Fracture risk in young and middle-aged adults with type 1 diabetes mellitus: A systematic review and meta-analysis.

abstract：OBJECTIVE:Since panhypopituitarism in patients with Sheehan's syndrome is due to massive pituitary necrosis with only minor hypothalamic involvement, we hypothesized that serum TSH levels would be low but its circadian rhythm preserved in these patients. DESIGN AND PATIENTS:Basal and TRH-stimulated mean afternoon (150...

journal_title：Clinical endocrinology

authors： Abucham J,Castro V,Maccagnan P,Vieira JG

更新日期：1997-11-01 00:00:00

abstract：OBJECTIVE:It is known that growth hormone can induce accelerated bone turnover in GH deficient people as well as healthy elderly people. In this study we examined the effect of recombinant human GH (rhGH) on bone mineral mass and bone turnover in the presence of the bone resorption inhibiting agent, pamidronate. Effect...

journal_title：Clinical endocrinology

authors： Erdtsieck RJ,Pols HA,Valk NK,van Ouwerkerk BM,Lamberts SW,Mulder P,Birkenhäger JC

更新日期：1995-11-01 00:00:00

abstract：:Bilateral, selective and simultaneous catheterization of the inferior petrosal sinus with measurements of ACTH after stimulation with ovine corticotrophin-releasing factor (CRF) is now frequently used to establish the differential diagnosis in patients with Cushing's disease and to determine the side of the microadeno...

journal_title：Clinical endocrinology

authors： Schulte HM,Allolio B,Günther RW,Benker G,Winkelmann W,Ohnhaus EE,Reinwein D

更新日期：1988-03-01 00:00:00

abstract：BACKGROUND:Aromatase deficiency (AD) caused by cytochrome P450 family 19 subfamily A polypeptide 1 (CYP19A1) variants is characterized by a deficiency in androgen-to-oestrogen conversion. OBJECTIVE:To investigate the clinical characteristics and accurate management of aromatase-deficient children. PATIENTS AND METHOD...

journal_title：Clinical endocrinology

authors： Fan L,Zhang B,Li L,Gong C

更新日期：2020-12-01 00:00:00

abstract：:A 30-year-old presented in 1984 with a clinically nonfunctional tumour which subsequently developed into a metastatic corticotrophinoma from which he died despite surgery in 1984, 1986 and 1991 and external radiotherapy in 1986. Molecular genetic analysis of tumour and metastatic tissue revealed loss of heterozygosity...

journal_title：Clinical endocrinology

authors： Bates AS,Buckley N,Boggild MD,Bicknell EJ,Perrett CW,Broome JC,Clayton RN

更新日期：1995-06-01 00:00:00

abstract：:A A 23-year-old man with secondary hypogonadism was also found to be thyrotoxic. Results of thyroid function tests were in the hyperthyroid range but the serum TSH was inappropriately high. A pituitary tumour was demonstrated and following hypophysectomy he became biochemically hypothyroid. Evidence is presented and d...

journal_title：Clinical endocrinology

authors： Baylis PH

更新日期：1976-03-01 00:00:00

abstract：OBJECTIVE:Stimulation with corticotropin-releasing hormone (CRH) is one of principal tools for the differential diagnosis of ACTH-dependent Cushing's syndrome. However, different dosages and species of CRH may be employed; further, ACTH levels can be measured by radioimmunoassay (RIA) or immunoradiometric assay (IRMA)....

journal_title：Clinical endocrinology

authors： Pecori Giraldi F,Invitti C,Cavagnini F,Study Group of the Italian Society of Endocrinology on the Pathophysiology of the Hypothalamic-pituitary-adrenal axis.

更新日期：2001-05-01 00:00:00

abstract：OBJECTIVE:Results from the published studies on the association of adiponectin gene (ADIPOQ) polymorphisms with blood lipids and blood pressure are conflicting. We investigated the association of three ADIPOQ polymorphisms, +45 T > G (rs2241766), +276 G > T (rs1501299) and -11377 C > G (rs266729), with these traits in ...

journal_title：Clinical endocrinology

authors： Zhao T,Zhao J

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVE:The objective of the present study was to elucidate the parathyroid responsiveness by measurements of blood ionized calcium and serum intact parathyroid hormone (PTH) concentrations, before and during trisodium citrate induced hypocalcaemia. PATIENTS AND CONTROLS:Sixteen patients with primary hyperparathyroi...

journal_title：Clinical endocrinology

authors： Schwarz P,Sørensen HA,Momsen G,McNair P,Transbøl I

更新日期：1992-10-01 00:00:00

abstract：OBJECTIVES:We wished to determine whether women with multinodular goitre and spontaneous subclinical hyperthyroidism have decreased bone density. DESIGN AND SUBJECTS:Bone density was measured at the distal and proximal forearm. Data were expressed as Z-scores relative to the mean values out of 125 control subjects mat...

