Abstract:
PURPOSE:In order to test the validity of the selected surgical technique as a way to manage persistent synovitis of the knee joint, as well as to slow down the cartilage and bone destruction, we studied the dynamics of biomarkers of inflammatory conditions, and bone and cartilage destruction after total arthroscopic synovectomy (TAS) of the knee joint. METHODS:The sampling comprised 124 RA patients (158 knees) who had undergone the TAS procedure between 2003 and 2015. Before surgery the rheumatoid factor (IgM), C-reactive protein (CRP), erythrocyte sedimentation rate test was completed for all patients. Blood serum samples were collected (prior to surgery, and three, six and 12 months after surgery) and frozen at -70°С. The content of CRP, Matrix metalloproteinase-3 (MMP-3), Cartilage Oligomeric Matrix Protein, as well as cross-linked Ctelopeptides of types I and II were measured in blood serum by means of polarization fluoroimmunoassay with the use of a standard set of reagents. RESULTS:The average duration of the disease in the studied group was 8.7 ± 6.6 years. Concentration of the inflammation markers showed that only MMP-3 displayed statistical significance. CONCLUSIONS:The obtained results can be used as basis in assessing the efficiency and effectiveness of this method of treatment of persistent knee joint synovitis associated with the RA.
journal_name
Int Orthopjournal_title
International orthopaedicsauthors
Lipina M,Makarov M,Makarov S,Novikov Adoi
10.1007/s00264-017-3634-8subject
Has Abstractpub_date
2017-11-01 00:00:00pages
2259-2264issue
11eissn
0341-2695issn
1432-5195pii
10.1007/s00264-017-3634-8journal_volume
41pub_type
杂志文章abstract:PURPOSE:Indications for amputation in natural disasters are not the same compared to our daily practice. They must be determined by those with great surgical experience and good knowledge of military or disaster surgical doctrine. Unfortunately, nowadays few surgeons have this experience. In fact, some volunteer surgeo...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-012-1548-z
更新日期:2012-10-01 00:00:00
abstract:PURPOSE:The platelet-to-lymphocyte ratio (PLR) has been extensively studied in various diseases. However, the relationship between PLR and hip fracture remains unknown. The aim of this study was to evaluate whether PLR would be an independent prognostic factor in elderly hip fracture patients. METHODS:Between January ...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-020-04833-1
更新日期:2021-01-01 00:00:00
abstract::The healing of flexor tendons was studied in chickens using transmission electron microscopy. After resecting the flexor sheath between the proximal and distal pulleys in zone II, the profundus tendon was severed and sutured. Intermittent passive motion was carried out 35 times daily immediately afterwards. The chicke...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/BF00189620
更新日期:1992-01-01 00:00:00
abstract:PURPOSE:Surgical treatment of an acute Achilles tendon rupture can effectively reduce the risk of re-rupture, but it increases the probability of surgical complications. We postulated that a minimally invasive surgical treatment might reduce the number of complications related to open surgery and improve the functional...
journal_title:International orthopaedics
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00264-012-1737-9
更新日期:2013-04-01 00:00:00
abstract::The patella clunk syndrome is not an uncommon complication, particularly after posterior-stabilized (PS) total knee arthroplasty. The present study was a consecutive unselected series comparing the incidence of the patella clunk syndrome amongst two comparable groups of elderly patients with knee arthritis implanted w...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-001-0316-2
更新日期:2002-01-01 00:00:00
abstract::We applied four published classifications for assessment of heterotopic ossification after total hip arthroplasty (Arcq, Brooker, DeLee and Della Valle [1, 2, 5, 6]. The average incidence of heterotopic ossification varied from 19.8% to 27.7%. The inter-observer reliability of the various classifications was determine...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-004-0603-9
更新日期:2005-06-01 00:00:00
abstract::Between 1991 and 2002, we treated 21 patients with tibial bone loss using a conventional external fixator. Nine patients had an infected open fracture and 12 patients an infected nonunion. After corticotomy, the bone was distracted at the rate of 1 mm (1 mm/step) on alternate days or every 48 h. The mean follow-up per...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-004-0553-2
