RNA-seq analysis of an apical meristem time series reveals a critical point in Arabidopsis thaliana flower initiation.

abstract：BACKGROUND:It is believed that the main factors of low prenatal growth in mammals are genetic and environmental. We used isogenic mice maintained in standard conditions to analyze how natural non-genetic microsomia (low birth weight) is produced in inbred mice and its long term effect on health. To better understand th...

journal_title：BMC genomics

authors： Miranda A,López-Cardona AP,Laguna-Barraza R,Calle A,López-Vidriero I,Pintado B,Gutiérrez-Adán A

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:With advances in next generation sequencing technology and analysis methods, single nucleotide variants (SNVs) and indels can be detected with high sensitivity and specificity in exome sequencing data. Recent studies have demonstrated the ability to detect disease-causing copy number variants (CNVs) in exome...

journal_title：BMC genomics

authors： Samarakoon PS,Sorte HS,Stray-Pedersen A,Rødningen OK,Rognes T,Lyle R

更新日期：2016-01-14 00:00:00

abstract：BACKGROUND:Actinobacillus pleuropneumoniae causes pleuropneumonia in pigs, a disease which is associated with high morbidity and mortality, as well as impaired animal welfare. To obtain in-depth understanding of this infection, the interplay between virulence factors of the pathogen and defense mechanisms of the porcin...

journal_title：BMC genomics

authors： Brogaard L,Klitgaard K,Heegaard PM,Hansen MS,Jensen TK,Skovgaard K

更新日期：2015-05-28 00:00:00

abstract：BACKGROUND:Many biological systems respond to the presence or absence of gravity. Since experiments performed in space are expensive and can only be undertaken infrequently, Earth-based simulation techniques are used to investigate the biological response to weightlessness. A high gradient magnetic field can be used to...

journal_title：BMC genomics

authors： Herranz R,Larkin OJ,Dijkstra CE,Hill RJ,Anthony P,Davey MR,Eaves L,van Loon JJ,Medina FJ,Marco R

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:MicroRNAs (miRNAs) are a class of noncoding small RNAs (sRNAs) that are 20-24 nucleotides (nt) in length. Extensive studies have indicated that miRNAs play versatile roles in plants, functioning in processes such as growth, development and stress responses. Chilling is a common abiotic stress that seriously ...

journal_title：BMC genomics

authors： Cao X,Wu Z,Jiang F,Zhou R,Yang Z

更新日期：2014-12-17 00:00:00

abstract：BACKGROUND:The Xanthomonas citri pv. citri (X. citri) is a phytopathogenic bacterium that infects different species of citrus plants where it causes canker disease. The adaptation to different habitats is related to the ability of the cells to metabolize and to assimilate diverse compounds, including sulfur, an essenti...

journal_title：BMC genomics

authors： Pereira CT,Moutran A,Fessel M,Balan A

更新日期：2015-07-14 00:00:00

abstract：BACKGROUND:Studying functional divergences between paralogs that originated from genome duplication is a significant topic in investigating molecular evolution. Genes that exhibit basal level cyclic expression patterns including circadian and light responsive genes are important physiological regulators. Temporal shift...

journal_title：BMC genomics

authors： Lu Y,Boswell M,Boswell W,Salinas RY,Savage M,Reyes J,Walter S,Marks R,Gonzalez T,Medrano G,Warren WC,Schartl M,Walter RB

更新日期：2020-11-11 00:00:00

abstract：BACKGROUND:Post-translational glycosylation of the flagellin protein is relatively common among Gram-negative bacteria, and has been linked to several phenotypes, including flagellar biosynthesis and motility, biofilm formation, host immune evasion and manipulation and virulence. However to date, despite extensive phys...

journal_title：BMC genomics

authors： De Maayer P,Cowan DA

更新日期：2016-05-20 00:00:00

abstract：BACKGROUND:Understanding polyphenism, the ability of a single genome to express multiple morphologically and behaviourally distinct phenotypes, is an important goal for evolutionary and developmental biology. Polyphenism has been key to the evolution of the Hymenoptera, and particularly the social Hymenoptera where the...

journal_title：BMC genomics

authors： Colgan TJ,Carolan JC,Bridgett SJ,Sumner S,Blaxter ML,Brown MJ

更新日期：2011-12-20 00:00:00

abstract：BACKGROUND:Viruses have unique properties, small genome and regions of high similarity, whose effects on metagenomic assemblies have not been characterized so far. This study uses diverse in silico simulated viromes to evaluate how extensively genomes can be assembled using different sequencing platforms and assemblers...

