[Treatment with sublingual desmopressin in two infants with hydranencephaly and central diabetes insipidus].

Abstract:

:Central diabetes insipidus is a rare disease in children caused by a deficiency of vasopressin. Its main clinical manifestations are polyuria and polydipsia. Brain malformations are one of the main causes. Desmopressin is the synthetic drug of choice for the treatment. One of the routes of administration is sublingual and its use in infants is very limited. We describe two infants with central diabetes insipidus and hydranencephaly who were successfully treated with sublingual desmopressin. :La diabetes insípida central es una patología infrecuente en pediatría ocasionada por un déficit de vasopresina. Sus manifestaciones clínicas principales son poliuria y polidipsia. Las malformaciones cerebrales son una de las principales causas. La desmopresina es la droga sintética de elección para el tratamiento. Una de las vías de administración es la sublingual y su uso en lactantes es muy limitado. Se describe a dos lactantes con hidranencefalia y diabetes insípida central que fueron tratados satisfactoriamente con desmopresina sublingual.

journal_name

Arch Argent Pediatr

authors

Marín GR,Baspineiro B,Vilca I

doi

10.5546/aap.2018.e93

subject

Has Abstract

pub_date

2018-02-01 00:00:00

pages

e93-e97

issue

1

eissn

0325-0075

issn

1668-3501

journal_volume

116

pub_type

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