Abstract:
OBJECTIVES:To evaluate current evidence of the effectiveness of botulinum toxin (BTX) injection for lower limbs spasticity after stroke. METHODS:Ovid MEDLINE(R) In-Process and Other Non-Indexed Citations,Ovid MEDLINE(R), Ovid EMBASE, Web of Science, and PubMed (NLM) from database were searched inception through Week 23, 2015. Randomized controlled trials (RCTs) comparing the clinical efficacy of BTX injection to placebo or conventional therapy on lower limbs spasticity after stroke were included. We constructed random effects models and calculated mean difference (MD) or standardized mean difference (SMD) for continuous outcomes. RESULTS:One thousand three hundred and forty-three records were identified and among them 7 articles (603 patients) were eligible for the final analysis. A statistically significant decrease in muscle tone was observed at week 4 and 12 after injection (Subgroup analysis, SMD = 0.85, 95% CI: 0.2-1.5; p = 0.001; I(2) = 81% and SMD = 0.42, 95% CI: 0.07-0.77; p = 0.02; I(2) = 45%, respectively). Patients who received in BTX therapy were likely to have significant increased Fugl-Meyer score than control group with MD = 3.19 (95% CI: 0.22-6.16, p = 0.04, I(2) = 96%). There was no difference in gait speed between two groups during whole follow-up period. CONCLUSION:BTX showed more persistent clinical benefits in lower limbs spasticity and Fugl-Meyer score than placebo in patients after stroke. These results suggest that BTX could be a useful and safety strategy for the treatment of lower limbs spasticity after stroke. Further investigation is required to determine the effectiveness of BTX injection for stroke patients with optimal timing and dose of intervention.
journal_name
Top Stroke Rehabiljournal_title
Topics in stroke rehabilitationauthors
Wu T,Li JH,Song HX,Dong Ydoi
10.1080/10749357.2016.1139294subject
Has Abstractpub_date
2016-06-01 00:00:00pages
217-23issue
3eissn
1074-9357issn
1945-5119journal_volume
23pub_type
杂志文章,meta分析,评审abstract::Objectives The sit to stand (STS) movement is key to independence and commonly affected by stroke. Repetitive practice is likely to improve STS ability during rehabilitation, however current practice levels are unknown. The objective of this study was simply to count the number of STS movements performed during the re...
journal_title:Topics in stroke rehabilitation
pub_type: 杂志文章,随机对照试验
doi:10.1080/10749357.2017.1374687
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:Providing appropriate and effective information to people with stroke and their families has been identified as a key component to successful practice. Researchers continue to focus on "lack of information" as being the lack of specific technical medical information rather than the communication of practical...
journal_title:Topics in stroke rehabilitation
pub_type: 杂志文章
doi:10.1310/NPC4-01YV-P66Q-VM9R
更新日期:2004-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Complex regional pain syndrome type I (CPRS I), is a complex of symptoms characterized by diffuse pain usually with associated swelling, vasomotor instability, and severe functional impairment of the affected extremity in stroke patients. Pain is a prominent feature and is often refractory to var...
journal_title:Topics in stroke rehabilitation
pub_type: 杂志文章,随机对照试验
doi:10.1179/1074935714Z.0000000025
更新日期:2015-08-01 00:00:00
abstract::Intrathecal baclofen (ITB) therapy is a widely recognized management technique for severe, disabling spasticity in individuals with cerebral palsy and spinal and brain injuries. Its utility in the stroke population has only been recognized recently. Unlike the aforementioned patient populations, many stroke survivors ...
journal_title:Topics in stroke rehabilitation
pub_type: 杂志文章
doi:10.1310/14PN-TV5C-AYUB-NDP2
更新日期:2001-04-01 00:00:00
abstract::Stroke is the leading cause of disability in older Americans. Each year 750,000 Americans suffer a stroke, two thirds of whom are left with neurological deficits that persistently impair function. Principal among them is hemiparetic gait that limits mobility and increases fall risk, promoting a sedentary lifestyle. Th...
journal_title:Topics in stroke rehabilitation
pub_type: 杂志文章,评审
doi:10.1310/PJQN-KAN9-TTVY-HYQH
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND:Balance is a common mobility limitation following stroke, but determination of the most effective balance-related plan of care can be difficult due to multiple balance impairments that vary between individuals. The Brief-BESTest is a validated outcome measure for balance based on six systems of postural cont...
journal_title:Topics in stroke rehabilitation
pub_type: 杂志文章
doi:10.1080/10749357.2018.1517493
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:The similarities or differences of the three some (physiotherapists, patients, and caregivers) thought about the process of stroke rehabilitation can play a key role in the success of rehabilitation. OBJECTIVE:The aim of this qualitative study was to investigate the perspectives of the three some, with rega...
journal_title:Topics in stroke rehabilitation
pub_type: 杂志文章
doi:10.1179/1074935714Z.0000000042
更新日期:2015-10-01 00:00:00
abstract:PURPOSE:Hope is said to be important in recovery from illness or injury, supporting adjustment, perseverance, and positive outcomes. There has been little exploration of hope in people after stroke. This is reflected in the literature, which lacks consistent definition and terminology. This purpose of this article is t...
