An overview of pharmacotherapy for bipolar I disorder.

abstract：OBJECTIVE:Injection diclofenac sodium available at present as a 3-ml formulation is administered intragluteally. Standard needles may not reach the gluteus maximus muscle in many cases, especially in obese patients. Alternative sites like the deltoid have been suggested to be more suitable for these patients. Diclofena...

journal_title：Expert opinion on pharmacotherapy

authors： Ojha A,Shep D,Nivsarkar M,Patel S,Jaiswal V,Padh H

更新日期：2009-03-01 00:00:00

abstract：INTRODUCTION:Breast cancer (BC) remains the most frequently diagnosed cancer and the most common cause of cancer death among women of all races worldwide. Over 80% of BC cases are hormone receptor (HR)-positive, comprised of luminal A and luminal B per molecular subtypes, imposing an urgent need to fully understand the...

journal_title：Expert opinion on pharmacotherapy

authors： Duso BA,Trapani D,Viale G,Criscitiello C,D'Amico P,Belli C,Mazzarella L,Locatelli M,Minchella I,Curigliano G

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Prescription omega-3-acid ethyl esters (P-OM3) have been used as adjunctive therapy to statin drugs in patients with mixed hyperlipidemia. OBJECTIVE:To assess the effect of concomitant administration of 4 g P-OM3 on the steady-state pharmacokinetics of the maximum recommended daily dose of atorvastatin (80 ...

journal_title：Expert opinion on pharmacotherapy

authors： Di Spirito M,Morelli G,Doyle RT,Johnson J,McKenney J

更新日期：2008-12-01 00:00:00

abstract：INTRODUCTION:Hydrochlorothiazide (HCTZ) has not been shown to reduce mortality or cardiovascular events when given as a single agent. In fact, HCTZ increased cardiovascular death and coronary artery disease (CAD) compared to placebo and usual care in 2 randomized trials, yet it is the most prescribed diuretic in the Un...

journal_title：Expert opinion on pharmacotherapy

authors： DiNicolantonio JJ

更新日期：2012-04-01 00:00:00

abstract：:Migraine is a multifactorial and disabling syndrome often in comorbidity with psychiatric illnesses. Triptans are the first-line treatment in acute attacks and the most effective drugs in various types of migraine. Sumatriptan was the first medication of this group. Thanks to multiple types of formulations that greatl...

journal_title：Expert opinion on pharmacotherapy

authors： Napoletano F,Lionetto L,Martelletti P

更新日期：2014-02-01 00:00:00

abstract：INTRODUCTION:Short bowel syndrome (SBS) has traditionally been regarded as a rapidly fatal medical catastrophe. The advent of pharmacological options directly targeting disease pathophysiology justified this review. AREAS COVERED:Since the 1970s, home parenteral nutrition has reduced mortality, converting SBS into a c...

journal_title：Expert opinion on pharmacotherapy

authors： Hollanda Martins Da Rocha M,Lee ADW,Marin MLM,Faintuch S,Mishaly A,Faintuch J

更新日期：2020-04-01 00:00:00

abstract：INTRODUCTION:Complicated intraabdominal infections (cIAIs) are a common cause of infection-related morbidity and mortality in hospitalized patients and present many challenges unique from other serious infections. cIAIs are generally polymicrobial in nature; however, controversy exists around the pathogenicity of some ...

journal_title：Expert opinion on pharmacotherapy

authors： Skrupky LP,Tellor BR,Mazuski JE

更新日期：2013-10-01 00:00:00

abstract：INTRODUCTION:BRAF inhibition alone has achieved unprecedented efficacy results in patients affected by BRAF-mutated advanced melanoma. Since these findings, it was postulated that dual inhibition of BRAF and other components of the RAS/RAF/MEK/ERK MAPK pathway (such as MEK) would be superior to BRAF inhibition as monot...

journal_title：Expert opinion on pharmacotherapy

authors： Richman J,Martin-Liberal J,Diem S,Larkin J

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Miconazole nitrate is a time-honored antifungal of the imidazole class. OBJECTIVE:To revisit the various aspects of action of the drug in a dermatologic setting. METHOD:Review of the current peer-reviewed publications. RESULTS/CONCLUSION:Miconazole essentially inhibits 14alpha-demethylase, an enzyme requi...

journal_title：Expert opinion on pharmacotherapy

authors： Quatresooz P,Vroome V,Borgers M,Cauwenbergh G,Piérard GE

更新日期：2008-08-01 00:00:00

abstract：:New approved options with opioids in the postoperative setting may include new ways of administration, new combinations with other drugs and new opioid drugs. Newly approved devices for administration include sublingual sufentanil dispenser and transdermal iontophoretic fentanyl, with the purpose of almost mimicking t...

