Abstract：
:This study tested the role of affect lability and disinhibition in mediating associations between PTSD symptoms and two forms of alcohol-related problems, dependence syndrome symptoms (e.g., impaired control over consumption) and conduct problems (e.g., assault, risk behaviors). Genotype at the serotonin transporter linked polymorphic region (5-HTTLPR) was hypothesized to moderate associations between traumatic stress and PTSD symptoms. In addition, the study tested whether childhood traumatic stress moderated associations between combat trauma and PTSD symptoms. Participants were 270 OIF/OEF/OND veterans. The hypothesized model was largely supported. Participants with the low expression alleles of 5-HTTLPR (S or LG) exhibited stronger associations between childhood (but not combat) traumatic stress and PTSD symptoms. Affect lability mediated the associations between PTSD symptoms and alcohol dependence symptoms. Behavioral disinhibition mediated associations between PTSD symptoms and conduct related problems. Conditional indirect effects indicated stronger associations between childhood traumatic stress and lability, behavioral disinhibition, alcohol consumption, AUD symptoms, and associated conduct problems via PTSD symptoms among those with the low expression 5-HTTLPR alleles. However, interactions between combat trauma and either childhood trauma or genotype were not significant. The results support the hypothesis that affect lability and behavioral disinhibition are potential intermediate traits with distinct associations with AUD and associated externalizing problems.
journal_name
Addict Behavjournal_title
Addictive behaviorsauthors
Simons JS,Simons RM,O'Brien C,Stoltenberg SF,Keith JA,Hudson JAdoi
10.1016/j.addbeh.2016.08.044subject
Has Abstractpub_date
2017-01-01 00:00:00pages
185-193eissn
0306-4603issn
1873-6327pii
S0306-4603(16)30325-2journal_volume
64pub_type
杂志文章abstract：:The purpose of this study was to identify cultural, social, and intrapersonal factors associated with tobacco, alcohol, and illicit drug use among students attending dropout prevention/recovery high schools. Four mutually exclusive categories of substance use were used as outcome measures, and religiosity, educational...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/s0306-4603(99)00006-4
更新日期：2000-01-01 00:00:00
abstract：:The aim of this study was to examine the effectiveness of low-magnitude behavioral incentives in improving attendance for abstinence-treated patients and sustaining illicit-drug abstinence for methadone-treated patients. Subjects were randomly assigned to either incentive or control conditions, with target behaviors d...
journal_title：Addictive behaviors
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0306-4603(98)00119-1
更新日期：2000-03-01 00:00:00
abstract：:The purpose of this paper is to provide fundamental information about individual subject smoking behavior when the behavior is characterized as an event time-series. Each subject's smoking series revealed a characteristic inter-cigarette interval frequency distribution but there was little evidence of sequential depen...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/0306-4603(82)90053-3
更新日期：1982-01-01 00:00:00
abstract：:Skin conductance activity was monitored in male and female smokers and non-smokers during repeated presentation of high intensity auditory stimuli. Smokers, and, in particular, female smokers, exhibited significantly higher resting skin conductance levels and significantly larger skin conductance responses. The result...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/0306-4603(84)90057-1
更新日期：1984-01-01 00:00:00
abstract：BACKGROUND:American Indian/Alaskan Native (AI/AN) communities are second only to White Americans in mortality from opioid use disorder (OUD), while the smallest racial/ethnic minority population group in the USA. Those in rural communities experience significant health care disparities, including poorer treatment acces...
journal_title：Addictive behaviors
pub_type： 杂志文章,评审
doi：10.1016/j.addbeh.2020.106743
更新日期：2021-03-01 00:00:00
abstract：:The objective of the present study was to examine the properties of a modification of the Fagerström Test of Nicotine Dependence in a large sample of smokeless tobacco (ST) users. The subjects for this study included 256 males who were recruited for a tobacco cessation intervention that involved a visit with a dentist...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2007.01.005
更新日期：2007-09-01 00:00:00
abstract：:In France, since 1996, any general practitioner (GP) can prescribe high-dosage buprenorphine maintenance treatment (BMT) for opioid-dependent patients. The health authorities initially provided mandatory specific training, but since 1998, such training is only delivered by specialized networks and the pharmaceutical i...
