Abstract:
:The effect of a low dose of diclofenac sodium, administered locally, on heterotopic bone formation in rats was investigated. Heterotopic bone was induced by implantation of demineralised bone matrix into the gluteal muscles. Diclofenac was released continuously for 2 weeks from micro-osmotic pumps for each demineralised bone implant in the rats. Each had a control implant in the opposite gluteal muscle to which saline was released in the same way. The yield of new woven bone was determined after 4 weeks by measuring the ash-weights of the implants. Those of the diclofenac samples were significantly decreased compared to the controls. These results suggest that a low dose of diclofenac given locally decreases heterotopic bone formation in rats.
journal_name
Int Orthopjournal_title
International orthopaedicsauthors
Risto O,Wahlström O,Abdiu Adoi
10.1007/BF00178357subject
Has Abstractpub_date
1995-01-01 00:00:00pages
392-5issue
6eissn
0341-2695issn
1432-5195journal_volume
19pub_type
杂志文章abstract::We treated 25 patients with aggressive and malignant fibular tumours between April 1989 and May 2001. There were 11 osteosarcomas, seven Ewing's sarcoma and five chondrosarcomas. The tumours predominantly involved the upper one third; 16 were of Stage IIB. Neo-adjuvant and adjuvant chemotherapy were given to all patie...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-004-0566-x
更新日期:2004-10-01 00:00:00
abstract::Twenty-eight (11 cemented and 17 noncemented) total hip arthroplasties (THA) were performed in 20 patients with rheumatoid arthritis (RA). The average age at operation was 42.1 years and the average follow-up was 10.8 years. There were two deep infections requiring removal of the prosthesis. Three cemented acetabular ...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s002640000214
更新日期:2001-01-01 00:00:00
abstract:PURPOSE:To compare the results of two groups of patients affected by osteochondritis dissecans (OCD) of the knee and treated with either osteochondral autologous transplantation (OAT) or bone-cartilage paste grafting (PG). METHODS:A total of 27 patients affected by OCD lesions of the femoral condyles were included: 15...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-020-04804-6
更新日期:2021-02-01 00:00:00
abstract::Dislocation of the elbow associated with radial head and coronoid fracture, the so-called "terrible triad" of the elbow, is challenging to treat and has a history of complicated outcomes. However, advances in the knowledge of elbow kinematics combined with improved implants and surgical techniques during the past few ...
journal_title:International orthopaedics
pub_type: 杂志文章,评审
doi:10.1007/s00264-010-1024-6
更新日期:2011-06-01 00:00:00
abstract::As part of the international campaign of the bone and joint decade, we aimed to present epidemiological data on the prevalence of major joint complaints in a Central European region. Ten thousand subjects aged between 14 and 65, selected randomly by the Hungarian central office of statistics from three counties in sou...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-005-0033-3
更新日期:2006-04-01 00:00:00
abstract::Pyogenic spondylitis is a neurological and life threatening condition. It encompasses a broad range of clinical entities, including pyogenic spondylodiscitis, septic discitis, vertebral osteomyelitis, and epidural abscess. The incidence though low appears to be on the rise. The diagnosis is based on clinical, radiolog...
journal_title:International orthopaedics
pub_type: 杂志文章,评审
doi:10.1007/s00264-011-1384-6
更新日期:2012-02-01 00:00:00
abstract:PURPOSE:Patient-specific instrumentation (PSI) was usually applied in total knee arthroplasty (TKA) to acquire a favourable alignment. We hypothesized that using PSI had a potential risk of notching in the anterior femoral cortex, because the femoral component may be placed in an overextension position due to the dista...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-020-04779-4
更新日期:2020-12-01 00:00:00
abstract::The purpose of this study was to evaluate the effects of partial and full weightbearing after cementless total hip arthroplasty over a two year follow-up period. Fifty-nine women and 41 men (average age 61 years) received an uncemented Spotorno stem and were randomised into a full and a partial weightbearing group. No...
