally, and is the leading cause of death from an infectious agent. Drug-resistant tuberculosis threatens to marginalise the substantial gains that have recently been made in the fight against tuberculosis. Drug-resistant TB has significant associated morbidity and a high mortali...

journal_title：Journal of thoracic disease

authors： Esmail A,Sabur NF,Okpechi I,Dheda K

更新日期：2018-05-01 00:00:00

abstract：Background:Thoracoscopic surgery (TS) has been used more commonly as a less invasive procedure for early-stage non-small cell lung cancer (NSCLC) than conventional thoracotomy (TH) in Japan. However, limited evidential data are available to compare the treatment efficacy of TS and TH. The purpose of this study was to r...

journal_title：Journal of thoracic disease

authors： Nakao M,Ichinose J,Matsuura Y,Nakagawa K,Okumura S,Mun M

更新日期：2019-07-01 00:00:00

abstract：:We reported the case of a 70-year-old man who was admitted to neurologic wards for recurrent syncope for 3 years. Unfortunately, just 2 hours after his admission, he suddenly collapsed and failed to return of spontaneous circulation (ROSC) after a 100-minute standard cardiopulmonary resuscitation (CPR). Fortunately, h...

journal_title：Journal of thoracic disease

authors： Wu JP,Gu DY,Wang S,Zhang ZJ,Zhou JC,Zhang RF

更新日期：2014-12-01 00:00:00

abstract：:Every patient undergoing curative treatment for primary lung cancer is a candidate for metachronous lung cancer, with a reported risk of 5% per year. The majority of cases are stage I patients. Patients who undergo resection for lung cancer should be followed regularly. A metachronous lung cancer that develops as bila...

journal_title：Journal of thoracic disease

authors： Kocaturk CI,Cansever L,Kanmaz DZ,Bedirhan MA

更新日期：2013-06-01 00:00:00

abstract：Background:Bivalirudin has been shown to be associated with less major bleeding than heparin in patients undergoing percutaneous coronary intervention (PCI); but the confounding effect of concomitant glycoprotein IIb/IIIa inhibitors (GPI) limits meaningful comparison. We performed a systematic review and meta-analysis ...

journal_title：Journal of thoracic disease

authors： Anantha-Narayanan M,Anugula D,Gujjula NR,Reddy YNV,Baskaran J,Kaushik M,Alla VM,Raveendran G

更新日期：2018-06-01 00:00:00

abstract：Background:Eosinophilic chronic obstructive pulmonary disease (COPD) patients have eosinophilic airway inflammation. No prospective study has reported blood eosinophil counts in an endemic area for parasitic infection. The primary objective was to compare exacerbation rates. The secondary objectives were patient-report...

journal_title：Journal of thoracic disease

authors： Juthong S,Kaenmuang P

更新日期：2020-09-01 00:00:00

abstract：Background:Endoscopic thoracic sympathectomy (ETS) has not been widely adopted for treating craniofacial hyperhidrosis (CFH) due to its known postoperative complication, compensatory hyperhidrosis (CH). In this study, we evaluated whether the autonomic nerve analysis data via pre-ETS heart rate variability (HRV) test c...

journal_title：Journal of thoracic disease

authors： Moon DH,Kang DY,Lee HS,Lee JW,Lee YJ,Lee S

更新日期：2020-05-01 00:00:00

abstract：:Non-specific presentation and normal examination findings in early disease often result in tracheal obstruction being overlooked as a diagnosis until patients present acutely. Once diagnosed, surgical options should be considered, but often patient co-morbidity necessitates other interventional options. Non-resectable...

journal_title：Journal of thoracic disease

authors： Bacon JL,Patterson CM,Madden BP

更新日期：2014-03-01 00:00:00

abstract：:Obstructive sleep apnea (OSA) is probably the most common respiratory disorder, with recent data from the United States and Europe suggesting that between 14% and 49% of middle-aged men have clinically significant OSA. The intimate relationship between OSA and obesity means that its prevalence will only increase as th...

journal_title：Journal of thoracic disease

authors： Garvey JF,Pengo MF,Drakatos P,Kent BD

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVE:Epidermal growth factor receptor (EGFR) mutation mostly occurred in lung adenocarcinoma, rarely in squamous cell carcinoma (SQCC). EGFR mutation rate in SQCC varied in previous reports, and the efficacy of EGFR tyrosine kinase inhibitors (TKIs) in SQCC harboring EGFR mutation has not yet been fully evaluated....

journal_title：Journal of thoracic disease

authors： Fang W,Zhang J,Liang W,Huang Y,Yan Y,Wu X,Hu Z,Ma Y,Zhao H,Zhao Y,Yang Y,Xue C,Zhang J,Zhang L

更新日期：2013-10-01 00:00:00

abstract：Background:Endobronchial stents that are used to treat airway obstruction may migrate over time. These stents can be repositioned. However, not much has been reported about this technique. We retrospectively reviewed our experience with self-expanding metallic stents (SEMS) and attempted to determine-(I) factors relate...

