Abstract:
:Pest species represent a major ongoing threat to global biodiversity. Effective management approaches are required that regulate pest numbers, while minimizing collateral damage to nontarget species. The Trojan Female Technique (TFT) was recently proposed as a prospective approach to biological pest control. The TFT draws on the evolutionary hypothesis that maternally inherited mitochondrial genomes are prone to the accumulation of male, but not female, harming mutations. These mutations could be harnessed to provide trans-generational fertility-based control of pest species. A candidate TFT mutation was recently described in the fruit fly, Drosophila melanogaster, which confers male-only sterility in the specific isogenic nuclear background in which it is maintained. However, applicability of the TFT relies on mitochondrial mutations whose male-sterilizing effects are general across nuclear genomic contexts. We test this assumption, expressing the candidate TFT-mutation bearing haplotype alongside a range of nuclear backgrounds and comparing its fertility in males, relative to that of control haplotypes. We document consistently lower fertility for males harbouring the TFT mutation, in both competitive and noncompetitive mating contexts, across all nuclear backgrounds screened. This indicates that TFT mutations conferring reduced male fertility can segregate within populations and could be harnessed to facilitate this novel form of pest control.
journal_name
Evol Appljournal_title
Evolutionary applicationsauthors
Dowling DK,Tompkins DM,Gemmell NJdoi
10.1111/eva.12297subject
Has Abstractpub_date
2015-10-01 00:00:00pages
871-80issue
9issn
1752-4571journal_volume
8pub_type
杂志文章abstract::Individual assignment and genetic mixture analysis are commonly utilized in contemporary wildlife and fisheries management. Although microsatellite loci provide unparalleled numbers of alleles per locus, their use in assignment applications is increasingly limited. However, next-generation sequencing, in conjunction w...
journal_title:Evolutionary applications
pub_type: 杂志文章
doi:10.1111/eva.12606
更新日期:2018-03-11 00:00:00
abstract::Genomic methodologies offer unprecedented opportunities for statistically robust studies of species broadly distributed in environments conducive to high gene flow, providing valuable information for wildlife conservation and management. Here, we sequence restriction site-associated DNA to characterize genome-wide sin...
journal_title:Evolutionary applications
pub_type: 杂志文章
doi:10.1111/eva.12892
更新日期:2019-11-22 00:00:00
abstract::Evolutionary theory predicts that once an individual reaches an age of sufficiently low Darwinian fitness, (s)he will have reduced chances of keeping cancerous lesions in check. While we clearly need to better understand the emergence of precursor states and early malignancies as well as their mitigation by the microe...
journal_title:Evolutionary applications
pub_type: 杂志文章
doi:10.1111/eva.12033
更新日期:2013-01-01 00:00:00
abstract::Biological control is the main purpose of intentionally introducing non-native invertebrate species. The evolutionary changes that occur in the populations of the introduced biological control agents may determine the agent's efficiency and the environmental safety. Here, to explore the pattern and extent of potential...
journal_title:Evolutionary applications
pub_type: 杂志文章
doi:10.1111/eva.12774
更新日期:2019-02-11 00:00:00
abstract::Inbreeding depression (reduced fitness of individuals with related parents) has long been a major focus of ecology, evolution, and conservation biology. Despite decades of research, we still have a limited understanding of the strength, underlying genetic mechanisms, and demographic consequences of inbreeding depressi...
journal_title:Evolutionary applications
pub_type: 杂志文章,评审
doi:10.1111/eva.12414
更新日期:2016-10-23 00:00:00
abstract::Fisheries-induced evolution has been hypothesized to delay the recovery of collapsed fish stocks through effects on their productivity. The cod stock in the southern Gulf of St. Lawrence (SGSL) collapsed in the early 1990s and has shown no recovery since then, due mainly to high natural mortality of adult cod. Age and...
journal_title:Evolutionary applications
pub_type: 杂志文章
doi:10.1111/j.1752-4571.2010.00128.x
更新日期:2011-01-01 00:00:00
abstract::Marine protected areas (MPAs) are increasingly implemented worldwide to maintain and restore depleted populations. However, despite our knowledge on the myriad of positive responses to protection, there are few empirical studies on the ability to conserve species' mating patterns and secondary sexual traits. In male E...
journal_title:Evolutionary applications
pub_type: 杂志文章
doi:10.1111/eva.12992
更新日期:2020-05-22 00:00:00
abstract::The evolutionary rescue of host populations may prevent extinction from novel pathogens. However, the conditions that facilitate rapid evolution of hosts, in particular the population variation in host susceptibility, and the effects of host evolution in response to pathogens on population outcomes remain largely unkn...
