当前位置： SCI文献检索 > JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY期刊下所有文献 > Long-QT Syndrome and Therapy for Attention Deficit/Hyperactivity Disorder.

Long-QT Syndrome and Therapy for Attention Deficit/Hyperactivity Disorder.

Abstract：

INTRODUCTION:Stimulants are the mainstay therapy for attention deficit/hyperactivity disorder (ADHD) and are associated with adrenergic side effects. There are limited data on the clinical course of patients treated for ADHD who have long-QT syndrome (LQTS), for which β-blockade is the goal of therapy. METHODS:LQTS patients from the Rochester-based LQTS Registry (open-enrollment between 1979 and 2003; follow-up from 1979 to present) treated with stimulant or nonstimulant ADHD medications (n = 48) were compared to a 2:1 age-, gender-, and QTc-duration matched LQTS control group not exposed to ADHD medications (n = 96). Kaplan-Meier and Cox proportional hazards regression analyses were used to evaluate risk of cardiac events (syncope, aborted cardiac arrest, and sudden cardiac death) in LQTS patients treated with ADHD medications. RESULTS:During a mean follow-up of 7.9 ± 5.4 years after initiation of ADHD medication at a mean age 10.7 ±7.3 years, there was a 62% cumulative probability of cardiac events in the ADHD treatment group compared to 28% in the matched LQTS control group (P < 0.001). Time-dependent use of ADHD medication was associated with an increased risk for cardiac events (HR = 3.07; P = 0.03) in the multivariate Cox model adjusted for time-dependent β-blocker use and prior cardiac events. Subgroup gender analyses showed that time-dependent ADHD medication was associated with an increased risk in male LQTS patients (HR = 6.80, P = 0.04). CONCLUSIONS:LQTS patients treated with ADHD medications have increased risk for cardiac events, particularly syncope, and this risk is augmented in males. The findings highlight the importance of heightened surveillance for LQTS patients on ADHD medications.

journal_name

J Cardiovasc Electrophysiol

journal_title

Journal of cardiovascular electrophysiology

authors

Zhang C,Kutyifa V,Moss AJ,McNitt S,Zareba W,Kaufman ES

doi

10.1111/jce.12739

subject

Has Abstract

pub_date

2015-10-01 00:00:00

pages

1039-44

issue

10

eissn

1045-3873

issn

1540-8167

journal_volume

26

pub_type

杂志文章,随机对照试验

相关文献

JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY文献大全
  • Interatrial mechanical dyssynchrony worsened atrial mechanical function in sinus node disease with or without paroxysmal atrial fibrillation.

    abstract：INTRODUCTION:Atrial electromechanical dysfunction might contribute to the development of atrial fibrillation (AF) in patients with sinus node disease (SND). The aim of this study was to investigate the prevalence and impact of atrial mechanical dyssynchrony on atrial function in SND patients with or without paroxysmal ...

    journal_title：Journal of cardiovascular electrophysiology

    pub_type： 杂志文章

    doi：10.1111/j.1540-8167.2009.01547.x

    authors： Wang M,Lau CP,Zhang XH,Siu CW,Lee KL,Yan GH,Yue WS,Tse HF

    更新日期：2009-11-01 00:00:00

  • Is pursuit of termination of atrial fibrillation during catheter ablation of great value in patients with longstanding persistent atrial fibrillation?

    abstract：BACKGROUND:The reliable endpoint for ablation of longstanding persistent atrial fibrillation (LPAF) has not been clearly established. METHODS AND RESULTS:This study included 140 patients who underwent catheter ablation for drug-refractory LPAF. A stepwise ablation approach included circumferential pulmonary vein isola...

    journal_title：Journal of cardiovascular electrophysiology

    pub_type： 杂志文章

    doi：10.1111/j.1540-8167.2012.02370.x

    authors： Park YM,Choi JI,Lim HE,Park SW,Kim YH

    更新日期：2012-10-01 00:00:00

  • The different mechanisms between late and very late recurrences of atrial fibrillation in patients undergoing a repeated catheter ablation.

    abstract：INTRODUCTION:The mechanisms of late (<1 year after the ablation) and very late (>1 year after the ablation) recurrences of paroxysmal atrial fibrillation (AF) after catheter ablation have not been reported. METHODS AND RESULTS:Fifty consecutive patients undergoing a repeated electrophysiologic study to investigate the...