更新日期:2004-06-01 00:00:00
abstract::Proliferating cell nuclear antigen (PCNA) is one of the cell cycle-related proteins directly involved in DNA synthesis. It is a marker of cellular proliferation and has been shown to correlate with ploidy and proliferative activity of cells. Its expression has been used to estimate the growth fraction of human cancer ...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s002640000147
更新日期:2000-01-01 00:00:00
abstract::We treated surgically 14 patients with symptomatic complete dislocation of the acromioclavicular joint. The surgical procedure included reconstruction of the coracoclavicular ligament using the coracoacromial ligament as substitute, reconstruction of the acromioclavicular ligament, and imbrications of the deltotrapezi...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-003-0520-3
更新日期:2004-04-01 00:00:00
abstract:PURPOSE:To investigate the effect of C3/4 disc degeneration on cervical spondylosis with dizziness (CSD) and to assess the curative effect of anterior cervical decompression and fusion (ACDF) in patients with CSD. METHOD:Four hundred nineteen patients who underwent ACDF for treatment of myelopathy or radiculopathy wer...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-020-04531-y
更新日期:2020-06-01 00:00:00
abstract:PURPOSE:Diabetes mellitus is associated with an increased risk of intervertebral disc degeneration (IDD). Reactive oxygen species (ROS), oxidative stressors, play a key role in autophagy of diabetes-associated diseases. Mitochondria are known to be the main source of endogenous ROS in most mammalian cell types. The aut...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-013-2037-8
更新日期:2013-12-01 00:00:00
abstract:BACKGROUND:Intramedullary calcaneal nailing is used to treat displaced intra-articular calcaneal fractures. The main goal of the study was to assess the reduction of tomography and secondary goals were patient functional scores and complication rates. METHODS:The functional outcome and restoration of the radiographic ...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-019-04381-3
更新日期:2019-12-01 00:00:00
abstract:PURPOSE:Our aim was to elucidate the pooled outcome of the CementLess Spotorno (CLS) system in total hip arthroplasty (THA). METHODS:We compared the outcome of clinical inventor studies, independent clinical studies, and worldwide register data. The main endpoints for analysis were revision rates. RESULTS:Twenty clin...
journal_title:International orthopaedics
pub_type: 杂志文章,meta分析
doi:10.1007/s00264-013-1867-8
更新日期:2013-06-01 00:00:00
abstract::We have reviewed the clinical features, together with the radiographs and computerised tomography, in 9 patients with tuberculosis of the vertebral body and neural arch. All presented with paraparesis or paraplegia. The morbidity associated with this disease is so serious that it is essential to have an accurate means...
journal_title:International orthopaedics
pub_type: 杂志文章,评审
doi:10.1007/BF00179971
更新日期:1995-01-01 00:00:00
abstract::As part of the international campaign of the bone and joint decade, we aimed to present epidemiological data on the prevalence of major joint complaints in a Central European region. Ten thousand subjects aged between 14 and 65, selected randomly by the Hungarian central office of statistics from three counties in sou...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-005-0033-3
更新日期:2006-04-01 00:00:00
abstract:PURPOSE:To assess histological changes and possible differences in the quadriceps of patients undergoing open repair of the tendon after spontaneous rupture, and subjects with no history of tendon pathology. MATERIALS:Biopsies were harvested from the quadriceps tendon of 46 patients (34 men, 12 women) who had reported...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-012-1637-z
更新日期:2012-11-01 00:00:00
abstract:PURPOSE:The aim of our study was to evaluate the effect of the S3 (spatial subchondral support) humeral plate and to compare the clinical outcomes and complications after ORIF (open reduction and internal fixation) of proximal humeral fractures using either a S3 plate or a PHLP (proximal humeral locking plate). METHOD...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-015-2705-y
更新日期:2015-06-01 00:00:00
abstract:PURPOSE:Extracorporeal shockwave therapy (ESWT) has become a common practice for treating knee osteoarthritis (OA). However, the effectiveness and safety of this treatment are still questionable. This meta-analysis is aimed at determining the degree of pain reduction and functional outcome after ESWT for knee OA. METH...
