Isolation, qualitative and quantitative evaluation of galactomannan during germination of Trigonella persica (Fabaceae) seed.

Abstract:

:Galactomannan extracted from Trigonella persica endosperm like to other galactomannans is useful in the medicine and pharmaceutical industry such as drug delivery due to its unique physicochemical properties. As soon as germination takes place, the hydrolysis of galactomannan begins and its structure changes. Evaluation of galactomannan content extracted from the germinating seeds (GEGS) and the non-germinated seeds (GENGS) showed that the amount of galactomannan was highest at 24 h after imbibition and was completely consumed approximately 48 h after imbibition. It seems that galactomannan is used for storage reserve synthesis in the cotyledon during germination. Based on the quantitative assessment, FT-IR, macroscopic and microscopic observations, galactomannan of T. persica seeds have high an M/G ratio (approximately 5:1) and this ratio does not alter during germination. Therefore, changes in galactomannan structure (functional group and band) caused that GEGS have different physicochemical properties than GENGS. Based on the results, GENGS with a high M/G ratio may be suitable for drug delivery system due to some properties such as high viscosity and gelling.

journal_name

Int J Biol Macromol

authors

Bakhshy E,Zarinkamar F,Nazari M

doi

10.1016/j.ijbiomac.2019.06.225

subject

Has Abstract

pub_date

2019-09-15 00:00:00

pages

286-295

eissn

0141-8130

issn

1879-0003

pii

S0141-8130(19)33277-5

journal_volume

137

pub_type

杂志文章
  • Development of zolmitriptan loaded PLGA/poloxamer nanoparticles for migraine using quality by design approach.

    abstract::The purpose of this investigation was to develop Poly (D,L Lactide-co-Glycolide) (PLGA)/poloxamer nanoparticles (NPs) of the hydrophilic drug Zolmitriptan using quality-by-design approach for brain targeting. Randomized 2(4) full factorial design was employed to achieve the critical quality attributes of minimized par...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2015.12.069

    authors: Girotra P,Singh SK,Kumar G

    更新日期:2016-04-01 00:00:00

  • Alginate based tamoxifen/metal dual core-folate decorated shell: Nanocomposite targeted therapy for breast cancer via ROS-driven NF-κB pathway modulation.

    abstract::Breast cancer endocrine resistance prevents unleashing full capabilities of Tamoxifen (TMX), besides TMX off-target side effects on healthy tissue. In this study, we engineered TMX nanocomposite via co-loading it on alginate-based silver nanoparticles and embedding within folic acid-polyethylene glycol surface conjuga...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2019.12.266

    authors: Ibrahim OM,El-Deeb NM,Abbas H,Elmasry SM,El-Aassar MR

    更新日期:2020-03-01 00:00:00

  • TRIP13 is a predictor for poor prognosis and regulates cell proliferation, migration and invasion in prostate cancer.

    abstract::Thyroid hormone receptor interactor 13 (TRIP13) has been reported to be overexpressed in serval types of human cancers, and regulate tumor cell proliferation, migration and invasion. However, the role of TRIP13 in prostate cancer was still unclear. In our study, the correlation between TRIP13 expression and clinical p...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2018.09.168

    authors: Dong L,Ding H,Li Y,Xue D,Li Z,Liu Y,Zhang T,Zhou J,Wang P

    更新日期:2019-01-01 00:00:00

  • Conformational rearrangements of G-quadruplex topology promoted by Cu(II) 12-MCCu(II)PyrAcHA-4 metallacrown.

    abstract::Cu(II) 12-MCCu(II)PyrAcHA-4 metallacrown was studied by several spectroscopic techniques as an interacting ligand with G-quadruplex DNA structures. Investigations were performed on oligonucleotides bearing human telomeric and protooncogenic c-myc sequences in buffered solution mimicking ionic conditions in cellular en...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2019.11.163

    authors: Rajczak E,Juskowiak B

    更新日期:2020-08-01 00:00:00

  • Gelatin-chitosan-pectin films incorporated with rosemary essential oil: Optimized formulation using mixture design and response surface methodology.

    abstract::The aim of this study was to optimize the mechanical and texture properties of edible film improving its antibacterial property after adding rosemary essential oil (REO) using a Doehlert matrix. Films with the highest mechanical properties were acquired using a polymer composition of 65.2% glycerol, 24.3% gelatin, 10....

