当前位置： SCI文献检索 > CLINICAL AND EXPERIMENTAL RHEUMATOLOGY期刊下所有文献 > A meta-analysis of avascular necrosis in systemic lupus erythematosus: prevalence and risk factors.

A meta-analysis of avascular necrosis in systemic lupus erythematosus: prevalence and risk factors.

Abstract：

OBJECTIVES:To determine the prevalence of and risk factors for avascular necrosis (AVN) in systemic lupus erythematosus (SLE). METHODS:MEDLINE, CINAHL, Web of Science, EMBASE and Cochrane Library were searched from inception to July, 2015 and a random effects model was used to combine frequencies; study quality was assessed using STROBE. RESULTS:2,041 citations identified 62 articles. Many results had high heterogeneity. The prevalence of symptomatic AVN was 9% (range 0.8%-33%) in SLE and 29% for asymptomatic AVN; femoral head was the most common location (8.0%). High-dose corticosteroids (CS) any CS use, maximum and cumulative dose, pulse therapy, and CS side-effects (hypertension, Cushings, but not diabetes mellitus or hyperlipidaemia) were associated with AVN, as was active SLE (cutaneous vasculitis, renal and neuropsychiatric manifestations, serositis, cytopenias) and Sjögren's, Raynaud's phenomenon, arthritis, cyclophosphamide (but not azathioprine mycophenolate mofetil, or methotrexate) and more damage (excluding musculoskeletal system). Antimalarial drugs were not protective. Rashes and oral ulcers were not associated with AVN. Mean daily dose of CS and duration of CS use had no impact on AVN occurence. Autoantibodies and other immunological markers did not predispose to AVN, except IgM anticardiolipin antibodies which doubled the risk. African Americans experienced more AVN (OR 1.8, p=0.04). CONCLUSIONS:AVN may occur in 1/3 of patients with SLE and 9% with symptoms. Features of active organ SLE (CNS, renal, cutaneous vasculitis, serositis, cytopenias) are associated with AVN as are CS, especially early in disease and at high doses. Those with early CS side-effects seem to have the highest risk of AVN.

journal_name

Clin Exp Rheumatol

journal_title

Clinical and experimental rheumatology

authors

Nevskaya T,Gamble MP,Pope JE

subject

Has Abstract

pub_date

2017-07-01 00:00:00

pages

700-710

issue

4

eissn

0392-856X

issn

1593-098X

pii

11045

journal_volume

35

pub_type

杂志文章,meta分析,评审

相关文献

CLINICAL AND EXPERIMENTAL RHEUMATOLOGY文献大全
  • Association of salivary S. mutans colonisation and mannose-binding lectin deficiency with gender in Behçet's disease.

    abstract：OBJECTIVE:The present study aimed to investigate the interactions among salivary S. mutans colonisation, serum mannose binding lectin level (MBL), oral ulcer activity and disease course in patients with Behçet's disease (BD). METHODS:One hundred and six BD patients, 25 patients with rheumatoid arthritis (RA) and 42 he...

    journal_title：Clinical and experimental rheumatology

    pub_type： 杂志文章

    doi：

    authors： Mumcu G,Inanc N,Aydin SZ,Ergun T,Direskeneli H

    更新日期：2009-03-01 00:00:00

  • Factors associated with damage in patients with familial Mediterranean fever.

    abstract：OBJECTIVES:Defining predictors of damage would improve patient care. We applied damage indexes to patients with familial Mediterranean fever (FMF) and identified the predictors of damage. METHODS:This is a cross-sectional analysis of 926 FMF patients, who fulfilled the Tel-Hashomer criteria and had at least six months...

    journal_title：Clinical and experimental rheumatology

    pub_type： 杂志文章

    doi：

    authors： Babaoglu H,Armagan B,Bodakci E,Satis H,Atas N,Sari A,Yasar Bilge NS,Bilici Salman R,Yardimci GK,Avanoglu Guler A,Karadeniz H,Kilic L,Ozturk MA,Goker B,Haznedaroglu S,Kalyoncu U,Kasifoglu T,Tufan A