journal_title：Clinical endocrinology

authors： Mudde AH,Reijnders FJ,Kruseman AC

更新日期：1992-07-01 00:00:00

abstract：OBJECTIVE:The purpose of the current study was to investigate the diagnostic performance of high mobility group A2 (HMGA2) gene expression for differentiation of malignant thyroid nodules through a systematic review and meta-analysis. DESIGN:The MEDLINE/PubMed and EMBASE database, from the earliest available date of i...

journal_title：Clinical endocrinology

authors： Kim BH,Kim SJ,Kim M,Lee SW,Jeong SY,Pak K,Kim K,Kim IJ

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:Hypopituitarism diagnosed in childhood, adolescence and young adulthood has the potential to affect growth and somatic development. Less is known about the impact of such a diagnosis on other aspects of development. DESIGN:An analysis of the KIMS database (Pfizer International Metabolic Database) was perform...

journal_title：Clinical endocrinology

authors： Mitra MT,Jönsson P,Åkerblad AC,Clayton P,Kołtowska-Häggström M,Korbonits M,Toogood A,Gleeson H

更新日期：2017-04-01 00:00:00

abstract：:The response of serum calcium, PTH, CT and gastrin to an infusion of secretin (3 CU/kg/h) over a period of 90 min was studied in ten healthy males and two female patients with hypoparathyroidism. In the healthy males serum calcium, after a transient fall, significantly increased at 45 min after the onset of the infusi...

journal_title：Clinical endocrinology

authors： Lo Cascio V,Piubello W,Cominacini L,Vantini I,Galvanini G,Ederle A,Cavallini G,Scuro LA

更新日期：1982-04-01 00:00:00

abstract：BACKGROUND:Hydrocortisone therapy should be individualized in congenital adrenal hyperplasia (CAH) patients to avoid over and under replacement. We have assessed how differences in absorption and half-life of cortisol influence glucocorticoid exposure. PATIENTS AND METHODS:Forty-eight patients (21 M) aged between 6·1 ...

journal_title：Clinical endocrinology

authors： Hindmarsh PC,Charmandari E

更新日期：2015-04-01 00:00:00

abstract：:Although vasomotor instability or hot flushes are a well-known occurrence in women with natural or artificially-induced menopause, they have not previously been described in children. We report three children in different stages of puberty who developed vasomotor instability following surgery involving the hypothalami...

journal_title：Clinical endocrinology

authors： Witt MF,Blethen SL

更新日期：1983-06-01 00:00:00

abstract：OBJECTIVE:To study the relationship between maternal thyrotrophin (TSH) and breech presentation at term. DESIGN:Combined data sets of two prospective studies to obtain adequate epidemiological power. PATIENTS:One thousand and fifty-eight healthy pregnant women (58 breech, 1000 cephalic) and 131 women who presented in...

journal_title：Clinical endocrinology

authors： Kooistra L,Kuppens SM,Hasaart TH,Vader HL,Wijnen HA,Oei SG,Pop VJ

更新日期：2010-11-01 00:00:00

abstract：:Insulin-like growth factor-II (IGF-II) is a widely expressed 7·5 kDa mitogenic peptide hormone. Although it is abundant in serum, understanding of its physiological role is limited compared with that of IGF-I. IGF-II regulates foetal development and differentiation, but its role in adults is less well understood. Evid...

journal_title：Clinical endocrinology

authors： Livingstone C,Borai A

更新日期：2014-06-01 00:00:00

abstract：:Autoantibodies to thyroid peroxidase (TPO), the thyroid 'microsomal' antigen, are widely utilized in the diagnosis of human autoimmune thyroid disease. Crude human thyroid preparations of TPO are of differing potency, contain residual thyroglobulin (Tg) and other human membrane antigens, and are available in only limi...

journal_title：Clinical endocrinology

authors： Kendler DL,Martin A,Magnusson RP,Davies TF

更新日期：1990-12-01 00:00:00

abstract：:A single-dose study was performed to examine the pharmacokinetics of subcutaneous octreotide in acromegalic patients and to investigate the relationship between growth hormone and the elimination half-life of the drug. Fourteen acromegalic patients (six men and eight women; age range 35-59 years) who had previously re...

journal_title：Clinical endocrinology

authors： Nicholls J,Wynick D,Domin J,Sandler LM,Bloom SR

更新日期：1990-05-01 00:00:00

abstract：OBJECTIVES:There is growing evidence for the association between bone mineral density (BMD) and vascular calcification, which is related to cardiovascular disease. Coronary multidetector row computed tomography (MDCT) is a noninvasive tool developed to evaluate coronary status precisely. We used MDCT to evaluate this a...