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2020.03.092

    authors: Yeddes W,Djebali K,Aidi Wannes W,Horchani-Naifer K,Hammami M,Younes I,Saidani Tounsi M

    更新日期:2020-07-01 00:00:00

  • Fabrication of cationic nanostructures from short self-assembling amphiphilic mixed α/β-pentapeptide: Potential candidates for drug delivery, gene delivery, and antimicrobial applications.

    abstract::The present article describes designing and fabrication of nanostructures from a mixed α/β-pentapeptide, Lys-βAla-βAla-Lys-βAla, which majorly contains non-natural β-alanine residues in the backbone with two α-lysine residues at 1- and 4-positions. The amphiphilic pentapeptide showed the ability to self-assemble into ...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2018.01.079

    authors: Goel R,Garg C,Gautam HK,Sharma AK,Kumar P,Gupta A

    更新日期:2018-05-01 00:00:00

  • Preparation of Ag-cellulose nanocomposite for the selective detection and quantification of mercury at nanomolar level and the evaluation of its photocatalytic performance.

    abstract::Mercury is a toxic heavy metal that reaches to the water bodies mainly by coal burning, mining and petrol refining. The study was focused to investigate the application of Ag-cellulose nanocomposite to detect and quantify mercury colorimetrically. The Ag-cellulose nanocomposite was characterized by X-ray diffraction, ...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2020.07.119

    authors: Balasurya S,Syed A,Thomas AM,Bahkali AH,Al-Rashed S,Elgorban AM,Raju LL,Das A,Khan SS

    更新日期:2020-12-01 00:00:00

  • Bicistronic DNA vaccine macromolecule complexed with poly lactic-co-glycolic acid-chitosan nanoparticles enhanced the mucosal immunity of Labeo rohita against Edwardsiella tarda infection.

    abstract::DNA vaccine is an important tool to elicit both humoral and cellular immunity. Present study investigates mucosal immune response of Labeo rohita (15 ± 04 g) to plasmid DNA (pDNA) vaccine macromolecule complexed with nanoparticles (NPs). Poly lactic-co-glycolic acid (PLGA), Chitosan (Chit) and PLGA-Chit-NPs were synth...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2020.04.048

    authors: Leya T,Ahmad I,Sharma R,Tripathi G,Kurcheti PP,Rajendran KV,Bedekar MK

    更新日期:2020-08-01 00:00:00

  • Characterization of disintegrated bacterial cellulose nanofibers/PVA bionanocomposites prepared via ultrasonication.

    abstract::With the increasing demand for simple, efficient, environmentally friendly preparation methods to produce cellulose nanofibers for reinforcing a biodegradable film is increased, the role of nanofibers from the pure cellulose produced by bacteria becomes more important. This work characterized bacterial cellulose nanof...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2019.05.178

    authors: Abral H,Kadriadi,Mahardika M,Handayani D,Sugiarti E,Muslimin AN

    更新日期:2019-08-15 00:00:00

  • Cell-specific and pH-sensitive nanostructure hydrogel based on chitosan as a photosensitizer carrier for selective photodynamic therapy.

    abstract::The major problems of porphyrins as promising materials for photodynamic therapy (PDT) are their low solubility, subsequently aggregation in biological environments, and a lack of tumor selectivity. With this in mind, a chitosan-based hydrogel conjugated with tetrakis(4-aminophenyl)porphyrin (NH2-TPP) and 2,4,6-tris(p...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2017.12.169

    authors: Belali S,Karimi AR,Hadizadeh M

    更新日期:2018-04-15 00:00:00

  • Sappanone A prevents hypoxia-induced injury in PC-12 cells by down-regulation of miR-15a.

