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Incidence and prevalence of hepatitis c virus infection among persons who inject drugs in New York City: 2006-2013.

Abstract：

BACKGROUND:Hepatitis C virus infection is a source of significant preventable morbidity and mortality among persons who inject drugs (PWID). We sought to assess trends in hepatitis C virus (HCV) infection among PWID from 2006 to 2013 in New York City (NYC). METHODS:Annual cross-sectional surveys of PWID entering a large drug abuse treatment program were performed. Risk behavior questionnaires were administered, and HIV and HCV testing were conducted. Comparisons were made with prior prevalence and incidence estimates in 1990-1991 and 2000-2001 reflecting different periods of combined prevention and treatment efforts. RESULTS:HCV prevalence among PWID (N: 1535) was 67% (95% CI: 66-70%) during the study period, and was not significantly different from that observed in 2000-2001. The estimated HCV incidence among new injectors (persons injecting for ≤6 years) during 2006-2013 was 19.5/100 PYO (95% CI: 17-23) and did not differ from that observed in 2000-2001 (18/100 PYO, 95% CI: 14-23/100). CONCLUSIONS:Despite the expansion of combined prevention programming between 2000-2001 and 2006-2013, HCV prevalence remained high. Estimated HCV incidence among new injectors also remained high, and not significantly lower than in 2000-2001, indicating that expanded combined prevention efforts are needed to control the HCV epidemic among PWID in NYC.

journal_name

Drug Alcohol Depend

journal_title

Drug and alcohol dependence

authors

Jordan AE,Des Jarlais DC,Arasteh K,McKnight C,Nash D,Perlman DC

doi

10.1016/j.drugalcdep.2015.03.039

subject

Has Abstract

pub_date

2015-07-01 00:00:00

pages

194-200

eissn

0376-8716

issn

1879-0046

pii

S0376-8716(15)00195-7

journal_volume

152

pub_type

杂志文章

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