New Genes Causing Hereditary Parkinson's Disease or Parkinsonism.

abstract：PURPOSE OF REVIEW:The proportion to which genetic and environmental factors contribute to the etiology of multiple sclerosis (MS) is still incompletely understood. An interesting association between MS etiology and obesity has recently been shown although the mechanisms underlying this association are still unknown. We...

journal_title：Current neurology and neuroscience reports

authors： Huitema MJD,Schenk GJ

更新日期：2018-03-10 00:00:00

abstract：:Although theories regarding headache originating in the neck have existed for more than 150 years, the term "cervicogenic headache" originated in 1983. Early descriptions pinpoint the characteristic symptoms as dizziness, visual disturbances, tinnitus, and "posterior" headache, conceivably as a consequence of arthrosi...

journal_title：Current neurology and neuroscience reports

authors： Antonaci F,Sjaastad O

更新日期：2011-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this review is to summarize current conceptual models of cognitive reserve (CR) and related concepts and to discuss evidence for these concepts within the context of aging and Alzheimer's disease. RECENT FINDINGS:Evidence to date supports the notion that higher levels of CR, as measured by...

journal_title：Current neurology and neuroscience reports

authors： Pettigrew C,Soldan A

更新日期：2019-01-09 00:00:00

abstract：PURPOSE OF REVIEW:Neurogenic stunned myocardium (NSM) is a poorly recognized cardiac manifestation of neurological illness. This review addresses the contemporary understanding of NSM pathophysiology, epidemiology, diagnosis, and clinical management. RECENT FINDINGS:While the precise pathophysiology and diagnosis rema...

journal_title：Current neurology and neuroscience reports

authors： Kenigsberg BB,Barnett CF,Mai JC,Chang JJ

更新日期：2019-11-13 00:00:00

abstract：:Chronic migraine occurs in about 3% of pediatric headaches. Many would be intractable to more than two preventive medications. OnabotulinumtoxinA has been approved by the US Food and Drug Administration for the use of chronic migraine in adults in 2010. Data on effectiveness and tolerability in the pediatric populatio...

journal_title：Current neurology and neuroscience reports

authors： Kabbouche M,O'Brien H,Hershey AD

更新日期：2012-04-01 00:00:00

abstract：:Syringobulbia is an uncommon condition, usually a late complication of syringomyelia. It has predilection for the dorsolateral region of the medulla leading to damage to vestibular nuclei and their connections, as well as to the descending sympathetic fibers. Oscillopsia, nystagmus, and Horner syndrome are frequent ma...

journal_title：Current neurology and neuroscience reports

authors： Nogués M,López L,Meli F

更新日期：2010-11-01 00:00:00

abstract：:Despite the growing awareness of mild traumatic brain injury in military and civilian populations, understanding of the acute and chronic effects of concussion on central nervous system structure and function is limited. Even less is understood about the underpinnings of the cardinal postconcussive symptom, post-traum...

journal_title：Current neurology and neuroscience reports

authors： Monteith TS,Borsook D

更新日期：2014-02-01 00:00:00

abstract：:Whipple disease is a rare disease caused by infection with the bacterium Tropheryma whippelii. Humans are the only known host for the infection. The signs of systemic infection include gastrointestinal problems, weight loss, and arthritis. Signs of central nervous system infection include cognitive changes, supranucle...

journal_title：Current neurology and neuroscience reports

authors： Louis ED

更新日期：2003-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Hiccups are a common problem that crosses multiple disciplines including neurology, gastroenterology and pulmonology, and primary care. There are no formal guidelines to the treatment of intractable hiccups and treatment is based on experience and anecdotal evidence often relying on older medications....

journal_title：Current neurology and neuroscience reports

authors： Rouse S,Wodziak M

更新日期：2018-06-22 00:00:00

abstract：:Microglial activation is a key aspect of the neuroinflammatory process in neurodegenerative disorders including idiopathic and atypical parkinsonian disorders. Using positron emission tomography, it has become possible to image this phenomenon in vivo and over the last years patterns of microglia activation correspond...