journal_title:International orthopaedics
pub_type: 杂志文章,评审
doi:10.1007/s00264-020-04489-x
更新日期:2020-05-01 00:00:00
abstract:PURPOSE:Relatively little is known about the extent to which periprosthetic joint infections (PJI) affect the patient's long-term quality of life (QoL). Our study aim was to assess the effect of a periprosthetic infection on our patients' QoL. METHODS:We collected data retrospectively of patients who had undergone sur...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-013-2265-y
更新日期:2014-05-01 00:00:00
abstract::We reviewed a consecutive series of 19 patients with comminuted periprosthetic fractures, loosening of the femoral stem (Vancouver type B3) and significant loss of bone stock (Paprosky type III and IV). Sixteen porous-coated long stems and three Exeter stems, all with impaction grafting, were used. Large femoral onlay...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-002-0423-8
更新日期:2003-01-01 00:00:00
abstract:PURPOSE:Restoring a neutral mechanical axis in total knee arthroplasty (TKA) (within ±3° of varus/valgus) is associated with superior functional outcome and reduced early implant failure. Using conventional alignment jigs results in malalignment in >20 % of cases. In this study, we investigated the reduction of outlier...
journal_title:International orthopaedics
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00264-014-2529-1
更新日期:2015-03-01 00:00:00
abstract::The aim of this non-randomised prospective study was to evaluate the short-term outcome of Gamma nail and dynamic hip screw (DHS) fixation in the treatment of subtrochanteric hip fractures due to low-energy trauma in the elderly. All of the 1,624 femoral hip fractures in 1,511 patients of the Oulu Hospital, aged over ...
journal_title:International orthopaedics
pub_type: 临床试验,杂志文章
doi:10.1007/s00264-006-0088-9
更新日期:2007-02-01 00:00:00
abstract:PURPOSE:This study was undertaken to prospectively analyse, at a mean five-year follow-up, the clinical, functional, and radiographic outcomes in patients who developed postoperative acute septic knee arthritis following anterior cruciate ligament (ACL) reconstruction using hamstring autograft. We also assessed the eff...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-013-2123-y
更新日期:2014-01-01 00:00:00
abstract::In order to clarify the association between mycotoxin-producing fungi in food and Kashin-Beck disease (KBD), we examined the occurrence and contamination levels of fungi in samples of barley grain, from KBD-affected families and from unaffected families in endemic areas. A control area without the occurrence of KBD se...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s002640000218
更新日期:2001-01-01 00:00:00
abstract::Twenty-one patients with patellar symptoms had arthroscopic treatment. Symptoms included frank patellar clunk and painful patellofemoral crepitus. All patients had posterior stabilized total knee replacement (TKR). The average onset of symptoms following TKR was 17 (range 3-75) months. All patients were referred to ph...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-002-0347-3
更新日期:2002-01-01 00:00:00
abstract:PURPOSE:The myofibroblast, a contractile fibroblastic cell expressing α-smooth muscle actin (α-SMA), has been reported to play a role in ligament healing. The aim of this study was to evaluate the feasibility of transplanting culture-derived myofibroblasts in injured rabbit medial collateral ligaments (MCL) and in inta...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-012-1519-4
更新日期:2012-08-01 00:00:00
abstract:PURPOSE:Endothelial dysfunction is a risk factor for osteonecrosis of femoral head (ONFH) and venous thromboembolism (VTE) [defined as deep venous thrombosis (DVT) or pulmonary embolism (PE)]. However, the risk of unprovoked VTE in non-traumatic ONFH patients remains unclear. METHODS:We investigated the relationship b...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-018-3866-2
更新日期:2018-07-01 00:00:00
abstract::The purpose of this study was to examine the effect of anabolic steroid hormones and exercise training on skeletal tendons. Female mice were exercised for 1 and 10 weeks in an endurance running programme on a treadmill. The altered ultrastructure of tendons caused by simultaneously administered anabolic steroid hormon...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/BF00266702
更新日期:1987-01-01 00:00:00
abstract::Fifty-four consecutive acute Achilles tendon ruptures were treated with end-to-end suture augmented with gastrocnemius fascial flaps. Surgery was performed within 24 h. Mean patient age was 35 (23-57) years, and 46 were men. Mean follow-up time was 4.8 (2-8) years. At follow-up, the mean visual analogue scale for pain...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-004-0598-2
更新日期:2005-02-01 00:00:00
abstract::Ten patients with clinical and radiological evidence of herniated discs at lower lumbar levels were treated with partial discectomy by a lateral percutaneous approach. Eight patients had complete relief from radicular pain and were discharged within four days. They returned to normal daily activity within one month. ...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/BF00271309
更新日期:1987-01-01 00:00:00