Clinical efficacy and safety of nuanxin capsule for chronic heart failure: A systematic review and meta-analysis.

Abstract:

BACKGROUND:Chronic heart failure (CHF), the final phase of various heart diseases, is a serious public health problem resulting in high hospitalization rates, mortality, and increasing health care costs. Nuanxin capsule (NXC), a Chinese herbal formula, has been widely used in the treatment of CHF. However, the safety and efficacy of NXC used in patients with CHF has been uncertain and there has been no standard clinical trial published to confirm this. Thus, we conduct a study to evaluate the safety and efficacy of NXC for CHF. METHODS:The reference lists of randomized controlled trials and 8 electronic databases will be independently and systematically searched by 2 review authors in May 2018. Four English databases (EMBASE, PubMed, Cumulative Index to Nursing and Allied Health Literature [CINAHL], and Cochrane Central Register of Controlled Trials [CENTRAL]) and 4 Chinese databases (Chinese Biomedical Literature Database [CBM], Chinese National Knowledge Infrastructure [CNKI], Wanfang Database, and VIP Database) will be included. The primary outcomes will be assessed according to the function classification of New York Heart Association (NYHA). Data synthesis will be precisely computed using the RevManV5.3 software when a data-analysis is allowed. Methodological quality will be assessed according to Cochrane Handbook. RESULTS:This study will provide a high-quality synthesis of current evidence of NXC for CHF from different aspects including the mortality, the function classification of NYHA. CONCLUSION:The conclusion of this systematic review will provide evidence to prove whether NXC is an effective therapeutic intervention for patient with CHF.PROSPERO registration number: PROSPERO CRD42018090003.

journal_name

Medicine (Baltimore)

journal_title

Medicine

authors

Li Z,Zhang Y,Yuan T

doi

10.1097/MD.0000000000011339

subject

Has Abstract

pub_date

2018-07-01 00:00:00

pages

e11339

issue

27

eissn

0025-7974

issn

1536-5964

pii

00005792-201807060-00037

journal_volume

97

pub_type

杂志文章,meta分析,评审

相关文献

MEDICINE文献大全
  • Clinical feature of infertile men carrying balanced translocations involving chromosome 10: Case series and a review of the literature.

    abstract:RATIONALE:Infertile male carrying balanced translocations can be broadly divided into two types: pregestational and gestational infertility. Chromosome and breakpoints involved translocation should be considered in genetic counselling for these patients. To date, > 100 cases have been described with carrying balanced t...

    journal_title:Medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MD.0000000000010452

    authors: Zhang H,Wang R,Li L,Jiang Y,Zhang H,Liu R

    更新日期:2018-04-01 00:00:00

  • Prevalence of CD30 immunostaining in neoplastic mast cells: A retrospective immunohistochemical study.

    abstract::Mastocytosis is a rare disease characterized by clonal neoplastic proliferation of mast cells (MCs). It ranges from skin lesions as cutaneous mastocytosis (CM) which may spontaneously regress to highly aggressive neoplasms with multiorgan involvement corresponding to some aggressive systemic mastocytosis (ASM), mast c...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000010642

    authors: Russano de Paiva Silva G,Tournier E,Sarian LO,Bulai-Livideanu C,Delsol G,Lamant L,Vassallo J,Brousset P,Laurent C

    更新日期:2018-05-01 00:00:00

  • The role of NLRP3 inflammasome in stroke and central poststroke pain.

    abstract:BACKGROUND:NLRP3 inflammasome plays a prominent role in the pathogenesis and progression of many diseases, such as type 2 diabetes mellitus, obesity, atherosclerosis, and Alzheimer's disease. However, little knowledge is known about the role of NLRP3 inflammasome in central post-stroke pain (CPSP). METHODS:We selected...

    journal_title:Medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MD.0000000000011861

    authors: Li SJ,Zhang YF,Ma SH,Yi Y,Yu HY,Pei L,Feng D

    更新日期:2018-08-01 00:00:00

  • Economic and health impacts of infectious diseases in China: A protocol for systematic review and meta analysis.

