Mononuclear cells infiltrating human mammary carcinomas: immunohistochemical analysis with monoclonal antibodies.

abstract：:Epigenetic inactivation by aberrant DNA methylation has been reported for many microRNA genes in various human malignancies. However, relatively little is known about microRNA gene methylation in hepatocellular carcinoma (HCC). Therefore, a systematic screen for identification of aberrantly hypermethylated microRNA ge...

journal_title：International journal of cancer

authors： Anwar SL,Albat C,Krech T,Hasemeier B,Schipper E,Schweitzer N,Vogel A,Kreipe H,Lehmann U

更新日期：2013-08-01 00:00:00

abstract：:In light of recent, strong inverse findings between lifetime red wine consumption and prostate cancer among younger men, we revisited our previous cohort analysis to more thoroughly investigate red wine consumption and prostate cancer in the Health Professionals Follow-up Study (HPFS). In 1986, HPFS participants repor...

journal_title：International journal of cancer

authors： Sutcliffe S,Giovannucci E,Leitzmann MF,Rimm EB,Stampfer MJ,Willett WC,Platz EA

更新日期：2007-04-01 00:00:00

abstract：:Immunochromatographical fecal occult blood tests were shown to have higher sensitivity for detecting colorectal neoplasms than the commonly used guaiac-based test. However, positivity rates, sensitivity and specificity vary widely. We aimed to assess the reasons for this heterogeneity. Six dichotomous (qualitative) im...

journal_title：International journal of cancer

authors： Brenner H,Haug U,Hundt S

更新日期：2010-10-01 00:00:00

abstract：:Cancer survival among people with AIDS (PWA) has been described in developed countries, but there is lack of data from developing countries. The aim of this study was to evaluate survival after cancer diagnosis in PWA and compare it with people without AIDS (non-PWA) in São Paulo, Brazil. A probabilistic record linkag...

journal_title：International journal of cancer

authors： Tanaka LF,Latorre MDRDO,Gutierrez EB,Curado MP,Dal Maso L,Herbinger KH,Froeschl G,Heumann C

更新日期：2018-02-01 00:00:00

abstract：:Gene transfer is an attractive approach to fight cancer by targeting cancer cells or their vasculature. Our study reports the inhibition of tumor growth and angiogenesis by a nonviral method using dendrimers associated with 36-mer anionic oligomers (ON36) for delivering angiostatin (Kringle 1-3) and tissue inhibitor o...

journal_title：International journal of cancer

authors： Vincent L,Varet J,Pille JY,Bompais H,Opolon P,Maksimenko A,Malvy C,Mirshahi M,Lu H,Vannier JP,Soria C,Li H

更新日期：2003-06-20 00:00:00

abstract：:Rat yolk-sac tumors were induced by intraperitoneal (i.p.) displacement of the visceral yolk sac in fetectomized W/Fu rats. Serum was obtained from each female rat prior to the pregnancy preceding the tumor-inducing procedure and then once a month during the induction period. The sera were analyzed for the presence of...

journal_title：International journal of cancer

authors： Lindvall ML,Alumets J,Sjögren HO

更新日期：1987-07-15 00:00:00

abstract：:The Ontario Cancer Registry (OCR) and the Surveillance, Epidemiology and End Results (SEER) databases were used to describe temporal trends in the incidence and survival of squamous cancers of the upper aerodigestive tract (UADT) in Ontario and the US between 1984 and 2001. Between the 1984-86 and 1999-01 periods, the...

journal_title：International journal of cancer

authors： Gupta S,Kong W,Peng Y,Miao Q,Mackillop WJ

更新日期：2009-11-01 00:00:00

abstract：:Microtubule-targeted drugs are now indispensable for the therapy of various cancer types worldwide. In this article, we report MT119 [6-[2-(4-methoxyphenyl) -ethyl]-9-[(pyridine-3-ylmethyl)amino]pyrido[2',1':2,3]imida-zo[4,5-c]isoquinolin-5(6H)-one] as a new microtubule-targeted agent. MT119 inhibited tubulin polymeri...

