Endocrine mucin-producing sweat gland carcinoma: a study of three cases and CK8, CK18 and CD5/6 immunoexpression.

abstract：:Post-transplant lymphoproliferative disorder (PTLD) is a lymphoid proliferation that develops as a complication of solid organ or bone marrow transplants. PTLD limited to the skin is very rare. Plasmacytoma-like PTLD is an uncommon variant of monomorphic PTLD. Its presentation in the skin is extraordinary with very fe...

journal_title：Journal of cutaneous pathology

authors： Molina-Ruiz AM,Pulpillo A,Lasanta B,Zulueta T,Andrades R,Requena L

更新日期：2012-07-01 00:00:00

abstract：:We first report a case of granular cell histiocytosis occurring as a solitary polypoid lesion of the nipple in a 15-year-old girl. Histologically, the lesion was composed of a dermal population of medium- to large-sized, short spindle- to round- to epithelioid-shaped cells with eosinophilic cytoplasm containing numero...

journal_title：Journal of cutaneous pathology

authors： Caltabiano R,Magro G,Vecchio GM,Lanzafame S

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:The histopathologic features of tinea vary widely and its diagnosis could be easily missed if the index of suspicion is not high. We aimed in this study to detect histopathologic features that could be a clue for diagnosis METHODS:We retrospectively reviewed 103 cases of tinea, confirmed by Periodic acid-Sc...

journal_title：Journal of cutaneous pathology

authors： Elbendary A,Valdebran M,Gad A,Elston DM

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Hobnail hemangioma (targetoid hemosiderotic hemangioma) is a small benign vascular tumor of the superficial and mid-dermis. In contrast to its well-characterized histology, it has been unclear whether this tumor arises from blood vessel endothelial cells (BECs) or lymphatic vessel endothelial cells (LECs). ...

journal_title：Journal of cutaneous pathology

authors： Franke FE,Steger K,Marks A,Kutzner H,Mentzel T

更新日期：2004-05-01 00:00:00

abstract：:Biopsies from a 5-year-old girl with dermatomyositis and universal calcinosis were studied histopathologically and by means of electron optical techniques. The dermis was infiltrated by fibroblasts, lymphocytes and plasma cells. In the lower part of the dermis, dense basophilic areas were present. In the vicinity of t...

journal_title：Journal of cutaneous pathology

authors： Nielsen AO,Johnson E,Hentzer B,Kobayasi T

更新日期：1979-12-01 00:00:00

abstract：:Rare epithelial structures in benign nerve sheath tumors are almost always glandular in appearance. We describe a case of intraoral plexiform schwannoma with concurrent squamous epithelial hyperplasia. The lesion occurred as a pigmented nodule on the gingiva of a 35-year-old woman with no systemic involvement. Histolo...

journal_title：Journal of cutaneous pathology

authors： Ide F,Muramatsu T,Kikuchi K,Saito I,Kusama K

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Infection with parvovirus B19 (B19) has been associated with connective tissue disease (CTD) stigmata, namely, a systemic lupus erythematosus (SLE)-like illness, seronegative polyarthritis resembling rheumatoid arthritis, and vasculitis. The dermatopathology and pathogenetic basis of such B19-associated CTD-...

journal_title：Journal of cutaneous pathology

authors： Crowson AN,Magro CM,Dawood MR

更新日期：2000-11-01 00:00:00

abstract：:Two cases of tubular apocrine adenoma were studied by light, histochemical, and electron microscopic methods. This benign apocrine hamartoma must be considered in the classification of appendage tumors, particularly those associated with organoid epithelial nevus, and may be confused with metastatic adenocarcinoma. Th...

journal_title：Journal of cutaneous pathology

authors： Umbert P,Winkelmann RK

更新日期：1976-01-01 00:00:00

abstract：:The plasma membrane ultrastructure of the extramammary Paget cells was characterized by freeze-fracture electron microscopy, which was first employed for the study of Paget cells. The Paget cell plasma membrane revealed a flat fractured plane with much fewer and smaller desmosome-particle aggregations than those of th...

journal_title：Journal of cutaneous pathology

authors： Kitajima Y,Mori S

更新日期：1980-12-01 00:00:00

abstract：:Dermatofibrosarcoma protuberans is a low-grade sarcoma of the skin with well characterized clinical and histopathological features. The lesion frequently appears as a plaque on the trunk or on the extremities of middle-aged adults. Microscopically, the tumor is composed of monomorphous spindle cells arranged in storif...