    更新日期：2020-09-01 00:00:00

  • A complex pattern of autonomic dysfunction in familial Mediterranean fever. Results from a controlled cross-sectional study.

    abstract：OBJECTIVES:Autonomic dysfunction (AD) has been described in various chronic inflammatory diseases. Studies of AD in patients with familial Mediterranean fever (FMF) are inconclusive. We aimed to assess AD in a cohort of FMF patients. METHODS:Signs and symptoms of AD were investigated in patients with FMF and compared ...

    journal_title：Clinical and experimental rheumatology

    pub_type： 杂志文章

    doi：

    authors： Moog P,Valda K,Eren OE,Rauschel V,Kossegg SJ,Bachmann Q,Schmaderer C,Straube A,Schulze-Koops H,Witt M

    更新日期：2019-11-01 00:00:00

  • Serum leptin, resistin, visfatin and adiponectin levels in tumor necrosis factor receptor-associated periodic syndrome (TRAPS).

    abstract：OBJECTIVES:The aims of our study were to evaluate serum leptin, resistin, visfatin and adiponectin levels in patients with tumour necrosis factor receptor-associated periodic syndrome (TRAPS), in comparison to healthy controls, and to correlate their levels to parameters of disease activity and/or severity. METHODS:Se...

    journal_title：Clinical and experimental rheumatology

    pub_type： 杂志文章

    doi：

    authors： Cantarini L,Obici L,Simonini G,Cimaz R,Bacarelli MR,Merlini G,Vitale A,Lucherini OM,Brizi MG,Galeazzi M,Fioravanti A

    更新日期：2012-05-01 00:00:00

  • Current management strategies for systemic sclerosis.

    abstract：:Systemic sclerosis remains a challenging disease despite progress that has taken place in the management of organ-based complications. Overall management strategies need to take into account the features of the disease that are common to almost all patients such as skin involvement, gastro-oesophageal manifestations a...

    journal_title：Clinical and experimental rheumatology

    pub_type： 杂志文章,评审

    doi：

    authors： Nihtyanova SI,Ong VH,Denton CP

    更新日期：2014-03-01 00:00:00

  • Benign monoclonal gammopathy with IgG anti-DNA, anti-Sm and anti-F(ab')2 activity.

    abstract：OBJECTIVE:To study anti-DNA idiotypic markers and anti-DNA activity in human monoclonal immunoglobulin proteins. METHODS:Seventy human IgG M-components intentionally selected for cationic electrophoretic characteristics were studied for F4 and 31 anti-DNA idiotypic markers and anti-DNA as well as anti-F(ab')2 antibody...

    journal_title：Clinical and experimental rheumatology

    pub_type： 杂志文章

    doi：

    authors： Williams RC Jr,Malone CC,Silvestris F,Nickerson KG

    更新日期：1997-01-01 00:00:00

  • The frequency of Leu 1+B cells in autoantibody positive and negative autoimmune diseases and in neonatal cord blood.

    abstract：:There is increasing evidence supporting the involvement of Leu 1+B cells in the development of human autoimmune diseases. In this study, the frequency of Leu 1+B cells has been analysed by a multiparameter FACS machine in newborn cord blood, and in the peripheral blood of several autoimmune patients and their healthy ...

    journal_title：Clinical and experimental rheumatology

    pub_type： 杂志文章

    doi：

    authors： Kazbay K,Osterland CK

    更新日期：1990-05-01 00:00:00

  • IL-34 modulates rheumatoid synovial fibroblasts proliferation and migration via ERK/AKT signalling pathway.

    abstract：OBJECTIVES:The interface between pro-inflammatory cytokines and rheumatoid synovial fibroblast (sFLS) has central effects on rheumatoid arthritis (RA). The present study aimed to explore the role of IL-34 expression as one of major cytokine implicated in RA. METHODS:We examined the expression of IL-34 after RA sFLS st...

