Using bioinformatics approach identifies key genes and pathways in idiopathic pulmonary fibrosis.

abstract：:There have been few reports on 2 tumor necrosis factor alpha inhibitors, infliximab and adalimumab, with respect to patient preference and efficacy in ulcerative colitis (UC).We used questionnaires to evaluate the preference and reasons for drug choice between infliximab and adalimumab in UC patients naive to antitumo...

journal_title：Medicine

authors： Mizoshita T,Katano T,Tanida S,Hirano A,Miyaki T,Ozeki K,Suzuki Y,Sugimura N,Kataoka H,Joh T

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Acute mountain sickness (AMS) is the effect when people accessing high altitude in a short period of time. As a cyclooxygenase (COX) inhibitor, ibuprofen could alleviate the symptoms of AMS. However, whether it can prevent AMS or not is still controversial. It is necessary to perform a meta-analysis to evalu...

journal_title：Medicine

authors： Yi H,Wang K,Gan X,Li L,Zhang Q,Xiang J,Yuan X,Zhang Y,Wang Y

更新日期：2020-11-13 00:00:00

abstract：BACKGROUND:Patients with HIV have been found to suffer from lipid abnormalities, including elevated levels of total and LDL-cholesterol as well as triglyceride levels. Abnormal lipid levels are associated with an increased risk of developing cardiovascular diseases, which are significant causes of mortality among the g...

journal_title：Medicine

authors： Roever L,Resende ES,Diniz ALD,Penha-Silva N,O'Connell JL,Gomes PFS,Zanetti HR,Roerver-Borges AS,Veloso FC,Fidale TM,Casella-Filho A,Dourado PMM,Chagas ACP,Ali-Hasan-Al-Saegh S,Reis PEO,Pinto RM,Oliveira GBF,Avezum Á,N

更新日期：2018-04-01 00:00:00

abstract：:Familial Mediterranean Fever is a rare disease which usually begins in childhood and occurs primarily among persons of Mediterranean ancestry. It is characterized by short, self-limited, febrile episodes that may occur alone or with inflammation of serosal surfaces. Some individuals may exhibit an erysipilas-like eryt...

journal_title：Medicine

authors： Meyerhoff J

更新日期：1980-01-01 00:00:00

abstract：INTRODUCTION:Acute hydrocephalus is a common complication of spontaneous or traumatic intracranial bleeding with extensive subarachnoid hemorrhage (SAH) or ventricular extension. However, it has never been reported to be secondary to pneumocephalus. PATIENT CONCERNS:A 32-year-old man was admitted following a motorcycl...

journal_title：Medicine

authors： Li G,Wang G,Luan T,Hou K,Yu J

更新日期：2020-01-01 00:00:00

abstract：:Cancer stem cells (CSCs) are thought to be responsible for tumor relapse and metastasis due to their abilities to self-renew, differentiate, and give rise to new tumors. Cyclooxygenase-2 (COX-2) is highly expressed in several kinds of CSCs, and it helps promote stem cell renewal, proliferation, and radioresistance. Wh...

journal_title：Medicine

authors： Guo Z,Jiang JH,Zhang J,Yang HJ,Yang FQ,Qi YP,Zhong YP,Su J,Yang RR,Li LQ,Xiang BD

更新日期：2015-11-01 00:00:00

abstract：:The neutrophil-to-lymphocyte ratio (NLR) and the platelet-to-lymphocyte ratio (PLR) are not fully evaluated for the diagnosis of musculoskeletal tumors, especially spine tumors. The objective of our study was to assess the feasibility of NLR and PLR as indicators for pretreatment diagnosis of spine tumors.Patients who...

journal_title：Medicine

authors： Li Y,Wang B,Zhou S,Jiang L,Yang S,Liu X,Wei F,Zhang H,Wang Y,Liu Z

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Polycystic ovary syndrome (PCOS) is a female endocrine disease with a high incidence. At present, drug treatment is still the main therapeutic strategy for PCOS. Traditional Chinese medicine has a long history in the treatment of menstrual disorders. Shouwu Jiangqi Decoction (SWJQD) is a traditional herbal m...

journal_title：Medicine

authors： Xu W,Tang M,Wang J,Wang L

更新日期：2020-03-01 00:00:00

abstract：:This study is to investigate the cervical human papillomavirus (HPV) infection rate in women of Urumqi, China.The epidemiological questionnaire survey was used to study 2300 women in Urumqi with a prospective research method. The second-generation hybrid capture assay, cervical liquid-based cytology test, colposcopy, ...

journal_title：Medicine

authors： Yao L,Yuan M,Yuan J,Zhou P,Mei L,Cheng J

更新日期：2018-11-01 00:00:00

abstract：:This study aimed to assess the associations of human leukocyte antigen (HLA)-DR and interleukin (IL)-18 gene polymorphisms with hepatitis B virus (HBV).Clinical data were retrospectively reviewed between December 2006 and December 2015 at Xiangyang Central Hospital. HBV patients were assigned to the high and low viral...