    abstract:OBJECTIVE:We aimed to explore the effect of Sappanone A on neurologic damage induced by hypoxia. METHODS:PC-12 cells were pre-treated with Sappanone A and were simulated by hypoxia. miRNA transfection was performed to overexpress or suppress the expression of miR-15a in PC-12 cells. Cell viability, apoptosis, migratio...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2018.11.002

    authors: Kang C,Gao J,Kang M,Liu X,Fu Y,Wang L

    更新日期:2019-02-15 00:00:00

  • Anti-tumor and macrophage activation induced by alkali-extracted polysaccharide from Pleurotus ostreatus.

    abstract::Pleurotus ostreatus is popularly consumed as traditional medicine and health food for enhancing immune function in China. Polysaccharides from mushroom have been demonstrated to possess a wide range of health beneficial properties. This study was carried out to elucidate the immunomodulating effects and molecular mech...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2014.05.045

    authors: Kong F,Li FE,He Z,Jiang Y,Hao R,Sun X,Tong H

    更新日期:2014-08-01 00:00:00

  • Molecular complexes of calf thymus DNA with various bioactive compounds: Formation and characterization.

    abstract::The interaction between biomacromolecules and ligands has attracted great interest because of their biological properties. Calf thymus DNA (ctDNA) can interact with bioactive compounds to form complexes. Here, ctDNA-ligand complexes were studied using fluorescence, absorption, and infrared spectroscopy, circular dichr...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2020.11.135

    authors: Ji C,Yin X,Duan H,Liang L

    更新日期:2021-01-31 00:00:00

  • Inhibitory kinetics and bioactivities of Nuciferine and Methyl Ganoderate on Mucor miehei lipase and 3T3-L1 preadipocytes.

    abstract::In this study, inhibitory kinetics of Nuciferine and Methyl Ganoderate extrated from Lotus Leaves and Ganoderma lucidum on Mucor miehei Lipase were studied first. The molecular structure of Nuciferine and Methyl Ganoderate were determined. The inhibitory effects of two extracts on lipase were reversible, with the IC50...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2020.09.127

    authors: Liu XT,Liu TT,Xu HL,Chen QX,Wang Q

    更新日期:2020-11-15 00:00:00

  • Antioxidant and anti-aging activities of polysaccharides from Cordyceps cicadae.

    abstract::Cordyceps cicadae is a traditional Chinese medicine with high nutritional value and biological activities. Previously, we reported on the antioxidant activity associated with the polysaccharides from Cordyceps cicadae (CP). To further explore which of the fraction of CP had the greatest potency, in here, the in vitro ...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2020.04.163

    authors: Zhu Y,Yu X,Ge Q,Li J,Wang D,Wei Y,Ouyang Z

    更新日期:2020-08-15 00:00:00

  • Overexpressed LRIG3 gene ameliorates prostate cancer through suppression of cell invasion and migration.

    abstract::Prostate cancer (PC) is one of the most common human malignancies, which has been steadily rising among males in many countries. The leucine-rich repeats and immunoglobulin-like domains (LRIG) genes were applied in the prognosis of different types of cancers, including PC. In that case, this study is supposed to inves...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2018.11.028

    authors: Chen Y,Wang Q,Wang M,Li M

    更新日期:2019-03-01 00:00:00

  • Cloning, expression and characterization of β- and γ‑carbonic anhydrase from Bacillus sp. SS105 for biomimetic sequestration of CO2.