journal_title：International journal of cancer

authors： Zhang Z,Meng T,Yang N,Wang W,Xiong B,Chen Y,Ma L,Shen J,Miao ZH,Ding J

更新日期：2011-07-01 00:00:00

abstract：:Since the investigation, at an individual level, of lifetime sun exposure remains difficult the site distribution of different types of skin cancer can be an important source of aetiological clues. The present report deals with 1,149 cases of cutaneous malignant melanoma (CMM), 7,685 of basal-cell carcinoma (BCC) and ...

journal_title：International journal of cancer

authors： Franceschi S,Levi F,Randimbison L,La Vecchia C

更新日期：1996-07-03 00:00:00

abstract：:The ganglioside composition of 20 human malignant melanomas and 5 normal tissues (muscle, spleen, kidney, liver and brain) was analyzed by high-performance thin-layer chromatography (HPTLC) and immune HPTLC using a panel of antiganglioside monoclonal antibodies, and quantified by photodensitometry. The most prominent ...

journal_title：International journal of cancer

authors： Hamilton WB,Helling F,Lloyd KO,Livingston PO

更新日期：1993-02-20 00:00:00

abstract：:Esophageal cancer is a leading cause of cancer death, especially in developing countries. In high-risk regions, squamous cell carcinoma is the most common type of esophageal cancer, and its etiology remains poorly understood. The purpose of this study was to evaluate the association between human papillomavirus (HPV) ...

journal_title：International journal of cancer

authors： Gao GF,Roth MJ,Wei WQ,Abnet CC,Chen F,Lu N,Zhao FH,Li XQ,Wang GQ,Taylor PR,Pan QJ,Chen W,Dawsey SM,Qiao YL

更新日期：2006-09-15 00:00:00

abstract：:Genome-wide association studies (GWAS) have identified several loci contributing to lung cancer and COPD risk independently; however, inflammation-related pathways likely harbor additional lung cancer risk-associated variants in biologically relevant immune genes that differ dependent on COPD. We selected single nucle...

journal_title：International journal of cancer

authors： Watza D,Lusk CM,Dyson G,Purrington KS,Wenzlaff AS,Neslund-Dudas C,Soubani AO,Gadgeel SM,Schwartz AG

更新日期：2020-08-01 00:00:00

abstract：:It is generally assumed that inflammation influences carcinogenesis. We previously reported that dextran sodium sulfate (DSS) strongly enhances colon carcinogenesis in the Apc(Min/+) mice and the over-expression of inducible nitric oxide synthase (iNOS) contributes to this enhancement. In the current study, we investi...

journal_title：International journal of cancer

authors： Kohno H,Takahashi M,Yasui Y,Suzuki R,Miyamoto S,Kamanaka Y,Naka M,Maruyama T,Wakabayashi K,Tanaka T

更新日期：2007-08-01 00:00:00

abstract：:Regulation of cell differentiation is most often impaired in malignant tumors and may represent a key mechanism for the progression of the disease. CCAAT-enhancer binding protein (C/EBP) is a family of transcription factors involved in the regulation of embryonic gut development in rodents, which has also been detecte...

journal_title：International journal of cancer

authors： Rask K,Thörn M,Pontén F,Kraaz W,Sundfeldt K,Hedin L,Enerbäck S

更新日期：2000-05-01 00:00:00

abstract：:Neuroendocrine gastrointestinal tumors take up, decarboxylate and store large amounts of monoamines. Radioactive-labeled monoamines like the norepinephrine analogue meta-iodobenzylguanidine (MIBG) have been used for the imaging of neuroendocrine tumors for many years. MIBG is selectively taken up via norepinephrine tr...

