A multiplayer game: species of Clostridium, Acinetobacter, and Pseudomonas are responsible for the persistence of antibiotic resistance genes in manure-treated soils.

Abstract:

:Antibiotics are routinely used in modern livestock farming. The manure from medicated animals is used for the fertilization of arable crops, which in turn leads to the accumulation of antibiotic resistance genes (ARGs) in the environment. This is a potentially serious public health issue, yet the identities of the bacterial taxa involved in ARG persistence are as yet undetermined. Using soil-manure microcosm experiments, we investigated the relationship between (i) the persistence of diverse ARGs and (ii) the dynamics of bacterial community members. We were able to identify, for the first time, the bacterial taxa involved in ARG enrichment in manured soils. They were gut-associated Clostridium species, and environmental species of Acinetobacter and Pseudomonas genera, all of them closely related to important nosocomial pathogens. Our data provide new clues on the routes by which ARGs may spread from farms to medical clinics.

journal_name

Environ Microbiol

authors

Leclercq SO,Wang C,Sui Z,Wu H,Zhu B,Deng Y,Feng J

doi

10.1111/1462-2920.13337

subject

Has Abstract

pub_date

2016-10-01 00:00:00

pages

3494-3508

issue

10

eissn

1462-2912

issn

1462-2920

journal_volume

18

pub_type

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