    journal_title：Journal of cardiovascular electrophysiology

    pub_type： 杂志文章

    doi：10.1111/j.1540-8167.2005.00323.x

    authors： Hsieh MH,Tai CT,Lee SH,Lin YK,Tsao HM,Chang SL,Lin YJ,Wongchaoen W,Lee KT,Chen SA

    更新日期：2006-03-01 00:00:00

  • Intracardiac thrombosis in patients with arrhythmogenic right ventricular cardiomyopathy.

    abstract：BACKGROUND:Intracardiac thrombus has been reported in anecdotal cases of arrhythmogenic right ventricular cardiomyopathy (ARVC). This prospective study aimed to determine the prevalence, risk factors, and prognosis of intracardiac thrombosis in patients with ARVC. METHODS:From February 2004 to August 2013, transthorac...

    journal_title：Journal of cardiovascular electrophysiology

    pub_type： 杂志文章

    doi：10.1111/jce.12501

    authors： Wu L,Yao Y,Chen G,Fan X,Zheng L,Ding L,Zhang S

    更新日期：2014-12-01 00:00:00

  • Echocardiographic Predictors of Long-Term Survival in Patients Undergoing Cardiac Resynchronization Therapy: What Is the Optimal Metric?

    abstract：BACKGROUND:Multiple definitions of reverse ventricular remodeling (RVR) employing various changes in left ventricular end-systolic (LVESV) or diastolic volumes (LVEDVs) or left ventricular ejection fraction (LVEF) have been used in determining cardiac resynchronization therapy (CRT) response, making comparability acros...

    journal_title：Journal of cardiovascular electrophysiology

    pub_type： 杂志文章

    doi：10.1111/jce.13175

    authors： Rickard J,Baranowski B,Wilson Tang WH,Grimm RA,Niebauer M,Cantillion D,Wilkoff BL,Varma N

    更新日期：2017-04-01 00:00:00

  • Relationship between complex fractionated atrial electrograms during atrial fibrillation and the critical site of atrial tachycardia that develops after catheter ablation for atrial fibrillation.

    abstract：INTRODUCTION:Complex fractionated atrial electrograms (CFAEs) are a substrate modification target in patients with atrial fibrillation (AF). However, whether CFAEs can be also arrhythmogenic grounds of atrial tachycardia (AT) presenting after AF ablation remains to be determined. We investigated the relationship betwee...

    journal_title：Journal of cardiovascular electrophysiology

    pub_type： 临床试验,杂志文章

    doi：10.1111/jce.12300

    authors： Ban JE,Chen YL,Park HC,Lee HS,Lee DI,Choi JI,Lim HE,Park SW,Kim YH

    更新日期：2014-02-01 00:00:00

  • Frequency-dependent electrophysiologic effects of d,l-sotalol and quinidine and modulation by beta-adrenergic stimulation.

    abstract：INTRODUCTION:Frequency-dependent electrophysiologic actions of oral quinidine and oral sotalol may be clinically important, but these properties and their modulation by beta-adrenergic sympathetic stimulation have not been determined. METHODS AND RESULTS:The frequency-dependent effects of oral quinidine (n = 17) and o...

    journal_title：Journal of cardiovascular electrophysiology

    pub_type： 杂志文章

    doi：10.1111/j.1540-8167.1996.tb00505.x

    authors： Sager PT,Behboodikhah M

    更新日期：1996-02-01 00:00:00

  • Is pulmonary vein isolation enough for persistent atrial fibrillation?

    abstract：:Pulmonary vein isolation (PVI) is a well-established treatment for atrial fibrillation (AF); however, studies report suboptimal outcomes in persistent AF. Adjuvant ablation targeting the substrate outside the pulmonary veins has been proposed to improve the success rates of the procedure. In this review, we summarize ...

    journal_title：Journal of cardiovascular electrophysiology

    pub_type： 杂志文章,评审

    doi：10.1111/jce.14381

    authors： Terricabras M,Verma A

    更新日期：2020-08-01 00:00:00

  • Traditional and nonlinear heart rate variability are each independently associated with mortality after myocardial infarction.

    abstract：INTRODUCTION:Decreased heart rate variability (HRV) and abnormal nonlinear HRV shortly after myocardial infarction (MI) are risk factors for mortality. Traditional HRV predicts mortality in patients with a range of times post-MI, but the association of nonlinear HRV and outcome in this population is unknown. METHODS A...

    journal_title：Journal of cardiovascular electrophysiology

    pub_type： 临床试验,杂志文章,多中心研究,随机对照试验

    doi：10.1046/j.1540-8167.2005.04358.x

    authors： Stein PK,Domitrovich PP,Huikuri HV,Kleiger RE,Cast Investigators.

