Abstract：
:Osteonecrosis of the femoral head (ONFH) is a significant cause of both pain and disability that often affects young adults during what ought to be their most productive age. Two broad categories of ONFH exist: traumatic and non-traumatic. Traumatic ONFH results from acute mechanical disruption of the femoral head's blood supply. Many factors that increase the risk of non-traumatic osteonecrosis have been identified. Steroid-induced osteonecrosis of the femoral head (SONFH) is the most common form of non-traumatic ONFH. Many hypotheses as to the pathogenesis of SONFH have been proposed, including intravascular thrombosis, abnormal fat metabolism, intramedullary adipocyte hypertrophy, and osteoporosis; however, the exact mechanism of SONFH is still not clearly understood. Animal models using rats, mice, rabbits, chickens, pigs, and emus have been used to study SONFH. Unfortunately, these models each have limitations. Therefore, it is necessary to establish a reproducible model that better simulates human disease. The present review is intended to summarize the currently available models, evaluative indicators, and application of current understanding to both the prevention and treatment of SONFH.
journal_name
Int Orthopjournal_title
International orthopaedicsauthors
Xu J,Gong H,Lu S,Deasey MJ,Cui Qdoi
10.1007/s00264-018-3956-1subject
Has Abstractpub_date
2018-07-01 00:00:00pages
1729-1737issue
7eissn
0341-2695issn
1432-5195pii
10.1007/s00264-018-3956-1journal_volume
42pub_type
杂志文章,评审abstract：:From 1996 to 2000, we reoperated nine patients totally dissatisfied after previous surgery for cubital tunnel syndrome. All patients had simple external neurolysis in situ of the transposed ulnar nerve. Only the anterior aspect of the ulnar nerve was dissected and released. Dense scarring around the ulnar nerve was fo...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/s00264-004-0589-3
更新日期：2004-12-01 00:00:00
abstract：PURPOSE:Relatively little is known about the extent to which periprosthetic joint infections (PJI) affect the patient's long-term quality of life (QoL). Our study aim was to assess the effect of a periprosthetic infection on our patients' QoL. METHODS:We collected data retrospectively of patients who had undergone sur...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/s00264-013-2265-y
更新日期：2014-05-01 00:00:00
abstract：:In this prospective case series we evaluated the effectiveness and safety of using an anterior approach to paediatric supracondylar humerus fractures. We gathered data on 46 children that had a displaced supracondylar fracture of the humerus. All the patients had sustained a Gartland type III extension fracture that c...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/s00264-008-0668-y
更新日期：2009-10-01 00:00:00
abstract：PURPOSE:To evaluate the effects of rotator cuff tear (RCT) and its severity on shoulder proprioception. METHODS:We studied 132 consecutive patients (67 M-65 F; mean age ± SD, 66.03 ± 9.04; range, 43-78) who underwent arthroscopic rotator cuff repair. Tear size was determined intra-operatively. The control group includ...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/s00264-018-4150-1
更新日期：2019-01-01 00:00:00
abstract：PURPOSE:We report our experience analysing the risk of fracture amongst allografts in limb-preserving surgery for bone tumours. METHODS:We retrospectively reviewed our experience with bone allograft and its major complications when used for limb -preserving operations for bone tumours. Forty-one structural allografts ...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/s00264-015-2980-7
更新日期：2015-11-01 00:00:00
abstract：:Trauma, infection, local injections and even acupuncture may cause fibrosis of the muscles of the first web space of the hand, leading to severe malposition and loss of function of the thumb and index finger. The authors present the anatomical basis for the deformity and the results of surgical treatment by tenotomy o...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/BF00266837
更新日期：1984-01-01 00:00:00
abstract：:Old age is frequently associated with a poorer functional outcome after THA. This might be based upon muscular damage resulting from surgical trauma. Minimally invasive approaches have been widely promoted on the basis of the muscle sparing effect. The aim of the study was to evaluate of the functional outcome and the...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/s00264-010-1166-6
更新日期：2011-02-01 00:00:00
abstract：:This transtrochanteric approach to the hip maintains continuity between the greater trochanter and the vastus lateralis muscle, thereby preventing the gross displacement of the greater trochanter and preserving the branches of the lateral circumflex vessels to it. The procedure offers the advantages of easy exposure a...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/BF00265739