    journal_title：Clinical and experimental rheumatology

    pub_type： 杂志文章

    doi：

    authors： Elkhider A,Wei J,Al-Azab M,Tang Y,Walana W,Li W,Yuan B,Ye Y,Wang G,Zhang Y,Li X

    更新日期：2020-05-01 00:00:00

  • Psychological side effects of MTX treatment in juvenile idiopathic arthritis: a pilot study.

    abstract：OBJECTIVE:To document the psychological side effects of methotrexate (MTX) treatment in children with juvenile idiopathic arthritis (JIA) and to explore the usefulness of psychological therapy to ameliorate these side effects. METHODS:The patients included in this study consisted of 29 patients with JIA using MTX. Of ...

    journal_title：Clinical and experimental rheumatology

    pub_type： 临床试验,杂志文章

    doi：

    authors： van der Meer A,Wulffraat NM,Prakken BJ,Gijsbers B,Rademaker CM,Sinnema G

    更新日期：2007-05-01 00:00:00

  • Antiproliferative effects on human peripheral blood mononuclear cells and inhibition of in vitro immunoglobulin synthesis by Podophyllotoxin (CPH86) and by semisynthetic lignan glycosides (CPH82).

    abstract：:A mixture of natural and semisynthetic (modified) glycosides from Podophyllum emodi (Proresid) has been used for many years in the treatment of rheumatoid arthritis, but its use is hampered by gastrointestinal side effects. Highly purified podophyllotoxin (CPH86) and a preparation containing two semisynthetic podophyl...

    journal_title：Clinical and experimental rheumatology

    pub_type： 杂志文章

    doi：

    authors： Truedsson L,Geborek P,Sturfelt G

    更新日期：1993-03-01 00:00:00

  • Early detection of median nerve syndrome at the carpal tunnel with high-resolution 18 MHz ultrasonography in systemic sclerosis patients.

    abstract：OBJECTIVES:To investigate carpal tunnel syndrome (CTS) with ultrasound (US) in asymptomatic SSc patients and to seek out the relationship between CTS and SSc clinical variables METHODS:In 64 SSc patients (55 women and 9 men, mean age 57±14 years) and in 30 healthy controls, area (MNA), transverse (MNT) and anteroposte...

    journal_title：Clinical and experimental rheumatology

    pub_type： 杂志文章

    doi：

    authors： Bandinelli F,Kaloudi O,Candelieri A,Conforti ML,Casale R,Cammarata S,Grassiri G,Miniati I,Melchiorre D,Matucci-Cerinic M

    更新日期：2010-09-01 00:00:00

  • Chronic recurrent multifocal osteomyelitis presenting with Tolosa-Hunt syndrome in a 13-year-old boy.

    abstract：: ...

    journal_title：Clinical and experimental rheumatology

    pub_type： 信件

    doi：

    authors： Torreggiani S,Cinnante CM,Torcoletti M,Corona F,Agostoni C,Filocamo G

    更新日期：2017-05-01 00:00:00

  • Acetylcholinesterase-associated inflammation in patients with giant cell arteritis. Evaluation by histology and 11C-donepezil PET/CT.

    abstract：OBJECTIVES:To investigate the in-situ expression of acetylcholinesterase (AChE) in the inflamed vessel wall of patients with biopsy-positive giant cell arteritis (GCA) as compared to biopsy-negative non-GCA patients, and to evaluate the in-vivo expression of AChE in patients with large-vessel GCA (LVGCA) by 11C-donepez...

    journal_title：Clinical and experimental rheumatology

    pub_type： 杂志文章

    doi：

    authors： Therkildsen P,Nielsen BD,Hansen IT,Keller KK,Steiniche T,Gormsen LC,Borghammer P,Hauge EM

    更新日期：2019-03-01 00:00:00

  • Nailfold capillaroscopy in Sjögren's syndrome: a systematic literature review and standardised interpretation.