    abstract:BACKGROUND:A worldwide concern has been raised that novel infectious diseases may outbreak rapidly with a limited response time due to globalization. Severe Acute Respiratory Syndrome, influenza A, Avian Influenza Virus, and Corona Virus Disease 2019 are acute respiratory diseases that have been affected by the movemen...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000021249

    authors: Li M,Fan D,Wang X

    更新日期:2020-07-24 00:00:00

  • Impacts of time interval on 18F-FDG uptake for PET/CT in normal organs: A systematic review.

    abstract:BACKGROUND:To perform a systematic review of the effect of time interval on 2-deoxy-2-[18F] fluoro-D-glucose (18F-FDG) uptake in normal organs. METHODS:PubMed, EMBASE, Ovid, and Cochrane databases were searched to identity all potential eligible literature. The study characteristics and relevant data were extracted an...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/MD.0000000000013122

    authors: Wang R,Chen H,Fan C

    更新日期:2018-11-01 00:00:00

  • Chlamydia Trachomatis Infection-Associated Risk of Cervical Cancer: A Meta-Analysis.

    abstract::As whether Chlamydia trachomatis infection increases the risk of cervical cancer is controversial in the literature, we performed a meta-analysis.Based on a comprehensive search of publications in the Medline, Cochrane, and EMBASE databases, we identified and extracted data from all relevant articles examining C. trac...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/MD.0000000000003077

    authors: Zhu H,Shen Z,Luo H,Zhang W,Zhu X

    更新日期:2016-03-01 00:00:00

  • Intra-aortic balloon pump may grant no benefit to improve the mortality of patients with acute myocardial infarction in short and long term: an updated meta-analysis.

    abstract::Intra-aortic balloon pump (IABP) has been extensively used in clinical practice as a circulatory-assist device. However, current literature demonstrated significantly varied indications for IABP application and prognosis.The objective of the study was to assess the potential benefits or risks of IABP treatment for acu...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000000876

    authors: Su D,Yan B,Guo L,Peng L,Wang X,Zeng L,Ong H,Wang G

    更新日期:2015-05-01 00:00:00

  • Comparison of the Glasgow-Blatchford and Rockall Scores for prediction of nonvariceal upper gastrointestinal bleeding outcomes in Chinese patients.

    abstract::The Glasgow-Blatchford scores (GBS) and Rockall scores (RS) are commonly used for stratifying patients with nonvariceal upper gastrointestinal hemorrhage (NVUGIH). Although predictive value of these scoring methods has been extensively validated, their clinical effectiveness remains unclear. The following study evalua...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000015716

    authors: Lu M,Sun G,Huang H,Zhang X,Xu Y,Chen S,Song Y,Li X,Lv B,Ren J,Chen X,Zhang H,Mo C,Wang Y,Yang Y

    更新日期:2019-05-01 00:00:00

  • Comparison of dual-time point 18F-FDG PET/CT tumor-to-background ratio, intraoperative 5-aminolevulinic acid fluorescence scale, and Ki-67 index in high-grade glioma.

    abstract::The aim of this study was to compare preoperative dual-time point F-fluorodeoxyglucose (FDG) uptake pattern with intraoperative 5-aminolevulinic acid (5-ALA) fluorescence in high-grade gliomas. In addition, we assessed for possible associations with a pathologic parameter (Ki-67 index).Thirty-one patients with high-gr...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000014397

    authors: Kim YI,Cho KG,Jang SJ

    更新日期:2019-02-01 00:00:00

  • Metastatic infectious disease and clinical outcome in Staphylococcus aureus and Streptococcus species bacteremia.

    abstract::Early detection of metastatic infection in patients with Gram-positive bacteremia is important as morbidity and mortality are higher in the presence of these foci, probably due to incomplete eradication of clinically silent foci during initial treatment. We performed a prospective study in 115 patients with Staphyloco...

