Abstract:
BACKGROUND:Many observational studies have reported an association between weight fluctuation and all-cause mortality. However, the conclusions obtained from these studies have been unclear. OBJECTIVE:The current meta-analysis aimed to clarify the association between weight fluctuation and all-cause mortality. DATA SOURCE:We electronically searched PubMed, Embase, and Web of Science for articles reporting an association between weight fluctuation and all-cause mortality that were published before April 30, 2018. STUDY APPRAISAL AND SYNTHESIS METHODS:The methodological quality of each study was appraised using the modified Newcastle Ottawa Quality Assessment Scale. The hazard ratios (HRs) and corresponding 95% confidence intervals (CIs) were extracted from the included studies and pooled using random-effect models. Meta-regression approaches were also performed to explore sources of between-study heterogeneity. RESULTS:A total of 15 studies were eligible for the current meta-analysis. The pooled overall HR for all-cause mortality in the group with the greatest weight fluctuations compared with the most stable weight category was 1.45 (95% CI: 1.29-1.63). Considerable between-study heterogeneity was observed, some of which was partially explained by the different follow-up durations used by the included studies. Moreover, publication bias that inflated the risk of all-cause mortality was detected using Egger's test (P = .001). CONCLUSION:Weight fluctuation might be associated with an increased risk of all-cause mortality.
journal_name
Medicine (Baltimore)journal_title
Medicineauthors
Zhang Y,Hou F,Li J,Yu H,Li L,Hu S,Shen G,Yatsuya Hdoi
10.1097/MD.0000000000017513subject
Has Abstractpub_date
2019-10-01 00:00:00pages
e17513issue
42eissn
0025-7974issn
1536-5964pii
00005792-201910180-00032journal_volume
98pub_type
杂志文章,meta分析相关文献
MEDICINE文献大全abstract:INTRODUCTION:Duodenal obstructions caused by congenital anatomic abnormalities are rare in adults. Several patients in whom the duodenal obstruction was caused by a congenital duodenal diaphragm have been described. The duodenal obstruction in the patient presented herein was caused by a transverse septum, which has no...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000007093
更新日期:2017-10-01 00:00:00
abstract::To review the reported evidence on the therapeutic management of IgG4-related disease (IgG4-RD) in clinical practice.A systematic search of the literature was conducted. The primary outcome measured was the rate of efficacy of first-line therapeutic approaches. Secondary outcomes measured included the rate of disease ...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000004002
更新日期:2016-06-01 00:00:00
abstract:RATIONAL:Spontaneous adrenal hematoma in pregnancy is a very rare condition. Herein we present an additional rare case of unilateral spontaneous adrenal hematoma in a pregnant woman, aiming to share this experience and summarize the signal characteristics of simple adrenal hematoma in magnetic resonance imaging (MRI). ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000013329
更新日期:2018-11-01 00:00:00
abstract:BACKGROUND:This study is to summarize the status of knowledge, attitudes, implementation, facilitators, and barriers of evidence-based practice (EBP) in community nurses (CNs). EBP has been widely adopted but the knowledge, attitudes, and implementation of EBP among CNs, and the facilitators and barriers they perceived...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000017209
更新日期:2019-09-01 00:00:00
abstract::The objective of this study was to evaluate the necessity of concurrent chemotherapy in T1-2N1 nasopharyngeal carcinoma (NPC) patients treated with intensity-modulated radiation therapy (IMRT). The retrospective analysis was conducted using the paired comparison method. We matched cases to controls using the greedy ma...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001457
更新日期:2015-09-01 00:00:00
abstract::The combination of the direct-acting antivirals, simeprevir (SMV) and sofosbuvir (SOF), was the first highly efficacious interferon-free combination for treating patients with hepatitis C virus (HCV), and was widely used in Italy as a result.The aim of this study was to evaluate effectiveness and safety of SMV in Ital...
