Transmission ratio distortion is frequent in Arabidopsis thaliana controlled crosses.

Abstract:

:The equal probability of transmission of alleles from either parent during sexual reproduction is a central tenet of genetics and evolutionary biology. Yet, there are many cases where this rule is violated. The preferential transmission of alleles or genotypes is termed transmission ratio distortion (TRD). Examples of TRD have been identified in many species, implying that they are universal, but the resolution of species-wide studies of TRD are limited. We have performed a species-wide screen for TRD in over 500 segregating F2 populations of Arabidopsis thaliana using pooled reduced-representation genome sequencing. TRD was evident in up to a quarter of surveyed populations. Most populations exhibited distortion at only one genomic region, with some regions being repeatedly affected in multiple populations. Our results begin to elucidate the species-level architecture of biased transmission of genetic material in A. thaliana, and serve as a springboard for future studies into the biological basis of TRD in this species.

journal_name

Heredity (Edinb)

journal_title

Heredity

authors

Seymour DK,Chae E,Arioz BI,Koenig D,Weigel D

doi

10.1038/s41437-018-0107-9

subject

Has Abstract

pub_date

2019-03-01 00:00:00

pages

294-304

issue

3

eissn

0018-067X

issn

1365-2540

pii

10.1038/s41437-018-0107-9

journal_volume

122

pub_type

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