    abstract：OBJECTIVES:To identify the role of nailfold capillaroscopy (NC) in Sjögren's syndrome (SS). METHODS:The literature was systematically reviewed in three databases. All published original studies which assess patients with SS by NC were revised. A quality assessment was applied to all studies based on population descrip...

    journal_title：Clinical and experimental rheumatology

    pub_type： 杂志文章

    doi：

    authors： Melsens K,Leone MC,Paolino S,Elewaut D,Gerli R,Vanhaecke A,Peene I,Cutolo M,Smith V

    更新日期：2020-07-01 00:00:00

  • The 'head-to-head' comparison of etanercept and infliximab in treating children with juvenile idiopathic arthritis.

    abstract：OBJECTIVES:Our aim was to assess long-term efficacy and tolerability of etanercept and infliximab in patients with JIA. METHODS:This was an observational, retrospective study of 41 patients treated with anti-TNF therapy. We assessed clinical remission, flare, ACR improvement, improvement of DAS28, and JADAS. Some pati...

    journal_title：Clinical and experimental rheumatology

    pub_type： 杂志文章

    doi：

    authors： Lamot L,Bukovac LT,Vidovic M,Frleta M,Harjacek M

    更新日期：2011-01-01 00:00:00

  • Methotrexate and leflunomide combination therapy for patients with active rheumatoid arthritis.

    abstract：:An open-label, one-year study was conducted to evaluate the safety and clinical response to leflunomide and methotrexate combination therapy for rheumatoid arthritis. Study results revealed tolerable safety, no significant pharmacokinetic interactions between methotrexate and leflunomide, and suggested improved clinic...

    journal_title：Clinical and experimental rheumatology

    pub_type： 临床试验,杂志文章

    doi：

    authors： Mroczkowski PJ,Weinblatt ME,Kremer JM

    更新日期：1999-11-01 00:00:00

  • Brazil Patient Knowledge Questionnaire (PKQ) and evaluation of disease-specific knowledge in patients with rheumatoid arthritis.

    abstract：OBJECTIVE:To create a Brazilian version of the Patient Knowledge Questionnaire--PKQ, an instrument for measuring the knowledge of patients with rheumatoid arthritis (RA) as regards their disease, and through the use of this instrument, also measure the knowledge of RA patients from reference hospitals in the city of Sã...

    journal_title：Clinical and experimental rheumatology

    pub_type： 杂志文章

    doi：

    authors： Jennings F,Toffolo S,de Assis MR,Natour J

    更新日期：2006-09-01 00:00:00

  • Indirect comparison of anti-TNF-α agents for active ankylosing spondylitis: mixed treatment comparison of randomized controlled trials.

    abstract：OBJECTIVES:We aimed to identify different anti-TNF-α agents for ankylosing spondylitis (AS) assessed in randomised controlled trials (RCTs) and to compare them within a single evidence synthesis framework. METHODS:A Bayesian network analysis method was used to generate direct and indirect comparisons while maintaining...

    journal_title：Clinical and experimental rheumatology

    pub_type： 杂志文章,meta分析,评审

    doi：

    authors： Shu T,Chen GH,Rong L,Feng F,Yang B,Chen R,Wang J

    更新日期：2013-09-01 00:00:00

  • Corticotropin releasing hormone promoter polymorphisms in giant cell arteritis and polymyalgia rheumatica.

    abstract：OBJECTIVE:Giant cell (temporal) arteritis (GCA) and polymyalgia rheumatica (PMR) are different but overlapping diseases of unknown etiology affecting the elderly. Corticotropin-releasing hormone (CRH) helps to regulate the immune response and maintain homeostasis during inflammatory stress. CRH promoter region polymorp...

    journal_title：Clinical and experimental rheumatology

    pub_type： 杂志文章

    doi：

    authors： Gonzalez-Gay MA,Hajeer AH,Dababneh A,Garcia-Porrua C,Amoli MM,Thomson W,Ollier WE

