Myeloperoxidase-antineutrophil cytoplasmic antibody (ANCA)-associated systemic vasculitis developed from ANCA negative renal limited vasculitis: A case report.

Abstract:

RATIONALE:The relationship between antineutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (AAV) and ANCA-negative vasculitis has not been elucidated. PATIENT CONCERNS:A 64-year-old female with edema and proteinuria was admitted. A kidney biopsy indicated focal proliferative nephritis with crescents in 25% of glomeruli. Serum ANCA was negative. Eighteen months later, systemic symptoms emerged and acute kidney injury occurred. Serum ANCA against myeloperoxidase (MPO) turned positive. Repeated kidney biopsy showed more severe lesion than last time. Immunoglobulin (Ig)G was purified from serum obtained before the first kidney biopsy. Weak ANCA which could not be detected in serum was found in IgG. DIAGNOSES:MPO-ANCA-associated AAV developed from ANCA-negative renal-limited AAV. INTERVENTIONS:The patient was treated with glucocorticoid. OUTCOMES:The serum creatinine decreased to 2.17 mg/dL a week later. MPO-ANCA turned negative when re-examined 3 weeks later. No relapse has been observed during follow-up for 6 months. LESSONS:This is the first reported case about the spontaneous transformation from ANCA-negative renal-limited AAV to ANCA-positive systemic vasculitis. There might be a slow process of epitope spreading in the pathogenesis of disease. Physicians should try their best to detect the ANCA in the diagnose and treatment of ANCA-negative AAV.

journal_name

Medicine (Baltimore)

journal_title

Medicine

authors

Li XL,Xu PC,Chen T,Yan TK,Jiang JQ,Jia JY,Wei L,Shang WY,Hu SY

doi

10.1097/MD.0000000000009128

subject

Has Abstract

pub_date

2017-12-01 00:00:00

pages

e9128

issue

51

eissn

0025-7974

issn

1536-5964

pii

00005792-201712220-00027

journal_volume

96

pub_type

杂志文章

相关文献

MEDICINE文献大全
  • Metastatic epithelioid trophoblastic tumor of the lung: A case report.

    abstract:RATIONALE:Epithelioid trophoblastic tumor (ETT) is a very rare form of gestational trophoblastic disease (GTD) which arises from neoplastic proliferation of intermediate trophoblasts. Metastatic ETT of the lung is extremely rare in postmenopausal women. PATIENT CONCERNS:Here we describe a 50-year-old woman with a meta...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000010306

    authors: Lei W,Zhang F,Zheng C,Zhao C,Tu S,Bao Y

    更新日期:2018-04-01 00:00:00

  • Prevalence and Predictive Factors of Chronic Postsurgical Pain and Global Surgical Recovery 1 Year After Outpatient Knee Arthroscopy: A Prospective Cohort Study.

    abstract::Outpatient knee arthroscopy is one of the most commonly performed surgical procedures. Previous research has demonstrated that chronic postsurgical pain (CPSP) after outpatient surgery is prevalent. Our objective was to determine the prevalence and predictive factors of CPSP and Global Surgical Recovery (GSR) 1 year a...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000002017

    authors: Hoofwijk DMN,Fiddelers AAA,Emans PJ,Joosten EA,Gramke HF,Marcus MAE,Buhre WFFA

    更新日期:2015-11-01 00:00:00

  • Predictive value of soluble ST-2 for changes of cardiac function and structure in breast cancer patients receiving chemotherapy.

    abstract::The current study was to evaluate soluble ST-2 level and left ventricular ejection fraction (LVEF) in patients with breast cancer receiving doxorubicin or trastuzumab treatment for 6 months and determine whether soluble ST-2 level can be used to predictive left ventricular function impairment.Patients who were diagnos...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000012447

    authors: Huang G,Zhai J,Huang X,Zheng D

    更新日期:2018-09-01 00:00:00

  • Anthropometric and Quality-of-Life Parameters in Acute Intermittent Porphyria Patients.