journal_title:International orthopaedics
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s00264-010-1089-2
更新日期:2011-08-01 00:00:00
abstract::Twenty three patients with lumbar spondylolisthesis (6 Grade I, 14 Grade II and 3 Grade III) with low back pain, and radicular pain in 14, were treated surgically when they failed to respond to conservative treatment. Their average age was 33.2 years. Bilateral posterolateral spinal fusions with autologous iliac bone ...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s002640050249
更新日期:1998-01-01 00:00:00
abstract:PURPOSE:Traditional classification systems for tibial plateau fractures (TPF) are based on simple radiographs, and intra- and inter-observer variability is low. The aim was to assess intra- and inter-observer variability using traditional systems and some recently described classification systems of TPF in the interpre...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-017-3462-x
更新日期:2017-06-01 00:00:00
abstract:PURPOSE:Approximately 5% of patients with spinal tuberculosis will develop a severe kyphotic deformity resulting in increased potential for pain, spinal cord compression, cardiopulmonary dysfunction, costopelvic impingement and cosmetic concerns. This manuscript reviews the evaluation and surgical management of tubercu...
journal_title:International orthopaedics
pub_type: 杂志文章,评审
doi:10.1007/s00264-011-1292-9
更新日期:2012-02-01 00:00:00
abstract::Varus knee deformity is very common, and it can be classified according to the severity and reducibility of the deformity. Pre-operative planning is mandatory to obtain a good result. Both clinical and radiological planning should be carefully performed, particularly focused on collateral ligament deficiency. In most ...
journal_title:International orthopaedics
pub_type: 杂志文章,评审
doi:10.1007/s00264-018-4116-3
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:Several factors affect injury types in childhood. The aim of the study was to evaluate the musculoskeletal injury types, treatment modalities, and demographic characteristics of refugee children and to reveal the differences from native children. METHODS:A total of 1297 patients (897 females, 400 males) treate...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-021-04950-5
更新日期:2021-01-23 00:00:00
abstract:PURPOSE:The aim of the present study was to compare the clinical outcomes of mobile-bearing unicompartmental knee arthroplasty (MB-UKA) and open-wedge high tibial osteotomy (OWHTO) for advanced isolated medial osteoarthritis (OA). METHODS:Patients with advanced medial compartment OA (Ahlbäck grade ≥ II) who underwent ...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-018-3880-4
更新日期:2018-10-01 00:00:00
abstract:PURPOSE:The use of total hip arthroplasty (THA) to treat advanced tuberculous arthritis, particularly during the active phase, is challenging. The aim of this study was to evaluate the efficacy of cementless THA for advanced hip joint tuberculosis. METHODS:This study reviewed 32 patients (mean age at surgery, 49.4 yea...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-015-2997-y
更新日期:2015-11-01 00:00:00
abstract:PURPOSE:The purpose of this study was to analyze the occurrence of PE after intra-operative O-arm navigation-assisted surgery and determine whether the post-operative PE incidence could be decreased by using O-arm navigation as compared to conventional free-hand technique. METHODS:A cohort of 27 patients with spinal d...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-018-3889-8
更新日期:2018-09-01 00:00:00
abstract:PURPOSE:Sciatic nerve palsy after periacetabular osteotomy (PAO) is a serious complication. The purpose of this study was to determine whether a multimodal sciatic monitoring technique allows for identification of surgical steps that place the sciatic nerve at risk. METHODS:Transcranial electrical motor evoked potenti...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-016-3394-x
更新日期:2017-08-01 00:00:00
abstract::The aim of our study was to determine the radiographic prevalence of hip and knee osteoarthritis and compare our results with prevalence data reported by other studies, as no similar study had been performed in Hungary previously. Our aim was also to investigate the usefulness of the different radiological scoring met...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-010-1069-6
更新日期:2011-07-01 00:00:00
abstract:PURPOSE:In order to test the validity of the selected surgical technique as a way to manage persistent synovitis of the knee joint, as well as to slow down the cartilage and bone destruction, we studied the dynamics of biomarkers of inflammatory conditions, and bone and cartilage destruction after total arthroscopic sy...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-017-3634-8
更新日期:2017-11-01 00:00:00
abstract:BACKGROUND:To investigate the clinical effect of modified Judet quadricepsplasty (MJ) combined with patella traction designed by ourselves in the treatment of knee joint rigidity after a femoral fracture. METHODS:We retrospectively reviewed the clinical data of 21 patients with stiff knee joint after a femoral fractur...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-020-04823-3
更新日期:2020-09-24 00:00:00
abstract:PURPOSE:There remains controversy as to whether computer-navigated total knee replacement (TKR) improves the overall prosthesis alignment and patient function. The aim of this study was to determine whether computer-assisted total knee arthroplasty provides superior prosthesis positioning when compared to a conventiona...