    更新日期：2002-03-01 00:00:00

  • Rhein, a diacerhein-derived metabolite, modulates the expression of matrix degrading enzymes and the cell proliferation of articular chondrocytes by inhibiting ERK and JNK-AP-1 dependent pathways.

    abstract：OBJECTIVE:To determine the effects of rhein on the expression of matrix metalloproteinases (MMP-1, -3, 13) and ADAMTs 4, 5 (a disintegrin and metalloproteinase with thrombospondin type-I repeat)/aggrecanases-1, -2 in interleukin-1-stimulated bovine articular chondrocytes, and to investigate the signalling pathways invo...

    journal_title：Clinical and experimental rheumatology

    pub_type： 杂志文章

    doi：

    authors： Legendre F,Bogdanowicz P,Martin G,Domagala F,Leclercq S,Pujol JP,Ficheux H

    更新日期：2007-07-01 00:00:00

  • Actinically degenerate elastic tissue: the prime antigen in the giant cell (temporal) arteritis syndrome? New data from the posterior ciliary arteries.

    abstract：OBJECTIVE:To search for evidence of actinic elastotic degeneration (actinic arteriopathy) and giant cell arteritis (GCA) in the posterior ciliary arteries of eyes from aged white Australians. METHODS:Three hundred donor eyes were given to us by the Lions Eye Bank of New South Wales at Sydney Hospital. Of these, 146 fo...

    journal_title：Clinical and experimental rheumatology

    pub_type： 杂志文章

    doi：

    authors： O'Brien JP,Regan W

    更新日期：1998-01-01 00:00:00

  • Glucocorticoid-sparing in patients suffering from rheumatoid arthritis and treated with tocilizumab: the SPARE-1 study.

    abstract：OBJECTIVES:To describe steroid-sparing in rheumatoid arthritis (RA) patients treated with tocilizumab (TCZ). METHODS:To evaluate the proportion of RA patients treated with more than 5 mg of prednisone (or equivalent)/day and starting TCZ who can receive less than 5 mg/day after 12 months without intensification of dis...

    journal_title：Clinical and experimental rheumatology

    pub_type： 杂志文章,多中心研究

    doi：

    authors： Saraux A,Rouanet S,Flipo RM,Poncet JC,Fardellone P,Hilliquin P,Idier I,Cantagrel A

    更新日期：2016-03-01 00:00:00

  • The role of muscarinic acetylcholine receptor type 3 polypeptide (M3RP205-220) antibody in the saliva of patients with primary Sjögren's syndrome.

    abstract：BACKGROUND:Sjögren's syndrome (SS) is a chronic autoimmune disorder of unknown cause. Recent studies have shown that antimuscarinic acetylcholine type 3 receptor (M3R) antibodies can be detected in patients with Sjögren's syndrome (SS), but little is known about the diagnostic value of this antibody. OBJECTIVES:To ass...

    journal_title：Clinical and experimental rheumatology

    pub_type： 杂志文章

    doi：

    authors： He J,Qiang L,Ding Y,Wei P,Li YN,Hua H,Li ZG

    更新日期：2012-05-01 00:00:00

  • Skin manifestations of systemic lupus erythematosus refractory to multiple treatment modalities: poor results with mycophenolate mofetil.

    abstract：OBJECTIVE:Skin disease can be one of the most refractory clinical manifestations of systemic lupus erythematosus (SLE). The standard therapy consists of sunscreens, topical corticosteroids and antimalarials. However in difficult cases a variety of other drugs have been tried. Here we describe our clinical experience wi...

    journal_title：Clinical and experimental rheumatology

    pub_type： 杂志文章

    doi：

    authors： Pisoni CN,Obermoser G,Cuadrado MJ,Sanchez FJ,Karim Y,Sepp NT,Khamashta MA,Hughes GR

    更新日期：2005-05-01 00:00:00

  • Urinary soluble VCAM-1 in systemic lupus erythematosus: a clinical marker for monitoring disease activity and damage.