    abstract::The porphyrias are a group of rare metabolic disorders. The incidence and prevalence are low because the acute intermittent porphyria (AIP) is rare. Our aim was to assess the use of anthropometric and quality-of-life parameters in porphyric patients in order to identify predictor factors that might help in characteriz...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000001023

    authors: Jiménez-Monreal AM,Murcia M,Gómez-Murcia V,Bibiloni MDM,Pons A,Tur JA,Martínez-Tomé M

    更新日期:2015-07-01 00:00:00

  • Meta-analysis of correlationship between HLA-G 3'UTR 14-bp Ins/Del polymorphism and virus susceptibility.

    abstract:BACKGROUND:There is a considerable amount of literature on the potential relationship between human leukocyte antigen-G 14-bp Ins/Del polymorphism and virus infection; however, results from these studies were inconclusive. OBJECTIVES:A meta-analysis was carried out to determine whether the 14-bp Ins/Del polymorphism i...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000012262

    authors: Lv H,Lv H,Lin Z,Chen L,Zhu M,Hong D

    更新日期:2018-09-01 00:00:00

  • Molecular profiling of the colon cancer in South-Eastern Romania: Results from the MERCUR study.

    abstract:ABSTRACT:Colorectal cancer is a heterogeneous disease with multiple epigenetic alterations and different molecular features. The molecular classification is based on 2 major distinct pathways: microsatellite stable pathway and the microsatellite instability pathway. Molecular profiling of colorectal cancer provides imp...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000024062

    authors: Popescu RC,Tocia C,Brînzan C,Cozaru GC,Deacu M,Dumitru A,Leopa N,Mitroi AF,Nicolau A,Dumitru E

    更新日期:2021-01-08 00:00:00

  • Pathologic femoral fracture due to tenofovir-induced Fanconi syndrome in patient with chronic hepatitis B: A case report.

    abstract:RATIONALE:We report a case of a hepatitis B virus (HBV)-positive patient with preexisting bone disease who developed tenofovir-induced Fanconi syndrome and subsequently sustained pathologic fracture. To our best knowledge, this is the first report in the English literature about pathologic femoral fracture due to tenof...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000008760

    authors: Suh YS,Chun DI,Choi SW,Lee HW,Nho JH,Kwon SH,Cho JH,Won SH

    更新日期:2017-11-01 00:00:00

  • Genetically determined ancestry is more informative than self-reported race in HIV-infected and -exposed children.

    abstract::The Pediatric HIV/AIDS Cohort Study (PHACS), the largest ongoing longitudinal study of perinatal HIV-infected (PHIV) and HIV-exposed, uninfected (PHEU) children in the United States, comprises the Surveillance Monitoring of Antiretroviral Therapy [ART] Toxicities (SMARTT) Study in PHEU children and the Adolescent Mast...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000004733

    authors: Spector SA,Brummel SS,Nievergelt CM,Maihofer AX,Singh KK,Purswani MU,Williams PL,Hazra R,Van Dyke R,Seage GR 3rd,Pediatric HIV\/AIDS Cohort Study (PHACS).

    更新日期:2016-09-01 00:00:00

  • Isoniazid preventive therapy in HIV-infected pregnant and postpartum women in high prevalence of tuberculosis countries: A protocol for systematic review.

    abstract:BACKGROUND:Tuberculosis (TB) is the leading cause of health complications and death among human with immunodeficiency virus (HIV) infection. When TB develops during pregnancy or the early postpartum period, it is associated with negative maternal, pregnancy, and fetus and infant outcome, including premature birth, low ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000023089

    authors: Wang X,Zhang Y,Lin X,Fu Y,Sun Q,Li J,Liu X,Bai J

    更新日期:2020-11-20 00:00:00

  • Association of increased B7 protein expression by infiltrating immune cells with progression of gastric carcinogenesis.