journal_title：Expert opinion on pharmacotherapy

authors： Raeder J

更新日期：2014-03-01 00:00:00

abstract：:The International Continence Society has defined overactive bladder (OAB) as urinary urgency, with or without urge urinary incontinence, usually with urinary frequency and nocturia. Approximately 17% of men and women in the US report OAB symptoms, which can affect quality of life. Trospium chloride, which has recently...

journal_title：Expert opinion on pharmacotherapy

authors： Zinner NR

更新日期：2005-07-01 00:00:00

abstract：INTRODUCTION:Antipsychotic drugs are increasingly used in the maintenance treatment of bipolar disorder. This review addresses the evidence supporting the use of one of these medications for this indication in order to place available data in perspective for the clinician. AREAS COVERED:The approval of ziprasidone for...

journal_title：Expert opinion on pharmacotherapy

authors： Dubovsky SL,Dubovsky AN

更新日期：2011-04-01 00:00:00

abstract：:The introduction of anti-TNFalpha therapy into the field of rheumatology has led to dramatic improvements in patient care, perhaps the most remarkable being in the management of ankylosing spondylitis. As experience with these compounds grows, their place in therapeutic strategy is becoming clearer, and it has been po...

journal_title：Expert opinion on pharmacotherapy

authors： Zochling J,Braun J

更新日期：2006-05-01 00:00:00

abstract：INTRODUCTION:Much research has gone into developing medications that can be used to alleviate endometriosis-associated symptoms. In addition to already established medications, a new GnRH antagonist, elagolix, is in development. The novelty of this drug compared to other GnRH antagonists, is its nonpeptide structure, a...

journal_title：Expert opinion on pharmacotherapy

authors： Perricos A,Wenzl R

更新日期：2017-09-01 00:00:00

abstract：INTRODUCTION:Overactive bladder (OAB) is a common condition that has a profound impact on an individual's overall health and quality of life. Muscarinic receptor antagonists are the mainstay of oral pharmacotherapy for OAB. While all of the medications in this class are significantly more effective than placebo, they a...

journal_title：Expert opinion on pharmacotherapy

authors： Gomelsky A,Dmochowski RR

更新日期：2012-06-01 00:00:00

abstract：:ABSTARCT Introduction: Cardiovascular disease (CVD) continues to be an essential cause of morbidity and mortality among people living with human immunodeficiency virus infection (PLWH). Since the bulk of cardiovascular risk (CVR) factors are shared between PLWH and the general population, prevention and treatment stra...

journal_title：Expert opinion on pharmacotherapy

authors： Corbacho N,Mur I,Molas ME,Vidal F,Domingo P

更新日期：2021-01-04 00:00:00

abstract：:Oseltamivir is the ethyl ester prodrug of the antiviral molecule, oseltamivir carboxylate, a potent and selective inhibitor of influenza A and B neuraminidase (NA) (sialidase). It is highly bioavailable in capsule and suspension formulations and, after conversion to the active metabolite in the liver, distributes thro...

journal_title：Expert opinion on pharmacotherapy

authors： Doucette KE,Aoki FY

更新日期：2001-10-01 00:00:00

abstract：IMPORTANCE OF THE FIELD:Mifepristone is a synthetic selective progesterone-receptor modulator (SPRM) that is widely used around the globe in the field of reproductive medicine. At present mifepristone is approved in a number of countries for early termination of pregnancy (TOP), cervical dilatation before surgical TOP,...

journal_title：Expert opinion on pharmacotherapy

authors： Im A,Appleman LJ

更新日期：2010-02-01 00:00:00

abstract：:Chronic refractory angina is a term used to describe patients who, despite optimal medical therapy, have both angina and objective evidence of ischaemia. It is estimated that 5-15% of the 12 million patients with chronic angina in the US meet the criteria for having refractory angina. This review focuses on the follow...

journal_title：Expert opinion on pharmacotherapy

authors： Yang EH,Barsness GW

更新日期：2006-02-01 00:00:00

abstract：INTRODUCTION:The introduction of novel agents has significantly improved multiple myeloma (MM) patient outcome during the last two decades. MM received the most drug approvals for any one malignancy during this time period, both in the United States as well as in Europe. Areas covered: Proteasome inhibitors, immunomodu...

