Abstract：
:Epidemiologic evidence indicates that respiratory disease in infancy and childhood has respiratory health consequences in later life. Pulmonary function is considered a good index of early effects. This study assessed the relationship of pulmonary function in preschool children in Leipzig, Germany, and exposure to high levels of air pollution during early childhood. Spirometric measures were taken of 235 preschoolers (126 boys, 109 girls, mean age 5.1 +/- 1.3 years) attending 16 randomly selected daycare centres, using the 'Bosch Spiro 501' spirometer. The results showed decrements in the average FVC (85.5% predicted [pred]) and FEV1 (90.2% pred) differing with spatial variations in the ambient air pollution burden of the children's residential area. Exposure to a pollution profile of heavy traffic and/or domestic heating showed markedly lower FVC (78.9% and 85.5% pred, respectively) and FEV1 (82.4% and 88.5% pred). Miller's Diagnostic Quadrant Model of Disease Classification, categorizing pulmonary function data for preliminary diagnostic purposes, assessed the lung function values (FVC% pred/relative FEV1 [FEV1/FVC]%) of a significant number of children as 'restrictions' (n = 52; 22.1%). Summarizing: variations in spirometric indices were observed across exposure groups with a significant number of children showing signs of a restrictive ventilatory function. These cross-sectional data, however, do not permit to conclude with any degree of certainty that this is indicative of an early sign of a functional deficit.
journal_name
Int J Hyg Environ Healthauthors
Fritz GJ,Herbarth Odoi
10.1078/S1438-4639(04)70034-6keywords:
subject
Has Abstractpub_date
2001-03-01 00:00:00pages
235-44issue
3eissn
1438-4639issn
1618-131Xpii
S1438-4639(04)70034-6journal_volume
203pub_type
杂志文章abstract：BACKGROUND:Few studies have explored the association between perfluoroalkyl substances (PFAS) and reproductive hormones in adolescents and young adults. OBJECTIVES:This study aimed to investigate the association of PFAS with reproductive hormones in adolescents and young adults. METHODS:We recruited 540 subjects aged...
journal_title：International journal of hygiene and environmental health
pub_type： 杂志文章
doi：10.1016/j.ijheh.2015.03.008
更新日期：2015-07-01 00:00:00
abstract：:Household water treatment using sodium hypochlorite (NaOCl) has been recognized as a cost-effective means of reducing the heavy burden of diarrhea and other waterborne diseases, especially among populations without access to improved water supplies. Sodium dichloroisocyanurate (NaDCC), which is widely used in emergenc...
journal_title：International journal of hygiene and environmental health
pub_type： 杂志文章,评审
doi：10.1016/j.ijheh.2005.11.004
更新日期：2006-03-01 00:00:00
abstract：:The first national human biomonitoring in Slovenia surveyed cadmium (Cd), lead (Pb), mercury (Hg), arsenic (As), manganese (Mn), selenium (Se), copper (Cu) and zinc (Zn) in a childbearing population (18-49 years) selected from lactating primiparous women and men (N = 1084). The overall aim was to estimate trace elemen...
journal_title：International journal of hygiene and environmental health
pub_type： 杂志文章
doi：10.1016/j.ijheh.2019.02.008
更新日期：2019-04-01 00:00:00
abstract：OBJECTIVE:Low beryllium exposure can induce pulmonary granulomatosis, so called berylliosis. For occupational health monitoring, it is more relevant to assess the internal dose of Be received by the lungs than urinary or atmospheric Be. Exhaled breath condensate (EBC) is a matrix collected non-invasively that derives f...
journal_title：International journal of hygiene and environmental health
pub_type： 杂志文章
doi：10.1016/j.ijheh.2015.08.003
更新日期：2016-01-01 00:00:00
abstract：:Due to the decrease of lead intake via inhalation route, the oral route, particularly from drinking water in cities with lead installations, gains relative importance. In two surveys a total of 288 objects were investigated and 1768 samples were analysed. The first series with 51 objects using a field experimental app...