journal_title：Medicine

authors： Jiang H,Cao F,Cao H,Rao Q,Yang Y

更新日期：2018-07-01 00:00:00

abstract：RATIONALE:Angiosarcomas are malignant vascular tumors, and angiosarcoma occurring in the anterior mediastinum is rare. Here we report a case of angiosarcoma that originated in the anterior mediastinum treated with surgery, followed by radiotherapy and synchronous chemotherapy. PATIENT CONCERNS:A 56-year-old female was...

journal_title：Medicine

authors： Tan YB,Yu XF,Fan JQ,Li JF

更新日期：2018-12-01 00:00:00

abstract：PURPOSE:To evaluate the incidence risk of programmed cell death-1/programmed cell death ligand 1 (PD-1/PD-L1) inhibitor-related alopecia for cancer patients, the meta-analysis was put into practice. METHOD:The meta-analysis was designed and put into practice according to the preferred reporting items for systematic re...

journal_title：Medicine

authors： Li M,Huang L,Ren X,Liu L,Shi Q,Liu L,Wang X,Tian Y,Yu L,Mi F

更新日期：2020-10-16 00:00:00

abstract：:IgG4-related disease (IgG4-RD) is a novel systemic disease entity characterized by elevated serum IgG4 and tissue infiltration of IgG4-positive plasma cells accompanied by severe fibrosis. Although recent studies demonstrated that innate immune cells including monocytes and macrophages might promote local fibrosis and...

journal_title：Medicine

authors： Ohta M,Moriyama M,Maehara T,Gion Y,Furukawa S,Tanaka A,Hayashida JN,Yamauchi M,Ishiguro N,Mikami Y,Tsuboi H,Iizuka-Koga M,Kawano S,Sato Y,Kiyoshima T,Sumida T,Nakamura S

更新日期：2016-02-01 00:00:00

abstract：INTRODUCTION:Intraductal papillary neoplasms of the bile duct (IPNB) is a kind of rare disorder with low incidence but high misdiagnosis due to untypical symptoms and non-specific laboratory indicators. Herein, we report a case of cystic type IPNB with infiltrating carcinoma of the intrahepatic bile duct presented as a...

journal_title：Medicine

authors： Ma Z,Zhao F,Pan J,Lin G,Chen B,Fu W

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:According to the mechanisms of action, combination therapy of anabolic and antiresorptive agents may produce more effect for the treatment of osteoporosis. However, the combination therapy of anabolic agents and bisphosphonates reports no benefit and even reduced the anabolic effects of anabolic agents. This...

journal_title：Medicine

authors： Lou S,Wang L,Wang Y,Jiang Y,Liu J,Wang Y

更新日期：2017-12-01 00:00:00

abstract：:This article explores information relating to female adolescents knowledge, attitudes, and behaviors toward human immunodeficiency virus (HIV) and other sexually transmitted diseases (STDs) in Carriacou. The authors aimed at finding out whether adolescent females in Carriacou receive adequate information about HIV and...

journal_title：Medicine

authors： Patrice-Coy C,Johnson EJ,Boodram CAS

更新日期：2016-09-01 00:00:00

abstract：:This systematic review was performed to investigate the ethical justification, methodological quality, validity and safety of placebo controls in randomized placebo-controlled surgical trials.Central, MEDLINE, and EMBASE were systematically searched to identify randomized controlled trials comparing a surgical procedu...

journal_title：Medicine

authors： Probst P,Grummich K,Harnoss JC,Hüttner FJ,Jensen K,Braun S,Kieser M,Ulrich A,Büchler MW,Diener MK

更新日期：2016-04-01 00:00:00

abstract：:We studied 121 patients with systemic lupus erythematosus (SLE), of whom 119 were complement typed. Both black and white patients with SLE were more likely than racially matched controls to have a C4A null allotype. Patients with homozygous C4A deficiency had less proteinuria than other patients (p = 0.02) and both ho...

journal_title：Medicine

authors： Petri M,Watson R,Winkelstein JA,McLean RH

更新日期：1993-07-01 00:00:00

abstract：RATIONALE:Hereditary neuropathy with liability to pressure palsy (HNPP) is an episodic, multifocal neuropathy, with a typical clinical presentation of recurrent transient pressure palsies, which is induced by a PMP22 deletion. Another neuropathy caused by a PMP22 duplication is Charcot-Marie-Tooth disease type 1A (CMT1...

journal_title：Medicine

authors： Li J,Niu B,Wang X,Hu H,Cao B

更新日期：2017-05-01 00:00:00

abstract：:This study aimed to explore the efficacy and toxicity of image-guided stereotactic body radiotherapy (IGSBR) by helical tomotherapy in patients with lung cancer among Chinese Han population.A total of 21 patients with stage I lung cancer were included. They received a total of 60 Gy factions IGSBR. The outcomes includ...

