Abstract:
RATIONALE AND OBJECTIVES:To assess the feasibility of 70-kVp high-pitch non-ECG-gated thoracic aortic computed tomography angiography (CTA) with 40-mL contrast agent compared to 100-kVp standard-pitch CTA with 60-mL contrast agent. MATERIALS AND METHODS:Sixty-seven patients (51 men and 16 women; mean age, 55 ± 14 years) received non-ECG-gated aortic CTA at 70 kVp, high pitch of 3.4, and 40-mL contrast agent (group A, n = 31) or CTA at 100-kVp, pitch of 1.2, and 60-mL contrast agent (group B, n = 36). Iterative reconstruction was used in all patients. For image quality assessment, CTA images were evaluated on a three-point scale and signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were calculated and compared. Furthermore, computed tomography (CT) dose index was recorded. RESULTS:Mean CT values and noise levels were higher in group A compared to group B (all P < .001), whereas SNR and CNR were lower than those in group B (all P < .001). Furthermore, the image quality of the aorta at the level of the diaphragm was lower in group A than that in group B (P < .05). However, image quality was graded as diagnostic in all patients, and motion artifacts of the aortic arch were significantly decreased in group A (P <.05). Interreader agreement was good or excellent for image quality assessment (k = 0.625-0.835). The 70-kVp CTA protocol, which allows dose reduction of 85%, was considered diagnostic in all instances by two readers. CONCLUSIONS:Our proposed thoracic aortic CTA protocol provides diagnostic information with substantial reduction of both radiation and contrast agent doses compared to standard-pitch CTA at 100 kVp.
journal_name
Acad Radioljournal_title
Academic radiologyauthors
Zhang LJ,Zhao YE,Schoepf UJ,Mangold S,Felmly LM,Li X,Tang CX,Zhou CS,Qi L,Lu GMdoi
10.1016/j.acra.2015.03.007subject
Has Abstractpub_date
2015-07-01 00:00:00pages
890-7issue
7eissn
1076-6332issn
1878-4046pii
S1076-6332(15)00128-2journal_volume
22pub_type
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