Research participants' perceptions and views on consent for biobank research: a review of empirical data and ethical analysis.

abstract：BACKGROUND:A requisite for ethical human subjects research is that participation should be informed and voluntary. Participation during the informed consent process by way of asking questions is an indicator of the extent to which consent is informed. AIMS:The aims of this study were to assess the extent to which pare...

journal_title：BMC medical ethics

authors： Rajaraman D,Jesuraj N,Geiter L,Bennett S,Grewal HM,Vaz M,TB Trials Study Group.

更新日期：2011-02-15 00:00:00

abstract：BACKGROUND:Patient outcome after serious brain injury is highly variable. Following a period of coma, some patients recover while others progress into a vegetative state (unresponsive wakefulness syndrome) or minimally conscious state. In both cases, assessment is difficult and misdiagnosis may be as high as 43%. Recen...

journal_title：BMC medical ethics

authors： Weijer C,Peterson A,Webster F,Graham M,Cruse D,Fernández-Espejo D,Gofton T,Gonzalez-Lara LE,Lazosky A,Naci L,Norton L,Speechley K,Young B,Owen AM

更新日期：2014-05-20 00:00:00

abstract：BACKGROUND:Although informed consent is an integral part of clinical practice, its current doctrine remains mostly a matter of law and mainstream ethics rather than empirical research. There are scarce empirical data on patients' perceived purpose of informed consent, which may include administrative routine/courtesy g...

journal_title：BMC medical ethics

authors： Hammami MM,Al-Gaai EA,Al-Jawarneh Y,Amer H,Hammami MB,Eissa A,Qadire MA

更新日期：2014-01-10 00:00:00

abstract：BACKGROUND:Community consultation is increasingly recommended, and in some cases, required by ethical review boards for research that involves higher levels of ethical risk such as international research and research with vulnerable populations. In designing a randomised control trial of a mental health intervention us...

journal_title：BMC medical ethics

authors： Shanks L,Moroni C,Rivera IC,Price D,Clementine SB,Pintaldi G

更新日期：2015-06-02 00:00:00

abstract：BACKGROUND:The generation of evidence is integral to the work of public health and health service providers. Traditionally, ethics has been addressed differently in research projects, compared with other forms of evidence generation, such as quality improvement, program evaluation, and surveillance, with review of non-...

journal_title：BMC medical ethics

authors： Willison DJ,Ondrusek N,Dawson A,Emerson C,Ferris LE,Saginur R,Sampson H,Upshur R

更新日期：2014-08-08 00:00:00

abstract：BACKGROUND:Making particular use of Shale's analysis, this paper discusses the notion of leadership in the context of palliative medicine. Whilst offering a critical perspective, I build on the philosophy of palliative care offered by Randall and Downie and suggest that the normative structure of this medical specialit...

journal_title：BMC medical ethics

authors： Emmerich N

更新日期：2018-06-05 00:00:00

abstract：BACKGROUND:Mobile applications and socio-sexual networking websites are used by outreach workers to respond synchronously to questions and provide information, resources, and referrals on sexual health and STI/HIV prevention, testing, and care to gay, bisexual and other men who have sex with men (GB2M). This explorator...

journal_title：BMC medical ethics

authors： Fantus S,Souleymanov R,Lachowsky NJ,Brennan DJ

更新日期：2017-11-03 00:00:00

abstract：BACKGROUND:Few empirical studies have been found that explore ethical challenges among persons in high public positions that are responsible for elder care. The aim of this paper was to illuminate the meaning of being in ethically difficult situations related to elder care as experienced by high level decision-makers. ...

journal_title：BMC medical ethics

authors： Mamhidir AG,Kihlgren M,Sorlie V

更新日期：2007-04-10 00:00:00

abstract：BACKGROUND:Few studies have examined factors associated with willingness of people living with HIV (PLHIV) to participate in HIV treatment clinical trials in Sub-Saharan Africa. We assessed the factors associated with participation of PLHIV in HIV treatment clinical trials research at a large urban clinical and researc...

journal_title：BMC medical ethics

authors： Sebatta DE,Siu G,Nabeta HW,Anguzu G,Walimbwa S,Lamorde M,Bukenya B,Kambugu A

更新日期：2020-08-24 00:00:00

abstract：BACKGROUND:In most socialised health systems there are formal processes that manage resource scarcity and determine the allocation of funds to health services in accordance with their priority. In this analysis, part of a larger qualitative study examining the ethical issues entailed in doctors' participation as techni...