journal_title:Evolutionary applications
pub_type: 杂志文章
doi:10.1111/eva.12568
更新日期:2017-11-20 00:00:00
abstract::Drought is one of the most important selection pressures for forest trees in the context of climate change. Yet, the different evolutionary mechanisms, and their environmental drivers, by which certain populations become more drought tolerant than others is still little understood. We studied adaptation to drought in ...
journal_title:Evolutionary applications
pub_type: 杂志文章
doi:10.1111/eva.13029
更新日期:2020-06-17 00:00:00
abstract::Salmon lice Lepeophtheirus salmonis are an ecologically and economically important parasite of wild and farmed salmon. In Scotland, Norway, and Eastern Canada, L. salmonis have developed resistance to emamectin benzoate (EMB), one of the few parasiticides available for salmon lice. Drug resistance mechanisms can be co...
journal_title:Evolutionary applications
pub_type: 杂志文章
doi:10.1111/eva.12237
更新日期:2015-02-01 00:00:00
abstract::Human-induced trait change has been documented in freshwater, marine, and terrestrial ecosystems worldwide. These trait changes are driven by phenotypic plasticity and contemporary evolution. While efforts to manage human-induced trait change are beginning to receive some attention, managing its ecological consequence...
journal_title:Evolutionary applications
pub_type: 杂志文章
doi:10.1111/j.1752-4571.2011.00212.x
更新日期:2012-02-01 00:00:00
abstract::Organisms are expected to respond to alterations in their survival by evolutionary changes in their life history traits. As agriculture and aquaculture have become increasingly intensive in the past decades, there has been growing interest in their evolutionary effects on the life histories of agri- and aquacultural p...
journal_title:Evolutionary applications
pub_type: 杂志文章
doi:10.1111/eva.12488
更新日期:2017-06-21 00:00:00
abstract::[This corrects the article DOI: 10.1111/eva.12607.]. ...
journal_title:Evolutionary applications
pub_type: 已发布勘误
doi:10.1111/eva.12800
更新日期:2019-11-01 00:00:00
abstract::The decreasing cost and increasing scope and power of emerging genomic technologies are reshaping the field of molecular ecology. However, many modern genomic approaches (e.g., RAD-seq) require large amounts of high-quality template DNA. This poses a problem for an active branch of conservation biology: genetic monito...
journal_title:Evolutionary applications
pub_type: 杂志文章
doi:10.1111/eva.12600
更新日期:2018-03-24 00:00:00
abstract::Temperature effects on the fatty acid (FA) profiles of phytoplankton, major primary producers in the ocean, have been widely studied due to their importance as industrial feedstocks and to their indispensable role as global producers of long-chain, polyunsaturated FA (PUFA), including omega-3 (ω3) FA required by organ...
journal_title:Evolutionary applications
pub_type: 杂志文章
doi:10.1111/eva.12798
更新日期:2019-04-23 00:00:00
abstract::Spatial and temporal trends and variation in life-history traits, including age and length at maturation, can be influenced by environmental and anthropogenic processes, including size-selective exploitation. Spawning adults in many wild Alaskan sockeye salmon populations have become shorter at a given age over the pa...
journal_title:Evolutionary applications
pub_type: 杂志文章
doi:10.1111/eva.12123
更新日期:2014-02-01 00:00:00
abstract::Fast increase of fish aquaculture production to meet consumer demands is accompanied by important ecological concerns such as disease outbreaks. Meanwhile, food waste is an important concern with fish products since they are highly perishable. Recent aquaculture and fish product microbiology, and more recently, microb...
journal_title:Evolutionary applications
pub_type: 杂志文章
doi:10.1111/eva.13027
更新日期:2020-06-09 00:00:00
abstract::Natural ecosystems are under pressure from increasing abiotic and biotic stressors, including climate change and novel pathogens, which are putting species at risk of local extinction, and altering community structure, composition and function. Here, we aim to assess adaptive variation in growth and fungal disease res...
journal_title:Evolutionary applications
pub_type: 杂志文章
doi:10.1111/eva.12796
更新日期:2019-04-15 00:00:00
abstract::Understanding the transition of bacterial species from commensal to pathogen, or vice versa, is a key application of evolutionary theory to preventative medicine. This requires working knowledge of the molecular interaction between hosts and bacteria, ecological interactions among microbes, spatial variation in bacter...