    journal_title:Medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/MD.0b013e31824d7ed2

    authors: Vos FJ,Kullberg BJ,Sturm PD,Krabbe PFM,van Dijk APJ,Wanten GJA,Oyen WJG,Bleeker-Rovers CP

    更新日期:2012-03-01 00:00:00

  • Using a Web-Based Approach to Assess Test-Retest Reliability of the "Hypertension Self-Care Profile" Tool in an Asian Population: A Validation Study.

    abstract::Essential hypertension often requires affected patients to self-manage their condition most of the time. Besides seeking regular medical review of their life-long condition to detect vascular complications, patients have to maintain healthy lifestyles in between physician consultations via diet and physical activity, ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000002955

    authors: Koh YLE,Lua YHA,Hong L,Bong HSS,Yeo LSJ,Tsang LPM,Ong KZ,Wong SWS,Tan NC

    更新日期:2016-03-01 00:00:00

  • Efficacy of short-term nivolumab treatment in a Chinese patient with relapsed advanced-stage lung squamous cell carcinoma: A case report.

    abstract:INTRODUCTION:Currently, the options are limited for the treatment of patients who have failed 2 lines of chemotherapy for advanced lung squamous cell carcinoma (SCC). Recently, nivolumab, a fully human IgG4 programmed death 1 immune checkpoint inhibitor antibody, was approved to treat patients with advanced stage, rela...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000005077

    authors: Pi G,He H,Bi J,Li Y,Li Y,Zhang Y,Wang M,Han G,Lin C

    更新日期:2016-10-01 00:00:00

  • Prospective comparison of preference and efficacy of adalimumab and infliximab for treating ulcerative colitis naive to antitumor necrosis factor therapy.

    abstract::There have been few reports on 2 tumor necrosis factor alpha inhibitors, infliximab and adalimumab, with respect to patient preference and efficacy in ulcerative colitis (UC).We used questionnaires to evaluate the preference and reasons for drug choice between infliximab and adalimumab in UC patients naive to antitumo...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000007800

    authors: Mizoshita T,Katano T,Tanida S,Hirano A,Miyaki T,Ozeki K,Suzuki Y,Sugimura N,Kataoka H,Joh T

    更新日期:2017-08-01 00:00:00

  • Diagnostic accuracy of pediatric atypical appendicitis: Three case reports.

    abstract:RATIONALE:Acute appendicitis is one of the most common causes of acute abdomen in children, yet it is difficult to diagnose in young children because its clinical manifestations may be atypical. Here, 3 atypical clinical cases associated with appendicitis in children are reported. PATIENT CONCERN:The 1st case correspo...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000015006

    authors: Wang ZH,Ye J,Wang YS,Liu Y

    更新日期:2019-03-01 00:00:00

  • Cardiac tamponade complicating thoracentesis in a patient after left pneumonectomy: A case report.

    abstract:RATIONALE:Therapeutic or diagnostic thoracentesis is widely used in different clinical settings. Cardiac injury, a rare complication, could lead to fatal consequences. We describe a case of cardiac tamponade complicating thoracentesis that was recognized and rescued in a timely manner. PATIENT CONCERNS:A 42-year-old w...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000019778

    authors: Zheng M,Kang Y,Wang T,Wei J

    更新日期:2020-04-01 00:00:00

  • The association between weight fluctuation and all-cause mortality: A systematic review and meta-analysis.

    abstract:BACKGROUND:Many observational studies have reported an association between weight fluctuation and all-cause mortality. However, the conclusions obtained from these studies have been unclear. OBJECTIVE:The current meta-analysis aimed to clarify the association between weight fluctuation and all-cause mortality. DATA S...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000017513

    authors: Zhang Y,Hou F,Li J,Yu H,Li L,Hu S,Shen G,Yatsuya H

    更新日期:2019-10-01 00:00:00

  • Association between inflammation factors and Mycoplasma pneumoniae in children: Protocol for a systematic review.