journal_title：International journal of hygiene and environmental health
pub_type： 杂志文章
doi：10.1078/1438-4639-00164
更新日期：2002-07-01 00:00:00
abstract：:The epidemiological evidence that ambient exposure, including particulate matter (PM) is related to adverse health outcomes continues to mount. Inflammation and disease of the upper respiratory tract are commonly suggested as effects of ambient exposure. Therefore we studied both ambient exposure and nasal effects in ...
journal_title：International journal of hygiene and environmental health
pub_type： 杂志文章
doi：10.1078/1438-4639-00122
更新日期：2002-04-01 00:00:00
abstract：BACKGROUND:The International Agency for Research on Cancer (IARC) has recently classified glyphosate as a Group 2A 'probably carcinogenic to humans'. Due to this carcinogenic classification and resulting international debate, there is an increased demand for studies evaluating human health effects from glyphosate expos...
journal_title：International journal of hygiene and environmental health
pub_type： 杂志文章
doi：10.1016/j.ijheh.2018.09.004
更新日期：2019-03-01 00:00:00
abstract：BACKGROUND AND AIM:Moderate fish consumption is recommended for prevention of coronary heart disease (CHD) as docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) have known beneficial effects on risk factors such as reducing blood pressure (BP) and increasing paraoxonase-1 (PON-1) activity. However concomitant m...
journal_title：International journal of hygiene and environmental health
pub_type： 杂志文章
doi：10.1016/j.ijheh.2016.11.004
更新日期：2017-04-01 00:00:00
abstract：:Multiple chemical sensitivity (MCS) is characterised by adverse effects due to exposure to low levels of chemical substances. The aetiology is unknown, but chemical related respiratory symptoms have been found associated with positive patch test. The purpose of this study was to investigate the relationship between cu...
journal_title：International journal of hygiene and environmental health
pub_type： 杂志文章
doi：10.1016/j.ijheh.2011.01.003
更新日期：2011-06-01 00:00:00
abstract：:Bacteria of the genus of Bdellovibrio are highly motile Gram-negative predators of other Gram-negative bacteria causing lysis of their prey. Here we report results of studies on the interactions of Bdellovibrio with species of Alcaligenes, Campylobacter, Erwinia, Escherichia, Helicobacter, Pseudomonas, Legionella, and...
journal_title：International journal of hygiene and environmental health
pub_type： 杂志文章
doi：10.1016/j.ijheh.2010.08.004
更新日期：2010-11-01 00:00:00
abstract：BACKGROUND:Even though increased environmental platinum levels were found since the introduction of automobile catalytic converters, little is known about the pathways of corporal uptake and the bioavailability of platinum in the general adult population. The aim of this study is to identify and quantify the main expos...
journal_title：International journal of hygiene and environmental health
pub_type： 杂志文章
doi：10.1016/j.ijheh.2005.07.004
更新日期：2005-01-01 00:00:00
abstract：:Cervical cancer (CC) is potentially the most preventable and treatable cancer in human but it is a leading cause for cancer morbidity and mortality in women around the world. Therefore, more innovative prevention and treatment protocols need to be developed and implemented. With better understanding of the etiology of...
journal_title：International journal of hygiene and environmental health
pub_type： 杂志文章,评审
doi：10.1016/j.ijheh.2006.10.003
更新日期：2007-12-01 00:00:00
abstract：BACKGROUND:Conflicting evidence concerning possible harm from mercury (Hg) in regard to offspring cognition if the woman eats fish has prompted this study to examine evidence from a British pre-birth cohort to investigate the relationship between the two. METHODS:Pregnant women (median prenatal blood mercury 1.86μg/L)...