journal_title:Topics in stroke rehabilitation
pub_type: 杂志文章,评审
doi:10.1310/tsr1805-490
更新日期:2011-09-01 00:00:00
abstract:PURPOSE:Education is a key component of post stroke care, but patients and carers often report dissatisfaction with information provided. A small number of studies have reported challenges surrounding the provision of information to this population, but patients' perspectives have not been explored in detail. The aim o...
journal_title:Topics in stroke rehabilitation
pub_type: 杂志文章
doi:10.1310/tsr1702-69
更新日期:2010-03-01 00:00:00
abstract:BACKGROUND:Several reports have focused on the effects of whole body vibration (WBV) on spasticity with differing results. Most studies used modified Ashworth scale (MAS) for qualitative measurements, but the effect was small. OBJECTIVE:To investigate the effect of WBV on spasticity in hemiplegic legs of patients with...
journal_title:Topics in stroke rehabilitation
pub_type: 杂志文章
doi:10.1080/10749357.2017.1389055
更新日期:2018-03-01 00:00:00
abstract:INTRODUCTION:Stroke is the leading cause of disability. A need exists for an effective intervention to enhance upper extremity (UE) motor abilities and activities of daily living (ADL) performance. OBJECTIVE:The objectives of this pilot study were to (1) determine the feasibility of adding Interactive Metronome (IM) t...
journal_title:Topics in stroke rehabilitation
pub_type: 临床试验,杂志文章
doi:10.1310/tsr1806-728
更新日期:2011-11-01 00:00:00
abstract::The purpose of this article is to present the Kinesio taping method used to improve the upper extremity function in the adult with hemiplegia. The article discusses various therapeutic methods used in the treatment of stroke patients to achieve a functional upper extremity. The only taping technique for various upper ...
journal_title:Topics in stroke rehabilitation
pub_type: 杂志文章,评审
doi:10.1310/33KA-XYE3-QWJB-WGT6
更新日期:2006-07-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Studies suggest that family caregiver well-being (ie, depressive symptoms and life satisfaction) may affect stroke survivor depressive symptoms. We used mediation analysis to assess whether caregiver well-being might be a factor explaining stroke survivor depressive symptoms, after controlling fo...
journal_title:Topics in stroke rehabilitation
pub_type: 杂志文章
doi:10.1310/tsr2001-44
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:Dynamic lycra splints are proposed to modify hypertonicity due to their characteristics - neutral warmth, circumferential pressure, and creating a low-intensity prolonged stretch on hypertonic muscles - to contribute to increased sensory awareness of the involved limb. OBJECTIVES:The aim of this study was t...
journal_title:Topics in stroke rehabilitation
pub_type: 杂志文章,随机对照试验
doi:10.1080/10749357.2019.1704371
更新日期:2020-09-01 00:00:00
abstract:BACKGROUND:Against the background of linguistic and cultural differences, there is a need for translation and adaptation from the English version of the Fugl-Meyer Assessment (FMA) to Japanese. In addition, there is no study of inter-rater reliability of FMA all domains for affected upper extremities with appropriate s...
journal_title:Topics in stroke rehabilitation
pub_type: 杂志文章
doi:10.1080/10749357.2018.1484987
更新日期:2018-10-01 00:00:00
abstract:OBJECTIVES:Visual field defects due to hemi- or quadrantanopia after stroke represent an under-recognized neurological symptom with inefficient instruments for neurorehabilitation to date. We here examined the effects of training in a virtual reality (VR) supermarket on cognitive functions, depressive symptoms, and sub...
journal_title:Topics in stroke rehabilitation
pub_type: 杂志文章
doi:10.1080/10749357.2020.1716531
更新日期:2020-09-01 00:00:00
abstract::The privileging of the substituted judgment standard as the gold standard for surrogate decision making in law and bioethics has constrained the research agenda in end-of-life decision making. The empirical literature is inundated with a plethora of "Newlywed Game" designs, in which potential patients and potential su...
journal_title:Topics in stroke rehabilitation
pub_type: 杂志文章
doi:10.1310/tsr1404-80
更新日期:2007-07-01 00:00:00
abstract::Background. Motor imagery (MI) consists of the mental simulation of repetitive movements with the intention of promoting the learning of a motor skill. It seems to be an additional useful tool for motor-based therapy to potentiate the rehabilitation of the upper limb function of post-stroke individuals. Objective. To ...
journal_title:Topics in stroke rehabilitation
pub_type: 杂志文章
doi:10.1080/10749357.2019.1627716
更新日期:2019-10-01 00:00:00
abstract::Although reported frequencies vary due to study design, patient characteristics, and method of ascertainment, dysphagia is a commonly encountered morbidity after stroke. Consequently, speech-language pathologists' clinical caseloads are heavily populated with individuals with poststroke dysphagia. The body of knowledg...