更新日期：1988-01-01 00:00:00
abstract：AIM OF THE STUDY:The aim of the study was to investigate functional and patient-rated outcome parameters after endoscopic assisted release of the ulnar nerve for cubital tunnel syndrome. METHODS:One hundred of 204 consecutive patients between 2006 and 2011 met the inclusion/exclusion criteria. Fifty-one of these patie...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/s00264-018-3760-y
更新日期：2018-06-01 00:00:00
abstract：:Between 1987 and 1991 the spine was stabilised in 205 patients using corundum ceramic implants. The radiological results were assessed with a follow up of from 6 to 24 months and were graded as good in 81%. Poor results were not due to the implanted material, but were usually caused by failure to obtain full correctio...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/BF00180170
更新日期：1994-02-01 00:00:00
abstract：PURPOSE:Hip-joint empyema is a severe local infection that can cause general illness and, in the worst-case scenario, death by septic complications. For severe hip-joint infections, the Girdlestone arthroplasty has been an established treatment option for many decades. We describe functional midterm results after treat...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/s00264-011-1351-2
更新日期：2012-05-01 00:00:00
abstract：:The effect of a low dose of diclofenac sodium, administered locally, on heterotopic bone formation in rats was investigated. Heterotopic bone was induced by implantation of demineralised bone matrix into the gluteal muscles. Diclofenac was released continuously for 2 weeks from micro-osmotic pumps for each demineralis...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/BF00178357
更新日期：1995-01-01 00:00:00
abstract：PURPOSE:To evaluate the influence of stem offset and neck shaft angles on the range of motion before component impingement (ROMCI) and bony impingement (ROMBI), and the types of impingement in total hip arthroplasty (THA). METHODS:Using the computed tomography data of 101 patients who underwent THA, three-dimensional ...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/s00264-015-2826-3
更新日期：2016-02-01 00:00:00
abstract：PURPOSE:Treatment of open fractures is complex and controversial. The purpose of the present study is to add evidence to the management of open tibial fractures, where tissue loss necessitates cover with a free flap. We identified factors that increase the risk of complications. We questioned whether early flap coverag...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/s00264-015-2712-z
更新日期：2015-06-01 00:00:00
abstract：PURPOSE:Cup positioning is important for optimum hip stability, avoiding component impingement and decreasing both bearing surface wear and revision rate. Transitioning from posterior approach in a lateral position to direct anterior approach (DAA) in a supine presents unique challenges for surgeons. The aim of this st...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/s00264-020-04583-0
更新日期：2020-09-01 00:00:00
abstract：PURPOSE:Bone morphogenetic proteins (BMP) are recombinant osteoinductive proteins with their primary role being to promote bone formation. The off-label use of BMP in orthopaedic surgery has dramatically increased. However, reports of complications with BMP have emerged, and the safety of these proteins in orthopaedics...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/s00264-014-2534-4
更新日期：2014-12-01 00:00:00
abstract：:Short stem prostheses that preserve the femoral neck are becoming more and more popular. The CFP (collum femoris preserving) has been introduced especially for the treatment of younger patients. However, information about remodelling, complications and learning curve are thus far rare. We present a retrospective study...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/s00264-010-1020-x
更新日期：2011-05-01 00:00:00
abstract：:We treated 25 patients with aggressive and malignant fibular tumours between April 1989 and May 2001. There were 11 osteosarcomas, seven Ewing's sarcoma and five chondrosarcomas. The tumours predominantly involved the upper one third; 16 were of Stage IIB. Neo-adjuvant and adjuvant chemotherapy were given to all patie...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/s00264-004-0566-x
更新日期：2004-10-01 00:00:00
abstract：PURPOSE:Acetabular bone loss is a challenging problem in revision total hip arthroplasty (rTHA). Severe bone loss is not uncommon especially in periprosthetic joint infection. Surgical options, including revision shells, rings, and cages-with or without bone allograft-are affected by high complication rates and unsatis...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/s00264-020-04623-9