    abstract::B7 negative costimulatory molecules are a group of molecules associated with the occurrence, development, and therapy of cancers. Here, we aimed to determine the clinical significance of PD-L1, B7-H3, and B7-H4 and their expression in CD8 and CD68 positive cells at different stages of gastric carcinogenesis.We detecte...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000014663

    authors: Guo L,Liu Z,Zhang Y,Quan Q,Huang L,Xu Y,Cao L,Zhang X

    更新日期:2019-02-01 00:00:00

  • Top 100 cited articles on infection in orthopaedics: A bibliometric analysis.

    abstract:PURPOSE:The infection is an essential problem in the clinical practice in orthopedics. The bibliometric analysis was conducted to evaluate the top 100 cited articles on infection in orthopaedics. METHODS:The Web of Science (WoS) Core Database was comprehensively searched from 1975 to 2017, and the literature search wa...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000014067

    authors: Jiang Y,Hu R,Zhu G

    更新日期:2019-01-01 00:00:00

  • 11C-acetate and 18F-fluorodeoxyglucose positron emission tomography/computed tomography dual imaging for the prediction of response and prognosis after transarterial chemoembolization.

    abstract::The aim of the present study was to evaluate the clinical significance of dual radiotracer studies, C-acetate and F-fluoro-D-glucose positron emission tomography/computed tomography (F-FDG PET/CT), for the prediction of response and recurrence after transarterial chemoembolization (TACE).This study retrospectively inc...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000012311

    authors: Park S,Kim TS,Kang SH,Kim HB,Park JW,Kim SK

    更新日期:2018-09-01 00:00:00

  • Patterns of lymph node metastasis in locally advanced cervical cancer.

    abstract::The aim of this study was to investigate patterns and locations of lymph node metastasis in locally advanced cervical cancers.A total of 244 consecutive patients with stage IIb cervical cancer were retrospectively evaluated. Contrast-enhanced CT scans were used for lymph node grading. Lymph nodes with the shortest axi...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000004814

    authors: Liu Z,Hu K,Liu A,Shen J,Hou X,Lian X,Sun S,Yan J,Zhang F

    更新日期:2016-09-01 00:00:00

  • Diagnostic accuracy of pediatric atypical appendicitis: Three case reports.

    abstract:RATIONALE:Acute appendicitis is one of the most common causes of acute abdomen in children, yet it is difficult to diagnose in young children because its clinical manifestations may be atypical. Here, 3 atypical clinical cases associated with appendicitis in children are reported. PATIENT CONCERN:The 1st case correspo...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000015006

    authors: Wang ZH,Ye J,Wang YS,Liu Y

    更新日期:2019-03-01 00:00:00

  • The changing modes of human immunodeficiency virus transmission and spatial variations among women in a minority prefecture in southwest China: An exploratory study.

    abstract::Liangshan Yi Autonomous Prefecture in Southwest China has a high human immunodeficiency virus (HIV) prevalence rate. This study examined the changing modes of HIV transmission among women with new HIV infections and explored the spatial heterogeneities in the factors associated with heterosexual transmission in this m...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000018776

    authors: Xiao C,Jike C,Liu D,Jia P,Xu X,Xiao L,Yu G,Nan L,Sun X,Ge J,Wang J,Wang K,Liao Q,Wang Q,Wenwen Z,Yang S

    更新日期:2020-02-01 00:00:00

  • Medical Comics as Tools to Aid in Obtaining Informed Consent for Stroke Care.

    abstract::Informed consent has now become common in medical practice. However, a gap still exists between doctors and patients in the understanding of clinical conditions. We designed medical comics about "subarachnoid hemorrhage" and "intracerebral hemorrhage" to help doctors obtain informed consent intuitively, quickly, and c...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000001077

    authors: Furuno Y,Sasajima H

    更新日期:2015-07-01 00:00:00

  • The effect of sex hormones on normal breast tissue metabolism: Evaluation by FDG PET/CT.