    更新日期：2005-01-01 00:00:00

  • Acute hemodynamic effects of atrial pacing with cardiac resynchronization therapy.

    abstract：BACKGROUND:Chronotropic incompetence is common among patients with advanced heart failure (HF), thus atrial pacing (AP) is frequently utilized in this population. The hemodynamic effects of AP during cardiac resynchronization therapy (CRT) have not been well studied. OBJECTIVE:The purpose of this study was to compare ...

    journal_title：Journal of cardiovascular electrophysiology

    pub_type： 杂志文章

    doi：10.1111/j.1540-8167.2009.01460.x

    authors： Gold MR,Niazi I,Giudici M,Leman RB,Sturdivant JL,Kim MH,Waggoner AD,Ding J,Arcot-Krishnamurthy S,Daum D,Yu Y

    更新日期：2009-08-01 00:00:00

  • Acute atrial dilatation slows conduction and increases AF vulnerability in the human atrium.

    abstract：INTRODUCTION:The mechanisms by which atrial stretch favors the development of a substrate for atrial fibrillation (AF) are not fully understood. In this study, the role of stretch-induced conduction changes in the creation of a proarrhythmic substrate has been investigated by quantifying the spatial distribution of loc...

    journal_title：Journal of cardiovascular electrophysiology

    pub_type： 杂志文章

    doi：10.1111/j.1540-8167.2010.01939.x

    authors： Ravelli F,Masè M,del Greco M,Marini M,Disertori M

    更新日期：2011-04-01 00:00:00

  • Dissociated pulmonary vein arrhythmia: incidence and characteristics.

    abstract：INTRODUCTION:The incidence and characteristics of dissociated arrhythmia confined to the pulmonary vein (PV) following disconnection have not been described in a large number of patients with paroxysmal atrial fibrillation. METHODS AND RESULTS:This was a prospective study of 152 patients (29 female, mean age 51 +/- 11...

    journal_title：Journal of cardiovascular electrophysiology

    pub_type： 临床试验,杂志文章

    doi：10.1046/j.1540-8167.2003.02583.x

    authors： Weerasooriya R,Jaïs P,Scavée C,Macle L,Shah DC,Arentz T,Salerno JA,Raybaud F,Choi KJ,Hocini M,Clémenty J,Haïssaguerre M

    更新日期：2003-11-01 00:00:00

  • Effects of verapamil and ibutilide on atrial fibrillation and postfibrillation atrial refractoriness.

    abstract：INTRODUCTION:Early recurrence of atrial fibrillation (AF) after cardioversion may be related to shortening of the atrial effective refractory period (ERP). This study compared the effects of verapamil and ibutilide on AF cycle length (AFCL), atrial ERP, and susceptibility to recurrent AF. METHODS AND RESULTS:In 33 adu...

    journal_title：Journal of cardiovascular electrophysiology

    pub_type： 杂志文章

    doi：10.1046/j.1540-8167.2002.00151.x

    authors： Sticherling C,Hsu W,Tada H,Bares AC,Oral H,Pelosi F,Knight BP,Strickberger SA,Morady F

    更新日期：2002-02-01 00:00:00

  • Time course of esophageal lesions after catheter ablation with cryothermal and radiofrequency ablation: implication for atrio-esophageal fistula formation after catheter ablation for atrial fibrillation.

    abstract：BACKGROUND:Atrio-esophageal fistulas have been described as a consequence of radiofrequency (RF) ablation for the treatment of atrial fibrillation (AF). However, whether cryoablation can avoid this potential fatal complication remains unclear. METHODS AND RESULTS:We studied the effects of direct application of RF and ...