journal_title：BMC medical ethics

authors： Gallagher S,Little M,Hooker C

更新日期：2018-07-24 00:00:00

abstract：BACKGROUND:Partnering with patients in healthcare research now benefits from a strong rationale and is encouraged by funding agencies and research institutions. However, this new approach raises ethical issues for patients, researchers, research professionals and administrators. The main objective of this review is to ...

journal_title：BMC medical ethics

authors： Martineau JT,Minyaoui A,Boivin A

更新日期：2020-05-11 00:00:00

abstract：BACKGROUND:This paper explores ethical concerns arising in healthcare integration. We argue that integration is necessary imperative for meeting contemporary and future healthcare challenges, a far stronger evidence base for the conditions of its effectiveness is required. In particular, given the increasing emphasis a...

journal_title：BMC medical ethics

authors： McKeown A,Cliffe C,Arora A,Griffin A

更新日期：2019-07-03 00:00:00

abstract：BACKGROUND:Consenting for retrospective medical records-based research (MR) and leftover tissue-based research (TR) continues to be controversial. Our objective was to survey Saudis attending outpatient clinics at a tertiary care hospital on their personal preference and perceptions of norm and current practice in rela...

journal_title：BMC medical ethics

authors： Al-Qadire MM,Hammami MM,Abdulhameed HM,Al Gaai EA

更新日期：2010-10-18 00:00:00

abstract：BACKGROUND:Africa continues to bear a disproportionate share of the global HIV/AIDS, tuberculosis (TB) and malaria burden. The development and distribution of safe, effective and affordable vaccines is critical to reduce these epidemics. However, conducting HIV/AIDS, TB, and/or malaria vaccine trials simultaneously in ...

journal_title：BMC medical ethics

authors： Mamotte N,Wassenaar D,Koen J,Essack Z

更新日期：2010-03-09 00:00:00

abstract：BACKGROUND:Evidence concerning how Japanese physicians think and behave in specific clinical situations that involve withholding or withdrawal of medical interventions for end-of-life or frail elderly patients is yet insufficient. METHODS:To analyze decisions and actions concerning the withholding/withdrawal of life-s...

journal_title：BMC medical ethics

authors： Bito S,Asai A

更新日期：2007-06-19 00:00:00

abstract：BACKGROUND:Large-scale linkage of international clinical datasets could lead to unique insights into disease aetiology and facilitate treatment evaluation and drug development. Hereto, multi-stakeholder consortia are currently designing several disease-specific translational research platforms to enable international h...

journal_title：BMC medical ethics

authors： Kalkman S,Mostert M,Gerlinger C,van Delden JJM,van Thiel GJMW

更新日期：2019-03-28 00:00:00

abstract：BACKGROUND:Several charters of rights have been issued in Europe to solemnly proclaim the rights of children during their hospital stay. However, notwithstanding such general declarations, the actual implementation of hospitalized children's rights is unclear. The purpose of this study was to understand to which extent...

journal_title：BMC medical ethics

authors： Bisogni S,Aringhieri C,McGreevy K,Olivini N,Lopez JR,Ciofi D,Merlo AM,Mariotti P,Festini F

更新日期：2015-05-13 00:00:00

abstract：BACKGROUND:Professional guidelines have addressed ethical dilemmas posed by a few types of nontraditional procreative arrangements (e.g., gamete donations between family members), but many questions arise regarding how providers view and make decisions about these and other such arrangements. METHODS:Thirty-seven ART ...

journal_title：BMC medical ethics

authors： Klitzman R

更新日期：2017-02-28 00:00:00

abstract：BACKGROUND:South Africa currently has a pluralistic health care system with separate public and private sectors. It is, however, moving towards a socialised model with the introduction of National Health Insurance. The South African legislative environment has changed recently with the promulgation of the Consumer Prot...

journal_title：BMC medical ethics

authors： Rowe K,Moodley K

更新日期：2013-03-21 00:00:00

abstract：BACKGROUND:Expectations of receiving personal health information as a fringe benefit of biospecimen donation-termed diagnostic misconception-are increasingly documented. We developed an instrument measuring conflation of observational biospecimen-based research and clinical care for use with Latino communities, who may...

journal_title：BMC medical ethics

authors： Knerr S,Ceballos RM

更新日期：2015-07-17 00:00:00

abstract：BACKGROUND:Efforts to improve patients' understanding of their own medical treatments or research in which they are involved are progressing, especially with regard to informed consent procedures. We aimed to design a multisource informed consent procedure that is easily adaptable to both clinical and research applicat...

