Developmental changes in serotonin signaling: Implications for early brain function, behavior and adaptation.

abstract：:A small surgical lesion of the parietal cortex induces an increase in the expression of several messenger RNAs varying from 172 to 980% in the entire homolateral cerebral cortex, as detected by quantitative in situ hybridization histochemistry. The messenger RNAs encoding the immediate early genes of the leucine zippe...

journal_title：Neuroscience

authors： Jacobs O,Van Bree L,Mailleux P,Zhang F,Schiffmann SN,Halleux P,Albala N,Vanderhaeghen JJ

更新日期：1994-04-01 00:00:00

abstract：:An antibody recognizing all ankyrin isoforms was employed to localize ankyrin in the cerebellum by light and electron microscopy. White matter (myelinated fiber tracts) did not contain ankyrin. Granule cell bodies and axons contained ankyrin which extended into the parallel fibers and their synapses. Purkinje cells co...

journal_title：Neuroscience

authors： Babitch JA

更新日期：1993-06-01 00:00:00

abstract：:Intracerebroventricular (i.c.v.) injection of kynurenic acid (KYNA) had sedative and hypnotic effects during stress in neonatal chicks. However, its mechanism has not been clarified. KYNA is an endogenous antagonist of the α7 nicotinic acetylcholine (α7nACh) receptor and N-methyl-d-aspartate (NMDA) receptor. Therefore...

journal_title：Neuroscience

authors： Yoshida J,Shigemura A,Ogino Y,Denbow DM,Furuse M

更新日期：2013-09-17 00:00:00

abstract：:Neurons in rat medulla oblongata with Fos immunoreactivity as a marker of synaptic excitation evoked by pentylenetetrazole-induced seizures were compared with cell populations activated by the stimulation of chemoreceptor and baroreceptor afferent pathways. Chemoreceptors were stimulated by placing rats in a hypoxic g...

journal_title：Neuroscience

authors： Kanter RK,Strauss JA,Sauro MD

更新日期：1996-08-01 00:00:00

abstract：:Cerebral hypoxia may be the main component of cell damage caused by ischemia. Previous studies demonstrated a neuroprotective effect of early hyperbaric oxygen (HBO) treatment in various animal models of focal cerebral ischemia. Neuropathologic study showed that exposure of HBO may prevent cell death in ischemic corte...

journal_title：Neuroscience

authors： Lou M,Zhang H,Wang J,Wen SQ,Tang ZQ,Chen YZ,Yan WQ,Ding MP

更新日期：2007-05-11 00:00:00

abstract：:The participation of excitatory neurotransmitter systems in the basal ganglia in the initiation and propagation of limbic seizures induced by pilocarpine has been investigated in the rat. Limbic seizures (electrographic and motor) occur in rats receiving bilateral microinjections into the entopeduncular nucleus of 12....

journal_title：Neuroscience

authors： Patel S,De Sarro GB,Meldrum BS

更新日期：1988-12-01 00:00:00

abstract：:The interactions between the cannabinoid and opioid systems for pain modulation are reciprocal. However, the role and the importance of the cannabinoid system in the antinociceptive effects of opioids remain uncertain. We studied these interactions with the goal of highlighting the involvement of the cannabinoid syste...

journal_title：Neuroscience

authors： Desroches J,Bouchard JF,Gendron L,Beaulieu P

更新日期：2014-03-07 00:00:00

abstract：:A systematic line-sampling method is described for counting and mapping myelinated axons in transverse sections of the spinal cord. Its advantages over random sampling of small areas are considered. The technique was applied to quantifying experimental weight-drop contusion injuries of cat spinal cord, from several mo...

journal_title：Neuroscience

authors： Blight AR

更新日期：1983-10-01 00:00:00

abstract：:Limb somatosensory signals modify the discharge of vestibular neurons and elicit postural reflexes, which stabilize the body position. The aim of this study was to investigate the contribution of the γ-amino-butyric-acid (GABA) to the responsiveness of vestibular neurons to somatosensory inputs. The activity of 128 ve...

journal_title：Neuroscience

authors： Grasso C,Li Volsi G,Cataldo E,Manzoni D,Barresi M

更新日期：2016-10-29 00:00:00

abstract：:Immunosuppression remains a key issue in neural transplantation. Systemic administration of cyclosporin-A is currently widely used but has many severe adverse side effects. Newer immunosuppressive agents, such as tacrolimus (TAC) and rapamycin (RAPA), have been investigated for their neuroprotective properties on dopa...

