Association of Chlamydia pneumoniae immunoglobulin G antibodies with the risk of lung cancer among non-smoking women in Liaoning, China.

Abstract:

:The role of Chlamydia pneumoniae in the cause of lung cancer is controversial. In this study, we investigated the association between C. pneumoniae immunoglobulin (Ig) G antibodies and risk of lung cancer among non-smoking women. C. pneumoniae IgG antibody levels were compared between 192 adult Chinese women who met the diagnostic criteria of lung cancer and 90 healthy controls. C. pneumoniae IgG antibodies were tested with the use of an enzyme-linked immunosorbent assay. The prevalence of C. pneumoniae IgG seropositivity was 61.98% of cases and 28.89% of controls (P < 0.05). According to the results of the multiple logistic analysis model, the odds ratios for C. pneumoniae IgG antibody seropositivity, body mass index, and educational levels were 3.919 (P < 0.001), 0.731 (P= 0.274), and 1.646 (P= 0.069), respectively. C. pneumoniae infection may be a risk factor for lung cancer.

journal_name

Thorac Cancer

journal_title

Thoracic cancer

authors

Liu Z,Su M,Yu SC,Yin ZH,Zhou BS

doi

10.1111/j.1759-7714.2010.00021.x

subject

Has Abstract

pub_date

2010-09-01 00:00:00

pages

126-129

issue

3

eissn

1759-7706

issn

1759-7714

journal_volume

1

pub_type

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