当前位置： SCI文献检索 > GASTROINTESTINAL ENDOSCOPY期刊下所有文献 > Risk of advanced lesions at first follow-up colonoscopy in high-risk groups as defined by the United Kingdom post-polypectomy surveillance guideline: data from a single U.S. center.

Risk of advanced lesions at first follow-up colonoscopy in high-risk groups as defined by the United Kingdom post-polypectomy surveillance guideline: data from a single U.S. center.

Abstract：

BACKGROUND:The United Kingdom (U.K.) post-adenoma resection guidelines recommend earlier surveillance for patients with 5 or more adenomas or 3 to 4 adenomas of which one is 10 mm or larger compared with U.S. guidelines. OBJECTIVE:To evaluate the effect of using the U.K. guideline on a U.S. cohort of adenoma patients. DESIGN:Single-center, retrospective study. SETTING:Indiana University Hospital and an associated ambulatory surgery center. PATIENTS:A total of 1414 patients with baseline adenoma findings belonging to one of 5 risk categories and with a follow-up colonoscopy more than 200 days later. INTERVENTION:Colonoscopy, polypectomy. MAIN OUTCOME MEASUREMENTS:Incidence of advanced lesions at follow-up colonoscopy. RESULTS:Advanced neoplasms at follow-up occurred in 16.3% of patients with 5 or more adenomas including 1 that was 10 mm or larger, 8.6% of patients with 3 or 4 adenomas including 1 that was 10 mm or larger, 5% of those with 5 or more adenomas all smaller than 10 mm, 1.8% of those with 3 or 4 adenomas all smaller than 10 mm, and 1.4% of those with 1 to 2 adenomas smaller than 10 mm. Logistic regression analyses showed that the rate of advanced lesions at first follow-up was increased in persons with 3 or more baseline adenomas and at least 1 that is 10 mm or larger compared with those with 1 to 4 small baseline adenomas. LIMITATIONS:Single-center, retrospective study. CONCLUSIONS:Our results indicate the U.K. guideline predicts higher risk groups for advanced neoplasia at first follow-up. Our study had inadequate power to show better prediction of incident cancer. Additional study of other databases is warranted.

journal_name

Gastrointest Endosc

journal_title

Gastrointestinal endoscopy

authors

Vemulapalli KC,Rex DK

doi

10.1016/j.gie.2014.02.1029

subject

Has Abstract

pub_date

2014-08-01 00:00:00

pages

299-306

issue

2

eissn

0016-5107

issn

1097-6779

pii

S0016-5107(14)01199-7

journal_volume

80

pub_type

杂志文章

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