journal_title：Neuroscience

authors： Alemdar AY,Sadi D,McAlister V,Mendez I

更新日期：2007-04-25 00:00:00

abstract：:Activation of neural stem/progenitor cells (NSPCs) is a potential therapeutic strategy of neurological disorders. In this study, NSPCs of subventricular zone were isolated and cultured from platelet-derived growth factor-β-receptor-knockout (PDGFR-β(-/-)) mice of postnatal day 1 (P1) and P28, and the roles of PDGFR-β ...

journal_title：Neuroscience

authors： Xu G,Shen J,Ishii Y,Fukuchi M,Dang TC,Zheng Y,Hamashima T,Fujimori T,Tsuda M,Funa K,Sasahara M

更新日期：2013-05-15 00:00:00

abstract：:People commonly synchronize taps to rhythmic sounds and can continue tapping after the sounds stop, indicating that time intervals between sounds can be internalized. Here, we investigate what happens in the brain after simply listening to auditory beats in order to understand more about the automatic internalization ...

journal_title：Neuroscience

authors： Graber E,Fujioka T

更新日期：2019-08-10 00:00:00

abstract：:The tectofugal pathway in birds consists of four stations, the retina, optic tectum, rotundal nucleus, and entopallium, and it conveys visual information via three ascending pathways. These pathways consist of retino-tectal, tecto-rotundal and rotundo-entopallial cells, all of which are glutamatergic. The present stud...

journal_title：Neuroscience

authors： Atoji Y

更新日期：2016-03-01 00:00:00

abstract：:Microinjections of the neuroexcitatory substance L-glutamate, were made directly into various laminae of trigeminal nucleus caudalis to examine the influence of medullary dorsal horn neurons on the adrenal secretion of catecholamines in the anesthetized cat. Microinjections into the marginal layers (lamina I-II) or in...

journal_title：Neuroscience

authors： Bereiter DA,Gann DS

更新日期：1988-05-01 00:00:00

abstract：:The unilateral application of GABA (10(-5) M; 30 min) into thalamic motor nuclei of the cat increases the release of dopamine in both caudate nuclei. This effect has been suggested to be related to an activation of the bilateral corticostriatal glutamatergic projection, glutamate exerting a presynaptic facilitatory in...

journal_title：Neuroscience

authors： Barbeito L,Girault JA,Godeheu G,Pittaluga A,Glowinski J,Cheramy A

更新日期：1989-01-01 00:00:00

abstract：:Hypofunction of the N-methyl-D-aspartic acid receptor (NMDAr) has been considered to play a crucial role in the pathophysiology of schizophrenia. In rodent electroencephalogram (EEG) studies, non-competitive NMDAr antagonists have been reported to produce aberrant basal gamma band oscillation (GBO), as observed in sch...

journal_title：Neuroscience

authors： Hiyoshi T,Kambe D,Karasawa J,Chaki S

更新日期：2014-11-07 00:00:00

abstract：:Dephosphorylation by the Ca2+/calmodulin-dependent phosphatase calcineurin has been suggested as an important mechanism of Ca2+-dependent inactivation of voltage-gated Ca2+ channels. We have tested whether calcineurin plays a role in the inactivation process of two types of high-voltage-activated Ca2+ channels (L and ...

journal_title：Neuroscience

authors： Zeilhofer HU,Blank NM,Neuhuber WL,Swandulla D

更新日期：2000-01-01 00:00:00

abstract：:We have shown that synaptosomal membrane Na+, K+-ATPase activity is stimulated or inhibited by norepinephrine according to the presence or absence of a brain soluble fraction. Gel filtration of such soluble fraction has allowed the separation of two fractions, peaks I and II, able to stimulate and inhibit Na+, K+-ATPa...

journal_title：Neuroscience

authors： Vatta M,Peña C,Fernández B,Rodríguez de Lores Arnaiz G

更新日期：1999-05-01 00:00:00

abstract：:Tenascin-C is an extracellular matrix glycoprotein involved in cell adhesion and migration, and neurite outgrowth. Since these processes have been found to be under thyroid control in the developing rat brain, we have investigated the effect of congenital hypothyroidism on tenascin-C expression. At birth, in situ hybr...

journal_title：Neuroscience

authors： Alvarez-Dolado M,González-Sancho JM,Bernal J,Muñoz A

更新日期：1998-05-01 00:00:00

abstract：:Several types of brain injuries have been associated with alterations in the striatal expression of neurotrophic factors, including glial cell line-derived neurotrophic factor (GDNF). However, contradictory results on the striatal expression of GDNF have been reported in different animal models of Parkinson's disease....