    journal_title：Journal of cardiovascular electrophysiology

    pub_type： 杂志文章

    doi：10.1111/j.1540-8167.2007.00790.x

    authors： Ripley KL,Gage AA,Olsen DB,Van Vleet JF,Lau CP,Tse HF

    更新日期：2007-06-01 00:00:00

  • Compound motor action potential guided 240 seconds plus bonus freeze for safe and durable left atrial appendage isolation in patients with recurrent persistent atrial fibrillation: How to isolate the appendage with cryoballoon (the CMAP guided ICE-B proto

    abstract：INTRODUCTION:Pulmonary vein isolation (PVI) is the cornerstone ablation strategy for treatment of atrial fibrillation (AF). Ablation outside the PVs is sometimes needed particularly in persistent or longstanding AF. This study reported left atrial appendage isolation (LAAI) using cryoballoon (CB) focusing on technical ...

    journal_title：Journal of cardiovascular electrophysiology

    pub_type： 杂志文章

    doi：10.1111/jce.13818

    authors： Chen S,Schmidt B,Bordignon S,Perrotta L,Bologna F,Nagase T,Chun KRJ

    更新日期：2019-02-01 00:00:00

  • Prevalence and predictors of cable extrusion and loss of electrical integrity with the Riata defibrillator lead.

    abstract：INTRODUCTION:Recently, a medical advisory was issued regarding the Riata and Riata ST silicone endocardial defibrillator leads (St. Jude Medical, Sylmar, CA, USA) addressing the issue of conductor cables extruding in an "inside-out" fashion from the main body of the lead. However, little data exist to guide our managem...

    journal_title：Journal of cardiovascular electrophysiology

    pub_type： 杂志文章

    doi：10.1111/j.1540-8167.2012.02378.x

    authors： Shen S,Bhave P,Giedrimas E,Patel T,Arora R,Chicos AB,Goldberger JJ,Ilkhanoff L,Kim MH,Lin AC,Passman R,Lee R,Knight BP,Kim SS

    更新日期：2012-11-01 00:00:00

  • Electrocardiographic optimization of interventricular delay in cardiac resynchronization therapy: a simple method to optimize the device.

    abstract：INTRODUCTION:Echocardiography is widely used to optimize CRT programming, but it is time-consuming. This study aimed to correlate the optimal interventricular pacing (V-V) interval obtained by echo with the optimal V-V interval obtained by a simpler method based on the surface ECG. METHODS AND RESULTS:Three V-V interv...

    journal_title：Journal of cardiovascular electrophysiology

    pub_type： 临床试验,杂志文章

    doi：10.1111/j.1540-8167.2007.00983.x

    authors： Vidal B,Tamborero D,Mont L,Sitges M,Delgado V,Berruezo A,Díaz-Infante E,Tolosana JM,Paré C,Brugada J

    更新日期：2007-12-01 00:00:00

  • Atrial macroreentry involving the myocardium of the coronary sinus: a unique mechanism for atypical flutter.

    abstract：:Atrial flutter involving either clockwise or counterclockwise rotation around the tricuspid annulus utilizing the subeustachian isthmus has been well described. However, macroreentrant atrial circuits in atypical atrial flutter in patients who have not undergone previous surgery or without atrial disease are not well ...

    journal_title：Journal of cardiovascular electrophysiology

    pub_type： 杂志文章

    doi：10.1111/j.1540-8167.1998.tb00886.x

    authors： Olgin JE,Jayachandran JV,Engesstein E,Groh W,Zipes DP

    更新日期：1998-10-01 00:00:00

  • Rhodiola Inhibits Atrial Arrhythmogenesis in a Heart Failure Model.

    abstract：INTRODUCTION:Rhodiola, a popular plant in Tibet, has been proven to decrease arrhythmia. The aim of this study was to elucidate the molecular mechanism and electrophysiological properties of rhodiola in the suppression of atrial fibrillation. METHODS:This study consisted of 3 groups as follows: Group 1: normal control...

    journal_title：Journal of cardiovascular electrophysiology

    pub_type： 杂志文章

    doi：10.1111/jce.13026

    authors： Liu SH,Hsiao YW,Chong E,Singhal R,Fong MC,Tsai YN,Hsu CP,Chen YC,Chen YJ,Chiou CW,Chiang SJ,Chang SL,Chen SA