journal_title:Evolutionary applications
pub_type: 杂志文章,评审
doi:10.1111/eva.12231
更新日期:2015-01-01 00:00:00
abstract::Predictions about the consequences of a small population size on genetic and deleterious variation are fundamental to population genetics. As small populations are more affected by genetic drift, purifying selection acting against deleterious alleles is predicted to be less efficient, therefore increasing the risk of ...
journal_title:Evolutionary applications
pub_type: 杂志文章
doi:10.1111/eva.12872
更新日期:2019-09-30 00:00:00
abstract::Evolution has contributed to the successful invasion of exotic plant species in their introduced ranges, but how evolution affects particular control strategies is still under evaluation. For instance, classical biological control, a common strategy involving the utilization of highly specific natural enemies to contr...
journal_title:Evolutionary applications
pub_type: 杂志文章
doi:10.1111/eva.12134
更新日期:2014-03-01 00:00:00
abstract::Preservation of adaptive variation is a top priority of many species restoration programs, but most restoration activities are conducted without direct knowledge of selection that might foster or impair adaptation and restoration goals. In this study, we quantified geographic variation in selection on fry size of enda...
journal_title:Evolutionary applications
pub_type: 杂志文章
doi:10.1111/j.1752-4571.2010.00126.x
更新日期:2010-07-01 00:00:00
abstract::We review the results of a series of experiments involving Aedes aegypti and its microsporidian parasite Vavraia culicis to illustrate how intra-specific competition and parasitism shape life history traits. More specifically these experiments showed that some major components of virulence are host condition-dependent...
journal_title:Evolutionary applications
pub_type: 杂志文章
doi:10.1111/j.1752-4571.2007.00004.x
更新日期:2008-02-01 00:00:00
abstract::Delineating species is a difficult and seemingly uninteresting issue that is still essential to address. Taxonomic methodology is heterogeneous according to the taxa and scientists involved due to the disparate data quality and quantity and disagreements over the species concept. This has negative impacts on basic and...
journal_title:Evolutionary applications
pub_type: 杂志文章,评审
doi:10.1111/eva.12748
更新日期:2019-03-25 00:00:00
abstract::Cattle have been invaluable for the transition of human society from nomadic hunter-gatherers to sedentary farming communities throughout much of Europe, Asia and Africa since the earliest domestication of cattle more than 10,000 years ago. Although current understanding of relationships among ancestral populations re...
journal_title:Evolutionary applications
pub_type: 杂志文章
doi:10.1111/eva.12674
更新日期:2018-07-23 00:00:00
abstract::Currently, the effects of chronic, continuous low dose environmental irradiation on the mitochondrial genome of resident small mammals are unknown. Using the bank vole (Myodes glareolus) as a model system, we tested the hypothesis that approximately 50 generations of exposure to the Chernobyl environment has significa...
journal_title:Evolutionary applications
pub_type: 杂志文章
doi:10.1111/eva.12475
更新日期:2017-06-22 00:00:00
abstract::Assessing the potential of marine organisms to adapt genetically to increasing oceanic CO2 levels requires proxies such as heritability of fitness-related traits under ocean acidification (OA). We applied a quantitative genetic method to derive the first heritability estimate of survival under elevated CO2 conditions ...
journal_title:Evolutionary applications
pub_type: 杂志文章
doi:10.1111/eva.12248
更新日期:2015-04-01 00:00:00
abstract::Population dynamics of marine species that are sessile as adults are driven by oceanographic dispersal of larvae from spawning to nursery grounds. This is mediated by life-history traits such as the timing and frequency of spawning, larval behaviour and duration, and settlement success. Here, we use 1725 single nucleo...
journal_title:Evolutionary applications
pub_type: 杂志文章
doi:10.1111/eva.12932
更新日期:2020-02-24 00:00:00
abstract::The distribution of Asian ancestry in the genome of Danish Duroc pigs was investigated using whole-genome sequencing data from European wild boars, Danish Duroc, Chinese Meishan and Bamaxiang pigs. Asian haplotypes deriving from Meishan and Bamaxiang occur widely across the genome. Signatures of selection on Asian hap...
journal_title:Evolutionary applications
pub_type: 杂志文章
doi:10.1111/eva.12716
更新日期:2018-12-13 00:00:00
abstract::The evolutionary perspective of cancer (which origins and dynamics result from evolutionary processes) has gained significant international recognition over the past decade and generated a wave of enthusiasm among researchers. In this context, several authors proposed that insights into evolutionary and adaptation dyn...
journal_title:Evolutionary applications
pub_type: 杂志文章
doi:10.1111/eva.12265
更新日期:2015-07-01 00:00:00