Abstract：
:'Significant' objects contribute greatly to scene recognition. The lateral occipital complex (LOC), parahippocampal place area (PPA), and retrosplenial cortex (RSC) play a crucial role in the cognitive processing of objects and scenes. However, the associated mechanism between objects and scenes remains unclear. In this study, four categories of scene images and four types of significant objects were designed as stimuli. Representational similarity analysis (RSA) of functional magnetic resonance imaging (fMRI) data showed that correlation coefficients of the activity patterns for objects and scenes were significantly positive in the LOC and PPA. Compared to the out-of-scene objects, the correlation strengths for within-scene objects were significantly greater in the PPA and two subregions of the LOC: the lateral occipital area (LO), and posterior fusiform area (PF). Further correlation analyses showed that the scene-object correlations were different for indoor and outdoor scenes in the LO, pF and PPA. Semantic associations were represented in the LO and pF, while the PPA was involved in semantic correlations and spatial characteristics, which were sensitive to the openness of scenes. However, these trends were not observed in the RSC, suggesting that it is not recruited to process semantic associations between scenes and objects. Our findings provide an understanding of the neural mechanism of scene recognition.
journal_name
Neurosciencejournal_title
Neuroscienceauthors
Wang S,Cao L,Xu J,Zhang G,Lou Y,Liu Bdoi
10.1016/j.neuroscience.2017.12.043subject
Has Abstractpub_date
2018-02-21 00:00:00pages
87-96eissn
0306-4522issn
1873-7544pii
S0306-4522(17)30933-8journal_volume
372pub_type
杂志文章相关文献
NEUROSCIENCE文献大全abstract：:The role of Orphanin-FQ/nociceptin in synaptic plasticity was assessed by its potency in modulating kindling epileptogenesis in vivo, and feed-forward inhibition in hippocampal recordings in vitro. In addition, a specific rabbit antiserum against this peptide was obtained and the immunohistochemical distribution of no...
journal_title：Neuroscience
pub_type： 杂志文章
doi：10.1016/s0306-4522(01)00196-8
更新日期：2001-01-01 00:00:00
abstract：:The involvement of nitric oxide in neurodegenerative processes still remains incompletely characterized. Although nitric oxide has been reported to be an important mediator in neuronal degeneration in different models of cell death involving NMDA-receptor activation, increasing evidence for protective mechanisms has b...
journal_title：Neuroscience
pub_type： 杂志文章
doi：10.1016/s0306-4522(99)00599-0
更新日期：2000-01-01 00:00:00
abstract：:Amyloid deposits in Alzheimer's disease, Down's syndrome and aged brain are composed largely of A beta protein, which is generated by proteolytic processing of beta-amyloid precursor protein. Proteases responsible for liberating the A beta protein from the precursor have not yet been identified. Here, we examined the ...
journal_title：Neuroscience
pub_type： 杂志文章
doi：10.1016/0306-4522(94)90490-1
更新日期：1994-06-01 00:00:00
abstract：:Tau hyperphosphorylation leads to formation of paired helical filament/neurofibrillary tangles, the hallmark lesion seen in Alzheimer's disease (AD) brain. An imbalanced regulation in protein kinases and protein phosphatases in the affected neurons is proposed to be a reasonable causative factor to the disease process...
journal_title：Neuroscience
pub_type： 杂志文章
doi：10.1016/s0306-4522(02)00697-8
更新日期：2003-01-01 00:00:00
abstract：:The development of chronic pain is associated with activity-dependent plastic changes in neuronal structures in the peripheral and central nervous system. In order to investigate the time-dependent processing of afferent noxious stimuli in the spinal cord we employed the quantitative autoradiographic 2-deoxyglucose te...
journal_title：Neuroscience
pub_type： 杂志文章
doi：10.1016/s0306-4522(99)00186-4
更新日期：1999-01-01 00:00:00
abstract：:We investigated in this study the pharmacological properties of AC-3933 (5-(3-methoxyphenyl)-3-(5-methyl-1,2,4-oxadiazol-3-yl)-1,6-naphthyridin-2(1H)-one), a novel benzodiazepine receptor (BzR) partial inverse agonist. AC-3933 potently inhibited [3H]-flumazenil binding to rat whole brain membrane with a Ki value of 5....
journal_title：Neuroscience
pub_type： 杂志文章
doi：10.1016/j.neuroscience.2013.10.031
更新日期：2014-01-03 00:00:00
abstract：:The relationship between discharge rates of locus coeruleus noradrenergic neurons and rates of norepinephrine release was examined in the anesthetized rat. Neuronal discharge rates of locus coeruleus neurons were altered and quantified using a combined recording-infusion probe. Peri-locus coeruleus infusions of either...
journal_title：Neuroscience
pub_type： 杂志文章
doi：10.1016/s0306-4522(99)00276-6
更新日期：1999-01-01 00:00:00
abstract：:Estrogen is likely involved in the gender specific differences in coping with stress. Activation of catecholamine (CA) biosynthetic enzyme gene expression in central and peripheral CA systems plays a key role in response to stress and in regulation of the cardiovascular system. Here we examined whether estradiol can m...