journal_title：BMC medical ethics

authors： Cervo S,Rovina J,Talamini R,Perin T,Canzonieri V,De Paoli P,Steffan A

更新日期：2013-07-30 00:00:00

abstract：BACKGROUND:Intensive care physicians often must rely on substitute decision makers to address all dimensions of the construct of "best interest" for incapable, critically ill patients. This task involves identifying prior wishes and to facilitate the substitute decision maker's understanding of the incapable patient's ...

journal_title：BMC medical ethics

authors： Ratnapalan M,Cooper AB,Scales DC,Pinto R

更新日期：2010-02-10 00:00:00

abstract：BACKGROUND:Since 2010, the European Journal of Anaesthesiology has required the reporting of five items concerning ethical approval in articles describing human research: ethics committee's name and address, chairperson's name, study's protocol number and approval date. We aimed to assess whether this requirement has h...

journal_title：BMC medical ethics

authors： Zoccatelli D,Tramèr MR,Elia N

更新日期：2018-06-08 00:00:00

abstract：BACKGROUND:The progress of electronic health technologies and biobanks holds enormous promise for efficient research. Evidence shows that studies based on sharing and secondary use of data/samples have the potential to significantly advance medical knowledge. However, sharing of such resources for international collabo...

journal_title：BMC medical ethics

authors： Bernasconi L,Şen S,Angerame L,Balyegisawa AP,Hong Yew Hui D,Hotter M,Hsu CY,Ito T,Jörger F,Krassnitzer W,Phillips AT,Li R,Stockley L,Tay F,von Heijne Widlund C,Wan M,Wong C,Yau H,Hiemstra TF,Uresin Y,Senti G

更新日期：2020-01-21 00:00:00

abstract：BACKGROUND:In August 2017, Chile lifted its complete ban on abortion by permitting abortion in three limited circumstances: 1) to save a woman's life, 2) lethal fetal anomaly, and 3) rape. The new law allows regulated use of conscientious objection (CO) in abortion care, including allowing institutions to register as o...

journal_title：BMC medical ethics

authors： Biggs MA,Casas L,Ramm A,Baba CF,Correa SP

更新日期：2020-05-24 00:00:00

abstract：BACKGROUND:We analyzed the patients' perception of prenatal diagnosis of fetal cardiac pathology, and the reasons for choosing to continue with pregnancy despite being eligible to receive a medical termination of pregnancy. We also identified the challenges, the motives interfering in decision-making, and the consequen...

journal_title：BMC medical ethics

authors： Abi Tayeh G,Jouannic JM,Mansour F,Kesrouani A,Attieh E

更新日期：2018-05-02 00:00:00

abstract：BACKGROUND:Biomarker research is gaining increasing attention focusing on the preclinical stages of the disease. Such interest requires special attention for communication and disclosure in clinical contexts. Many countries give dementia a high health policy priority by developing national strategies and by improving g...

journal_title：BMC medical ethics

authors： Alpinar-Sencan Z,Schicktanz S

更新日期：2020-05-11 00:00:00

abstract：BACKGROUND:Studies on informed consent to medical research conducted in low or middle-income settings have increased, including empirical investigations of consent to genetic research. We investigated voluntary participation and comprehension of informed consent among women involved in a genetic epidemiological study o...

journal_title：BMC medical ethics

authors： Marshall PA,Adebamowo CA,Adeyemo AA,Ogundiran TO,Strenski T,Zhou J,Rotimi CN

更新日期：2014-05-13 00:00:00

abstract：BACKGROUND:A child is a developing person with evolving capacities that include autonomy, mental (decisional) capacity and capacity to assume responsibility. Hence, children are entitled to participatory (autonomy) rights in South Africa as observed in the Children's Act 38 of 2005. According to section 129 of the Act ...

journal_title：BMC medical ethics

authors： Ganya W,Kling S,Moodley K

更新日期：2016-11-02 00:00:00

abstract：BACKGROUND:It is widely acknowledged that there is a global divide on health care and health research known as the 10/90 divide. METHODS:A retrospective survey of articles published in the BMJ, Lancet, NEJM, Annals of Internal Medicine & JAMA in a calendar year to examine the contribution of the developing world to me...

journal_title：BMC medical ethics

authors： Sumathipala A,Siribaddana S,Patel V

更新日期：2004-10-04 00:00:00