Abstract:
:The equal probability of transmission of alleles from either parent during sexual reproduction is a central tenet of genetics and evolutionary biology. Yet, there are many cases where this rule is violated. The preferential transmission of alleles or genotypes is termed transmission ratio distortion (TRD). Examples of TRD have been identified in many species, implying that they are universal, but the resolution of species-wide studies of TRD are limited. We have performed a species-wide screen for TRD in over 500 segregating F2 populations of Arabidopsis thaliana using pooled reduced-representation genome sequencing. TRD was evident in up to a quarter of surveyed populations. Most populations exhibited distortion at only one genomic region, with some regions being repeatedly affected in multiple populations. Our results begin to elucidate the species-level architecture of biased transmission of genetic material in A. thaliana, and serve as a springboard for future studies into the biological basis of TRD in this species.
journal_name
Heredity (Edinb)journal_title
Heredityauthors
Seymour DK,Chae E,Arioz BI,Koenig D,Weigel Ddoi
10.1038/s41437-018-0107-9subject
Has Abstractpub_date
2019-03-01 00:00:00pages
294-304issue
3eissn
0018-067Xissn
1365-2540pii
10.1038/s41437-018-0107-9journal_volume
122pub_type
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