journal_title：Neuroscience
pub_type： 杂志文章
doi：10.1016/j.neuroscience.2004.12.040
更新日期：2005-01-01 00:00:00
abstract：:The calcium binding protein, Calbindin-D28k, is known to be localized within spiny neurons of the matrix of the dorsal striatum, caudate-putamen nuclei. This compartment is also known to contain an abundance of GABAergic neurons and to receive extensive input from excitatory limbic and cortical afferents whose activat...
journal_title：Neuroscience
pub_type： 杂志文章
doi：10.1016/0306-4522(95)00441-6
更新日期：1996-03-01 00:00:00
abstract：:In order to determine which neurotransmitters and neuropeptides are utilized by the neurons of the mesencephalic trigeminal nucleus and by the fibres making synaptic contact with these primary sensory cells, we have set up an immunohistochemical study using antibodies against 17 major neurotransmitters and neuropeptid...
journal_title：Neuroscience
pub_type： 杂志文章
doi：10.1016/0306-4522(90)90410-6
更新日期：1990-01-01 00:00:00
abstract：:Activation of neurokinin-1 (NK-1) receptors in the rostral ventromedial medulla (RVM) can facilitate pain transmission in conditions such as inflammation, and thereby contribute to hyperalgesia. Since blockade of NK-1 receptors in the RVM can attenuate hyperalgesia produced by prolonged inflammation, we examined the r...
journal_title：Neuroscience
pub_type： 杂志文章
doi：10.1016/j.neuroscience.2012.08.029
更新日期：2012-11-08 00:00:00
abstract：:The cellular mechanisms underlying the genesis of thalamic ponto-geniculo-occipital waves were studied in reserpinized cats under urethane anaesthesia. Simultaneous field potential and intracellular recordings were performed in the lateral geniculate nucleus after acute lesions of retinal and visual cortical inputs. I...
journal_title：Neuroscience
pub_type： 杂志文章
doi：10.1016/0306-4522(89)90028-6
更新日期：1989-01-01 00:00:00
abstract：OBJECT:The aim of this study is to explore the changes of inter-hemispheric functional connectivity in patients with unilateral brachial plexus injury. METHODS:Nine patients with five roots of unilateral brachial plexus avulsion injury and 11 healthy controls were recruited in this study. Resting-state functional conn...
journal_title：Neuroscience
pub_type： 杂志文章
doi：10.1016/j.neuroscience.2013.03.048
更新日期：2013-07-23 00:00:00
abstract：:Cerebral ischemia is the most common cause of stroke with high morbidity, disability and mortality. Sirtuin-2 (Sirt2), a vitally important NAD+-dependent deacetylase which has been widely researched in central nervous system diseases, has also been identified as a promising treatment target using its specific inhibito...
journal_title：Neuroscience
pub_type： 杂志文章
doi：10.1016/j.neuroscience.2018.01.040
更新日期：2018-03-15 00:00:00
abstract：:The effect of muscarinic agonists on the spontaneous release of [3H]GABA was investigated in vitro on rat substantia nigra slices. Acetylcholine (5 x 10(-5) M) in the presence of eserine (5 x 10(-5) M) induced a 12.3% increase of the spontaneous release of [3H]GABA. Similarly, carbachol (5 x 10(-4) M) enhanced by 9% t...
journal_title：Neuroscience
pub_type： 杂志文章
doi：10.1016/0306-4522(94)90567-3
更新日期：1994-12-01 00:00:00
abstract：:The hippocampal CA1 region receives cortical information via two main inputs: directly via the perforant (temporoammonic) path (pp-CA1 synapse) and indirectly via the tri-synaptic pathway. Although synaptic plasticity has been reported at the pp-CA1 synapse of freely behaving animals, the mechanisms underlying this ph...
journal_title：Neuroscience
pub_type： 杂志文章
doi：10.1016/j.neuroscience.2015.03.014
更新日期：2015-11-19 00:00:00
abstract：:Several types of brain injuries have been associated with alterations in the striatal expression of neurotrophic factors, including glial cell line-derived neurotrophic factor (GDNF). However, contradictory results on the striatal expression of GDNF have been reported in different animal models of Parkinson's disease....
journal_title：Neuroscience
pub_type： 杂志文章
doi：10.1016/j.neuroscience.2009.04.036
更新日期：2009-08-04 00:00:00
abstract：:Both [3H]clonidine and [3H]idazoxan bind to alpha 2 adrenoceptors. The former also labels imidazoline receptors, and the latter non-adrenergic idazoxan binding sites. In order to investigate whether the imidazoline receptors and non-adrenergic idazoxan binding sites are identical, we compared the binding characteristi...
journal_title：Neuroscience
pub_type： 杂志文章
doi：10.1016/0306-4522(94)90179-1
更新日期：1994-04-01 00:00:00
abstract：:Tianeptine (Tian) has been widely used in treating mood and anxiety disorders, and recently as a nootropic to improve cognitive performance. However, its mechanisms of action are insufficiently clear. We used a comparative proteomic approach to identify sub-proteome changes in hippocampal cytosol and non-synaptic mito...
