Abstract:
INTRODUCTION:Advanced age is reported to be associated with lower survival after out-of-hospital cardiac arrest (OHCA). We aimed to establish survival rate and neurological outcome at hospital discharge after OHCA in older patients and evaluated whether pre-OHCA comorbidity was associated with favorable neurologic outcome. METHODS:From a prospective registry of all cardiopulmonary resuscitation (CPR) attempts after OHCA, we established survival in 1332 patients aged ≥ 70 years in whom resuscitation with non-traumatic etiology was attempted in 2009-2011. Pre-OHCA factors (age, gender, residing in long-term care institution, Charlson Comorbidity Index [CCI] score) and resuscitation parameters (initial rhythm, bystander witnessed, bystander CPR and time to defibrillator connection) with survival at hospital discharge with favorable neurologic outcome were regressed in the 851 patients of whom CCI was known. RESULTS:We found a 12% survival to discharge rate in patients aged ≥ 70 years (70-79 years: 16%; ≥ 80 years: 8%, p=0.001). Among surviving patients, 90% survived with favorable neurologic outcome. In a model with only pre-OHCA factors age was significantly associated with outcome (age OR 0.94, 95%CI 0.91-0.98), p = 0.003). High CCI score (≥ 4) was not statistically significant when associated with survival (7% vs. 12%, OR 0.53, 95%CI (0.25-1.13), p = 0.10). When adjusted for resuscitation parameters, OR for high CCI was 0.71 (95% CI 0.28-1.80, p = 0.47), also none of the other pre-OHCA factors remained statistically significant. CONCLUSION:In the Netherlands, the survival rate in older patients was 12%; the great majority survived with favorable neurologic outcome. Resuscitation-related factors and not comorbidity determine outcome after OHCA in older patients.
journal_name
Resuscitationjournal_title
Resuscitationauthors
Beesems SG,Blom MT,van der Pas MH,Hulleman M,van de Glind EM,van Munster BC,Tijssen JG,Tan HL,van Delden JJ,Koster RWdoi
10.1016/j.resuscitation.2015.06.017subject
Has Abstractpub_date
2015-09-01 00:00:00pages
33-9eissn
0300-9572issn
1873-1570pii
S0300-9572(15)00263-4journal_volume
94pub_type
杂志文章相关文献
RESUSCITATION文献大全abstract:AIM:The emergency department (ED) is an area where major airway difficulties can occur, often as complications of rapid sequence induction (RSI). We undertook a prospective, observational study of tracheal intubation performed in a large, urban UK ED to study this further. METHODS:We reviewed data on every intubation ...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2015.01.005
更新日期:2015-04-01 00:00:00
abstract::Management of patients in cardiopulmonary arrest is challenging and can be resource consuming. Outcomes continue to be poor and physicians may feel a sense of futility when running a resuscitation. Bedside ultrasound has been utilized to guide resuscitations, diagnose correctable cardiac pathology leading to an arrest...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2008.02.021
更新日期:2008-08-01 00:00:00
abstract::The haemodynamic effects of variations in the compression-decompression frequency, 60, 90 and 120 min(-1) during ACD-CPR, were tested in a randomized cross-over design during ventricular fibrillation (VF) in 12 anaesthetized pigs (17-22 kg) using an automatic hydraulic chest compression-decompression device. There wer...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/s0300-9572(98)00139-7
更新日期:1998-12-01 00:00:00
abstract::We studied cardiovascular changes and neurologic outcome at 72 h in 42 healthy dogs after normothermic ventricular fibrillation cardiac arrest (no blood flow) of 7.5, 10, or 12.5 min duration, reversed by standard external cardiopulmonary resuscitation (CPR) (< or = 10 min) and followed by controlled ventilation to 20...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/0300-9572(93)90003-9
更新日期:1993-02-01 00:00:00
abstract::The forensic records were reviewed of 1823 deaths referred to Edinburgh City Mortuary for autopsy over a 15-month period, 2000-2001; 499 cases (343 males, 156 females) that received CPR prior to death were studied. Rib fractures were found in 29%, sternal fracture in 14%, and 11% of cases showed external chest wall br...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2004.07.005
更新日期:2004-12-01 00:00:00
abstract:AIM OF THE STUDY:Many hospitals have basic life support (BLS) training programmes, but the effects on the quality of chest compressions are unclear. This study aimed to evaluate the no-flow fraction (NFF) during BLS provided by standard care nursing teams over a five-year observation period during which annual particip...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2014.03.046
更新日期:2014-07-01 00:00:00
abstract::Public access defibrillation (PAD) is a promising strategy to fight sudden cardiac death. The Austrian Red Cross provided automated external defibrillators (AEDs) and basic life support (BLS) training as an "all inclusive package" combined with on site consultation and maintenance with annual retraining as a part of a...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2005.07.026
