A case report of targeted therapy with apatinib in a patient with advanced gastric cancer and high serum level of alpha-fetoprotein.

abstract：:Hepatocyte nuclear factor 1 beta (HNF1B) plays an important role in embryonic development, namely in the kidney, pancreas, liver, genital tract, and gut. Heterozygous germline mutations of HNF1B are associated with the renal cysts and diabetes syndrome (RCAD). Affected individuals may present a variety of renal develo...

journal_title：Medicine

authors： Alvelos MI,Rodrigues M,Lobo L,Medeira A,Sousa AB,Simão C,Lemos MC

更新日期：2015-02-01 00:00:00

abstract：:Idiopathic pulmonary fibrosis is a chronic and irreversible respiratory disease with a high incidence worldwide and no specific treatment. Currently, the etiology and pathogenesis of this disease remain largely unknown. In main purpose of this study, bioinformatics analysis was used to uncover key genes and pathways r...

journal_title：Medicine

authors： Xu Z,Mo L,Feng X,Huang M,Li L

更新日期：2020-09-04 00:00:00

abstract：BACKGROUND:This study will examine the effects of oxymatrine on the proliferation of human liver cancer Bel-7404 cells (HLCBC). METHODS:This study will search electronic bibliographic databases available in PUBMED, EMBASE, Cochrane Library, Scopus, Cumulative Index to Nursing and Allied Health Literature, China Biolog...

journal_title：Medicine

authors： Li J,Liu ZY,Yu HB,Xue Q,Qu XS

更新日期：2020-06-05 00:00:00

abstract：:We conducted the current study to investigate the clinical, laboratory, and histologic features at presentation and the outcome of renal sarcoidosis (RS). Exhaustive retrospective data were collected by the French Sarcoidosis Group. Forty-seven adult patients were assessed (30 male/17 female, M/F ratio: 1.76). Median ...

journal_title：Medicine

authors： Mahévas M,Lescure FX,Boffa JJ,Delastour V,Belenfant X,Chapelon C,Cordonnier C,Makdassi R,Piette JC,Naccache JM,Cadranel J,Duhaut P,Choukroun G,Ducroix JP,Valeyre D

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:Unstable angina (UA) is a clinically common coronary heart disease. Zhishi xiebai guizhi decoction (ZXGD) has been widely used in the management of UA, although its effective evidence is not clear and there is no systematic review regarding its efficacy and safety. Therefore, we conduct this systematic revie...

journal_title：Medicine

authors： Tang Y,Cai H,Zhan Z,Luo Y,Huang Y,Chen D,Chen B

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:A rigid video-stylet intubation device provides safe and accurate access to the trachea by enabling visualization of the airway structures during tracheal intubation. The primary purpose of this study was to examine the effects of glycopyrrolate premedication on tracheal intubation with a rigid video-stylet....

journal_title：Medicine

authors： Cho EA,Hwang SH,Lee SH,Ryu KH,Kim YH

更新日期：2018-08-01 00:00:00

abstract：:Epidemiologic studies have reported increased incidence, prevalence and acuity of periodontitis in adults with diabetes and some have also suggested that treating periodontal disease may improve glycemic control in diabetic patients. This meta-analysis was conducted to evaluate the effects of different periodontal the...

journal_title：Medicine

authors： Wang TF,Jen IA,Chou C,Lei YP

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:This study compared the effectiveness and acceptability of all Food and Drug Administration (FDA)-recommended dose proton pump inhibitors (PPIs) in erosive esophagitis (EE): Dexlansoprazole 60 mg, Esomeprazole 40 mg, Esomeprazole 20 mg, Pantoprazole 40 mg, Lansoprazole 30 mg, Rabeprazole 20 mg, Omeprazole 20...

journal_title：Medicine

authors： Li MJ,Li Q,Sun M,Liu LQ

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Previous studies have demonstrated that single-nucleotide polymorphisms (SNPs) in miRNAs are related to the susceptibility to brain tumors, but the conclusions remain controversial. This study was to perform a meta-analysis to re-assess the associations between miRNA SNPs and brain tumor risk. METHODS:Relev...

journal_title：Medicine

authors： Gao F,Zhu Y

更新日期：2019-08-01 00:00:00

abstract：:The aim of the study was to evaluate in human immunodeficiency virus (HIV)-infected patients estimated glomerular filtration rate (eGFR) trajectories during treatment with different protease inhibitors (PIs) or a non-nucleoside reverse transcriptase inhibitor (NNRTI) plus tenofovir (TDF) or abacavir (ABC) and lamivudi...