journal_title：Addictive behaviors
pub_type： 杂志文章,多中心研究
doi：10.1016/j.addbeh.2004.04.019
更新日期：2005-01-01 00:00:00
abstract：:The present investigation sought to evaluate the unique explanatory relevance of pain-related anxiety in relation to negative and positive reinforcement smoking outcome expectancies among 135 (40.7% female; M(age) = 26.11, SD = 11.23) adult daily cigarette smokers. As predicted, pain-related anxiety was significantly ...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2010.01.005
更新日期：2010-06-01 00:00:00
abstract：:This study examined perceived risks and prevalence of alcohol, tobacco, and illicit drug use among ethnic groups of Whites, Blacks, and Hispanics; compared the extent to which drug use varied among different ethnic groups; explored whether or not there were any age and gender differences in drug use among the ethnic g...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/s0306-4603(99)00070-2
更新日期：2000-05-01 00:00:00
abstract：BACKGROUND:Alcohol use may be a coping mechanism for the stressors related to forced displacement. The aim of this study was to investigate levels and determinants of alcohol disorder amongst internally displaced persons (IDPs) in northern Uganda. METHODS:A cross-sectional survey with 1206 adult IDPs was conducted in ...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2011.03.006
更新日期：2011-08-01 00:00:00
abstract：INTRODUCTION:Romantic partners are crucial to successful smoking cessation, but the mechanisms by which partners influence cessation is unclear. Research in this area has focused heavily on partner smoking status and support for quitting, but partner influence may not be limited to these two constructs. The current stu...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2018.08.026
更新日期：2019-01-01 00:00:00
abstract：:Previous research has not compared implicit affective responses to smoking-related stimuli in occasional (i.e., those who smoke less than one cigarette per day) and daily smokers (i.e., those who smoke at least once per day). In addition to assessing their motivations for smoking, implicit affective responses were mea...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2011.10.006
更新日期：2012-03-01 00:00:00
abstract：:This study assessed the relationships between alcohol use and smoking cessation in a general population sample (N = 2115) of adults living in a county in north Florida. Nearly half of the sample had ever smoked. Of these, 44% had successfully quit; 34% had tried unsuccessfully to quit; 21% reported never having tried ...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/0306-4603(90)90063-4
更新日期：1990-01-01 00:00:00
abstract：:The commodity model of social support and features of Nondirective Support may clarify varied results of support interventions for smoking cessation. A commodity model views social support as attractive in and of itself and as an alternative to high-risk choices such as smoking. If such support is easily accessible, a...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/s0306-4603(97)00064-6
更新日期：1997-11-01 00:00:00
abstract：:Fifth and sixth grade children randomly assigned to experimental and control groups saw videotaped television programs in which the drinking of alcoholic beverages by the principal characters appeared in the experimental condition but not the control condition. Parents' drinking and home television watching were simil...
journal_title：Addictive behaviors
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0306-4603(86)90012-2
更新日期：1986-01-01 00:00:00
abstract：BACKGROUND:Age of onset is an important factor in the development and trajectory of psychiatric disorders; however, little is known regarding the age of onset in relation to disordered gambling in treatment seeking samples in the UK. Utilising a large residential treatment seeking gambler cohort, the current study exam...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2019.05.013
更新日期：2019-10-01 00:00:00
abstract：:Although alcohol expectancies have been shown to be consistently related to drinking and problematic drinking among underage youth, some studies suggest that they are more predictive of quantity than of frequency of drinking. However, this hypothesis has not been formally tested. This study examines the differential p...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/0306-4603(94)90007-8
更新日期：1994-09-01 00:00:00
abstract：:The Forbidden Food Survey is an instrument that was designed for use with eating disordered individuals. The first experiment in this study includes a description of the Forbidden Food Survey and the reliability and internal consistency of its scales. The second investigation examined the discriminant validity of the ...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/0306-4603(88)90053-6
更新日期：1988-01-01 00:00:00
abstract：:An intrinsic-extrinsic model of motivation for smoking cessation is extended to a population-based sample of smokers (N = 1,137), using a previously validated Reasons for Quitting (RFQ) scale. Psychometric evaluation of the RFQ replicated the model that includes health concerns and self-control as intrinsic motivation...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/s0306-4603(97)00059-2
更新日期：1997-11-01 00:00:00
abstract：:Sixty-one consecutive clients in a multidrug addiction detoxification and counselling unit were interviewed by their medical counsellor about bodily pain, distress, and coherence in their life. Clients who did not complete the 3-week postdetoxification program reported a higher level of fatigue and difficulties with c...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/s0306-4603(97)00012-9
更新日期：1998-01-01 00:00:00
abstract：:Although Gamblers Anonymous (GA) is a popular intervention for gamblers, many attendees later present for professional treatment. This study evaluated gambling and psychosocial problems in individuals seeking professional treatment for gambling and compared those with and without a history of GA attendance. At intake ...