    abstract:BACKGROUND:Several clinical studies have reported that inflammation factors (IF) are associated with Mycoplasma pneumoniae in children. However, no study systematically investigated the association between IF and M pneumoniae in pediatric population. Thus, this study will explore the association between IF and pediatri...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000015118

    authors: He JE,Qu H,Gao CY

    更新日期:2019-04-01 00:00:00

  • Transient Global Amnesia After Cerebral Angiography With Iomeprol: A Case Report.

    abstract::Transient global amnesia is now considered a very rare complication of cerebral angiography. Various etiological mechanisms have been suggested to account for this complication, but no consensus has been reached yet. This case report documents one of the few reported cases of cerebral angiography-related transient glo...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000003590

    authors: Tiu C,Terecoasă EO,Grecu N,Dorobăţ B,Marinescu AN,Băjenaru OA

    更新日期:2016-05-01 00:00:00

  • Analysis of 2 novel mutations of PHEX gene inducing X-linked dominant hypophosphatemia rickets in 2 families: Two case reports.

    abstract:RATIONALE:X-linked dominant hypophosphatemia rickets (XLH, OMIM 307800) is the most common hereditary hypophosphatemic rickets and characterized by growth retardation, skeletal malformations, dental dysplasia, spontaneous fractures and osteomalacia. PHEX gene was identified for XLH and novel mutations were consistent w...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000011453

    authors: Gao Y,Wang ZM,Li XL

    更新日期:2018-08-01 00:00:00

  • Primary cystic and solid neuroendocrine tumor of the retroperitoneum: A case report.

    abstract:RATIONALE:Primary neuroendocrine tumors (NETs) of the retroperitoneum are extremely rare. The purpose of this case report is to highlight the unusual growth pattern and radiologic features of primary retroperitoneal NETs. PATIENT CONCERNS:A 46-year-old woman was found to have a retroperitoneal cystic and solid mass du...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000024054

    authors: Shi D,Dong GQ,Shen KR,Pan Y,Wei SM,Chen Y,Yu RS

    更新日期:2021-01-15 00:00:00

  • Single-organ gallbladder vasculitis: characterization and distinction from systemic vasculitis involving the gallbladder. An analysis of 61 patients.

    abstract::Systemic vasculitis (SV) involving abdominal structures usually has a poor prognosis. Gallbladder vasculitis (GV) has been reported as part of SV (GB-SV) and focal single-organ vasculitis (GB-SOV). We analyzed clinical and histologic characteristics of patients with GV to identify features that differentiate GB-SOV fr...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000000205

    authors: Hernández-Rodríguez J,Tan CD,Rodríguez ER,Hoffman GS

    更新日期:2014-11-01 00:00:00

  • Radiographic anatomical relationship between spinous process and pedicle in thoracolumbar and lumbar spine.

    abstract::Pedicle screws are widely used in spinal surgeries, but it remains technically demanding to place. There are numerous studies on the anatomy of pedicle; however, there is very little insight on the relationship between the pedicle and the spinous process, which is an important part of the spinal posterior column.The a...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000006732

    authors: Cui X,Wang G

    更新日期:2017-05-01 00:00:00

  • Risk factors of the postoperative 30-day readmission of gastric cancer surgery after discharge: A PRISMA-compliant systematic review and meta-analysis.

    abstract:BACKGROUND:Readmission is a common postoperative adverse event. This study aimed to analyze potential risk factors for the incidence of postoperative 30-day readmission after discharge for gastric cancer patients with surgical treatment. METHODS:Those studies that reported the risk factors of gastric cancer patients w...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000014639

    authors: Wu WW,Zhang WH,Zhang WY,Yang L,Deng XQ,Zhu T

    更新日期:2019-03-01 00:00:00

  • Retrospective observational study comparing the international hip dysplasia institute classification with the Tonnis classification of developmental dysplasia of the hip.