journal_title：Journal of thoracic disease

authors： Biswas A,Jantz MA,Fernandez-Bussy S,Flanagan M,Mehta HJ

更新日期：2020-05-01 00:00:00

abstract：Background:The purpose of this study is to report the efficacy of the mono antiplatelet plus anticoagulation therapy for prevention of reocclusion in patients with atrial fibrillation (AF) undergoing endovascular treatment for lower extremity ischemia. Methods:From March 2014 to July 2016, 32 (21 males; range, 68-84 y...

journal_title：Journal of thoracic disease

authors： Yuan L,Chen C,Li Z,Zhu G,Bao J,Zhao Z,Lu Q,Jing Z

更新日期：2018-03-01 00:00:00

abstract：:Flexible bronchoscopes are being continuously improved, and an ultrathin bronchoscope with a working channel that allows the use of a radial-type endobronchial ultrasound (EBUS) probe is now available. The ultrathin bronchoscope has good maneuverability for passing through the small bronchi and good accessibility to p...

journal_title：Journal of thoracic disease

authors： Oki M,Saka H

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVE:To report a rare case of atypical histiocytic tumor of the lung with a review of literature. METHODS:The clinical materials were noted. Literature related to this condition from the past 50 years was reviewed from the group of histiocytic tumors. RESULTS AND CONCLUSIONS:Clinical manifestations were non-spec...

journal_title：Journal of thoracic disease

authors： Li H,Cao W,Li H,Zhang R,Zhou Y,Xu J,Garfield DH

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:The precise head to head relationships between Cardio-pulmonary exercise testing (CPET) parameters and patients' daily symptoms/activities and the disease social/emotional impact are less well defined. In this study, the correlation of COPD daily symptoms and quality of life [assessed by St. George's Respira...

journal_title：Journal of thoracic disease

authors： Mirdamadi M,Rahimi B,Safavi E,Abtahi H,Peiman S

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:The use of uniportal video-assisted thoracoscopic surgery (VATS) has been increasing worldwide. Our main goal was to describe the evolution of uniportal surgery in the biggest private hospital in Latin America that is located in São Paulo, Brazil. METHODS:This descriptive and retrospective study included pa...

journal_title：Journal of thoracic disease

authors： de Oliveira A,Couto TAPP

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:Recurrence of pectus excavatum (PE) is not an uncommon problem after open repair using the Ravitch technique. The optimal approach for redo surgery is still under debate, especially in adults with less chest wall pliability. Aim of this study was to investigate the usefulness and efficacy of the minimally in...

journal_title：Journal of thoracic disease

authors： Kocher GJ,Gstrein N,Jaroszewski DE,Ewais MM,Schmid RA

更新日期：2016-08-01 00:00:00

abstract：:Natural history of acute Stanford type A aortic dissection (AAAD) implies the need of emergent surgical treatment in the vast majority of cases. Nevertheless, conservative treatment has been described to yield acceptable outcomes, when compared to surgery, in selected high risk cases of thrombosed false lumen. We repo...

journal_title：Journal of thoracic disease

authors： Piñón M,Acuña B,Lugo J,Pradas G

更新日期：2017-05-01 00:00:00

abstract：Background:Pleural fluid glucose (PFG) has diagnostic and therapeutic implications for the management of pleural effusion. The literature examining point-of-care testing of PFG is limited, and no studies exist for the bedside measurement of PFG using a glucometer (B-PFG). In this study, we compared the accuracy of B-PF...

journal_title：Journal of thoracic disease

authors： Abdo TF,Bhardwaj H,Ishaq MK,Keddissi JI,Youness HA

更新日期：2019-11-01 00:00:00

abstract：:Primary neuroendocrine tumors (NETs) of the mediastinum are very rare. Prognosis is usually poor despite treatment options. We present the case of a primary atypical carcinoid tumor of the mediastinum successfully treated by multimodal approach. A 50-year-old man presented for asthenia, dyspnea, and substernal sense o...

journal_title：Journal of thoracic disease

authors： Ventura L,Gnetti L,Silini EM,Rindi G,Carbognani P,Rusca M,Ampollini L

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:Lung ultrasound (LUS) is a clinical imaging technique for diagnosing acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). In humans and several large animals, LUS demonstrates similar specificity and sensitivity to computerized tomography (CT) scanning. Current study evaluated the degree o...

journal_title：Journal of thoracic disease

authors： Ma H,Huang D,Guo L,Chen Q,Zhong W,Geng Q,Zhang M

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:A retrospective analysis of patients undergoing cancer surgery suggested that using local anesthetics could reduce cancer recurrence and improve survival rate. Previous studies have indicated that local anesthetics may induce apoptosis in several kinds of cells in vitro, but the mechanism is unclear. METHOD...

journal_title：Journal of thoracic disease

authors： Wang HW,Wang LY,Jiang L,Tian SM,Zhong TD,Fang XM

更新日期：2016-10-01 00:00:00