journal_title：International journal of hygiene and environmental health
pub_type： 杂志文章
doi：10.1016/j.ijheh.2017.07.004
更新日期：2017-10-01 00:00:00
abstract：:Contribution of diet and selected risk factors to the levels of four polyfluorinated compounds was evaluated. Data from National Health and Nutrition Examination Survey for the years 2003-2008 were used. Dietary factors accounted for 10.4% to 21.2% of the explained variation. Amount of milk consumed was found to be po...
journal_title：International journal of hygiene and environmental health
pub_type： 杂志文章
doi：10.1016/j.ijheh.2013.03.008
更新日期：2014-01-01 00:00:00
abstract：:Brominated flame retardants (BFRs) are a large group of different substances used in numerous products to prevent fire hazards. Some of them are persistent in the environment, accumulate in the food chain and are of toxicological concern, while for others current data are limited. Meanwhile, BFRs have been found in ma...
journal_title：International journal of hygiene and environmental health
pub_type： 杂志文章,评审
doi：10.1016/j.ijheh.2015.08.004
更新日期：2016-01-01 00:00:00
abstract：:Airborne bioaerosols and Microbial Volatile Organic Compounds (MVOC) concentrations were simultaneously monitored at a composting facility and the main determinants of atmospheric concentrations were characterised, in order to help protect workers from potential adverse health effects. Microorganisms and MVOC were sam...
journal_title：International journal of hygiene and environmental health
pub_type： 杂志文章
doi：10.1016/j.ijheh.2010.06.001
更新日期：2010-09-01 00:00:00
abstract：:Human campylobacteriosis is currently the most common cause of acute bacterial gastroenteritis on the island of Ireland, accounting for over 3,000 laboratory reports per year, where circa 2,000 reports originate from the Republic of Ireland and circa 1,000 reports from Northern Ireland. Elsewhere, consumption of conta...
journal_title：International journal of hygiene and environmental health
pub_type： 杂志文章
doi：10.1078/1438-4639-00215
更新日期：2003-06-01 00:00:00
abstract：OBJECTIVE:Unprotected sun exposure especially during childhood is a risk factor for skin cancer. A combined use of sun protection measures is recommended to protect children. However, the prevalence and determinants for combined use have been scarcely studied in children. The objective of this study was to identify det...
journal_title：International journal of hygiene and environmental health
pub_type： 杂志文章
doi：10.1016/j.ijheh.2013.07.013
更新日期：2014-03-01 00:00:00
abstract：:Previous investigations of biofilms, generated in a silicone tube model have shown that the number of colony forming units (CFU) can reach 10(7)/cm(2), the total cell count (TCC) of microorganisms can be up to 10(8)cells/cm(2). The present study focuses on the situation in in-building distribution systems. Different c...
journal_title：International journal of hygiene and environmental health
pub_type： 杂志文章
doi：10.1016/j.ijheh.2010.04.006
更新日期：2010-06-01 00:00:00
abstract：:Ensuring safe drinking-water is the target of the Water Safety Plan (WSP) approach, which has been successfully applied to a large number of water supply systems around the world. Effective country-wide scaling up of WSP implementation requires an enabling environment at the policy level. By utilizing a multi-step mix...
journal_title：International journal of hygiene and environmental health
pub_type： 杂志文章
doi：10.1016/j.ijheh.2020.113553
更新日期：2020-07-01 00:00:00
abstract：:We conducted cost effectiveness analyses of four different CLTS interventions implemented in Ethiopia and Ghana. In each country, a pilot approach in which additional local actors were trained in CLTS facilitation was compared to the conventional approach. Data were collected using bottom-up costing, household surveys...
journal_title：International journal of hygiene and environmental health
pub_type： 杂志文章
doi：10.1016/j.ijheh.2020.113682
更新日期：2020-12-24 00:00:00
abstract：BACKGROUND:The Korean government implemented partial smoke-free regulations in hospitality venues ≥150 m2 in July 2013 and in venues ≥100 m2 in February 2014. This study examined changes in urinary cotinine concentrations in the Korean non-smoking adult population, and socio-demographic subgroups thereof, between 2012 ...