journal_title：Addictive behaviors
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0306-4603(02)00233-2
更新日期：2003-08-01 00:00:00
abstract：AIMS:This study estimated the extent of familial alcohol supply in 45 low and middle income countries (LMIC), and examined the country-level effects of familial alcohol supply on adolescents' alcohol use. METHOD:We used data from 45 LMICs that participated in the Global School-Based Student Health Survey (GSHS) betwee...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2018.04.014
更新日期：2018-09-01 00:00:00
abstract：:A group of 35 alcoholics who indicated they had symptoms of phobia, panic, or both (the anxiety problem group) were compared to their matched controls who did not indicate having anxiety problems. Comparisons of relapse rates, reasons for relapse, and rates of emotional problems at six months posttreatment were made. ...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/0306-4603(92)90048-z
更新日期：1992-01-01 00:00:00
abstract：:Exposure to interpersonal victimization during childhood and adolescence is prevalent and has been found to be associated with negative physical and mental health outcomes. The present study examined the relations between childhood violence exposure and mental health on subsequent exposure to new physical assault in y...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2011.03.008
更新日期：2011-08-01 00:00:00
abstract：INTRODUCTION:Young adults' e-cigarette use is associated with perceptions that e-cigarettes are less harmful or addictive than cigarettes, socially acceptable, and appealing. This study developed and tested vaping educational messages addressing these factors: 1) Harm Perceptions, 2) Addictiveness, 3) Social Use, and 4...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2020.106778
更新日期：2021-04-01 00:00:00
abstract：INTRODUCTION:This study evaluated the cue-reactivity and several psychometric properties of a questionnaire designed to assess marijuana users' self-efficacy to employ 21 specific cognitive-behavioral strategies to reduce their marijuana use. METHOD:Using a web-based recruitment and data-collection procedure, 513 regu...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2014.07.005
更新日期：2014-12-01 00:00:00
abstract：:The goal of this article is to describe models to examine change over time with an outcome that represents a count, such as the number of alcoholic drinks per day. Common challenges encountered with this type of data are: (1) the outcome is discrete, may have a large number of zeroes, and may be overdispersed, (2) the...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2018.09.016
更新日期：2019-07-01 00:00:00
abstract：INTRODUCTION:Parental monitoring and family relations are recognized as protective factors for youth alcohol use. The purpose of this study was to investigate perceived parental monitoring and family relations among subgroups of Mexican youths with different patterns of drinking behaviors and consequences. METHODS:A l...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2015.07.025
更新日期：2015-12-01 00:00:00
abstract：:Few studies have examined the psychosocial aspects of tobacco smoking in young adults, particularly among alternative forms such as waterpipe. To address this gap, we examined the association of psychosocial characteristics (i.e., sociodemographics, risk perception, social norms, and pluralistic ignorance) with waterp...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2008.07.017
更新日期：2008-12-01 00:00:00
abstract：AIMS:To describe neurocognitive function among opioid-dependent adults seeking buprenorphine treatment and to explore the impact of lifetime psychiatric conditions on neurocognitive function. To explore the additive interaction of patient-based characteristics that may help to inform treatment. DESIGN:Cross-sectional ...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2016.03.018
更新日期：2016-09-01 00:00:00
