Abstract:
:The role of Chlamydia pneumoniae in the cause of lung cancer is controversial. In this study, we investigated the association between C. pneumoniae immunoglobulin (Ig) G antibodies and risk of lung cancer among non-smoking women. C. pneumoniae IgG antibody levels were compared between 192 adult Chinese women who met the diagnostic criteria of lung cancer and 90 healthy controls. C. pneumoniae IgG antibodies were tested with the use of an enzyme-linked immunosorbent assay. The prevalence of C. pneumoniae IgG seropositivity was 61.98% of cases and 28.89% of controls (P < 0.05). According to the results of the multiple logistic analysis model, the odds ratios for C. pneumoniae IgG antibody seropositivity, body mass index, and educational levels were 3.919 (P < 0.001), 0.731 (P= 0.274), and 1.646 (P= 0.069), respectively. C. pneumoniae infection may be a risk factor for lung cancer.
journal_name
Thorac Cancerjournal_title
Thoracic cancerauthors
Liu Z,Su M,Yu SC,Yin ZH,Zhou BSdoi
10.1111/j.1759-7714.2010.00021.xsubject
Has Abstractpub_date
2010-09-01 00:00:00pages
126-129issue
3eissn
1759-7706issn
1759-7714journal_volume
1pub_type
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