    abstract::The Tonnis radiographic classification of developmental dysplasia of the hip (DDH) has been widely used. The International Hip Dysplasia Institute (IHDI) classification, a new classification system recently developed by the IHDI, is beginning to be applied to evaluate DDH with the absence of an ossification center. Th...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000005902

    authors: Miao M,Cai H,Hu L,Wang Z

    更新日期:2017-01-01 00:00:00

  • r-tPA with loading dose of clopidogrel and aspirin therapies for capsular warning syndrome attributed to middle cerebral artery atherosclerotic stenosis: A CARE-compliant case report.

    abstract:RATIONALE:The capsular warning syndrome (CWS) is a rare and special type of transient ischemic attacks (TIAs) syndrome. The pathophysiology of CWS is very complicate, and intracranial atherosclerotic stenosis (ICAS) is rare cause. Moreover, the effective and standard therapy has not yet been established. PATIENT CONCE...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000019247

    authors: Xu J,Zhuang M,Bao G,Zhai Y,Yang GY,Xue G,Li Q

    更新日期:2020-02-01 00:00:00

  • Management of an extensive odontogenic keratocyst: A rare case report with 10-year follow-up.

    abstract:INTRODUCTION:The odontogenic keratocyst (OKC), previously known as keratocystic odontogenic tumor has been the most disputable pathologies of the maxillofacial region. Patients with OKC are often asymptomatic but may present with pain, swelling, or discharge. Despite the aggressive nature, previous literature as early ...

    journal_title:Medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MD.0000000000017987

    authors: Khan AA,Qahtani SA,Dawasaz AA,Saquib SA,Asif SM,Ishfaq M,Kota MZ,Ibrahim M

    更新日期:2019-12-01 00:00:00

  • Why recurrence was initially suspected during colorectal cancer postoperative surveillance?: A retrospective analysis.

    abstract::Routine postoperative surveillance is recommended for the patients with colorectal cancer (CRC). This study aimed to clarify the conditions indicate initial suspicion of CRC recurrence in different preoperative serum carcinoembryonic antigen (CEA) level groups, including positive physical signs/symptoms, elevated CEA ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000022803

    authors: Hung H,You J,Chiang J,Hsieh P,Chiang S,Lai C,Tasi W,Yeh C

    更新日期:2020-10-23 00:00:00

  • Interleukin-8 gene polymorphism -251T>A contributes to Alzheimer's disease susceptibility.

    abstract:BACKGROUND:Published association studies have investigated the correlation between interleukin-8 (IL-8) gene polymorphism -251T>A and susceptibility to Alzheimer's disease (AD); however, the results are conflicting. Thus, we conducted the meta-analysis to reassess the effect of IL-8 gene -251T>A variant on the risk of ...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/MD.0000000000005039

    authors: Qin B,Li L,Wang S,Wu J,Huang Y,Zhou P,Bai J,Zheng Y

    更新日期:2016-09-01 00:00:00

  • Loss-of-function mutation of PCSK9 as a protective factor in the clinical expression of familial hypercholesterolemia: A case report.

    abstract:RATIONALE:Proprotein convertase subtilisin/kexin 9 or PCSK9 is a protein whose main function is to regulate the number of low-density lipoprotein receptors (LDLR) present on the cell surface. Loss-of-function mutations in PCSK9 have been related to low LDL-cholesterol levels and a decrease in the risk of cardiovascular...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000021754

    authors: Bayona A,Arrieta F,Rodríguez-Jiménez C,Cerrato F,Rodríguez-Nóvoa S,Fernández-Lucas M,Gómez-Coronado D,Mata P

    更新日期:2020-08-21 00:00:00

  • A case report of targeted therapy with apatinib in a patient with advanced gastric cancer and high serum level of alpha-fetoprotein.

    abstract:BACKGROUND:Alpha-fetoprotein (AFP) is an important marker for hepatocellular carcinoma, and the detection of serum AFP is currently the principle method for the diagnosis of hepatocellular carcinoma. The prevalence of gastric cancer (GC) with high level of serum AFP is extremely rare, but has unique clinical features. ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000004610

    authors: Zhu XR,Zhu ML,Wang Q,Xue WJ,Wang YW,Wang RF,Chen SY,Zheng LZ

    更新日期:2016-09-01 00:00:00