Familial atypical multiple mole melanoma syndrome in an adult Indian male-case report and literature review.

Abstract:

:Familial atypical multiple mole melanoma syndrome (FAMMMS) is an autosomal dominant genodermatosis characterized by multiple melanocytic nevi, usually more than 50, and a family history of melanoma. It is known to be associated with carcinoma of pancreas and other malignancies involving gastrointestinal tract, breast, lung, larynx, and skin in the kindred. There is no published report of FAMMMS in dark-skinned individuals. We report a case of FAMMMS in a dark-skinned adult Indian male, who had multiple extensive nevi all over the body and oral mucosa; associated with malignant melanoma, squamous cell carcinoma (Marjolin's ulcer), and carcinoma of pancreas. His father had died of carcinoma of lung and his sister had a partial phenotypic expression. The clinical presentation of the case is discussed with review of literature.

journal_name

Indian J Dermatol

authors

Raj RC,Patil R

doi

10.4103/0019-5154.152585

subject

Has Abstract

pub_date

2015-03-01 00:00:00

pages

217

issue

2

eissn

0019-5154

issn

1998-3611

pii

IJD-60-217b

journal_volume

60

pub_type

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