journal_title：Journal of cutaneous pathology

authors： Diaz-Cascajo C,Weyers W,Borghi S

更新日期：1998-09-01 00:00:00

abstract：:Folliculo-sebaceous hamartomas comprise a series of entities whose boundaries are imprecise. We present the clinical case of a folliculo-sebaceous cystic hamartoma of genital localization where the diagnosis was established based on the epithelial proliferation, but mostly, on the characteristic stroma. Because this l...

journal_title：Journal of cutaneous pathology

authors： Alegría-Landa V,Jo-Velasco M,Prieto-Torres L,Requena L

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:We encountered a distinctive pattern of dysplastic intraepidermal melanocytic proliferation, which defies classification as a dysplastic melanocytic nevus, but in which the morphologic features fall short of a diagnosis of melanoma in situ. We designate such lesions as de novo intraepidermal epithelioid mela...

journal_title：Journal of cutaneous pathology

authors： Sachdeva M,Frambach GE,Crowson AN,Deng AC,Mihm MC Jr,Magro CM

更新日期：2005-10-01 00:00:00

abstract：:We report the case of a 51-year-old man with an asymptomatic indurated plaque on the chest wall that was surgically excised and submitted for histopathological examination. Microscopically, the dermis was occupied by a neoplastic process with spindle-shaped cells arranged in longitudinal fascicles with cytologic atypi...

journal_title：Journal of cutaneous pathology

authors： Berzal-Cantalejo F,Sabater-Marco V,Pérez-Vallés A,Martorell-Cebollada M

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Cutaneous manifestations of B-cell chronic lymphocytic leukemia (B-CLL) comprise a wide spectrum of clinicopathologic presentations. In some cases, onset of skin lesions is triggered by antigenic stimulation, and specific skin infiltrates at sites of previous herpes simplex or herpes zoster infection have be...

journal_title：Journal of cutaneous pathology

authors： Cerroni L,Höfler G,Bäck B,Wolf P,Maier G,Kerl H

更新日期：2002-03-01 00:00:00

abstract：:We carried out a cytophotometric study of the DNA content of matrix cells from normal hair follicles and those affected by androgenetic alopecia (early and established baldness), using the Feulgen technique. We thereby obtained a 2C reference value from lymphocyte nuclei from normal skin, from which we established a 2...

journal_title：Journal of cutaneous pathology

authors： Villena A,Alcaraz MV,Pérez de Vargas I

更新日期：1994-08-01 00:00:00

abstract：:The expression and localization of connexin 43 (Cx43) were investigated in normal human epidermis, pilosebaceous apparatus, basal cell carcinoma, and squamous cell carcinoma by immunofluorescence as well as by immunoelectron microscopy. In the normal epidermis the immunofluorescence was weak in the basal layer, increa...

journal_title：Journal of cutaneous pathology

authors： Tada J,Hashimoto K

更新日期：1997-11-01 00:00:00

abstract：:The lesions of nine patients with early striae distensae (SD) during puberty were examined by light and electron microscopy. Specific changes were seen in very early stage SD, and in clinically uninvolved skin 0.5 to 3 cm remote from the edge of the long axis of the SD lesions. Sequential changes of elastolysis accomp...

journal_title：Journal of cutaneous pathology

authors： Sheu HM,Yu HS,Chang CH

更新日期：1991-12-01 00:00:00

abstract：:A 46-year-old man had a cystic mass on the right side of his scalp. Histological examination revealed a cystic dermal nodule composed of relatively circumscribed lobules of proliferating squamous epithelium, with atypical mitoses and dyskeratotic cells of invasive structure, which was diagnosed as proliferating tricho...

journal_title：Journal of cutaneous pathology

authors： Masui Y,Komine M,Kadono T,Ishiura N,Maekawa T,Ihn H,Kikuchi K,Tamaki K

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:Neurothekeoma is a benign tumor of putative peripheral nerve sheath origin. It occurs in a myxoid (classic) variant, cellular variant, and intermediate (mixed) variant. Cellular neurothekeoma (CNT) usually involves the head and neck or extremities of young patients. Histologically, CNT can be confused with m...

journal_title：Journal of cutaneous pathology

authors： Fullen DR,Lowe L,Su LD

更新日期：2003-02-01 00:00:00

abstract：:The histogenesis of atypical fibroxanthoma (AFX) and its relationship to malignant fibrous histiocytoma (MFH) are a subject of controversy. Many investigators have proposed that AFX may represent a reactive process, while others contend that it is a true fibrohistiocytic neoplasm, closely related to MFH. In an attempt...