journal_title：Medicine

authors： Gianotti N,Galli L,Poli A,Salpietro S,Nozza S,Carbone A,Merli M,Ripa M,Lazzarin A,Castagna A

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Previous studies have reported that acupuncture combined Bobath approach (BA) can be used to treat limbs paralysis (LP) after hypertensive intracerebral hemorrhage (HICH) effectively. However, no systematic review has explored its effectiveness and safety for LP following HICH. In this systematic review, we ...

journal_title：Medicine

authors： Song GF,Li X,Feng Y,Yu CH,Lian XY

更新日期：2019-03-01 00:00:00

abstract：:To investigate the differences in bone mineral density between patients with liver cirrhosis and healthy control, and to analyze the risk factors of hepatic osteoporosis in patients with HBV related liver cirrhosis.A total of 189 patients with liver cirrhosis and 207 health controls were enrolled. The bone mineral den...

journal_title：Medicine

authors： Zhang W,Gong H,Su Z,Zhang X,Cao S

更新日期：2019-08-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to observe the counter-effect of carbon monoxide-releasing molecule-2 (CORM-2) on lipopolysaccharide (LPS)-suppressed thrombomodulin (TM) and endothelial protein C receptor (EPCR) expressions from human umbilical vein endothelial cell (HUVEC), and to reveal its mechanisms. METHODS:H...

journal_title：Medicine

authors： Meng X,Fei D,Liu M,Yang S,Song N,Jiang L,Kang K,Nan C,Luo Y,Pan S,Zhao M

更新日期：2017-05-01 00:00:00

abstract：:Treatment of hypertrophic scars arising as a result of thermal burns in children is still a big problem. The results of the treatment are not satisfactory for patients and parents, and new methods of treatment are still investigated.We present the use of one of the most modern carbon dioxide (CO2) lasers (Lumenis Enco...

journal_title：Medicine

authors： Żądkowski T,Nachulewicz P,Mazgaj M,Woźniak M,Cielecki C,Wieczorek AP,Beń-Skowronek I

更新日期：2016-10-01 00:00:00

abstract：:Elevated serum homocysteine has been shown to be a risk factor for hypertension, cardiovascular disease (CVD), and type-2 diabetes mellitus (T2DM).We characterized the relationships between the serum levels of homocysteine, folic acid, and vitamins D2, D3, and B12 in patients with T2DM, CVD, and hypertension in Shangh...

journal_title：Medicine

authors： Mao X,Xing X,Xu R,Gong Q,He Y,Li S,Wang H,Liu C,Ding X,Na R,Liu Z,Qu Y

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:The process of population aging inclines to seek determinants of the quality of life in the older people. Health self-assessment is the one of the main elements of the quality of life. In the older people it is associated with functional efficiency. The aim of the study was to determine correlations of physi...

journal_title：Medicine

authors： Knapik A,Brzęk A,Famuła-Wąż A,Gallert-Kopyto W,Szydłak D,Marcisz C,Plinta R

更新日期：2019-06-01 00:00:00

abstract：ABSTRACT:Hepatic neuroendocrine tumors (HNETs) are uncommon neoplasms that can be subdivided into 2 types: primary and metastatic HNETs. Due to its rarity, heterogeneity and complexity, the diagnosis, treatment modalities and prognosis are still controversial.This retrospective study reviewed the effects of tumor origi...

journal_title：Medicine

authors： Jiao X,Luan W,Peng X,Liu L,Zhang L,Zhou L

更新日期：2020-12-18 00:00:00

abstract：:Endothelial dysfunction and chronic inflammatory process are prevalent in patients with end-stage renal disease (ESRD) on maintenance hemodialysis (HD). The aim of this study was to evaluate the acute and short-term effects of online hemodiafiltration (OL-HDF) versus conventional HD on endothelial function and inflamm...

journal_title：Medicine

authors： Jia P,Jin W,Teng J,Zhang H,Zou J,Liu Z,Shen B,Cao X,Ding X

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVES:The primary objective of this study was to investigate whether dexmedetomidine could potentiate the analgesic efficacy of ropivacaine, when added to ropivacaine for wound infiltration in patients undergoing open gastrectomy. METHODS:Fifty patients scheduled for open gastrectomy were divided into 2 equal gro...

journal_title：Medicine

authors： Luan H,Zhu P,Zhang X,Tian L,Feng J,Wu Y,Yan Y,Zhao Z,Gu X

更新日期：2017-09-01 00:00:00

abstract：:Olfactory outcomes as well as oronasal postoperative complications of transsphenoidal pituitary surgery have not been well studied. The objective of this study was to investigate nasal symptoms including olfactory function as well as quality of life following transsphenoidal pituitary surgery. The study is designed as...

