Endoscopic sclerotherapy for portal hypertension due to extrahepatic obstruction: long-term follow-up.

Abstract:

:Between 1982 and 1987, 43 patients with variceal bleeding due to extrahepatic portal obstruction were treated by repeated endoscopic injection sclerotherapy using 1% polidocanol intravariceally. This decreased rebleeding, as evidenced by a decrease in bleeding risk factor (BRF), mean transfusion requirement, and mean number of transfusions per patient per month of follow-up. Differences between pre- and postsclerotherapy parameters were significant (p less than 0.001). The varices were eradicated in 86% of patients. The mean sclerotherapy sessions required were 7.68 +/- 2.39 (SD). Complications were infrequent. Forty-three patients were followed from 5 to 68 months: cumulative survival was 97.7% and varices recurred in 16%. Sclerotherapy avoided a second operation in 21 postsurgical patients. Sclerotherapy for managing variceal bleeding due to extrahepatic portal obstruction is a reasonable alternative to surgery.

journal_name

Gastrointest Endosc

authors

Bhargava DK,Dwivedi M,Dasarathy S,Arora A

doi

10.1016/s0016-5107(89)72798-x

subject

Has Abstract

pub_date

1989-07-01 00:00:00

pages

309-11

issue

4

eissn

0016-5107

issn

1097-6779

pii

S0016-5107(89)72798-X

journal_volume

35

pub_type

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