journal_title：Clinical endocrinology

authors： Choi SH,An JH,Lim S,Koo BK,Park SE,Chang HJ,Choi SI,Park YJ,Park KS,Jang HC,Shin CS

更新日期：2009-11-01 00:00:00

abstract：:A 32-year-old Caucasian male, clinically euthyroid, with paranoid schizophrenia and granulocytopenia, had elevated total and free serum T4 and T3; serum TSH was normal (2.7 +/- 0.7 micronU/ml). There was no goitre present, no evidence of Graves' disease, and no evidence of pituitary tumour. He had a normal response to...

journal_title：Clinical endocrinology

authors： Tamagna EI,Carlson HE,Hershman JM,Reed AW

更新日期：1979-05-01 00:00:00

abstract：OBJECTIVE:Nonsurgical hypoparathyroidism (NS-HypoPT) and pseudohypoparathyroidism (PHP) are rare diseases, with a prevalence of 2/100.000 and 1/100.000, respectively. Only few studies on Quality of Life (QoL) among patients with Ns-HypoPT and PHP are available. We aimed to investigate the QoL among patients with Ns-Hyp...

journal_title：Clinical endocrinology

authors： Underbjerg L,Sikjaer T,Rejnmark L

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVE:To assess the efficacy and safety of prenatal dexamethasone treatment in offspring at risk for congenital adrenal hyperplasia. METHODS:MEDLINE, EMBASE, the Cochrane Library, the clinicaltrials.gov website databases were systematically searched from inception through March 2019. WMD and SMD with 95%CIs were c...

journal_title：Clinical endocrinology

authors： Xu L,Lin W,Cai L,Huang H,Liang J,Li L,Zong L,Wang N,Wen J,Chen G

更新日期：2020-02-01 00:00:00

abstract：OBJECTIVE:Women with impaired glucose tolerance (IGT) and type 2 diabetes (T2D) are more at risk of cardiovascular disease. The aim of this study was to test the hypothesis that increased visceral adipose tissue (VAT) could explain to a large extent alterations in the cardiovascular disease risk profile of postmenopaus...

journal_title：Clinical endocrinology

authors： Lemieux S,Bédard A,Piché MÈ,Weisnagel SJ,Corneau L,Bergeron J

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVE:To analyse the effectiveness of age on HbA1c as a criterion for the diagnosis of diabetes in Chinese different age subjects. METHODS:This retrospective study enrolled a total of 1147 outpatients with untreated newly diagnosed diabetes (aged 18-80 years, 42·55% women) from the Fujian Province, China, and 427 ...

journal_title：Clinical endocrinology

authors： Yang L,Shen X,Yan S,Xu F,Wu P

更新日期：2015-02-01 00:00:00

abstract：OBJECTIVE:Testosterone replacement is generally considered likely to be required only at testicular radiation doses in excess of 20Gy. Long-term data are not available for patients receiving 9-14.4Gy as part of Total Body Irradiation in childhood. DESIGN:Retrospective cohort study. DATA COLLECTION:notes review, labor...

journal_title：Clinical endocrinology

authors： Taneja S,Rao A,Nussey S,Leiper A

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVE:To compare effectiveness and tolerability of quinagolide (CV 205-502) and cabergoline (CAB) treatments in 39 patients with prolactinoma. STUDY DESIGN:All 39 patients were treated first with quinagolide for 12 months and then with cabergoline for 12 months. A wash-out period was performed in all patients afte...

journal_title：Clinical endocrinology

authors： Di Sarno A,Landi ML,Marzullo P,Di Somma C,Pivonello R,Cerbone G,Lombardi G,Colao A

更新日期：2000-07-01 00:00:00

abstract：CONTEXT:Unlike pituitary macroadenomas, microadenomas (micros) are not commonly associated with hypopituitarism. In clinical practice, we have observed that patients with ACTH-secreting micros have a higher than expected prevalence of central hypothyroidism (HT), and we speculated that this effect might be because of g...

journal_title：Clinical endocrinology

authors： Mathioudakis N,Thapa S,Wand GS,Salvatori R

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:Growth hormone deficiency (GHD) in adults has been associated with impaired health status and quality of life (QoL) in several studies using generic measures, and in a few studies using recently developed disease-specific measures. Theoretically, disease-specific measures may be more sensitive and succinct th...

journal_title：Clinical endocrinology

authors： Wirén L,Whalley D,McKenna S,Wilhelmsen L

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:Graves' Ophthalmopathy (GO) is a complex eye and orbital disorder that is uniquely linked to Graves' Hyperthyroidism (GH) and has traditionally been considered a cross-reactive immune response against the thyroid stimulating hormone receptor (TSHR) in orbital tissue. However, because there is no direct evide...

journal_title：Clinical endocrinology

authors： Wescombe L,Lahooti H,Gopinath B,Wall JR

更新日期：2010-10-01 00:00:00