journal_title：Medicine

authors： Wang S,Chen Y,Li J,Wei L,Wang R

更新日期：2015-01-01 00:00:00

abstract：:This study aimed to investigate the myocardial protective effect of liquid sodium phosphocreatine cardiac arrest in extracorporeal circulation surgery treating infants with atrial septal defects.Eighty-four infants with atrial septal defects who required extracorporeal circulation surgery treatment at our hospital fro...

journal_title：Medicine

authors： Yang F,Wang J,Zhai B

更新日期：2020-07-10 00:00:00

abstract：BACKGROUND:Anterior cruciate ligament rupture is a common motor system injury, and the most effective treatment is anterior cruciate ligament reconstruction (ACLR). Choosing the right graft is an important factor to ensure the success of the surgery. Current research shows that the clinical effect of autologous ligamen...

journal_title：Medicine

authors： Jin JX,Fang PZ,Hu ZW,Chen JL,Wang RR,Wang X

更新日期：2020-10-23 00:00:00

abstract：:Fibrosing mediastinitis (FM) is a rare disorder characterized by the invasive proliferation of fibrous tissue within the mediastinum. FM frequently results in the compression of vital mediastinal structures and has been associated with substantial morbidity and mortality. Its pathogenesis remains unknown. However, in ...

journal_title：Medicine

authors： Peikert T,Colby TV,Midthun DE,Pairolero PC,Edell ES,Schroeder DR,Specks U

更新日期：2011-11-01 00:00:00

abstract：RATIONALE:Albeit it is rare, the authors report a stage 3 Kummell disease case. It is diagnosed by dynamic thoracic magnetic resonance imaging (MRI). Because there is no established strategy on stage 3 Kummell disease, we performed percutaneous kyphoplasty at first, but unfortunately made a revision surgery to remove t...

journal_title：Medicine

authors： Zhang C,Wang G,Liu X,Li Y,Sun J

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Graves ophthalmopathy (GO) is one of the remaining enigmas in thyroidology. Glucocorticoids (GCs) are strongly recommended but their effects are not completely satisfactory and adverse reactions can occur. Tripterygium glycosides (TG) is a promising component extracted from Tripterygium wilfordii Hook F (TwH...

journal_title：Medicine

authors： Liu X,Gao C,Liu X,Gao T

更新日期：2019-12-01 00:00:00

abstract：:Although supraclavicular brachial plexus block (SCBPB) was repopularized by the introduction of ultrasound, its usefulness in shoulder surgery has not been widely reported. The objective of this study was to compare motor and sensory blockades, the incidence of side effects, and intraoperative opioid analgesic require...

journal_title：Medicine

authors： Ryu T,Kil BT,Kim JH

更新日期：2015-10-01 00:00:00

abstract：INTRODUCTION:Hypertrophic scars are a common disease in plastic surgery, which is the reaction of skin connective tissue to trauma beyond the normal range. Although scholars around the world have explored the tissue structure and formation mechanism of HS for decades, they are not satisfactory the result of. No effecti...

journal_title：Medicine

authors： Liu YH,Xiang J,Han PP,Yang C,Wang YZ,Wang W,Zhang PA

更新日期：2020-06-26 00:00:00

abstract：BACKGROUND:Characterized by diffuse hepatic fibrosis and nodule formation, hepatitis B cirrhosis (HBC), an important result of chronic hepatitis B development, mainly contains compensated and decompensated stage. Compensated cirrhosis can further develop into decompensated stage and hepatocellular carcinoma with seriou...

journal_title：Medicine

authors： Jiang X,Xie L,Huang C,Liu Y,Liu H,Liu B,Zheng L

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Percutaneous tracheostomy, almost associated with cough reflex and hemodynamic fluctuations, is a common procedure for traumatic brain injury (TBI) patients, especially those in neurosurgery intensive care units (NICUs). However, there are currently a lack of effective preventive measures to reduce the risk ...

journal_title：Medicine

authors： Gao J,Wei L,Xu G,Ren C,Zhang Z,Liu Y

更新日期：2019-08-01 00:00:00

abstract：:This article compares the clinical characteristics and prognosis of young patients in different age groups with liver cancer (LC). In this retrospective study, we searched the Surveillance, Epidemiology, and End Results population-based database and identified 2641 patients who had been diagnosed with LC between 1988 ...

journal_title：Medicine

authors： Zhang W,Jiang R,Hou J,Sun B

更新日期：2015-03-01 00:00:00