    abstract：OBJECTIVE:To determine the urinary levels of soluble vascular cell adhesion molecule-1 (VCAM-1) and intercellular adhesion molecule-1 (ICAM-1) in patients with systemic lupus erythematosus (SLE) and to assess their relationship with clinical and laboratory features and the degree of activity and damage associated with ...

    journal_title：Clinical and experimental rheumatology

    pub_type： 杂志文章

    doi：

    authors： Molad Y,Miroshnik E,Sulkes J,Pitlik S,Weinberger A,Monselise Y

    更新日期：2002-05-01 00:00:00

  • Psychological well-being in patients with primary Sjögren's syndrome.

    abstract：OBJECTIVES:To evaluate quality of life and psychological symptoms in patients with primary Sjögren's syndrome and to compare this with patients with rheumatoid arthritis. METHODS:A standardised questionnaire, the Psychological General Well-Being Index (PGWB), was used to examine the quality of life and psychological s...

    journal_title：Clinical and experimental rheumatology

    pub_type： 杂志文章

    doi：

    authors： Valtýsdóttir ST,Gudbjörnsson B,Hällgren R,Hetta J

    更新日期：2000-09-01 00:00:00

  • Impact of cardiac magnetic resonance imaging for assessment of Churg-Strauss syndrome: a cross-sectional study in 20 patients.

    abstract：OBJECTIVE:To examine the diagnostic contributions of cardiac magnetic resonance imaging (CMRI) with delayed-enhancement (DE) in patients with Churg-Strauss syndrome (CSS). METHODS:We consecutively recruited 14 men and 6 women (mean age: 50+/-14 years) with CSS (mean disease duration: 4.5+/-3.6 years) and investigated ...

    journal_title：Clinical and experimental rheumatology

    pub_type： 杂志文章

    doi：

    authors： Marmursztejn J,Vignaux O,Cohen P,Guilpain P,Pagnoux C,Gouya H,Mouthon L,Legmann P,Duboc D,Guillevin L

    更新日期：2009-01-01 00:00:00

  • Monoarticular corticosteroid injection versus systemic administration in the treatment of rheumatoid arthritis patients: a randomized double-blind controlled study.

    abstract：OBJECTIVE:To compare the efficacy and safety of intraarticular glucocorticoid injection to its systemic use for treatment of knee synovitis in rheumatoid patients. METHODS:A randomized double-blind controlled study was conducted including 60 patients with RA. Patients were randomized to receive either a single intraar...

    journal_title：Clinical and experimental rheumatology

    pub_type： 杂志文章,随机对照试验

    doi：

    authors： Konai MS,Vilar Furtado RN,Dos Santos MF,Natour J

    更新日期：2009-03-01 00:00:00

  • Helper (OKT4)/suppressor (OKT8) ratios in the peripheral blood and synovial fluid of patients with rheumatoid arthritis.

    abstract：:Lymphocyte subsets in the peripheral blood of 10 patients with RA were studied using monoclonal antibodies. The mean percentages of total T, T helper, T suppressor and TAR in the peripheral blood of RA patients were not different from those observed in normal controls. In the synovial fluid the mean percentages of T s...

    journal_title：Clinical and experimental rheumatology

    pub_type： 杂志文章

    doi：

    authors： Rueda HO,Schainberg H,Diniz R,Scheinberg MA

    更新日期：1984-10-01 00:00:00

  • Long-term prognosis of 69 patients with dermatomyositis or polymyositis.

    abstract：OBJECTIVES:To assess the long-term prognosis of dermatomyositis and pol myositis. METHODS:69 patients with dermatomyositis or polymyositis were selected according to the diagnostic criteria of Bohan and Peter and were followed up for a minimum of 6.3 years (for surviving patients) (mean 11.6 years). Clinical and biolo...

    journal_title：Clinical and experimental rheumatology

    pub_type： 杂志文章

    doi：

    authors： Maugars YM,Berthelot JM,Abbas AA,Mussini JM,Nguyen JM,Prost AM

    更新日期：1996-05-01 00:00:00