journal_title:Topics in stroke rehabilitation
pub_type: 杂志文章
doi:10.1310/tsr1802-120
更新日期:2011-03-01 00:00:00
abstract::Stroke onset causes disruption of family roles as caregiving tasks are assumed. The current study presents a qualitative and quantitative analysis of the problems of 123 older, spousal stroke caregivers. Problems were coded into 14 categories; frequencies of occurrence and difficulty were also analyzed. Differences in...
journal_title:Topics in stroke rehabilitation
pub_type: 杂志文章
doi:10.1310/DDBP-TRCC-3KVA-4B94
更新日期:2002-04-01 00:00:00
abstract::The Medicare Modernization Act of 2003 (MMA'03) did more than introduce a prescription drug benefit for Medicare beneficiaries; it also laid the groundwork for several far-reaching changes in the Medicare program. These changes must be considered in the context of the "American devolution"--a much larger shift in Amer...
journal_title:Topics in stroke rehabilitation
pub_type: 杂志文章
doi:10.1310/R28D-5XJQ-B0TX-R4VM
更新日期:2005-04-01 00:00:00
abstract:OBJECTIVES:In India, post-stroke outcomes are determined using functional outcome measures (FOMs), the contents of which have not been validated for their relevance to the Indian population. In this study, we aimed to evaluate the cultural validity of five frequently used stroke-specific FOMs by comparing their content...
journal_title:Topics in stroke rehabilitation
pub_type: 杂志文章
doi:10.1080/10749357.2016.1234190
更新日期:2017-04-01 00:00:00
abstract::Poststroke somatosensory impairment is prevalent, yet commonly used clinical measures lack the sensitivity needed to quantify impairment and detect change due to intervention. This selective review, prepared and presented as a part of the I-Treat Conference (June 22, 2013, Columbus, Ohio), discusses the prevalence of ...
journal_title:Topics in stroke rehabilitation
pub_type: 杂志文章,评审
doi:10.1310/tsr2104-290
更新日期:2014-07-01 00:00:00
abstract:OBJECTIVES:To assess the use of extracorporeal shock wave therapy (ESWT) for the treatment of equinus foot after stroke and to correlate the ESWT effect on spastic plantar-flexor muscles with echo intensity on the Heckmatt scale. METHODS:The prospective open-label study examined 23 patients with poststroke lower limb ...
journal_title:Topics in stroke rehabilitation
pub_type: 临床试验,杂志文章
doi:10.1310/tsr21S1-S17
更新日期:2014-01-01 00:00:00
abstract::The required course for freshmen in Northwestern University's engineering school - a 2-quarter sequence called Engineering Design and Communication (EDC) - is noteworthy not only for its project-based focus on user-centered design, but also for its innovative integrated approach to teaching communication, teamwork, an...
journal_title:Topics in stroke rehabilitation
pub_type: 杂志文章
doi:10.1310/tsr1804-361
更新日期:2011-07-01 00:00:00
abstract:PURPOSE:The rehabilitation of patients who are recovering from severe stroke is associated with a substantial use of resources but limited potential for functional improvement. As a result, these individuals are not perceived as being ideal candidates for inpatient stroke rehabilitation. The objective of this review wa...
journal_title:Topics in stroke rehabilitation
pub_type: 杂志文章,评审
doi:10.1310/tsr1902-122
更新日期:2012-03-01 00:00:00
abstract:OBJECTIVE:The clinical functional evaluation is the usual method for dysphagia screening in patients with acute stroke. This study compared two methods of evaluation--with liquid and semisolid viscosities. METHOD:Twenty-six patients with stroke onset within 7 days--with a mean age of 63.5 +/- 12.4 years--were prospect...
journal_title:Topics in stroke rehabilitation
pub_type: 临床试验,杂志文章
doi:10.1310/tsr1504-378
更新日期:2008-07-01 00:00:00
abstract::Background: Neuropsychiatric symptoms are common after stroke and are distressing symptoms. They may persist after the acute event and negatively impact rehabilitation, functioning, and patients' quality of life. Objectives: To elucidate the prevalence and course of neuropsychiatric symptoms in stroke patients during ...
journal_title:Topics in stroke rehabilitation
pub_type: 杂志文章
doi:10.1080/10749357.2020.1871283
更新日期:2021-01-10 00:00:00
abstract:BACKGROUND:The effects of whole body vibration (WBV) on chronic stroke (CS) patients have been investigated by some previous studies. However, controversy still exists. OBJECTIVE:The objective of this meta-analysis was to review existing studies that assess the effects of WBV training on CS patients. METHODS:We searc...
journal_title:Topics in stroke rehabilitation
pub_type: 杂志文章,meta分析,评审
doi:10.1179/1074935714Z.0000000005
更新日期:2015-06-01 00:00:00
abstract:BACKGROUND:In recent years the Trunk Impairment Scale version 2.0 (TIS 2.0) has been a frequently used scale to assess dynamic sitting balance and trunk control for stroke patients. OBJECTIVE:To translate the TIS 2.0 into Spanish and validate it as an instrument to evaluate dynamic sitting balance and trunk control an...
journal_title:Topics in stroke rehabilitation
pub_type: 杂志文章
doi:10.1080/10749357.2016.1151662
更新日期:2016-08-01 00:00:00