    更新日期：2016-09-01 00:00:00

  • Action potential duration and QT interval during pinacidil infusion in isolated rabbit hearts.

    abstract：INTRODUCTION:Acute myocardial ischemia, which opens K(ATP) channel, is associated with shortened action potential duration (APD) but prolonged QT interval. This discrepancy has not been adequately explained. We hypothesize that the duration of intracellular calcium (Ca(i)) transient (DCaT) may play a role in determinin...

    journal_title：Journal of cardiovascular electrophysiology

    pub_type： 杂志文章

    doi：10.1111/j.1540-8167.2005.40811.x

    authors： Wu S,Hayashi H,Lin SF,Chen PS

    更新日期：2005-08-01 00:00:00

  • Cardiac electrophysiology in genetically engineered mice.

    abstract：:The mouse has become the principal animal model for studying biologic processes in mammals. Major advances in transgene and gene targeting technology enabled manipulation of the mouse genome in a predictable fashion. Mutant mouse strains provide important insights into the molecular mechanisms underlying normal and di...

    journal_title：Journal of cardiovascular electrophysiology

    pub_type： 杂志文章,评审

    doi：10.1111/j.1540-8167.2000.tb01806.x

    authors： Gehrmann J,Berul CI

    更新日期：2000-03-01 00:00:00

  • Clinical feasibility of pulmonary vein orifice pacing for the prediction of phrenic nerve injury during cryoballoon ablation of atrial fibrillation.

    abstract：INTRODUCTION:Phrenic nerve (PN) injury is a well-known complication of cryoballoon ablation (CBA) for pulmonary vein (PV) isolation in patients with atrial fibrillation. However, it is still insufficient to practically predict phrenic nerve injury (PNI) before freezing. We hypothesized that phrenic nerve capture (PNC) ...

    journal_title：Journal of cardiovascular electrophysiology

    pub_type： 杂志文章

    doi：10.1111/jce.13962

    authors： Sano M,Urushida T,Matsukura G,Sakakibara T,Suwa K,Naruse Y,Ohtani H,Saotome M,Maekawa Y

    更新日期：2019-08-01 00:00:00

  • Atrial activation mapping in sinus rhythm in the clinical electrophysiology laboratory: observations during Bachmann's bundle block.

    abstract：INTRODUCTION:The high posterolateral right atrium (RA) is considered the "sinus node area," but we lack information on endocardial atrial activation in sinus rhythm. We studied RA and left atrial (LA) endocardial activation in the electrophysiology laboratory. METHODS AND RESULTS:Thirty-five patients (21 men) aged 47 ...

    journal_title：Journal of cardiovascular electrophysiology

    pub_type： 临床试验,杂志文章

    doi：10.1046/j.1540-8167.2004.03403.x

    authors： Cosío FG,Martín-Peñato A,Pastor A,Núñez A,Montero MA,Cantale CP,Schames S

    更新日期：2004-05-01 00:00:00

  • Reduction in atrial defibrillation threshold by a single linear ablation lesion.

    abstract：INTRODUCTION:This study investigated a hybrid approach to reduce the atrial defibrillation threshold (ADFT) by determining the effect of a single linear radiofrequency ablation (RFA) lesion on both the ADFT and activation patterns during atrial fibrillation (AF). METHODS AND RESULTS:In 18 open chest sheep (45 to 57 kg...

    journal_title：Journal of cardiovascular electrophysiology

    pub_type： 杂志文章

    doi：10.1046/j.1540-8167.2001.00463.x

    authors： White JB,Fotuhi PC,Pedoto RW,Chattipakorn N,Rogers JM,Ideker RE

    更新日期：2001-04-01 00:00:00

  • Role of virtual electrodes in arrhythmogenesis: pinwheel experiment revisited.

    abstract：INTRODUCTION:Recent experimental evidence demonstrates that a point stimulus generates a nonuniform distribution of transmembrane potential (virtual electrode pattern) consisting of large adjacent areas of depolarization and hyperpolarization. This simulation study focuses on the role of virtual electrodes in reentry i...