journal_title：Current neurology and neuroscience reports

authors： Gerhard A

更新日期：2013-12-01 00:00:00

abstract：:Lipid storage myopathy (LSM) is pathologically characterized by prominent lipid accumulation in muscle fibers due to lipid dysmetabolism. Although extensive molecular studies have been performed, there are only four types of genetically diagnosable LSMs: primary carnitine deficiency (PCD), multiple acyl-coenzyme A deh...

journal_title：Current neurology and neuroscience reports

authors： Liang WC,Nishino I

更新日期：2011-02-01 00:00:00

abstract：:The subjects of this review are the various types of optic nerve disease that involve autoimmune mechanisms, broadly defined. These include optic neuropathy caused by direct inflammatory involvement of the nerve parenchyma and optic nerve damage as an ischemic sequel to primary vasculitis, although there is naturally ...

journal_title：Current neurology and neuroscience reports

authors： Goodwin J

更新日期：2006-09-01 00:00:00

abstract：:Over the past 10 years, the Food and Drug Administration has approved eight prophylactic antiepileptic drugs (AEDs). Although the goal of universal seizure control without side effects has not been reached, the tolerability of medications has improved. This paper reviews the AEDs introduced since 1993 and tries to obj...

journal_title：Current neurology and neuroscience reports

authors： Weinstein SL,Conry J

更新日期：2002-03-01 00:00:00

abstract：:Gray matter demyelination is frequent and extensive in most patients with multiple sclerosis (MS) and has recently received much attention in neuropathologic and imaging studies. Gray matter lesions show distinct pathologic features that make their detection difficult with conventional imaging techniques. Thus, despit...

journal_title：Current neurology and neuroscience reports

authors： Wegner C,Stadelmann C

更新日期：2009-09-01 00:00:00

abstract：:Sleep and circadian disturbances are common among patients with dementia. Symptomatic manifestations vary according to dementia subtype, with one commonly shared pattern--the irregular sleep-wake rhythm (ISWR), a circadian disorder characterized by an absence of the sleepwake cycle’s circadian synchronization. Hypothe...

journal_title：Current neurology and neuroscience reports

authors： Zhou QP,Jung L,Richards KC

更新日期：2012-04-01 00:00:00

abstract：:Despite increased understanding of its potential complications, status epilepticus (SE) frequently remains difficult to diagnose and treat. Advances in continuous electroencephalogram (EEG) monitoring facilitate more rapid identification of SE, even without visible clinical signs of seizures. EEG monitoring assists in...

journal_title：Current neurology and neuroscience reports

authors： Selvitelli M,Drislane FW

更新日期：2007-11-01 00:00:00

abstract：:Multiple sclerosis (MS) is a chronic inflammatory and demyelinating disease of the central nervous system. Although the immune system seems to play an important role in the pathogenesis of disease, target antigens are still uncertain and pathways leading to tissue destruction have not been fully elucidated. Recent stu...

journal_title：Current neurology and neuroscience reports

authors： Hemmer B,Kieseier B,Cepok S,Hartung HP

更新日期：2003-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Our purpose is to review evidence relating to the concept that interictal epileptiform discharges (IEDs) impair brain performance. RECENT FINDINGS:Sophisticated measures of motor and cognitive performance have clarified older observations, confirming that in both animals and humans, IEDs affect aspec...

journal_title：Current neurology and neuroscience reports

authors： Faught E,Karakis I,Drane DL

更新日期：2018-10-08 00:00:00

abstract：:Headache attributable to disorders of homeostasis represents a diverse diagnostic category in which external (i.e., high-altitude) or internal (i.e., fasting) demands exceed homeostatic capacity, resulting in symptomatic headaches. Metabolic headaches, especially fasting headache, have been observed to be common in th...

journal_title：Current neurology and neuroscience reports

authors： Grewal P,Smith JH

更新日期：2017-01-01 00:00:00

abstract：:The brain tumor community is a unique, underserved population that has not seen significant improvements in survival over the last four decades. In the search for effective treatments for brain tumors, nonprofit patient advocacy organizations identify and fill the gaps that the for-profit sector and the government hav...

