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Dissociated pulmonary vein arrhythmia: incidence and characteristics.

Abstract：

INTRODUCTION:The incidence and characteristics of dissociated arrhythmia confined to the pulmonary vein (PV) following disconnection have not been described in a large number of patients with paroxysmal atrial fibrillation. METHODS AND RESULTS:This was a prospective study of 152 patients (29 female, mean age 51 +/- 11 years) referred for catheter ablation of drug-refractory paroxysmal atrial fibrillation. Following ostial ablation, the rate and regularity of any dissociated venous activity was analyzed with and without isoproterenol infusion (to achieve a heart rate of 120-140 beats/min). Patients then were classified according to their venous dissociated activity. Group 1 consisted of patients in whom the dissociated PV spike had a slow rhythm >1,200 ms. Group 2 consisted of patients with spontaneous repetitive dissociated discharges confined in the vein with a cycle length <400 ms. A total of 384 PVs were ablated in 152 patients. Disappearance of all venous potentials was observed in 88% of the treated veins; at least one dissociated venous potential was observed in the remaining 12%. Group 1 activity was seen more often than group 2 (23 patients, mean cycle length 2,300 +/- 1,100 ms vs 13 patients, mean cycle length 179 +/- 77 ms). Dissociated PV arrhythmia was seen most often in the right superior PV (19%). CONCLUSION:Dissociation as the endpoint of PV disconnection was observed in 12% of PVs. Due to the capricious nature of this activity, the actual incidence is almost certainly higher. The dissociated venous rhythm usually is slow and, less commonly, is rapid and repetitive.

journal_name

J Cardiovasc Electrophysiol

journal_title

Journal of cardiovascular electrophysiology

authors

Weerasooriya R,Jaïs P,Scavée C,Macle L,Shah DC,Arentz T,Salerno JA,Raybaud F,Choi KJ,Hocini M,Clémenty J,Haïssaguerre M

doi

10.1046/j.1540-8167.2003.02583.x

keywords:

subject

Has Abstract

pub_date

2003-11-01 00:00:00

pages

1173-9

issue

11

eissn

1045-3873

issn

1540-8167

journal_volume

14

pub_type

临床试验,杂志文章

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