Abstract:
:The effects of extraction techniques on the physicochemical properties, antioxidant activity and antihyperglycemic activity of comfrey polysaccharides (CPs) were evaluated. Four techniques were used to extract CPs: hot water extraction (HW), ultrasonic-assisted extraction (UA), enzyme-assisted extraction (EA) and enzyme-ultrasonic-assisted extraction (EUA). Experimental results indicated that CPs extracted by the UA (UA-CPs) and EUA methods (EUA-CPs) had higher extraction yields. The four CPs showed the same monosaccharide composition but a significant difference in monosaccharide content. CPs showed antioxidant activities and antihyperglycemic activities in a concentration-dependent manner. UA-CPs exhibited better antioxidant capacity, which might have been related to its smaller molecular weight and higher uronic acid content. In addition, UA-CPs showed notable α-glucosidase inhibition activity. These results suggested that ultrasonic-assisted extraction technology was more beneficial to enhance the extraction yields of the polysaccharides, and obtain higher bioactive polysaccharides from comfrey.
journal_name
Int J Biol Macromoljournal_title
International journal of biological macromoleculesauthors
Duan M,Shang H,Chen S,Li R,Wu Hdoi
10.1016/j.ijbiomac.2018.04.188subject
Has Abstractpub_date
2018-08-01 00:00:00pages
876-882eissn
0141-8130issn
1879-0003pii
S0141-8130(18)30889-4journal_volume
115pub_type
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