    abstract::Bacterium Bacillus sp. SS105, isolated from Free Air CO2 Enriched (FACE) soil was previously screened for carbonic anhydrase activity and CO2 sequestration. In this study, strain was selected to amplify carbonic anhydrase encoding genes. The CA genes from Bacillus sp. SS105 were found to be homologous with beta‑carbon...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2019.03.082

    authors: Maheshwari N,Kumar M,Thakur IS,Srivastava S

    更新日期:2019-06-15 00:00:00

  • Rheology and microstructure of myofibrillar protein-starch composite gels: Comparison of native and modified starches.

    abstract::Composite gels were prepared from 2% myofibrillar protein (MP) imbedded with native starch (potato or tapioca starch) or their modified starches in 0.6 M NaCl at pH 6.2. The role of native starch (potato or tapioca) and their modified counterparts in the rheology and microstructure of MP gels was evaluated. Dynamic rh...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2018.06.173

    authors: Wu M,Wang J,Ge Q,Yu H,Xiong YL

    更新日期:2018-10-15 00:00:00

  • Structural characterisation and immunomodulatory activity of a neutral polysaccharide from Sambucus adnata Wall.

    abstract::A neutral polysaccharide, SPW-2, was purified from the leaves of Sambucus adnata Wall. using water extraction and alcohol precipitation, Sevage deproteination, ion exchange chromatography and gel filtration chromatography. This molecule had an average molecular weight of 7040 Da and was composed of arabinose, xylose, ...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2019.11.021

    authors: Yuan L,Zhong ZC,Liu Y

    更新日期:2020-07-01 00:00:00

  • Microbial production of four biodegradable siderophores under submerged fermentation.

    abstract::Four siderophore analogues were isolated and purified from Escherichia coli, Bacillus spp. ST13, and Streptomyces pilosus microorganisms under some specific submerged fermentation conditions. In order to evaluate the highest production of this siderophore analogues through the growth, a rapid spectrophotometric screen...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2016.03.011

    authors: Fazary AE,Al-Shihri AS,Alfaifi MY,Saleh KA,Alshehri MA,Elbehairi SE,Ju YH

    更新日期:2016-07-01 00:00:00

  • Mechanism of solvent induced thermal stabilization of papain.

    abstract::In the present study an attempt is made to elucidate the effects of various cosolvents, such as sorbitol, sucrose, xylose and glycerol, on papain. The stabilizing effects of these cosolvents on the structure and function of papain is determined by the activity measurements, fluorescence spectroscopy and differential s...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2007.05.009

    authors: Sathish HA,Kumar PR,Prakash V

    更新日期:2007-10-01 00:00:00

  • Implications for glycosylated compounds and their anti-cancer effects.

    abstract::Glycosylated compounds are major secondary metabolites of plants, which have various therapeutic effects on human diseases, by acting as anti-cancer, antioxidant, and anti-inflammatory agents. Glycosylation increases stability, bioactivity, and solubility of compounds and improves their pharmacological properties. Two...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章,评审

    doi:10.1016/j.ijbiomac.2020.06.281

    authors: Pourakbari R,Taher SM,Mosayyebi B,Ayoubi-Joshaghani MH,Ahmadi H,Aghebati-Maleki L

    更新日期:2020-11-15 00:00:00

  • Cellulose nanofibril-based aerogel derived from sago pith waste and its application on methylene blue removal.

    abstract::Sago pith cellulose nanofibril (SPCNF) aerogel derived from sago pith waste (SPW) was successfully produced through three consecutive steps, namely dewaxing and delignification, ultra-sonication and homogenization and freeze drying. The aerogel was characterized using field emission scanning electron microscopy (FE-SE...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2020.05.227

    authors: Beh JH,Lim TH,Lew JH,Lai JC

    更新日期:2020-10-01 00:00:00

  • Antibacterial multilayer films fabricated by LBL immobilizing lysozyme and HTCC on nanofibrous mats.