journal_title：Neuroscience

authors： Mertens B,Massie A,Michotte Y,Sarre S

更新日期：2009-08-04 00:00:00

abstract：:In a previous study, it was shown that populations of climbing fibers, derived from the inferior olivary complex (IOC) contain the peptide corticotropin releasing factor (CRF) and that the expression of this peptide in climbing fibers could be modulated by the level of activity in olivary afferents. The intent of this...

journal_title：Neuroscience

authors： Tian JB,King JS,Bishop GA

更新日期：2008-04-22 00:00:00

abstract：:Interleukin-1 plays an important role as mediator of endotoxin-induced responses in the brain such as fever, sleep, anorexia, behavioural and neuroendocrine changes. In the present study, interleukin-1 beta immunocytochemistry has been performed at the light and electron microscopic level to study the cellular and sub...

journal_title：Neuroscience

authors： Van Dam AM,Bauer J,Tilders FJ,Berkenbosch F

更新日期：1995-04-01 00:00:00

abstract：:Similarities in cellular morphology, afferentation, efferentation, and neurotransmitter content between the internal and external parts of the pallidum and the substantia nigra pars reticulata have long been noted. Here we present evidence that the globus pallidus, entopedunucular nucleus and substantia nigra pars ret...

journal_title：Neuroscience

authors： Sousa R,Hrinya Tannery N,Lafer EM

更新日期：1990-01-01 00:00:00

abstract：:Neural function within the medial prefrontal cortex (mPFC) regulates normal cognition, attention and impulse control, implicating neuroregulatory abnormalities within this region in mental dysfunction related to schizophrenia, depression and drug abuse. Both serotonin-2A (5-HT2A) and -2C (5-HT2C) receptors are known t...

journal_title：Neuroscience

authors： Nocjar C,Alex KD,Sonneborn A,Abbas AI,Roth BL,Pehek EA

更新日期：2015-06-25 00:00:00

abstract：:Flies acquire information about self-rotation via Coriolis forces detected by their moving halteres. Information processing in the haltere system was analysed by exploiting the method of simulating rotational stimuli by vibrating the fly's body and simultaneously observing compensatory head and wing reactions. Althoug...

journal_title：Neuroscience

authors： Nalbach G

更新日期：1994-07-01 00:00:00

abstract：:Perceptual integration of sensory input from our two nostrils has received little attention in comparison to lateralized inputs for vision and hearing. Here, we investigated whether a binary odor mixture of eugenol and l-carvone (smells of cloves and caraway) would be perceived differently if presented as a mixture in...

journal_title：Neuroscience

authors： Schütze M,Negoias S,Olsson MJ,Hummel T

更新日期：2014-01-31 00:00:00

abstract：:The morphochemical disposition of the adenylate cyclase-linked dopamine receptor (D1 type) in the rat striatum has been assessed at various time points after a neurotoxic lesion of the dopaminergic afferent pathway to the caudate nucleus. D1 receptor binding sites in the caudate nucleus were determined by in vitro aut...

journal_title：Neuroscience

authors： Ariano MA

更新日期：1989-01-01 00:00:00

abstract：:The process of valuation assists in determining if an object or course of action is rewarding. Delay discounting is the observed decay of a rewards' subjective value over time. Encoding the subjective value of rewards across a spectrum has been attributed to brain regions belonging to the valuation and executive contr...

journal_title：Neuroscience

authors： Loganathan K,Lv J,Cropley V,Ho ETW,Zalesky A

更新日期：2021-01-01 00:00:00

abstract：:The clinical course of the degenerative motor neuron disorder amyotrophic lateral sclerosis (ALS) is closely related to hypoxia. The normal response to hypoxia involves two pathways in particular: the hypoxia inducible factor 1α (HIF-1α) pathway (which notably controls the synthesis of vascular endothelial growth fact...

journal_title：Neuroscience

authors： Moreau C,Gosset P,Kluza J,Brunaud-Danel V,Lassalle P,Marchetti P,Defebvre L,Destée A,Devos D

更新日期：2011-01-13 00:00:00

abstract：:Bleomycin hydrolase (BLMH) is a multifaceted neutral cysteine protease with a suggested role in antigen presentation, homocysteine-thiolactone metabolism, and Alzheimer's disease pathogenesis. Deletion of the protease in mice results in increased neonatal mortality and dermatopathology. Immunohistochemical and behavio...

journal_title：Neuroscience

authors： Montoya SE,Thiels E,Card JP,Lazo JS

更新日期：2007-05-25 00:00:00