journal_title：Medicine

authors： Chen XR,Dong JN,Zhang F,Yao TL

更新日期：2018-01-01 00:00:00

abstract：:To assess whether MR diffusion imaging may be applied for non-invasive detection of renal changes correlating with clinical diagnosis of acute kidney injury (AKI) in patients after lung transplantation (lutx).Fifty-four patients (mean age 49.6, range 26-64 years) after lutx were enrolled in a prospective clinical stud...

journal_title：Medicine

authors： Derlin K,Hellms S,Gutberlet M,Peperhove M,Jang MS,Greite R,Hartung D,Derlin T,Fegbeutel C,Tudorache I,Jüttner B,Wiese B,Lichtinghagen R,Haller H,Haverich A,Wacker F,Warnecke G,Gueler F

更新日期：2020-12-04 00:00:00

abstract：:Young children with olfactory disturbance are sometimes encountered in ENT clinics. We investigated the clinical applicability of olfactory testing to the pediatric population in China.One hundred and ninety-three healthy children aged 6 to 17 years were enrolled. All participants were asked for demographic informatio...

journal_title：Medicine

authors： Chen G,Pan H,Li L,Wang J,Zhang D,Wu Z

更新日期：2018-04-01 00:00:00

abstract：RATIONALE:Paraneoplastic cerebellar degeneration (PCD) is a rare neurodegenerative syndrome associated with antibodies targeting the Purkinje cells of the cerebellum. Most cases of anti-Yo-associated PCD occur in females, with <20 cases reported in males. Herein, we report a male patient with anti-Yo-associated PCD who...

journal_title：Medicine

authors： Hu FQ,Shang FR,Liu JJ,Yuan H

更新日期：2020-08-14 00:00:00

abstract：BACKGROUND:Renal cell carcinoma metastasizing to rectum is very rare, and the unusual metastatic sites should be paid attention to during the follow-up of renal cell carcinoma. CASE SUMMARY:We describe a case of a 65-year-old male who was diagnosed with metastatic renal cell carcinoma to rectum 10 years after the righ...

journal_title：Medicine

authors： Zheng G,Li H,Li J,Zhang X,Zhang Y,Wu X

更新日期：2017-01-01 00:00:00

abstract：RATIONALE:Compressive radial neuropathy by a synovial cyst in the radial tunnel during pregnancy is a rare occurrence. The management of radial nerve compression caused by a synovial cyst in a pregnant patient is a surgical dilemma owing to the fetal and maternal risks of treatment. PATIENT CONCERNS AND DIAGNOSIS:A 37...

journal_title：Medicine

authors： Hsiao CM,Wu CC,Wen HC

更新日期：2018-12-01 00:00:00

abstract：RATIONALE:Sternoclavicular joint septic arthritis is an unusual disease in healthy adults, and Staphylococcus aureus is the most common causative pathogen. The current treatment of choice is surgery with sternoclavicular joint resection and pectoralis flap closure, especially when the disease is complicated by osteomye...

journal_title：Medicine

authors： Kwon HY,Cha B,Im JH,Baek JH,Lee JS

更新日期：2020-10-30 00:00:00

abstract：BACKGROUND:In addition to the physical burden, the quality of life and survival in patients with cancer may also be reduced because of psychological distress, such as spiritual crisis, anxiety, and depression. Many studies have verified that spirituality could reduce anxiety and depression and improve quality of life a...

journal_title：Medicine

authors： Xing L,Guo X,Bai L,Qian J,Chen J

更新日期：2018-08-01 00:00:00

abstract：:The periaqueductal gray (PAG) plays a pivotal role in pain modulation. We attempted to examine the relation between injury of the PAG and central pain in patients with mild traumatic brain injury (TBI).Sixty-one patients with mild TBI with central pain and 31 healthy control subjects were recruited for this study. Vis...

journal_title：Medicine

authors： Jang SH,Park SM,Kwon HG

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:Current evidence concerning the association between persistent organic pollutants (POPs) and polycystic ovary syndrome (PCOS) is inconsistent. The aim of the present systematic review and meta-analysis is to evaluate the role of POPs in PCOS. METHODS:Databases including PubMed, Embase, Web of Science, and C...

journal_title：Medicine

authors： Li Y,Zhang MW,Wang YJ

更新日期：2019-08-01 00:00:00

abstract：:Myositis-specific autoantibodies, such as anti-melanoma differentiation associated gene 5 (MDA5) and anti-anti-amino acyl-tRNA synthetases (ARS) antibodies, are associated with interstitial lung diseases (ILD), which determine the prognosis of polymyositis/dermatomyositis (PM/DM) patients. However, there is a paucity ...

journal_title：Medicine

authors： Temmoku J,Sato S,Fujita Y,Asano T,Suzuki E,Kanno T,Furuya MY,Matsuoka N,Kobayashi H,Watanabe H,Koga T,Shimizu T,Kawakami A,Migita K

更新日期：2019-05-01 00:00:00