    abstract::This study investigated the effect of sex hormones on F-fluorodeoxyglucose (FDG) uptake in normal breast tissue.The retrospective study included 249 premenopausal women (median age, 45 years) who were diagnosed with unilateral breast cancer and underwent FDG positron emission tomography/computed tomography and hormone...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000016306

    authors: Jung Y,Kim TH,Kim JY,Han S,An YS

    更新日期:2019-07-01 00:00:00

  • Bee venom acupuncture for adhesive capsulitis: A protocol for systematic review and meta-analysis.

    abstract:BACKGROUND:Bee venom acupuncture has been used in treating patients with shoulder adhesive capsulitis, yet the effectiveness and safety remains unclear. Therefore, this systematic review will aim to assess the effectiveness and safety of bee venom acupuncture for shoulder adhesive capsulitis. METHODS:Electronic databa...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000019975

    authors: Chen X,Fan H,Chen J,Fan H,Wu P

    更新日期:2020-05-01 00:00:00

  • Genetic Characteristics of CRF01_AE Among Newly Diagnosed HIV-1-Infected 16- to 25-Year Olds in 3 Geographic Regions of Guangxi, China.

    abstract::The aim of this study was to analyze the distribution of clusters and drug resistance of CRF01_AE among newly diagnosed, treatment-naïve HIV-infected teenagers and young adults in 3 major HIV-affected geographic regions of Guangxi Province, including the cities of Hezhou, Liuzhou, and Nanning. Samples were sequentiall...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000000894

    authors: Zhang J,Shen ZY,Li Z,Liang SJ,He C,Liang FX,Feng Y,Li JJ,Ruan YH,Zhou YJ,Shao YM,Xing H,Liao LJ

    更新日期:2015-05-01 00:00:00

  • Association Between the MUC5B Promoter Polymorphism rs35705950 and Idiopathic Pulmonary Fibrosis: A Meta-analysis and Trial Sequential Analysis in Caucasian and Asian Populations.

    abstract::Idiopathic pulmonary fibrosis (IPF) is a progressive disease with a poor prognosis. A number of studies reported the association between MUC5B promoter polymorphism rs35705950 and IPF, but substantial inconsistent findings were observed and the strength of association remains unclear.The aim of the study was to invest...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000001901

    authors: Zhu QQ,Zhang XL,Zhang SM,Tang SW,Min HY,Yi L,Xu B,Song Y

    更新日期:2015-10-01 00:00:00

  • Association between early Helicobacter pylori eradication and a lower risk of recurrent complicated peptic ulcers in end-stage renal disease patients.

    abstract::End-stage renal disease (ESRD) patients exhibit an increased incidence of peptic ulcer disease. Helicobacter pylori plays a central role in the development of peptic ulcers. The effect of early H pylori eradication on the recurrence of complicated peptic ulcer disease in ESRD patients remains unclear. The aim of the p...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000000370

    authors: Chang SS,Hu HY

    更新日期:2015-01-01 00:00:00

  • Trend and survival outcome in Taiwan cervical cancer patients: A population-based study.

    abstract::Cervical cancer is one of the most common cancers in Taiwan. The aim of this study was to estimate the incidence of cervical cancer in Taiwan, the relationship between cervical cancer and previous co-morbidities, and the long-term trend of cervical cancer mortality differences in the rest of the world.This study was b...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000014848

    authors: Kau YC,Liu FC,Kuo CF,Huang HJ,Li AH,Hsieh MY,Yu HP

    更新日期:2019-03-01 00:00:00

  • Successful percutaneous stent implantation for isolated dismal transverse aortic arch kinking.

    abstract:RATIONALE:Isolated dismal transverse aortic arch kinking in adults is rare, and there is no recommended therapy at present. Percutaneous stent implantation may be an effective method to correct it and could be considered. PATIENT CONCERNS:We report a 46-year-old woman who suffered from recurrent migraine and refractor...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000006089

    authors: Zuo ZL,Tsauo JY,Chen M,Feng Y

    更新日期:2017-03-01 00:00:00

  • Subaortic stenosis revisited: the importance of the dynamic pressure gradient.