journal_title：Journal of cutaneous pathology

authors： Worrell JT,Ansari MQ,Ansari SJ,Cockerell CJ

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND:The diagnosis of 'cellular dermal nodule in melanocytic nevi' is challenging, as it can simulate invasive and tumorigenic melanoma. Because cellular nodules are presumed benign, it is essential to differentiate them from true malignant melanoma arising within a nevus, which portends a poor prognosis. Althoug...

journal_title：Journal of cutaneous pathology

authors： Xu X,Bellucci KS,Elenitsas R,Elder DE

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:Merkel cell carcinoma (MCC) is an aggressive neoplasm, which is often associated with Merkel cell polyomavirus (MCPyV). Programmed death-1 (PD-1) and its ligand PD-L1 are key players of the tumor microenvironment (TME). METHODS:Fourteen paraffin-embedded tissue samples of MCC were stratified by their MCPyV ...

journal_title：Journal of cutaneous pathology

authors： Mitteldorf C,Berisha A,Tronnier M,Pfaltz MC,Kempf W

更新日期：2017-09-01 00:00:00

abstract：:Psoriasis is characterized by immune activation, increased proliferation and abnormal differentiation of keratinocytes. The reported anti-psoriatic mechanisms of action in vivo of vitamin D analogues include reduction of keratinocyte proliferation and induction of keratinocyte terminal differentiation. We investigated...

journal_title：Journal of cutaneous pathology

authors： Lu I,Gilleaudeau P,McLane JA,Heftler N,Kamber M,Gottlieb S,Krueger JG,Gottlieb AB

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND:To date, there has been no systematic investigation of the detailed histological features of prurigo nodularis (PN) in a large cohort of patients. METHODS:This retrospective study includes skin biopsies of 136 patients (63 males, 73 females; mean age: 58.38 years) with PN. RESULTS:Highly characteristic for...

journal_title：Journal of cutaneous pathology

authors： Weigelt N,Metze D,Ständer S

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:The use of immunohistochemical (IHC) stains in dermatopathology is commonplace; however, little is known regarding utilization trends in melanoma diagnosis. Current Medicare local coverage determinations (LCDs) state that most pigmented lesions, including melanoma, can be diagnosed using H&E alone. METHODS:...

journal_title：Journal of cutaneous pathology

authors： Dinehart MS,Dinehart SM,Sukpraprut-Braaten S,High WA

更新日期：2020-05-01 00:00:00

abstract：:Genital leiomyoma in men include those superficial leiomyomas arising in the scrotum and the areola. They are unusual neoplasms: few cases have been reported in the literature and they usually escape clinical diagnosis. Three cases of male genital leiomyomas are reported: two in the scrotum and one in the areola. They...

journal_title：Journal of cutaneous pathology

authors： Suárez-Peñaranda JM,Vieites B,Evgenyeva E,Vázquez-Veiga H,Forteza J

更新日期：2007-12-01 00:00:00

abstract：:Basic fibroblast growth factor (bFGF) is a growth factor and an angiogenesis factor which may play a role in the evolution of cutaneous malignant melanoma (CMM). In this study, we evaluated the distribution of bFGF in CMM using immunochemical methods and correlated the pattern of bFGF expression with the clinical cour...

journal_title：Journal of cutaneous pathology

authors： al-Alousi S,Barnhill R,Blessing K,Barksdale S

更新日期：1996-12-01 00:00:00

abstract：:Subungual melanoma commonly presents with solitary longitudinal melanonychia. Herein, we report the case of a patient with subungual melanoma who developed involvement of three digits by three independent primary melanomas. A 98-year-old male patient presented with a two-year history of longitudinal melanonychia on th...

journal_title：Journal of cutaneous pathology

authors： Liu Y,Wang L

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Despite its occasional unavailability, alcian blue has long been the stain of choice for the pathognomonic mucin-secreting cells of extramammary Paget's disease. Zirconyl hematoxylin is a recently developed substitute for alcian blue, which is made from common laboratory materials. METHODS:We have stained s...

journal_title：Journal of cutaneous pathology

authors： Smith AA,Silver TM

更新日期：2003-07-01 00:00:00

abstract：:The diagnosis of a CD30+ cutaneous infiltrate is often difficult and requires clinicopathologic correlation. To further evaluate this challenge, initial clinical and histopathologic diagnoses were correlated with final clinicopathologic diagnosis in 44 cases with CD30 immunopositivity. Dermatopathologic evaluation con...

journal_title：Journal of cutaneous pathology

authors： De Souza A,Carter JB,Harris NL,Ferry JA,Duncan LM

更新日期：2015-07-01 00:00:00