journal_title：Neuroscience
pub_type： 杂志文章
doi：10.1016/j.neuroscience.2020.09.061
更新日期：2020-12-15 00:00:00
abstract：:The nucleus tractus solitarius is a key brain centre involved in the regulation of numerous autonomic functions. The present study has employed in vitro autoradiography and in vivo microdialysis to investigate the presence and function of nicotinic acetylcholine receptors located in the medial nucleus tractus solitari...
journal_title：Neuroscience
pub_type： 杂志文章
doi：10.1016/s0306-4522(97)00476-4
更新日期：1998-04-01 00:00:00
abstract：:Peroxisome proliferator-activated receptor gamma (PPARγ) belongs to a family of ligand-activated transcription factors, and its ligands are known to control many physiological and pathological conditions. The hypothesis of our study was that the PPARγ agonist (rosiglitazone) could mediate tumor necrosis factor alpha (...
journal_title：Neuroscience
pub_type： 杂志文章
doi：10.1016/j.neuroscience.2012.11.003
更新日期：2013-01-15 00:00:00
abstract：:Calcineurin (PP2B) is a Ca(2+)-dependent protein phosphatase enriched in the brain that takes part in intracellular signaling pathways regulating synaptic plasticity and neuronal functions. Calcineurin-dependent pathways are important for complex brain functions such as learning and memory. More recently, they have be...
journal_title：Neuroscience
pub_type： 杂志文章
doi：10.1016/j.neuroscience.2006.11.030
更新日期：2007-02-23 00:00:00
abstract：:GABAA-receptors in the brain display a striking structural heterogeneity, which is based on a multiplicity of diverse subunits. The allocation of GABAA-receptor subtypes to identified neurons is essential for an analysis of the functional significance of receptor heterogeneity. Among GABA-receptive neurons, well-chara...
journal_title：Neuroscience
pub_type： 杂志文章
doi：10.1016/0306-4522(93)90582-z
更新日期：1993-06-01 00:00:00
abstract：:Physiological studies suggest visceral spinal afferents are generally small diameter, unmyelinated C-fibers or myelinated Adelta-fibers, but little is known about the size and chemical phenotypes of visceral sensory neurons supplying the small intestine. This study examines the size and expression patterns of transien...
journal_title：Neuroscience
pub_type： 杂志文章
doi：10.1016/j.neuroscience.2008.06.071
更新日期：2008-10-02 00:00:00
abstract：:Lack of dystrophin in mdx mice leads to muscle fibre degeneration followed by the formation of new myofibres. This degeneration-regeneration event occurs in clusters. It is accompanied by inflammation and remodelling of the intramuscular terminal nerve fibres. Since the growth-associated protein B-50/GAP-43 has been s...
journal_title：Neuroscience
pub_type： 杂志文章
doi：10.1016/s0306-4522(96)83017-x
更新日期：1996-02-01 00:00:00
abstract：:Ponto-geniculo-occipital waves and rapid eye movements (eye saccades) are two prominent phasic events of paradoxical sleep which occur in conjunction. Although they have been studied intensively, the neuronal link between these two events is still poorly understood. On the basis of our previous results, combining brai...
journal_title：Neuroscience
pub_type： 杂志文章
doi：10.1016/s0306-4522(98)00045-1
更新日期：1998-09-01 00:00:00
abstract：:The midbrain periaqueductal gray matter has been identified as a reflex centre located uppermost in the central organization of diverse defensive reactions. We recently found that when activated, the caudal third of the lateral periaqueductal gray was also capable of provoking a marked increase in cortical blood flow....
journal_title：Neuroscience
pub_type： 杂志文章
doi：10.1016/s0306-4522(96)00705-1
更新日期：1997-07-01 00:00:00
abstract：:The caudal anterior cingulate cortex (cAC) is an essential component of the circuitry involved in acquisition of forebrain-dependent trace eyeblink conditioning. Lesions of the cAC prevent trace eyeblink conditioning [Weible AP, McEchron MD, Disterhoft JF (2000) Cortical involvement in acquisition and extinction of tr...
journal_title：Neuroscience
pub_type： 杂志文章
doi：10.1016/j.neuroscience.2006.11.046
更新日期：2007-03-02 00:00:00
abstract：:The mechanism underlying phencyclidine (PCP)-induced apoptosis in perinatal rats and the development of schizophrenia-like behaviors is incompletely understood. We used antagonists for N-methyl-D-aspartate (NMDA) receptor subunit NR2A- and NR2B-containing NMDA receptor to test the hypothesis that the behavioral and ap...
journal_title：Neuroscience
pub_type： 杂志文章
doi：10.1016/j.neuroscience.2009.07.058
更新日期：2009-11-10 00:00:00
abstract：:Manganese-enhanced MRI (MEMRI) is a newly developed noninvasive imaging technique of brain activities. The signal intensity of MEMRI reflects cumulative activities of the neurons. To validate the use of MEMRI technique to investigate the neural mechanisms of learning and memory, we tried to map brain areas involved in...
journal_title：Neuroscience
pub_type： 杂志文章
doi：10.1016/j.neuroscience.2010.02.027
更新日期：2010-05-05 00:00:00