journal_title：International journal of cancer

authors： Höpfner M,Sutter AP,Beck NI,Barthel B,Maaser K,Jockers-Scherübl MC,Zeitz M,Scherübl H

更新日期：2002-09-20 00:00:00

abstract：:The effects of prolonged administration of genistein, a tyrosine-kinase inhibitor, on sodium-chloride-enhanced induction of gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine, and the labeling and apoptotic indices and vessel counts in the gastric mucosa and gastric cancers, were investigated in Wi...

journal_title：International journal of cancer

authors： Tatsuta M,Iishi H,Baba M,Yano H,Uehara H,Nakaizumi A

更新日期：1999-01-29 00:00:00

abstract：:We established gastric cancer-specific CD8+ T-cell (T(CD8+)) lines derived from different lymphocyte sources in the same patients by repeated stimulation with mitomycin-C-treated autologous tumor cells with low-dose interleukin-2, and we compared recognition patterns among the T(CD8+) derived from solid tumor, lymph n...

journal_title：International journal of cancer

authors： Kono K,Ichihara F,Iizuka H,Sekikawa T,Matsumoto Y

更新日期：1997-06-11 00:00:00

abstract：:The role of transcript variants of cyclin D1 in cancer biology is unclear. Most tumors with high levels of cyclin D1 express 2 transcripts due to alternative splicing: one full-length transcript of 4.4 kb and one short transcript of approximately 1.7 kb. The short transcript lacks part of the 3'UTR region regulating m...

journal_title：International journal of cancer

authors： Sander B,Flygare J,Porwit-Macdonald A,Smith CI,Emanuelsson E,Kimby E,Liden J,Christensson B

更新日期：2005-11-10 00:00:00

abstract：:LAF-4, which encodes a nuclear protein with transactivation potential, is fused to the MLL gene in acute lymphoblastic leukemia (ALL). We identified LAF-4 as a gene that is transcriptionally deregulated in breast tumors and thus may have a pathological role in mammary tumorigenesis. In line with the previous finding t...

journal_title：International journal of cancer

authors： To MD,Faseruk SA,Gokgoz N,Pinnaduwage D,Done SJ,Andrulis IL

更新日期：2005-07-01 00:00:00

abstract：:Serum alkaline DNase activity (SADA) was investigated in rats receiving s.c. transplants of tumor cells sensitive or resistant to chemotherapy. Serum samples from each animal were collected before transplantation, during the development of tumors and after therapy. Within a few days after transplantation of both tumor...

journal_title：International journal of cancer

authors： Economidou-Karaoglou A,Brasseur F,Lans M,Taper HS,Roberfroid MB

更新日期：1989-05-15 00:00:00

abstract：:This study investigates the clinical course of low grade squamous intraepithelial lesions (LSIL), HPV status and HPV16-specific immune response in a large prospective study of 125 women with LSIL followed cytologically, virologically and histologically. Women with low-grade abnormal smears were recruited and followed-...

journal_title：International journal of cancer

authors： Woo YL,van den Hende M,Sterling JC,Coleman N,Crawford RA,Kwappenberg KM,Stanley MA,van der Burg SH

更新日期：2010-01-01 00:00:00

abstract：:A series of 39 human brain tumors has been screened for the presence or absence of SV40-related T antigen by the direct and indirect immunoperoxidase methods. Two tumors of ependymal origin (malignant ependymoma, choroid plexus papilloma) revealed markedly positive nuclear staining for T antigen both in vivo and in vi...

journal_title：International journal of cancer

authors： Tabuchi K,Kirsch WM,Low M,Gaskin D,Van Buskirk J,Maa S

更新日期：1978-01-15 00:00:00

abstract：:Three lymphoblastoid cell lines were established from splenic lymphocytes of a lymphomatous baboon (Papio hamadryas) by co-cultivation of the lymphocytes with X-irradiated cells of marmoset or baboon lymphoblastoid cell cultures; the baboon splenic lymphocytes failed to grow when cultured alone. A herpesvirus, associa...