更新日期:2006-05-01 00:00:00
abstract:AIM:In sick children who are unable to be weighed estimation of weight is often required, but the routinely used equations lack accuracy and precision. This study aimed to develop a novel equation (Children's European Estimator of Weight-CEEW) using measurements of mid-upper arm circumference (MUAC) and other predictor...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2017.04.025
更新日期:2017-08-01 00:00:00
abstract::The mechanism for the hemorrhage-induced drop in body temperature is unknown. This study determined the alterations in cutaneous heat exchange and metabolic heat production caused by a moderate hemorrhage in conscious rats. Chronically instrumented rats were subjected to a 16 ml/kg hemorrhage, followed by a 4-h recove...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/s0300-9572(99)00169-0
更新日期:2000-04-01 00:00:00
abstract::Respiratory distress, from severe gastric aspiration pneumonitis and abdominal distention in the patient with tracheoesophageal fistula frequently requires mechanical ventilatory support. Bulk flow ventilation can lead to enlargement of the fistulous tract, elevation of gastric intraluminal pressures, raised airway pr...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/0300-9572(85)90001-2
更新日期:1985-03-01 00:00:00
abstract::Recent reports suggest that endorphins may contribute to hemodynamic depression in septic and hemorrhagic shock. There is also evidence that reversal of endorphin effects with high dose naloxone may improve hemodynamic function and improve survival in shock states. The purpose of this study was to examine the effects ...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/0300-9572(86)90076-6
更新日期:1986-07-01 00:00:00
abstract:OBJECTIVES:To establish a uniform framework describing the system and organisation of emergency medical response centres and the process of emergency medical dispatching (EMD) when reporting results from studies in emergency medicine and prehospital care. DESIGN AND RESULTS:In September 2005 a task force of 22 experts...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2008.07.007
更新日期:2008-11-01 00:00:00
abstract:OBJECTIVE:This study aimed to determine whether cardiopulmonary resuscitation (CPR) volume is associated with survival to discharge rate for out-of hospital cardiac arrest (OHCA) victims. METHODS:This study was performed in an emergency medical service (EMS) system with single-tiered basic to intermediate service leve...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2010.08.031
更新日期:2011-01-01 00:00:00
abstract::The completeness of brain ischemia with a multi-arterial clamping method in dogs was examined using EEG, evoked potentials (EPs) and vessel staining with Evans blue. EEG was monitored by bipolar parietal lead. EPs stimulating electrodes were inserted into the first thoracic (T1) epidural space and recording electrodes...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/0300-9572(91)90031-s
更新日期:1991-12-01 00:00:00
abstract:BACKGROUND:Although early shock with an automated external defibrillator (AED) is one of the several key elements to save out-of-hospital cardiac arrest (OHCA) victims, it is not always easy to find and retrieve a nearby AED in emergency settings. We developed a cell phone web system, the Mobile AED Map, displaying nea...
journal_title:Resuscitation
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.resuscitation.2010.09.466
更新日期:2011-01-01 00:00:00
abstract::Despite recent advances in its management, the outcome from cardiac arrest is often poor despite appropriate cardiopulmonary resuscitation (CPR). The coronary perfusion pressure (CPP) achieved during CPR is associated with successful return of spontaneous circulation (ROSC). Continuous balloon occlusion of the descend...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2008.10.017
更新日期:2009-02-01 00:00:00
abstract:BACKGROUND:The most common etiology of cardiac arrest is presumed of myocardial origin. Recent retrospective studies indicate that preexisting pneumonia, a form of sepsis, is frequent in patients who decompensate with abrupt cardiac arrest without preceding signs of septic shock, respiratory failure or severe metabolic...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2013.09.022
更新日期:2014-02-01 00:00:00
abstract::ATP-MgCl2 treatment has been found to be a promising intervention in many models of hypoxic/ischemic injury. In this study, the effect of pre-treatment with ATP-MgCl2 on the hemodynamic response to asphyxia in the rat was examined. Rats were anesthetized with halothane and N2O2. A tracheostomy and femoral artery and v...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/0300-9572(93)90089-9
更新日期:1993-04-01 00:00:00
abstract:OBJECTIVES:The main pathogenesis of acute lung injury induced by haemorrhagic shock is inflammation. BML-111, a lipoxinA(4)-receptor agonist, promotes acute inflammatory resolution. We sought to elucidate whether BML-111 protects haemorrhagic shock-induced acute lung injury in rats. METHODS:Thirty two adult male rats ...
