Abstract:
:This paper presents an analysis of the implications of some recent studies performed to characterize uranium products from modern uranium recovery facilities important for worker protection. Assumptions about the solubility (related to the molecular species being produced) of these materials in humans are critical to properly assess radiation dose from intakes, understand chemotoxic implications, and establish protective exposure standards (airborne concentrations, limits on intake, etc.). Recent studies, as well as information in the historical professional literature, were reviewed that address the issue of solubility and related characteristics. These data are important for the design of programs for assessment of both chemical and radiological aspects of worker exposure to the products of modern uranium recovery plants (conventional uranium mills and in situ recovery plants; i.e., ISRs). The data suggest strongly that the oxide form produced by these facilities (and therefore, product solubility) is related to precipitation chemistry and thermal exposure (dryer temperature). Given the peroxide precipitation and low temperature drying methods being used at many modern uranium recovery facilities in the U.S. today, very soluble products are being produced. The dosimetric impacts of these products to the pulmonary system (except perhaps in case of an extreme acute insult) would be small, and any residual pulmonary retention beyond a month or two would most likely be too small to measure by traditional urinalysis sampling or the current state-of-the-art of natural uranium in vivo lung counting techniques. Uranium recovery plants should revisit the adequacy of current bioassay programs in the context of their process and product specifics. Workers potentially exposed to these very soluble yellowcake concentrates should have urine specimens submitted for uranium analysis on an approximately weekly basis, including analysis for the biomarkers associated with potential renal injury [e.g., glucose, lactate dehydrogenase (LDH) and protein albumen]. Additionally, implications for compliance with current U.S. Nuclear Regulatory Commission (NRC) regulations (e.g., 10 CFR20) are discussed. NRC, the applicable Agreement State agencies, and licensees need to recognize the importance of the uranium chemotoxicity versus dose relationship in the interest of worker protection.
journal_name
Health Physjournal_title
Health physicsauthors
Brown SH,Chambers DBdoi
10.1097/HP.0000000000000136subject
Has Abstractpub_date
2014-11-01 00:00:00pages
403-9issue
5eissn
0017-9078issn
1538-5159pii
00004032-201411000-00005journal_volume
107pub_type
杂志文章相关文献
HEALTH PHYSICS文献大全abstract::Power-frequency (50/60 Hz) magnetic fields produced by electric blankets are estimated from data on blanket design using a three-dimensional computer model. Maximum, minimum, and volume-average fields within human forms are presented as a function of blanket type and a number of geometric factors including body size, ...
journal_title:Health physics
pub_type: 杂志文章
doi:10.1097/00004032-199004000-00012
更新日期:1990-04-01 00:00:00
abstract::A model system was developed previously for disposal of solid laboratory waste that is both radioactive and heat sensitive, e.g., HIV. A double polypropylene bag with charcoal vent filter and absorbent was designed to meet requirements for both steam sterilization and disposal as solid radioactive waste. Earlier work ...
journal_title:Health physics
pub_type: 杂志文章
doi:10.1097/00004032-199107000-00015
更新日期:1991-07-01 00:00:00
abstract::The use of radiation has a substantial beneficial impact, particularly in the areas of medicine, energy production, basic science research, and industrial applications. Radiation protection knowledge and experience are required for acquiring and implementing scientific knowledge to protect workers, members of the publ...
journal_title:Health physics
pub_type: 杂志文章
doi:10.1097/HP.0000000000000602
更新日期:2017-02-01 00:00:00
abstract::The deployment of a radiological dispersal device (RDD) is likely to result in relatively low radiation exposure of the targeted population, insufficient to cause a severe radiation detriment. Nevertheless, due to atmospheric dispersion of the radioactive material, an urban area equaling several city blocks could be a...
journal_title:Health physics
pub_type: 杂志文章
doi:10.1097/01.hp.0000178545.02726.21
更新日期:2005-11-01 00:00:00
abstract::In the summers of 1990 and 1991, outdoor 222Rn detectors were installed for 3 mo in 78 communities across Canada. The 1990 measurements showed large regional variations with the average outdoor levels for the provinces of Manitoba (59 Bq m-3) and Saskatchewan (61 Bq m-3) exceeding the average indoor levels of 55 Bq m-...
journal_title:Health physics
pub_type: 杂志文章
doi:10.1097/00004032-199402000-00009
更新日期:1994-02-01 00:00:00
abstract::The Department of Health and Human Services (DHHS) was directed by Congress to assess the risk of thyroid cancer from 131I associated with fallout from the atmospheric testing of nuclear weapons at the Nevada Test Site. The National Cancer Institute (NCI) was requested by DHHS to address Public Law 97-414, Section 7 (...
