Abstract:
:Brominated flame retardants (BFRs) are a large group of different substances used in numerous products to prevent fire hazards. Some of them are persistent in the environment, accumulate in the food chain and are of toxicological concern, while for others current data are limited. Meanwhile, BFRs have been found in many environmental media, foods, and biota including humans. This review presents recent findings obtained from monitoring data in environmental media relevant for human exposure, as well as dietary exposure. In this context, concentrations in indoor and ambient air and in house dust are outlined. Furthermore, we summarize human biomonitoring data on BFR levels in blood and breast milk. Current estimates of the overall exposure of the general population using different relevant subsets are also addressed. All of these data are discussed in relation to currently available toxicological reference values used for risk assessment purposes. Obviously, the exposure of the general population varies considerably in different parts of the world and even within countries. Polybrominated diphenyl ethers (PBDEs) and hexabromocyclododecane (HBCD) show the highest intake during infancy. While the highest intake for BDE 47 for all groups was observed in the US, the total BDE 209 and HBCD intake was highest in the UK. For HBCD and all PBDEs except BDE 209, diet accounts for a large proportion of the total intake during infancy in all countries. With regard to toddlers and adults, the contribution of diet to total intake is high in Germany and the UK, while in the US, the high concentrations of PBDE in dust resulted in a notably smaller proportion of the intake being attributed to diet.
journal_name
Int J Hyg Environ Healthauthors
Fromme H,Becher G,Hilger B,Völkel Wdoi
10.1016/j.ijheh.2015.08.004subject
Has Abstractpub_date
2016-01-01 00:00:00pages
1-23issue
1eissn
1438-4639issn
1618-131Xpii
S1438-4639(15)00105-4journal_volume
219pub_type
杂志文章,评审abstract::Prenatal exposure to polybrominated diphenyl ethers (PBDEs) have been reported to impair executive function in children, but little is known whether childhood PBDE exposures play a role. Using the Health Outcomes and Measures of the Environment (HOME) Study, a prospective birth cohort in the greater Cincinnati area, w...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2017.10.006
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Cadmium (Cd) and lead (Pb) are widespread environmental contaminants that are known nephrotoxins. However, their nephrotoxic effects at low-environmental exposure levels are debated. OBJECTIVE:We examined the association of blood Pb (B-Pb), blood Cd (B-Cd), urinary Pb (U-Pb) and urinary Cd (U-Cd) with estim...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2016.01.005
更新日期:2016-05-01 00:00:00
abstract:OBJECTIVE:This study investigated the metal distribution in blood samples from the general population and the risk of having high metal concentration for metal workers. METHODS:Metal concentrations were determined in archived blood samples from 1411 men and 1410 women (median age 59 and 57 years, respectively) collect...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2017.05.009
更新日期:2017-08-01 00:00:00
abstract::This paper presents a progress report of the French human biomonitoring (HBM) program established in 2010. This program has been designed to provide a national representative estimation of the French population's exposure to various environmental chemicals and to study the determinants of exposure. This program curren...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2016.11.005
更新日期:2017-03-01 00:00:00
abstract::A national survey was conducted to determine polychlorinated dibenzo-p-dioxins and dibenofurans (PCDD/Fs) and dioxin-like polychlorinated biphenyls (dl-PCBs) in human milk samples collected from 16 provinces in China to assess current exposure and temporal trends in China. The arithmetic mean concentration of total TE...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2016.07.013
更新日期:2016-11-01 00:00:00
abstract::Between January and October 1994, a study of the prevalence, intensity and clinical manifestations of onchocerciasis in nine communities of Toro local government area of Bauchi State, Nigeria was undertaken using the skin-snip method. Of the 1117 inhabitants examined, 188 (16.8%) were positive for microfilariae of Onc...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1078/1438-4639-00052
更新日期:2001-07-01 00:00:00
abstract::This paper reviews the existing literature on human exposure to polybrominated diphenyl ethers (PBDEs), with particular focus on external exposure routes (e.g. dust, diet, and air) and the resulting internal exposure to PBDEs (e.g. breast milk and blood). Being lipophilic and persistent organic compounds, PBDEs accumu...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章,评审
doi:10.1016/j.ijheh.2008.04.005
更新日期:2009-03-01 00:00:00
abstract::Human biomonitoring (HBM) has proven an extremely valuable tool for determining which chemicals are getting into people, detecting trends in population exposures over time, and identifying populations with exposures above background. The potential significance of the HBM data in the context of existing toxicology data...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2011.09.011
更新日期:2012-02-01 00:00:00
abstract::There are no publications on the frequency of environmental agents causing diseases in children presented at centers of environmental medicine. The aim of this study was to perform a statistical analysis of the data of children who visited the outpatient Unit of Environmental Medicine (UEM) at the University Hospital ...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1078/1438-4639-00162
更新日期:2002-07-01 00:00:00
abstract:BACKGROUND:The association between exposure to air pollutants and mental disorders among adults has been suggested, although results are not consistent. OBJECTIVE:To analyze the association between long-term exposure to air pollution and history of anxiety and depression disorders and of medication use (benzodiazepine...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2017.06.009
更新日期:2017-08-01 00:00:00
abstract::Contribution of diet and selected risk factors to the levels of four polyfluorinated compounds was evaluated. Data from National Health and Nutrition Examination Survey for the years 2003-2008 were used. Dietary factors accounted for 10.4% to 21.2% of the explained variation. Amount of milk consumed was found to be po...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2013.03.008
更新日期:2014-01-01 00:00:00
abstract::Parabens are widely used as antimicrobial preservatives in personal care and consumer products, food and pharmaceuticals. Due to their ubiquity, humans are constantly exposed to these chemicals. We assessed exposure to nine parabens (methyl-, ethyl-, n- and iso-propyl-, n- and iso-butyl-, benzyl-, pentyl- and heptyl p...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2015.07.005
更新日期:2015-10-01 00:00:00