journal_title:Medicine
pub_type: 杂志文章,多中心研究
doi:10.1097/MD.0000000000011307
更新日期:2018-07-01 00:00:00
abstract:RATIONALE:The optimal therapeutic regimen for chemotherapy-refractory and node-positive small-cell lung cancer (SCLC) is criticizable for the lack of evidence. PATIENT CONCERNS:A patient with locally advanced SCLC was insensitive to the first-line chemotherapy of etoposide, irinotecan, and cisplatin. DIAGNOSES:The pa...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000008922
更新日期:2017-11-01 00:00:00
abstract:RATIONALE:Parvovirus B19 has been linked to polyarteritis nodosa (PAN), but there is some controversy about its pathogenesis regarding whether it is triggered by the immune complex or by the activated immune cells that phagocytose viruses. PATIENT CONCERNS:A 38-year-old woman was admitted with fever and bicytopenia. S...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000022079
更新日期:2020-09-04 00:00:00
abstract::Although esophageal candidiasis (EC) is an opportunistic infection, asymptomatic EC (AEC) is occasionally encountered in otherwise healthy individuals. This study evaluates the impact of antifungal treatment in immunocompetent individuals with AEC and investigates risk factors for persistent or recurrent EC. The autho...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001969
更新日期:2015-11-01 00:00:00
abstract::This study is to investigate the relationship of P-selectin (Ps) gene rs1800807 and rs1800808 polymorphisms with plasma soluble P-selectin (sPs) in Han, Uygur, and Kazakh people with atrial fibrillation (AF) and thromboembolism (TE) in Xinjiang, China.A total of 778 Han patients (including 131 patients with AF and TE,...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000018937
更新日期:2020-01-01 00:00:00
abstract:RATIONALE:Pelvic tumor had great impact on patients' quality of life. After tumor resection, how to accurately fill bone defect remained challenging for orthopedic surgeons. Due to lack of individual design, high incidence of prosthetic mismatching, and loosening were reported in pelvic reconstruction surgery with conv...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000016658
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND:Previous clinical studies have reported that furosemide can be used to treat liver cirrhosis (LC) effectively. However, no study systematically explored this issue. This systematic review aims to investigate the efficacy and safety of furosemide for treatment of LC. METHODS:This study will be conducted thro...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000015300
更新日期:2019-04-01 00:00:00
abstract:BACKGROUND:Polycystic ovary syndrome (PCOS) is a female endocrine disease with a high incidence. At present, drug treatment is still the main therapeutic strategy for PCOS. Traditional Chinese medicine has a long history in the treatment of menstrual disorders. Shouwu Jiangqi Decoction (SWJQD) is a traditional herbal m...
journal_title:Medicine
pub_type: 杂志文章,随机对照试验
doi:10.1097/MD.0000000000019045
更新日期:2020-03-01 00:00:00
abstract::This report describes a case of d-lactic acidosis observed by the authors and then reviews all case reports of d-lactic acidosis in the literature in order to define its clinical and biochemical features and pathogenetic mechanisms. The report also reviews the literature on metabolism of d-lactic acid in humans. The c...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/00005792-199803000-00001
更新日期:1998-03-01 00:00:00
abstract:BACKGROUND:Central nervous system diseases such as stroke, spinal cord injury, traumatic brain injury, and multiple sclerosis can be fatal or cause sequelae, affecting sensorimotor and cardiorespiratory systems and quality of life. These subjects present a low response to aerobic and resistance exercise, due to decreas...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000015851
更新日期:2019-06-01 00:00:00
abstract::Disabled-2 (Dab2) is a clathrin and cargo-binding endocytic adaptor protein that plays a role in cellular trafficking of low-density lipoprotein receptor (LDLR). However, little is known about its involvement in coronary artery disease (CAD). Here, we aimed to investigate the association between Dab2 single-nucleotide...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000020924
更新日期:2020-07-02 00:00:00
abstract::This study aimed to evaluate the characteristics of parathyroid carcinoma and to validate the diagnostic value of Tc-methoxyisobutylisonitrile (MIBI) single photon emission computed tomography/x-ray computed tomography (SPECT/CT) for differentiating between parathyroid carcinoma and hyperparathyroidism. Four consecuti...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000012578
更新日期:2018-10-01 00:00:00
abstract:ABSTRACT:There is no established protocol regarding the timing of administration of antiemetics in patients undergoing total knee arthroplasty (TKA). The purpose of this study was to determine whether preoperative, rather than postoperative administration of an antiemetic could reduce postoperative nausea and vomiting ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000024143
更新日期:2021-01-08 00:00:00
abstract:ABSTRACT:To date research investigating the associations between handgrip strength and multimorbidity when stratifying by age and sex is limited. Furthermore, this is the first study in a Korean population, and the first to include adults ≥ 19 years of age. Here we investigated the associations between handgrip strengt...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000023994
更新日期:2021-01-08 00:00:00
abstract::To characterize the current frequency of HIV-1 coreceptor usage in China and assess the candidacy of CCR5 antagonists for treatment of HIV infections. In addition, we aimed to evaluate the potential of X4/DM virus transmission in recently infected men who have sex with men (MSM) individuals.Viral tropism testing was p...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000005017
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND:The study determined the effect of cognitive-behavioral therapy (CBT) with music in reducing physics test anxiety among secondary school students as measured by generalized test anxiety scale. METHODS:Pre-test post-test randomized control trial experimental design was adopted in this study. A total of 83 se...