journal_title：BMC genomics

authors： Aguirre de Cárcer D,Angly FE,Alcamí A

更新日期：2014-11-18 00:00:00

abstract：BACKGROUND:Many transcripts have been generated due to the development of sequencing technologies, and lncRNA is an important type of transcript. Predicting lncRNAs from transcripts is a challenging and important task. Traditional experimental lncRNA prediction methods are time-consuming and labor-intensive. Efficient ...

journal_title：BMC genomics

authors： Xu Y,Zhao X,Liu S,Zhang W

更新日期：2020-12-17 00:00:00

abstract：BACKGROUND:Sugarcane (Saccharum spp.) is predominantly an autopolyploid plant with a variable ploidy level, frequent aneuploidy and a large genome that hampers investigation of its organization. Genetic architecture studies are important for identifying genomic regions associated with traits of interest. However, due t...

journal_title：BMC genomics

authors： Balsalobre TW,da Silva Pereira G,Margarido GR,Gazaffi R,Barreto FZ,Anoni CO,Cardoso-Silva CB,Costa EA,Mancini MC,Hoffmann HP,de Souza AP,Garcia AA,Carneiro MS

更新日期：2017-01-11 00:00:00

abstract：BACKGROUND:Genome-wide association studies (GWAS) have identified many common polymorphisms associated with complex traits. However, these associated common variants explain only a small fraction of the phenotypic variances, leaving a substantial portion of genetic heritability unexplained. As a result, searches for "m...

journal_title：BMC genomics

authors： Chen Q,Sun F

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:The food spoilage yeast species Zygosaccharomyces bailii exhibits an extraordinary capacity to tolerate weak acids, in particular acetic acid. In Saccharomyces cerevisiae, the transcription factor Haa1 (ScHaa1) is considered the main player in genomic expression reprogramming in response to acetic acid stres...

journal_title：BMC genomics

authors： Palma M,Dias PJ,Roque FC,Luzia L,Guerreiro JF,Sá-Correia I

更新日期：2017-01-13 00:00:00

abstract：BACKGROUND:The numerous classes of repeats often impede the assembly of genome sequences from the short reads provided by new sequencing technologies. We demonstrate a simple and rapid means to ascertain the repeat structure and total size of a bacterial or archaeal genome without the need for assembly by directly anal...

journal_title：BMC genomics

authors： Williams D,Trimble WL,Shilts M,Meyer F,Ochman H

更新日期：2013-08-08 00:00:00

abstract：BACKGROUND:Sequencing data has become a standard measure of diverse cellular activities. For example, gene expression is accurately measured by RNA sequencing (RNA-Seq) libraries, protein-DNA interactions are captured by chromatin immunoprecipitation sequencing (ChIP-Seq), protein-RNA interactions by crosslinking immun...

journal_title：BMC genomics

authors： Kucukural A,Yukselen O,Ozata DM,Moore MJ,Garber M

更新日期：2019-01-05 00:00:00

abstract：BACKGROUND:Colletotrichum graminicola and C. sublineola cause anthracnose leaf and stalk diseases of maize and sorghum, respectively. In spite of their close evolutionary relationship, the two species are completely host-specific. Host specificity is often attributed to pathogen virulence factors, including specialized...

journal_title：BMC genomics

authors： Buiate EAS,Xavier KV,Moore N,Torres MF,Farman ML,Schardl CL,Vaillancourt LJ

更新日期：2017-01-10 00:00:00

abstract：BACKGROUND:Aspartic proteases are known to play an important role in the biology of nematode parasitism. This role is best characterised in blood-feeding nematodes, where they digest haemoglobin, but they are also likely to play important roles in the biology of nematode parasites that do not feed on blood. In the pres...

journal_title：BMC genomics

authors： Mello LV,O'Meara H,Rigden DJ,Paterson S

更新日期：2009-12-16 00:00:00

abstract：BACKGROUND:The sacred lotus (Nelumbo nucifera) is widely cultivated in China for its edible rhizomes and seeds. Traditional plant breeding methods have been used to breed cultivars with increased yields and quality of rhizomes and seeds with limited success. Currently, the available genetic maps and molecular markers i...

journal_title：BMC genomics

authors： Liu Z,Zhu H,Liu Y,Kuang J,Zhou K,Liang F,Liu Z,Wang D,Ke W

更新日期：2016-06-17 00:00:00

abstract：BACKGROUND:Compromised intestinal barrier (CIB) has been associated with many enteropathies, including colorectal cancer (CRC) and inflammatory bowel disease (IBD). We hypothesized that CIB could lead to increased host-derived contents including epithelial cells into the gut, change its physio-metabolic properties, and...