journal_title：Expert opinion on pharmacotherapy

authors： Podar K,Pecherstorfer M

更新日期：2017-08-01 00:00:00

abstract：:Introduction: Liposarcomas are a heterogeneous group of soft tissue tumors that arise from adipose tissue and are one of the most common soft tissue sarcomas found in adults. Liposarcomas are subclassified into four subtypes with distinct histologic and biologic features that influence their treatment and management. ...

journal_title：Expert opinion on pharmacotherapy

authors： Suarez-Kelly LP,Baldi GG,Gronchi A

更新日期：2019-08-01 00:00:00

abstract：INTRODUCTION:Peripheral artery disease (PAD) is a prevalent but underdiagnosed manifestation of atherosclerosis that has a worse prognosis than coronary artery disease. Patients with PAD are at heightened risk of both systemic cardiovascular adverse events and limb-related morbidity. There is insufficient awareness of ...

journal_title：Expert opinion on pharmacotherapy

authors： Essa H,Torella F,Lip GYH

更新日期：2020-09-01 00:00:00

abstract：INTRODUCTION:Non-small cell lung cancer (NSCLC) is a major cause of cancer-related death worldwide. Although advanced NSCLC is still incurable, various anti-neoplastic agents have become available for the treatment of this disease. Pemetrexed , a multi-target folate antagonist, has improved the survival of non-squamous...

journal_title：Expert opinion on pharmacotherapy

authors： Genova C,Rijavec E,Truini A,Coco S,Sini C,Barletta G,Dal Bello MG,Alama A,Savarino G,Pronzato P,Boccardo F,Grossi F

更新日期：2013-08-01 00:00:00

abstract：INTRODUCTION:Asthma is the most common chronic disease in childhood, affecting approximately 10% of all children, and is the leading cause of hospitalization in developed countries. In this paper we aimed to review the evidence on chemical pharmacotherapy for long-term treatment of pediatric asthma, according to the la...

journal_title：Expert opinion on pharmacotherapy

authors： Vitale C,Maglio A,Pelaia C,Vatrella A

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Obesity has become a global epidemic with recent estimates of > 400 million obese adults. Despite this, there are few safe and effective pharmacological interventions for obesity. Sibutramine is a weight loss agent, for use as an adjuvant to a comprehensive program of calorie restriction, exercise and behavi...

journal_title：Expert opinion on pharmacotherapy

authors： Sharma B,Henderson DC

更新日期：2008-08-01 00:00:00

abstract：:This paper describes the functional roles of the closely related pharmacogenetic and pharmacogenomic sciences in medicine. Firstly, they provide means for a better understanding of the function of drugs, and particularly of the differences of drug action between individuals and also between racially categorised popula...

journal_title：Expert opinion on pharmacotherapy

authors： Kalow W

更新日期：2005-07-01 00:00:00

abstract：INTRODUCTION:The potency, tolerability and convenience of antiretroviral agents have all significantly improved over the past years, making lifelong HIV therapy easier. However, several specific needs are still unmet, including low daily pill burden, friendly metabolic profile, lack of (or few) drug interactions and hi...

journal_title：Expert opinion on pharmacotherapy

authors： Fernández-Montero JV,Vispo E,Soriano V

更新日期：2014-02-01 00:00:00

abstract：INTRODUCTION:Postprandial hyperglycemia (PPHG) contributes to micro- and macro-vascular complications more than fasting hyperglycemia in patients with type 2 diabetes mellitus. Due to the traditional carbohydrate-rich diet, Asians, particularly Indians and Chinese need agents to control the higher risk of uncontrolled ...

journal_title：Expert opinion on pharmacotherapy

authors： Joshi SR,Standl E,Tong N,Shah P,Kalra S,Rathod R

更新日期：2015-01-01 00:00:00

abstract：INTRODUCTION:Chronic spontaneous urticaria (CSU) refers to urticaria (wheals) or angioedema, which occur for a period of six weeks or longer without an apparent cause. The condition may impair the patient's quality of life. AREAS COVERED:Treatment for CSU is mainly symptomatic. Both AAAAI/ACAAI practice parameters and...

journal_title：Expert opinion on pharmacotherapy

authors： Hon KL,Li JTS,Leung AKC,Lee V

更新日期：2020-09-29 00:00:00

abstract：:Peglyated liposomal doxorubicin was developed to maintain or enhance the demonstrated antineoplastic effects of doxorubicin, while improving the toxicity profile associated with this important cytotoxic agent. Accumulating clinical data have confirmed the activity of pegylated liposomal doxorubicin in cancers of the b...

journal_title：Expert opinion on pharmacotherapy

authors： Markman M

更新日期：2006-08-01 00:00:00