Physicochemical properties and activities of comfrey polysaccharides extracted by different techniques.

Abstract:

:The effects of extraction techniques on the physicochemical properties, antioxidant activity and antihyperglycemic activity of comfrey polysaccharides (CPs) were evaluated. Four techniques were used to extract CPs: hot water extraction (HW), ultrasonic-assisted extraction (UA), enzyme-assisted extraction (EA) and enzyme-ultrasonic-assisted extraction (EUA). Experimental results indicated that CPs extracted by the UA (UA-CPs) and EUA methods (EUA-CPs) had higher extraction yields. The four CPs showed the same monosaccharide composition but a significant difference in monosaccharide content. CPs showed antioxidant activities and antihyperglycemic activities in a concentration-dependent manner. UA-CPs exhibited better antioxidant capacity, which might have been related to its smaller molecular weight and higher uronic acid content. In addition, UA-CPs showed notable α-glucosidase inhibition activity. These results suggested that ultrasonic-assisted extraction technology was more beneficial to enhance the extraction yields of the polysaccharides, and obtain higher bioactive polysaccharides from comfrey.

journal_name

Int J Biol Macromol

authors

Duan M,Shang H,Chen S,Li R,Wu H

doi

10.1016/j.ijbiomac.2018.04.188

subject

Has Abstract

pub_date

2018-08-01 00:00:00

pages

876-882

eissn

0141-8130

issn

1879-0003

pii

S0141-8130(18)30889-4

journal_volume

115

pub_type

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