journal_title:Medicine
pub_type: 杂志文章,随机对照试验
doi:10.1097/MD.0000000000016406
更新日期:2020-04-01 00:00:00
abstract:RATIONALE:Acute chest pain remains one of the most challenging complaints of patients presenting to emergency departments (EDs). The diverse etiologies of chest pain frequently lead to diagnostic and therapeutic challenges. Esophageal perforation is a rare but potentially life-threatening disease. It results in delayed...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000018765
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:To evaluate the efficacy and safety of dry needling (DN) for treating low back pain (LBP). METHODS:Nine databases were searched from inception to October 2017. Eligible randomized controlled trials (RCTs) involving DN for treating LBP were retrieved. Two reviewers independently screened the articles, extrac...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000011225
更新日期:2018-06-01 00:00:00
abstract:BACKGROUND:Tacrolimus was used as a rinse solution against ischaemia-reperfusion injury (IRI) in liver transplantation for years but its protective effects remain controversies. METHODS:We conducted literature retrieval in electronic databases including MEDLINE, EMBASE and Cochrane Central to identify relevant randomi...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000015809
更新日期:2019-05-01 00:00:00
abstract:BACKGROUND:Although many patients try to seek acupuncture to improve in vitro fertilization (IVF) outcomes, evidence regarding its efficacy and acupoints characters are lacking. The aim of this protocol is to evaluate the effectiveness and safety, as well as the acupoints characteristics of acupuncture in the treatment...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000010998
更新日期:2018-06-01 00:00:00
abstract::To evaluate clinical values of clinicopathologic and 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT)-related parameters for prediction of v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS) mutation in colorectal cancer (CRC) and to investigate their variability depen...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000002236
更新日期:2016-01-01 00:00:00
abstract::Colorectal neoplasm (CRN) and coronary heart disease (CHD) share common risk factors. We aimed to assess the risk for CRN in patients who are at high risk for developing CHD determined by measurements, which are independent from the risk factors for CRN.This study was conducted on individuals who underwent total colon...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000000793
更新日期:2015-05-01 00:00:00
abstract:BACKGROUND:This study was conducted with the aim to investigate the relationship between Tetranectin (TN) and efficiency of posterior spinal V osteotomy in patients with traumatic kyphosis. METHODS:Ninety-two patients with traumatic kyphosis admitted in our hospital from February 2014 to June 2016 were included whose ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000009555
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND:Flavopiridol a semisynthetic flavone that inhibits cyclin-dependent kinases (CDKs) and has growth-inhibitory activity and induces a blockade of cell-cycle progression at G1-phase and apoptosis in numerous human tumor cell lines and is currently under investigation in phase II clinical trials. Cancer stem cel...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000005150
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND:Nowadays, psychiatric morbidities are more and more common, which imposes huge social and economic burden on all countries across the world. Mental illnesses are found to be related to genetics. Over the past few years, a large number of risk genes and loci related to psychiatric morbidities have been report...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000022875
更新日期:2020-11-06 00:00:00