更新日期：2020-10-01 00:00:00
abstract：PURPOSE:Surgical treatment of acetabular fractures with plate fixation is challenging for orthopaedic surgeons because of variations of the surface curvature and complex fracture patterns of the acetabulum. We present our experience with pre-operative computer-assisted virtual simulation and three-dimensional (3D) prin...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/s00264-018-4111-8
更新日期：2019-08-01 00:00:00
abstract：INTRODUCTION:The two-stage revision protocol is the gold standard for controlling and treating low-grade prosthetic joint infections of total hip and total knee arthroplasty. The antibiotic pause for diagnostic reasons before reconstruction (stage two) is discussed in relation to the persistence of the infection and th...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/s00264-017-3700-2
更新日期：2018-02-01 00:00:00
abstract：PURPOSE:Although previously frozen shoulder was thought to resolve by two to three years, recent studies demonstrated the symptoms can remain for much longer. Manipulation under anaesthetic (MUA) has been shown to be successful in relieving pain and restoring function. Yet, concerns have been raised regarding its safet...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/s00264-017-3558-3
更新日期：2018-02-01 00:00:00
abstract：PURPOSE:Acute compartment syndrome is a condition whereby tissue ischaemia occurs due to increased pressure in a closed myofascial compartment. It is a surgical emergency, with rapid recognition and treatment-the keys to good outcomes. METHODS:The available literature on diagnostic aids was reviewed by one of the seni...
journal_title：International orthopaedics
pub_type： 杂志文章,评审
doi：10.1007/s00264-019-04386-y
更新日期：2019-11-01 00:00:00
abstract：PURPOSE:Tibial fractures are the most common lower limb fractures. Some criteria such as open fractures and increasing open stage are known to be associated with high delayed union and pseudarthrosis rate. In cases of delayed or nonunion, classical treatment is autologous cancelous bone graft which is associated with h...
journal_title：International orthopaedics
pub_type： 杂志文章,评审
doi：10.1007/s00264-014-2342-x
更新日期：2014-09-01 00:00:00
abstract：PURPOSE:Rheumatoid arthritis has been associated with poor clinical outcomes in hemiarthroplasty and unconstrained total shoulder arthroplasty. The reverse shoulder arthroplasty can be utilized to address the shortcomings of hemiarthroplasty and unconstrained total shoulder arthroplasty in the inflammatory arthritis pa...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/s00264-019-04373-3
更新日期：2019-11-01 00:00:00
abstract：:A case of bilateral habitual dislocation of the patella associated with cleft lip and palate, and short metatarsals, metacarpals and phalanges is reported. The possible cause of habitual dislocation is discussed in the light of 20 cases which have been seen by the author. ...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/BF00183358
更新日期：1990-01-01 00:00:00
abstract：:After division of the tendo achilles in rats heterotopic bone forms in the muscle and in the tendon stumps. Tenotomy was performed in 26 male rats. Thirteen received Verapamil (36 mm/Kg) for six days per week for five months, and the remainder were not given this drug. The onset of heterotopic ossification was monitor...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/BF00182655
更新日期：1990-01-01 00:00:00
abstract：PURPOSE:Treatment of focal full-thickness chondral or osteochondral defects of the talus remains a challenge. The aim of this study was to evaluate the postoperative success and the long-term efficacy of matrix associated autologous chondrocyte implantation in these defects. METHODS:Matrix associated autologous chondr...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/s00264-012-1635-1
更新日期：2012-11-01 00:00:00
abstract：PURPOSE:We have developed iodine-supported titanium implants that suppress microbial activities and conducted in vivo and in vitro studies to determine their antimicrobial properties. METHODS:The implants were Ti-6Al-4 V titanium implants either untreated (Ti), treated with oxide film on the Ti surface by anodization ...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/s00264-017-3477-3
更新日期：2017-06-01 00:00:00
abstract：:Thirty six patients with a chronic slip of the capital femoral epiphysis and a femoral headneck angle of more than 30 degrees, as measured in a lateral radiograph, were treated by intertrochanteric osteotomy. The patients had an abnormal gait, an average age of 14.1 years and symptoms for an average of 14.5 months. Th...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/BF00180203
更新日期：1992-01-01 00:00:00