journal_title:Health physics
pub_type: 杂志文章
doi:10.1097/00004032-199011000-00002
更新日期:1990-11-01 00:00:00
abstract::For many, the thought of terrorists detonating a dirty bomb--a radiological dispersal device--is frightening. However, the radiation health risks from such an occurrence are small. For most people directly involved, the exposure would have an estimated lifetime health risk that is comparable to the health risk from sm...
journal_title:Health physics
pub_type: 杂志文章
doi:10.1097/00004032-200402001-00013
更新日期:2004-02-01 00:00:00
abstract::The security of medical radioactive sources, both open and sealed, is an important consideration for reducing the risk of an intentional or inadvertent additional radiation dose to the public, according to the principle of keeping any additional radiation dose as low as reasonably achievable. The detection and followi...
journal_title:Health physics
pub_type: 杂志文章
doi:10.1097/HP.0000000000001245
更新日期:2020-07-01 00:00:00
abstract::The yield of chromosome aberrations (dicentric and ring chromosomes) was determined for five patients who had been extensively exposed to diagnostic x rays. Remarkably high aberration yields were obtained for each of them leading to correspondingly high equivalent whole body doses ("biological dosimetry"). The contrib...
journal_title:Health physics
pub_type: 杂志文章
doi:10.1097/00004032-199502000-00012
更新日期:1995-02-01 00:00:00
abstract::A very limited number of field experiments have been performed to assess the relative radiation detection sensitivities of commercially available equipment used to detect radioactive sources in recycled metal scrap. Such experiments require the cooperation and commitment of considerable resources on the part of vendor...
journal_title:Health physics
pub_type: 杂志文章
doi:10.1097/01.hp.0000144567.83125.00
更新日期:2005-02-01 00:00:00
abstract::Medical workers constitute the largest group of individuals occupationally exposed to radiation, and their collective dose equivalent is exceeded only by persons employed in the nuclear fuel cycle. Although medical workers have increased in number by about 50% over the past two decades, their collective dose has stead...
journal_title:Health physics
pub_type: 杂志文章
doi:10.1097/00004032-199003000-00002
更新日期:1990-03-01 00:00:00
abstract::The average absorbed dose due to DNA-bound 3H in a cell nucleus was estimated by a Monte Carlo simulation for a model nucleus which was assumed to be spheroidal. The shape of the cell nucleus was found to be of minor importance in determining the average absorbed dose. The volume of the cell nucleus was the major dose...
journal_title:Health physics
pub_type: 杂志文章
doi:10.1097/00004032-198504000-00009
更新日期:1985-04-01 00:00:00
abstract::The design and performance of a positionally sensitive system for the laser read-out of dosimetric information contained in LiF chips and a specially designed composite detector having a thin LiF layer is reported. A 2 cm X 3 cm X 0.254 mm LiF layer was successfully manufactured with a glass backing; however, this was...
journal_title:Health physics
pub_type: 杂志文章
doi:10.1097/00004032-199010000-00004
更新日期:1990-10-01 00:00:00
abstract::Radioiodine released to the atmosphere from the accident at the Chernobyl nuclear power station in the spring of 1986 resulted in large-scale thyroid-gland exposure of populations in Ukraine, Belarus, and Russia. Because of the short half life of 131I (8.04 d), adequate data on the intensities and patterns of iodine d...
journal_title:Health physics
pub_type: 杂志文章
doi:10.1097/00004032-199611000-00015
更新日期:1996-11-01 00:00:00
abstract::Unusual reported dose equivalents due to high-energy photons for two individuals prompted the investigation of the effects of severe heating conditions expected in closed vehicles during southwestern summer months on commercial film dosimeters. A historical review of dosimetry records revealed several additional repor...
journal_title:Health physics
pub_type: 杂志文章
doi:10.1097/00004032-199104000-00018
更新日期:1991-04-01 00:00:00
abstract::This paper describes the various activities involved with opening a sealed legacy "Seventeen-inch" concrete vault and the health physics challenges and solutions employed. As part of a legacy waste stream that was removed from the former Hazardous Waste Management Facility at Brookhaven National Laboratory, the "Seven...
journal_title:Health physics
pub_type: 杂志文章
doi:10.1097/01.hp.0000156059.17528.56
更新日期:2005-05-01 00:00:00
abstract::The variability in radiosensitivity across the human population is governed in part by genetic factors. The ability to predict therapeutic response, identify individuals at greatest risk for adverse clinical responses after therapeutic radiation doses, or identify individuals at high risk for carcinogenesis from envir...