journal_title：International journal of cancer

authors： Falk L,Deinhardt F,Nonoyama M,Wolfe LG,Bergholz C

更新日期：1976-12-15 00:00:00

abstract：:Colorectal cancer (CRC) is the third most common cancer and the second leading cause of cancer mortality worldwide. Emerging evidence indicates that tumour cells release substantial amounts of RNA into the bloodstream, in which RNA strongly resists RNases and is present at sufficient levels for quantitative analyses. ...

journal_title：International journal of cancer

authors： Xu W,Zhou G,Wang H,Liu Y,Chen B,Chen W,Lin C,Wu S,Gong A,Xu M

更新日期：2020-05-15 00:00:00

abstract：:HER2 represents an important signaling pathway in breast and other cancers. Herceptin has demonstrated clinical activity, but resistance is common. Thus, new therapeutic approaches to the HER2 pathway are needed. Grb2 is an adaptor protein involved in Ras-dependent signaling induced by HER2 receptors. A specific Grb2-...

journal_title：International journal of cancer

authors： Gril B,Vidal M,Assayag F,Poupon MF,Liu WQ,Garbay C

更新日期：2007-07-15 00:00:00

abstract：:Effects of 12-O-tetradecanoyl phorbol 13-acetate (TPA) and the hepatic peroxisome proliferators (HPPs) clofibrate, methyl clofenapate (MCP), di(2-ethylhexyl)phthalate (DEHP) and mono(2-ethylhexyl)phthalate (MEHP) were studied in 2 gap junctional intercellular communication (GJIC) systems, metabolic cooperation in V79 ...

journal_title：International journal of cancer

authors： Cruciani V,Mikalsen SO,Vasseur P,Sanner T

更新日期：1997-10-09 00:00:00

abstract：:The survival experience of 284 patients with cancer of the cervix uteri registered by the population-based Zimbabwe National Cancer Registry in 1995-1997 is described. The vital status of these subjects was established by linkage with death registration and by retrieval of patient files from medical records department...

journal_title：International journal of cancer

authors： Chokunonga E,Ramanakumar AV,Nyakabau AM,Borok MZ,Chirenje ZM,Sankila R,Parkin DM

更新日期：2004-03-20 00:00:00

abstract：:Benzo(a)pyrene and benz(a) anthrancene which, in contrast to the K-region epoxides benzo(a)pyrene 4,5-oxide and benz(a)anthracene 5,6-oxide, are not mutagenic to Salmonella typhimurium TA 1537 in the absence of mammalian enzyme preparations, were activated by liver microsomes from C3H mice, which had not received any ...

journal_title：International journal of cancer

authors： Oesch F,Bentley P,Glatt HR

更新日期：1976-10-15 00:00:00

abstract：:Loss of heterozygosity (LOH) is an important event of tumorigenesis. In gastric cancer, we found a novel region of LOH in chromosome 9q having about 800 kb deletions at 9q31.1. The microsatellite marker D9S938 in that region exhibiting the highest LOH frequency, 56.5%. In addition, the LOH at 9q31.1 did not show any r...

journal_title：International journal of cancer

authors： Kakinuma N,Kohu K,Sato M,Yamada T,Nakajima M,Akiyama T,Ohwada S,Shibanaka Y

更新日期：2004-03-01 00:00:00

abstract：:Signal transducer and activator of transcription 3 (STAT3) is activated in a variety of human cancers, including ovarian cancer. The molecular mechanism by which the STAT3 is activated in cancer cells is poorly understood. We observed that human ovarian xenograft tumors (A2780) in mice were severely hypoxic (pO(2) app...

journal_title：International journal of cancer

authors： Selvendiran K,Bratasz A,Kuppusamy ML,Tazi MF,Rivera BK,Kuppusamy P

更新日期：2009-11-01 00:00:00