Abstract:
:Contrast response functions (CRFs) from multifocal visual-evoked potential (mfVEP) and BOLD fMRI responses were obtained using the same stimuli to test the hypothesis of a linear relationship between the mfVEP and BOLD fMRI responses. Monocular mfVEP and BOLD fMRI responses were obtained using an 8 degrees in diameter, dartboard pattern stimulus with reversing checkerboards. Six contrast conditions (4%, 8%, 16%, 32%, 64%, and 90%) were run. The mfVEP, largely generated in V1, was compared to the BOLD fMRI signal from V1 and extrastriate cortex. Retinotopic maps of each subject were acquired and used to localize the V1 area. For all subjects, the CRFs for the mfVEPs and BOLD fMRI responses showed good agreement, suggesting that they both share the same functional relationship with underlying neural activity. In particular, this result is consistent with the assumption that the relationship between the BOLD response and underlying neural activity is linear, although the particular linear model proposed by D. J. Heeger, A. C. Huk, W. S. Geisler, and D. G. Albrecht (2000) does not fit the results.
journal_name
J Visjournal_title
Journal of visionauthors
Park JC,Zhang X,Ferrera J,Hirsch J,Hood DCdoi
10.1167/8.10.8subject
Has Abstractpub_date
2008-10-22 00:00:00pages
8.1-12issue
10issn
1534-7362pii
8/10/8journal_volume
8pub_type
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journal_title:Journal of vision
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journal_title:Journal of vision
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