Abstract:
:Recent trends in cancer therapy have begun emphasizing the use of precision medicine, especially genetic tools, in the evaluation of malignancies and decision-making. Prostate cancer is a malignancy where the benefits and utility of screening and early treatment are still heavily controversial. A recent paper in the New England Journal of Medicine found that patients with metastatic prostate cancer presented germline mutations in DNA-repair genes at a significantly higher incidence than those with localized prostate cancer. These findings indicate the need for further research in this field as genetic differences between metastatic and localized prostate cancer could have great clinical value.
journal_name
Cancer Biol Therjournal_title
Cancer biology & therapyauthors
Hauke RJ Jr,Sissung TM,Figg WDdoi
10.1080/15384047.2017.1345398subject
Has Abstractpub_date
2017-08-03 00:00:00pages
545-546issue
8eissn
1538-4047issn
1555-8576journal_volume
18pub_type
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