journal_title:Resuscitation
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.resuscitation.2011.12.035
更新日期:2012-07-01 00:00:00
abstract:AIM OF THE STUDY:To determine the predictive power of the out-of-hospital cardiac arrest (OHCA) score and serum neuron-specific enolase (NSE) in patients resuscitated from ventricular fibrillation treated with therapeutic hypothermia (TH) and glucose control. METHODS:An analysis of prospectively collected data of 90 T...
journal_title:Resuscitation
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.resuscitation.2008.08.017
更新日期:2009-02-01 00:00:00
abstract:INTRODUCTION:Optimal paddle force minimises transthoracic impedance; a factor associated with increased defibrillation success. Optimal force for the defibrillation of children < or =10 kg using paediatric paddles has previously been shown to be 2.9 kgf, and for children >10 kg using adult paddles is 5.1 kgf. We compar...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2003.09.001
更新日期:2004-01-01 00:00:00
abstract:SETTING:Sudden Cardiac Death accounts for approximately 5000 deaths in Ireland each year. Nationally, out-of-hospital cardiac arrest has a very low resuscitation rate, reported at less than 5%. Ireland has a well developed general practice network which routinely manages emergencies arising in the community setting. Ho...
journal_title:Resuscitation
pub_type: 杂志文章,多中心研究
doi:10.1016/j.resuscitation.2009.07.010
更新日期:2009-11-01 00:00:00
abstract:INTRODUCTION:In various motion pictures, medical TV shows and internet chatrooms, non-medical devices were presented as tools for life-saving cricothyroidotomies. However, there is uncertainty about whether it is possible for a bystander to perform a cricothyroidotomy and maintain gas exchange using improvised househol...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2016.10.015
更新日期:2017-01-01 00:00:00
abstract:AIM:In animal and human studies, measuring the pressure of end tidal carbon dioxide (P(ET)CO2) has been shown to be a practical non-invasive method that correlates well with the pulmonary blood flow and cardiac output (CO) generated during cardiopulmonary resuscitation (CPR). This study aims to compare mechanical activ...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2009.08.006
更新日期:2009-10-01 00:00:00
abstract:BACKGROUND:Public access of automated external defibrillator (AED) is an important public health strategy for improving survival of cardiac arrest. Major metropolitan cities in China are increasingly investing and implementing public access defibrillator programs, but the effectiveness of these programs remains unclear...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2019.05.015
更新日期:2019-07-01 00:00:00
abstract:BACKGROUND AND AIM:Unsuccessful defibrillation shocks adversely affect survival from out-of-hospital cardiac arrest (OHCA). Ventricular fibrillation (VF) waveform analysis is the tool-of-choice for the non-invasive prediction of shock success, but surrogate markers of perfusion like end-tidal CO2 (EtCO2) could improve ...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2019.02.028
更新日期:2019-05-01 00:00:00
abstract::If sudden cardiac arrest occurs during cardiac catheterization, the underlying coronary condition may be defined immediately by coronary angiography. This may, in turn, allow a lifesaving attempt of percutaneous coronary intervention (PCI). We report on two patients with critical proximal disease of the left coronary ...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2003.12.020
更新日期:2004-05-01 00:00:00
abstract:BACKGROUND:Point-of-care ultrasound has been suggested to improve outcomes from advanced cardiac life support (ACLS), but no large studies have explored how it should be incorporated into ACLS. Our aim was to determine whether cardiac activity on ultrasound during ACLS is associated with improved survival. METHODS:We ...
journal_title:Resuscitation
pub_type: 杂志文章,多中心研究
doi:10.1016/j.resuscitation.2016.09.018
更新日期:2016-12-01 00:00:00
abstract:UNLABELLED:The optimal intravenous catheterisation site for emergencies is unknown. The external jugular vein might be preferable route compared to cubital veins in emergencies due to more rapid circulation time to heart and faster cardiac responses. However, the feasibility of the different venous catheterisation site...
journal_title:Resuscitation
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.resuscitation.2009.08.026
更新日期:2009-12-01 00:00:00
abstract::Sudden cardiac arrest remains an important health care problem. If survival rates of all regions would equal those of the best performers, literally thousands of lives would be saved. Similar to injury, there is a need for an epidemiology-based approach for planning and execution of countermeasures. In this policy pap...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2014.01.032
更新日期:2014-05-01 00:00:00