journal_title：Current neurology and neuroscience reports

authors： Rhee M,Mui P,Cadogan C,Imerman J,Lindsell S,Samant LT

更新日期：2014-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Occipital neuralgia (ON) and cervicogenic headache (CGH) are secondary headache disorders with occipital pain as a key feature. Due to significant phenotypic overlap, differentiating ON and CGH from primary headache disorders such as migraine or tension-type headache, or other secondary headache disor...

journal_title：Current neurology and neuroscience reports

authors： Barmherzig R,Kingston W

更新日期：2019-03-19 00:00:00

abstract：:Successful critical care management of patients with aneurysmal subarachnoid hemorrhage requires a thorough understanding of the disease and its complications and a familiarity with modern multimodality neuromonitoring technology. This article reviews the natural history of aneurysmal subarachnoid hemorrhage and strat...

journal_title：Current neurology and neuroscience reports

authors： Levine JM

更新日期：2008-11-01 00:00:00

abstract：:Lyme disease is due to infection with a tick-borne spirochete, Borrelia burgdorferi. Risk for infection is confined to regions that contain the Ixodid tick vector. Characteristic skin, musculoskeletal, cardiac, ocular, and neurologic disorders are associated with the local, early dissemination and late stages of infec...

journal_title：Current neurology and neuroscience reports

authors： Coyle PK

更新日期：2002-11-01 00:00:00

abstract：:Iatrogenic fungal infections of the central nervous system had been considered a medical curiosity. Generally, they are a rare isolated complication of neurosurgical procedures, but periodically these infections are observed in larger populations as a result of exposure to contaminated materials during diagnostic or t...

journal_title：Current neurology and neuroscience reports

authors： Lahoti S,Berger JR

更新日期：2013-11-01 00:00:00

abstract：:Tumefactive demyelinating lesions are rare consequences of central nervous system (CNS) idiopathic inflammatory demyelinating diseases. Tumefactive demyelinating lesions pose a diagnostic challenge because they can mimic tumors and abscesses and because they can be caused by a heterogeneous range of disorders. This ar...

journal_title：Current neurology and neuroscience reports

authors： Frederick MC,Cameron MH

更新日期：2016-03-01 00:00:00

abstract：:Recent advances in the development and administration of chemotherapy for malignant diseases have led to prolonged survival of patients and the promise of a return to normal lives. The cost of progress comes with a price, however, and the nervous system is frequently the target of therapy-induced toxicity. Unlike more...

journal_title：Current neurology and neuroscience reports

authors： Malik B,Stillman M

更新日期：2008-01-01 00:00:00

abstract：:Although major advancements have been made in the treatment of HIV infection, graft-versus-host reactions, and autoimmune diseases, an unexpected consequence of treatment has been the emergence of a devastating inflammatory syndrome, termed the immune reconstitution inflammatory syndrome (IRIS). The pathophysiology of...

journal_title：Current neurology and neuroscience reports

authors： McCarthy M,Nath A

更新日期：2010-11-01 00:00:00

abstract：PURPOSE OF REVIEW:GBA mutations are the most common known genetic cause of Parkinson's disease (PD). Its biological pathway may be important in idiopathic PD, since activity of the enzyme encoded by GBA, glucocerebrosidase, is reduced even among PD patients without GBA mutations. This article describes the structure an...

journal_title：Current neurology and neuroscience reports

authors： Gan-Or Z,Liong C,Alcalay RN

更新日期：2018-06-08 00:00:00

abstract：:Hepatic and gastrointestinal disorders can produce a wide spectrum of neurologic complications both affecting the central nervous system (CNS) and the peripheral nervous system. These manifestations range in severity from coma in acute liver failure and acute pancreatitis, to minor cognitive changes in chronic portosy...

journal_title：Current neurology and neuroscience reports

authors： Ferro JM,Oliveira S

更新日期：2014-10-01 00:00:00

abstract：:Over the past few decades, intracranial monitoring technologies focused on treating and preempting secondary injury after traumatic brain injury (TBI) have experienced considerable growth. A physiological measure fundamental to the management of these patients is cerebral blood flow (CBF), which may be determined dire...

journal_title：Current neurology and neuroscience reports

authors： Akbik OS,Carlson AP,Krasberg M,Yonas H

更新日期：2016-08-01 00:00:00