journal_title：International journal of hygiene and environmental health
pub_type： 杂志文章
doi：10.1016/j.ijheh.2019.113419
更新日期：2020-03-01 00:00:00
abstract：:Ultimately, the health and quality of life of all human beings depend upon the environment and ecosystems to which we are directly and indirectly connected. The papers in this special edition address a number of the critical environmental health issues on which U.S. government agencies and their collaborating partners...
journal_title：International journal of hygiene and environmental health
pub_type： 杂志文章
doi：10.1078/1438-4639-00221
更新日期：2003-08-01 00:00:00
abstract：:Since chlorhexidine is effective against microorganisms, it is widely recommended in dentistry. However, studies have provided evidence that chlorhexidine is toxic for a variety of cell types. In order to identify potential genotoxins in different cell types, the purpose of this study was to investigate whether chlorh...
journal_title：International journal of hygiene and environmental health
pub_type： 杂志文章
doi：10.1016/j.ijheh.2006.09.001
更新日期：2007-03-01 00:00:00
abstract：:Non-carcinogenic effects in low-level (< 100 μgL(-1)) arsenic (As)-impacted populations, such as the development and progression of type-2 diabetes mellitus (T2DM), are often neglected given the primary emphasis of public health authorities on As carcinogenicity. We gathered studies reporting urinary biomarkers of As ...
journal_title：International journal of hygiene and environmental health
pub_type： 杂志文章,meta分析
doi：10.1016/j.ijheh.2012.07.001
更新日期：2013-01-01 00:00:00
abstract：:Food irradiation is being promoted as a simple process that can be used to effectively and significantly reduce food-borne illnesses around the world. However, a thorough review of the literature reveals a paucity of adequate research conducted to specifically address health concerns that may directly result from the ...
journal_title：International journal of hygiene and environmental health
pub_type： 杂志文章,评审
doi：10.1078/1438-4639-00321
更新日期：2004-12-01 00:00:00
abstract：BACKGROUND:Cadmium (Cd) and lead (Pb) are widespread environmental contaminants that are known nephrotoxins. However, their nephrotoxic effects at low-environmental exposure levels are debated. OBJECTIVE:We examined the association of blood Pb (B-Pb), blood Cd (B-Cd), urinary Pb (U-Pb) and urinary Cd (U-Cd) with estim...
journal_title：International journal of hygiene and environmental health
pub_type： 杂志文章
doi：10.1016/j.ijheh.2016.01.005
更新日期：2016-05-01 00:00:00
abstract：BACKGROUND:The observed deficit of lung cancer in farmers has been partly attributed to exposure to organic dusts and endotoxins based largely on surrogate metrics. To move beyond these surrogates for etiological studies, we characterized task-based and time-weighted average (TWA) exposure to inhalable endotoxin, (1 → ...
journal_title：International journal of hygiene and environmental health
pub_type： 杂志文章
doi：10.1016/j.ijheh.2020.113525
更新日期：2020-07-01 00:00:00
abstract：:7-Hydroxy-3,7-dimethyl-1-octanal, also known as 7-hydroxycitronellal (7-HC, CAS No. 107-75-5) is a synthetic fragrance widely used in cosmetic and hygiene products. Due to its large scope, 7-HC was selected for the development of a biomonitoring method suitable for the general population within the frame of the cooper...
journal_title：International journal of hygiene and environmental health
pub_type： 杂志文章
doi：10.1016/j.ijheh.2017.10.015
更新日期：2018-03-01 00:00:00
abstract：:The dissolution of metal-containing particles in the gastric compartment is poorly understood. The purpose of this study was to elucidate the influence of artificial gastric juice chemical composition on bioaccessibility of metals associated with ingestion-based health concerns. Dissolution rates were evaluated for we...
journal_title：International journal of hygiene and environmental health
pub_type： 杂志文章
doi：10.1016/j.ijheh.2009.12.006
更新日期：2010-03-01 00:00:00