journal_title：BMC genomics

authors： Jiang P,Lai S,Wu S,Zhao XM,Chen WH

更新日期：2020-05-11 00:00:00

abstract：BACKGROUND:An organism can respond to changing environmental conditions by adjusting gene regulation and by forming alternative phenotypes. In nematodes, these mechanisms are coupled because many species will form dauer larvae, a stress-resistant and non-aging developmental stage, when exposed to unfavorable environmen...

journal_title：BMC genomics

authors： Sinha A,Sommer RJ,Dieterich C

更新日期：2012-06-19 00:00:00

abstract：BACKGROUND:RNA-Seq is now widely used as a research tool. Choices must be made whether to use paired-end (PE) or single-end (SE) sequencing, and whether to use strand-specific or non-specific (NS) library preparation kits. To date there has been no analysis of the effect of these choices on identifying differentially e...

journal_title：BMC genomics

authors： Corley SM,MacKenzie KL,Beverdam A,Roddam LF,Wilkins MR

更新日期：2017-05-23 00:00:00

abstract：BACKGROUND:Cultivated peanut (Arachis hypogaea L.) is an important oil and protein crop, but it has low disease resistance; therefore, it is important to reveal the number, sequence features, function, and evolution of genes that confer resistance. Nucleotide-binding site-leucine-rich repeats (NBS-LRRs) are resistance ...

journal_title：BMC genomics

authors： Song H,Guo Z,Hu X,Qian L,Miao F,Zhang X,Chen J

更新日期：2019-11-13 00:00:00

abstract：BACKGROUND:Hemolymph plays key roles in honey bee molecule transport, immune defense, and in monitoring the physiological condition. There is a lack of knowledge regarding how the proteome achieves these biological missions for both the western and eastern honey bees (Apis mellifera and Apis cerana). A time-resolved pr...

journal_title：BMC genomics

authors： Feng M,Ramadan H,Han B,Fang Y,Li J

更新日期：2014-07-05 00:00:00

abstract：BACKGROUND:Williams syndrome transcription factor (WSTF) is a multifaceted protein that is involved in several nuclear processes, including replication, transcription, and the DNA damage response. WSTF participates in a chromatin-remodeling complex with the ISWI ATPase, SNF2H, and is thought to contribute to the mainte...

journal_title：BMC genomics

authors： Culver-Cochran AE,Chadwick BP

更新日期：2013-10-29 00:00:00

abstract：BACKGROUND:Species of the family Vibrionaceae are ubiquitous in marine environments. Several of these species are important pathogens of humans and marine species. Evidence indicates that genetic exchange plays an important role in the emergence of new pathogenic strains within this family. Data from the sequenced geno...

journal_title：BMC genomics

authors： Lilburn TG,Gu J,Cai H,Wang Y

更新日期：2010-06-10 00:00:00

abstract：BACKGROUND:Understanding the basis for volatile organic compound (VOC) biosynthesis and regulation is of great importance for the genetic improvement of fruit flavor. Lactones constitute an essential group of fatty acid-derived VOCs conferring peach-like aroma to a number of fruits including peach, plum, pineapple and ...

journal_title：BMC genomics

authors： Sánchez-Sevilla JF,Cruz-Rus E,Valpuesta V,Botella MA,Amaya I

更新日期：2014-04-17 00:00:00

abstract：BACKGROUND:The transformation of a developing epithelium into an adult structure is a complex process, which often involves coordinated changes in cell proliferation, metabolism, adhesion, and shape. To identify genetic mechanisms that control epithelial differentiation, we analyzed the temporal patterns of gene expres...

journal_title：BMC genomics

authors： O'Keefe DD,Thomas SR,Bolin K,Griggs E,Edgar BA,Buttitta LA

更新日期：2012-09-20 00:00:00

abstract：BACKGROUND:Cultivated watermelon [Citrullus lanatus (Thunb.) Matsum. & Nakai var. lanatus] is an important agriculture crop world-wide. The fruit of watermelon undergoes distinct stages of development with dramatic changes in its size, color, sweetness, texture and aroma. In order to better understand the genetic and m...

journal_title：BMC genomics

authors： Guo S,Liu J,Zheng Y,Huang M,Zhang H,Gong G,He H,Ren Y,Zhong S,Fei Z,Xu Y

更新日期：2011-09-21 00:00:00

abstract：BACKGROUND:Winter-ulcer Moritella viscosa infections continue to be a significant burden in Atlantic salmon (Salmo salar L.) farming. M. viscosa comprises two main clusters that differ in genetic variation and phenotypes including virulence. Horizontal gene transfer through acquisition and loss of mobile genetic elemen...

journal_title：BMC genomics

authors： Karlsen C,Hjerde E,Klemetsen T,Willassen NP

更新日期：2017-04-20 00:00:00