    journal_title：Journal of cardiovascular electrophysiology

    pub_type： 杂志文章

    doi：10.1111/j.1540-8167.2000.tb01796.x

    authors： Lindblom AE,Roth BJ,Trayanova NA

    更新日期：2000-03-01 00:00:00

  • The impact of catheter ablation in the interpulmonary isthmus on atrial fibrillation ablation outcomes: a randomized study.

    abstract：INTRODUCTION:Previous studies have underscored the importance of the interpulmonary isthmus in the initiation and maintenance of atrial fibrillation (AF). The efficacy of additional radiofrequency energy delivery in the interpulmonary isthmus following pulmonary vein antral isolation (PVAI) was investigated. METHODS A...

    journal_title：Journal of cardiovascular electrophysiology

    pub_type： 杂志文章,随机对照试验

    doi：10.1111/jce.12399

    authors： Letsas KP,Efremidis M,Vlachos K,Karlis D,Lioni L,Asvestas D,Valkanas K,Mihas CC,Sideris A

    更新日期：2014-07-01 00:00:00

  • Drug-induced torsades de pointes and implications for drug development.

    abstract：:Torsades de pointes is a potentially lethal arrhythmia that occasionally appears as an adverse effect of pharmacotherapy. Recently developed understanding of the underlying electrophysiology allows better estimation of the drug-induced risks and explains the failures of older approaches through the surface ECG. This a...

    journal_title：Journal of cardiovascular electrophysiology

    pub_type： 杂志文章,评审

    doi：10.1046/j.1540-8167.2004.03534.x

    authors： Fenichel RR,Malik M,Antzelevitch C,Sanguinetti M,Roden DM,Priori SG,Ruskin JN,Lipicky RJ,Cantilena LR,Independent Academic Task Force.

    更新日期：2004-04-01 00:00:00

  • Noncontact electroanatomic mapping to characterize typical atrial flutter: participation of right atrial posterior wall in the reentrant circuit.

    abstract：BACKGROUND:Reentry utilizing cavotricuspid isthmus (CTI) is accepted as the mechanism underlying typical atrial flutter (AFLT). However, it is unclear how the right atrial (RA) posterior wall (PW) participates in AFLT circuit. We sought to investigate this by using noncontact electroanatomic mapping. METHODS:Fifteen p...

    journal_title：Journal of cardiovascular electrophysiology

    pub_type： 杂志文章

    doi：10.1111/j.1540-8167.2010.01917.x

    authors： Dixit S,Lavi N,Robinson M,Riley MP,Callans DJ,Marchlinski FE,Lin D

    更新日期：2011-04-01 00:00:00

  • Consequences of chronic frequent premature atrial contractions: Association with cardiac arrhythmias and cardiac structural changes.

    abstract：INTRODUCTION:Frequent premature ventricular contractions (PVCs) can cause cardiomyopathy (CM). Postextrasystolic potentiation (PESP) and irregularity have been in implicated as triggers of PVC-CM. Because both phenomena can also be found in premature atrial contractions (PACs), it is speculated that frequent PACs have ...

    journal_title：Journal of cardiovascular electrophysiology

    pub_type： 杂志文章

    doi：10.1111/jce.14067

    authors： Gunda S,Akyeampong D,Gomez-Arroyo J,Jovin DG,Kowlgi NG,Kaszala K,Tan AY,Koneru JN,Kron J,Ellenbogen KA,Huizar JF

    更新日期：2019-10-01 00:00:00

  • Risk stratification in asymptomatic patients with Brugada syndrome: Utility of multiple risk factor combination rather than programmed electrical stimulation.

    abstract：BACKGROUND:The prognostic value of programmed electrical stimulation (PES) in Brugada syndrome (BrS) remains controversial. Asymptomatic BrS patients generally have a better prognosis than those with symptoms. The purpose of this study was to evaluate the value of nonaggressive PES with up to two extra stimuli and pred...

    journal_title：Journal of cardiovascular electrophysiology

    pub_type： 杂志文章

    doi：10.1111/jce.14848

    authors： Shinohara T,Takagi M,Kamakura T,Sekiguchi Y,Yokoyama Y,Aihara N,Hiraoka M,Aonuma K,Japan Idiopathic Ventricular Fibrillation Study (J-IVFS) Investigators.

    更新日期：2020-12-25 00:00:00