    abstract::Brachfeld and Gorlin's revised concept of subaortic stenosis derived from their recognition that the large magnitudes of the pressure gradients were incompatible with the relatively mild anatomic lesions found at surgery in 3 of their patients, and the rapidity of their arterial pulse upstroke. They proposed that a gr...

    journal_title:Medicine

    pub_type: 传,评论,历史文章,杂志文章

    doi:

    authors: Criley JM,Siegel RJ

    更新日期:1993-11-01 00:00:00

  • The high prevalence of subclinical atherosclerosis in patients with ankylosing spondylitis without clinically evident cardiovascular disease.

    abstract::We conducted the present study to determine whether subclinical macrovascular atherosclerotic disease was present in patients with ankylosing spondylitis (AS) without clinical history of cardiovascular disease. We also sought to establish whether demographic or clinical features of the disease may influence the develo...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0b013e3181c10773

    authors: Gonzalez-Juanatey C,Vazquez-Rodriguez TR,Miranda-Filloy JA,Dierssen T,Vaqueiro I,Blanco R,Martin J,Llorca J,Gonzalez-Gay MA

    更新日期:2009-11-01 00:00:00

  • National incidence of traumatic spinal fractures in China: Data from China National Fracture Study.

    abstract::To provide a basis for disease prevention, this article aimed to clarify the incidence and risk factors of traumatic fractures in China.The China National Fracture Study (CNFS) was a retrospective epidemiological study that recruited a nationally representative sample from 8 provinces, 24 urban cities, and 24 rural co...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000012190

    authors: Liu B,Zhu Y,Liu S,Chen W,Zhang F,Zhang Y

    更新日期:2018-08-01 00:00:00

  • Usefulness of voxel-based lesion mapping for predicting motor recovery in subjects with basal ganglia hemorrhage: A preliminary study with 2 case reports.

    abstract::It is important to estimate motor recovery in the early phase after stroke. Many studies have demonstrated that both diffusion tensor tractography (DTT) and motor-evoked potentials (MEP) are valuable predictors of motor recovery, but these modalities do not directly reflect the status of the injured gray matter. We re...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000003838

    authors: Kim DH,Kyeong S,Cho Y,Jung TM,Ahn SJ,Park YG

    更新日期:2016-06-01 00:00:00

  • Total parathyroidectomy plus multi-point subcutaneous transplantation in the forearm may be a reliable surgical approach for patients with end-stage renal disease: A case report.

    abstract:RATIONALE:We studied the feasibility of total arathyroidectomy(tPTX)+multi-point transplantation in the forearm for treatment of secondary hyperparathyroidism. Considering the controversial nature of the appropriate timing for and location of this type of surgery, relevant research is relatively rare. Our experience ma...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000017649

    authors: Lin N,Fang YC,Song JC,Wang Y

    更新日期:2019-11-01 00:00:00

  • Epidemiology and clinical characteristics of traumatic brain injury in Lebanon: A systematic review.

    abstract:BACKGROUND:Traumatic brain injury (TBI) is a debilitating medical and emerging public health problem that is affecting people worldwide due to a multitude of factors including both domestic and war-related acts. The objective of this paper is to systematically review the status of TBI in Lebanon - a Middle Eastern coun...

    journal_title:Medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MD.0000000000005342

    authors: Abou-Abbass H,Bahmad H,Ghandour H,Fares J,Wazzi-Mkahal R,Yacoub B,Darwish H,Mondello S,Harati H,El Sayed MJ,Tamim H,Kobeissy F

    更新日期:2016-11-01 00:00:00

  • Unmet challenges in treating hypertension in patients with borderline personality disorder: A systematic review.

    abstract:BACKGROUND:Caregivers encounter serious and substantial challenges in managing hypertension in patients with subclinical or clinical borderline personality disorder (BPD). These challenges include therapeutic conflicts resulting from harmful drug-drug, and drug-disease interactions. Current guidelines provide no recomm...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000017101

    authors: Roininen SM,Cheetham M,Mueller BU,Battegay E

    更新日期:2019-09-01 00:00:00