Genetic disorders with heterotopic ossificans.

Abstract:

:Fibrodysplasia ossificans progressiva (FOP) and progressive ossific heteroplasia (POH) are rare genetic disorders characterized by heterotopic bone formation leading to progressive loss of mobility and function. We report three cases of these rare disorders (two cases of FOP and one case of POH), which were clinically diagnosed and underwent genetic analysis. The aim of this report is to highlight the clinical features and the differences between these two conditions. We would also like to emphasize on the morbidity that can arise from unnecessary invasive investigations for diagnostic purposes.

journal_name

Indian J Orthop

authors

Sankar R,Gowrishankar K,Viswanathan S

doi

10.4103/0019-5413.156228

subject

Has Abstract

pub_date

2015-05-01 00:00:00

pages

361-4

issue

3

eissn

0019-5413

issn

1998-3727

pii

IJOrtho-49-361

journal_volume

49

pub_type

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