abstract::Prolific growth of pathogenic Legionella pneumophila within engineered water systems and premise plumbing, and human exposure to aerosols containing this bacterium results in the leading health burden of any water-related pathogen in developed regions. Ecologically, free-living amoebae (FLA) are an important group of ...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2019.04.007
更新日期:2019-05-01 00:00:00
abstract::Adrenergic and cholinergic transmitters of the autonomic nervous system have important roles in the mutual interrelationships between the brain and the immune system. Besides expressing functional adrenergic and cholinergic receptors, lymphocytes and other immune cells were found to synthesize and release catecholamin...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章,评审
doi:10.1078/1438-4639-00076
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abstract::As a result of an international mandate adopted in 1992 at the United Nations Conference on the Environment and Development (UNCED), a globally harmonized system (GHS) for hazard communication has been developed. The work has involved significant contributions from numerous countries and international organizations. T...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1078/1438-4639-00241
更新日期:2003-08-01 00:00:00
abstract::Imidacloprid is a neonicotinoid insecticide commonly injected through agricultural drip irrigation systems to reduce the population of vine mealybugs (P. ficus) in grape farms. There is a growing concern of potential human health effects of imidacloprid, however, there is limited information on the exposure to imidacl...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2020.113625
更新日期:2020-09-17 00:00:00
abstract::Populations are exposed to mixtures of pesticides through their diet on a daily basis. The question of which substances should be assessed together remains a major challenge due to the complexity of the mixtures. In addition, the associated risk is difficult to characterise. The EuroMix project (European Test and Risk...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2018.12.002
更新日期:2019-03-01 00:00:00
abstract::In this study, we estimated the possibility of using benchmark dose (BMD) to assess the dose-response relationship between vinyl chloride monomer (VCM) exposure and chromosome damage. A group of 317 workers occupationally exposed to vinyl chloride monomer and 166 normal, unexposed control in Shandong Province northern...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2012.02.008
更新日期:2013-01-01 00:00:00
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journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章,评审
doi:10.1016/j.ijheh.2016.04.008
更新日期:2016-07-01 00:00:00
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journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2009.03.003
更新日期:2009-09-01 00:00:00
abstract::In Cologne, Germany, increased concentrations of perfluorinated compounds (PFC) have been observed in two private wells used for drinking water purposes. Both wells are located in the vicinity of a fire training area. Use of well water as a source of drinking water was prohibited by the Public Health Department of the...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2011.08.016
更新日期:2012-02-01 00:00:00
abstract::Food irradiation is being promoted as a simple process that can be used to effectively and significantly reduce food-borne illnesses around the world. However, a thorough review of the literature reveals a paucity of adequate research conducted to specifically address health concerns that may directly result from the ...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章,评审
doi:10.1078/1438-4639-00321
更新日期:2004-12-01 00:00:00
abstract::In this study, we evaluated the association between prenatal and postnatal exposure to environmental tobacco smoke and the development of insulin resistance in 10 year old children. Fasting blood samples were collected from 470 children participating in two prospective birth cohorts. Of those 276 were selected populat...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2011.04.004
更新日期:2011-09-01 00:00:00
abstract::Nowadays, coal workers' pneumoconiosis (CWP) is still believed to be the main occupational disease in China. However, information on the exact prevalence of the disease is not available. Therefore, the aims of our investigation were to provide the missing information in China by conducting a systematic evaluation of p...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章,meta分析
doi:10.1016/j.ijheh.2013.03.006
更新日期:2014-01-01 00:00:00
abstract::Perfluorinated compounds are fully fluorinated anthropogenic substances that have been used in various products, applications, and industrial processes. Due to their persistence and toxic effects, some of them are restricted, and therefore replacement products have been developed. The aim of the study was to quantify ...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2016.12.014
更新日期:2017-04-01 00:00:00
abstract:OBJECTIVE:Low beryllium exposure can induce pulmonary granulomatosis, so called berylliosis. For occupational health monitoring, it is more relevant to assess the internal dose of Be received by the lungs than urinary or atmospheric Be. Exhaled breath condensate (EBC) is a matrix collected non-invasively that derives f...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2015.08.003
更新日期:2016-01-01 00:00:00
abstract::Previous investigations of biofilms, generated in a silicone tube model have shown that the number of colony forming units (CFU) can reach 10(7)/cm(2), the total cell count (TCC) of microorganisms can be up to 10(8)cells/cm(2). The present study focuses on the situation in in-building distribution systems. Different c...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2010.04.006
更新日期:2010-06-01 00:00:00
abstract::Reference values (RV95) are statistically derived values comprising the rounded 95th percentiles within the 95% confidence interval and indicate the upper margin of background exposure to chemical substances in a population at a given time period. Based on representative national human biomonitoring data on several ur...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2018.06.001
更新日期:2018-07-01 00:00:00
abstract::7-Hydroxy-3,7-dimethyl-1-octanal, also known as 7-hydroxycitronellal (7-HC, CAS No. 107-75-5) is a synthetic fragrance widely used in cosmetic and hygiene products. Due to its large scope, 7-HC was selected for the development of a biomonitoring method suitable for the general population within the frame of the cooper...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2017.10.015
更新日期:2018-03-01 00:00:00
abstract::Ensuring safe drinking-water is the target of the Water Safety Plan (WSP) approach, which has been successfully applied to a large number of water supply systems around the world. Effective country-wide scaling up of WSP implementation requires an enabling environment at the policy level. By utilizing a multi-step mix...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2020.113553
更新日期:2020-07-01 00:00:00