journal_title:International orthopaedics
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00264-013-1996-0
更新日期:2014-02-01 00:00:00
abstract:PURPOSE:Aseptic loosening is a serious complication after total joint arthroplasty. Plain radiography, along with clinical signs of prosthesis loosening, is the technique of first choice to evaluate loosening of joint replacements. Nevertheless, radiographical signs of osteolysis may not be apparent until progressed st...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-014-2471-2
更新日期:2014-12-01 00:00:00
abstract:BACKGROUND:Surgical management of humeral fractures associated with radial nerve palsy remains controversial. Some advocate surgical treatment in emergency while others recommend nonoperative treatment. PURPOSE:The aim of the study was to assess nerve recovery in a series of patients treated with open reduction and in...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-015-2745-3
更新日期:2015-08-01 00:00:00
abstract:PURPOSE:Pelvic ring fractures, occurring in elderly patients are a challenging problem. Little known is about the patient-related outcome after these injuries. The primary objective of this study is to evaluate the quality of life after pelvic ring injuries in patients aged over 60 years. METHODS:Patients (≥ 60 years)...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-018-4030-8
更新日期:2019-02-01 00:00:00
abstract::Trauma, infection, local injections and even acupuncture may cause fibrosis of the muscles of the first web space of the hand, leading to severe malposition and loss of function of the thumb and index finger. The authors present the anatomical basis for the deformity and the results of surgical treatment by tenotomy o...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/BF00266837
更新日期:1984-01-01 00:00:00
abstract:PURPOSES:We investigated sequential levels of C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) in uncomplicated ACDF (anterior cervical discectomy and fusion) using allograft and DBM (demineralised bone matrix) for primary cervical spondylosis and/or disc herniation. To our knowledge, there has been no...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-012-1645-z
更新日期:2012-11-01 00:00:00
abstract:PURPOSE:To investigate the effects of genetic factors on idiopathic scoliosis (IS) and genetic modes through genetic epidemiological survey on IS in Chongqing City, China, and to determine whether SH3GL1, GADD45B, and FGF22 in the chromosome 19p13.3 are the pathogenic genes of IS through genetic sequence analysis. MET...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-011-1419-z
更新日期:2012-06-01 00:00:00
abstract:PURPOSE:The purpose of this systematic review and meta-analysis of randomised controlled trials is to assess the effectiveness of no drainage when compared to drainage in total knee arthroplasty, in terms of recovery of knee flexion, reduction in swelling, length of hospital stay and haemoglobin levels following TKA. ...
journal_title:International orthopaedics
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s00264-014-2455-2
更新日期:2015-04-01 00:00:00
abstract:PURPOSE:Total hip arthroplasty with a dual mobility cup (DMC) is a proposed alternative to the widely performed bipolar hemiarthroplasty (BHA) for treating displaced intracapsular femoral neck fractures (DFNF) in the elderly. However, the comparison between the two modalities has not been extensively conducted thus far...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-018-3767-4
更新日期:2018-06-01 00:00:00
abstract::Synovial oedema is a frequent complication in arthroscopic procedures performed with normal saline as the irrigating fluid. The authors have studied the effect of saline solution, Ringer lactate, 5% Dextran and 10% Dextran in normal saline on 12 specimens of human synovial membrane. They found that 10% Dextran in norm...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:
更新日期:1986-01-01 00:00:00