Abstract：
INTRODUCTION:Cue-reactivity is thought to play a fundamental role in the maintenance of addiction. The incentive sensitization theory proposes that conditioned responses are related to increased sensitivity of the reward-related dopaminergic pathways in the brain. However, neuroimaging studies on alcohol cue-reactivity show inconsistent results. METHODS:Stimuli content of 26 alcohol cue-reactivity studies was systematically reviewed. RESULTS:No differences were found between alcoholic beverage stimuli and non-alcoholic beverage stimuli in human display and brand factors; however, alcoholic beverage stimuli were more likely to display social interaction compared to non-alcoholic beverage stimuli. CONCLUSIONS:Given that processing of social information activates brain areas that partly overlap with reward-related brain areas associated with cue-reactivity, such differences between conditions can introduce noise in the findings. We therefore suggest matching stimuli sets on the reviewed factors carefully to improve reliability of neuroimaging studies investigating alcohol-related cue-reactivity.
journal_name
Addict Behavjournal_title
Addictive behaviorsauthors
Groefsema M,Engels R,Luijten Mdoi
10.1016/j.addbeh.2016.02.033subject
Has Abstractpub_date
2016-07-01 00:00:00pages
123-8eissn
0306-4603issn
1873-6327pii
S0306-4603(16)30067-3journal_volume
58pub_type
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