Early-onset interstitial pneumonitis in a patient with advanced non-small cell lung cancer treated with crizotinib and osimertinib.

Abstract:

:Both crizotinib and osimertinib have been reported to have an adverse effect of interstitial pneumonitis in the treatment of non-small cell lung cancer (NSCLC). Here, we report the case of a 60-year-old male patient with advanced NSCLC resistant to osimertinib. Crizotinib was administered in combination with osimertinib due to elevated mesenchymal epithelial transition (MET) copy number amplification. However, early-onset interstitial pneumonitis occurred within two days.

journal_name

Thorac Cancer

journal_title

Thoracic cancer

authors

Cheng Y,Yu Q,Xiong Y,Guo C,Nie L

doi

10.1111/1759-7714.13785

subject

Has Abstract

pub_date

2021-01-12 00:00:00

eissn

1759-7706

issn

1759-7714

pub_type

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