    abstract::Cellulose acetate nanofibrous mats were prepared by electrospunning technique. Positively charged and negatively charged composites were alternately deposited on negatively charged CA mats via layer-by-layer self-assembly technique. The morphology and inhibition rate of samples were investigated by regulating number o...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2012.10.024

    authors: Huang W,Li X,Xue Y,Huang R,Deng H,Ma Z

    更新日期:2013-02-01 00:00:00

  • Molecular α-relaxation process of exopolysaccharides extracted from Nostoc commune cyanobacteria.

    abstract::Broadband dielectric spectroscopy was used to investigate the molecular α-relaxation of the exopolysaccharides (EPS) extracted from Nostoc commune cyanobacteria. The EPS were modified in different ways. EPS were carboxymethylated to obtain carboxymethyl-exopolysaccharides (CEPS). EPS and CEPS were doped with ammonium ...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2020.07.268

    authors: Gonzales KN,Troncoso OP,Torres FG,López D

    更新日期:2020-10-15 00:00:00

  • The effect of plasticizers on thermoplastic starch films developed from the indigenous Ethiopian tuber crop Anchote (Coccinia abyssinica) starch.

    abstract::Anchote (Coccinia abyssinica) starch films were prepared by a solution casting method with glycerol, 1-ethyl-3-methylimidazolium acetate, sorbitol or triethylene glycol as plasticizers. The effect of these plasticizers and their concentration on film microstructure, thermal, and mechanical properties was investigated....

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2020.03.218

    authors: Abera G,Woldeyes B,Demash HD,Miyake G

    更新日期:2020-07-15 00:00:00

  • Surface characteristics of polyurethane elastomers based on chitin/1,4-butane diol blends.

    abstract::Biodegradable polyurethane elastomers with tunable hydrophobicity were synthesized by step-growth polymerization techniques using poly(epsilon-caprolactone) (PCL) and 4,4'-diphenylmethane diisocyanate (MDI). The prepolymer was extended with different mass ratios of chitin and 1,4-butane diol (BDO). The effect of chiti...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2008.12.004

    authors: Zia KM,Barikani M,Zuber M,Bhatti IA,Barmar M

    更新日期:2009-03-01 00:00:00

  • Elucidation of cellular uptake and intracellular trafficking of heparosan polysaccharide-based micelles in various cancer cells.

    abstract::Heparosan polysaccharide, known as a heparin precursor, can be used in drug delivery systems due to its good biocompatibility and anti-cancer effect. But few studies on the cellular uptake mechanism of heparosan polysaccharide-based nanocarrier have been investigated. Therefore, the intracellular trafficking and the u...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2019.02.133

    authors: Qiu L,Shan X,Long M,Ahmed KS,Zhao L,Mao J,Zhang H,Sun C,You C,Lv G,Chen J

    更新日期:2019-06-01 00:00:00

  • Refined structure of the acetazolamide complex of human carbonic anhydrase II at 1.9 A.

    abstract::The binding of acetazolamide to human carbonic anhydrase II (HCA II) has been investigated by X-ray crystallography. The atomic positions of the enzyme inhibitor complex have been refined at 1.9 A resolution using the least squares refinement program package PROLSQ. The crystallographic R-factor is 17.6%. The bound in...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/0141-8130(90)90040-h

    authors: Vidgren J,Liljas A,Walker NP

    更新日期:1990-12-01 00:00:00

  • Genome-wide identification and transcriptional profiling of small heat shock protein gene family under diverse abiotic stress conditions in Sorghum bicolor (L.).

    abstract::The small heat shock proteins (sHsps/Hsp20s) are the molecular chaperones that maintain proper folding, trafficking and disaggregation of proteins under diverse abiotic stress conditions. In the present investigation, a genome-wide scan revealed the presence of a total of 47 sHsps in Sorghum bicolor (SbsHsps), distrib...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章

    doi:10.1016/j.ijbiomac.2019.10.023

    authors: Nagaraju M,Reddy PS,Kumar SA,Kumar A,Rajasheker G,Rao DM,Kavi Kishor PB

    更新日期:2020-01-01 00:00:00