journal_title:Health physics
pub_type: 杂志文章,评审
doi:10.1097/HP.0b013e3182692085
更新日期:2012-11-01 00:00:00
abstract::With possibilities for radiation terrorism and intensified concerns about nuclear accidents since the recent Fukushima Daiichi event, the potential exposure of large numbers of individuals to radiation that could lead to acute clinical effects has become a major concern. For the medical community to cope with such an ...
journal_title:Health physics
pub_type: 杂志文章
doi:10.1097/HP.0b013e3182588d92
更新日期:2012-09-01 00:00:00
abstract::The radiation safety implications following the administration of 131I for the treatment of Grave's disease to a patient undergoing home-based renal dialysis was investigated. External dose-rate measurements from the patient revealed a peak value at around day 2, post administration. The effective half-life was determ...
journal_title:Health physics
pub_type: 杂志文章
doi:10.1097/01.HP.0000221448.21938.36
更新日期:2006-12-01 00:00:00
abstract::Delayed gamma spectrum is the fingerprint of uranium materials in arms control verification technology. The decay chain is simplified into basic state linear chain and excitation state linear chain to calculate and analyze the delayed gamma spectra of fission products. Formulas of the changing rule for nuclide number ...
journal_title:Health physics
pub_type: 杂志文章
doi:10.1097/HP.0000000000000521
更新日期:2016-07-01 00:00:00
abstract::The author was invited to talk about ICRP perceptions of a look to the future. Many questions will be addressed when the International Commission on Radiological Protection (ICRP) initiates a revision of its basic recommendations from 1977, which were published in ICRP Publication 26. This process will take several ye...
journal_title:Health physics
pub_type: 杂志文章
doi:10.1097/00004032-198808000-00004
更新日期:1988-08-01 00:00:00
abstract::Radionuclide decorporation is the only effective method of reducing radiation dose for persons contaminated accidentally. In this study, dogs that had inhaled a moderately soluble aerosol of 244Cm2O3 were treated with either discrete intravenous injections of the chelating agent diethylenetriaminepentaacetic acid (Zn-...
journal_title:Health physics
pub_type: 杂志文章
doi:10.1097/00004032-199204000-00002
更新日期:1992-04-01 00:00:00
abstract::Risk assessment of exposure to sources of radiation is an important tool for national governments in regulating radionuclide emissions and thus reducing radiation doses for the general public. For this reason radiation doses from sources throughout The Netherlands have been analyzed. For sources with well-defined loca...
journal_title:Health physics
pub_type: 杂志文章
doi:10.1097/00004032-199806000-00005
更新日期:1998-06-01 00:00:00
abstract::To estimate of the dispersion trend of 3H and 14C discharged from the Wolsung Nuclear Power Plants, the present level of 3H and 14C in environmental samples in the vicinity of the Wolsong site was studied. Tree-ring cellulose analyses were carried out for retrospective evaluation of 3H and 14C in the environment aroun...
journal_title:Health physics
pub_type: 杂志文章
doi:10.1097/00004032-200006000-00013
更新日期:2000-06-01 00:00:00
abstract::In this work, the dose to the members of the public from two different 131I thyroid ablation patient groups (1.85 GBq and 3.7 GBq), whose a priori programmed hospitalization time is 48 h, is compared. The possibility of allocating half of the hospitalization time (24 h) for patients treated with 1.85 GBq is evaluated,...
journal_title:Health physics
pub_type: 杂志文章
doi:10.1097/HP.0000000000000329
更新日期:2015-09-01 00:00:00
abstract::In the past 25 years, nuclear and radiological emergencies have occurred that cover much of the range of causes and types that had been anticipated by experts. Experience from response to these emergencies has clearly demonstrated the importance of an efficient response system that includes, among other components, em...
journal_title:Health physics
pub_type: 杂志文章,评审
doi:10.1097/01.HP.0000281176.42257.b8
更新日期:2007-11-01 00:00:00
abstract::Radiations accidents involving high exposures require accurate assessment of radiation dose for correct surgical or medical management. Techniques involving computed tomography and antimyosin-antibody scintigraphy were evaluated in an experimental model of acute localized irradiation overexposure to 192Ir. Ten rabbits...
journal_title:Health physics
pub_type: 杂志文章
doi:10.1097/00004032-200001000-00009
更新日期:2000-01-01 00:00:00
abstract::Elsewhere in this issue, Robin Elliott outlined a successful program for performing annual radiation safety management program audits. The results of such audits provide a useful means of evaluating and correcting deficiencies or weaknesses in a radiation safety program. At our institution we also perform an annual au...
journal_title:Health physics
pub_type: 杂志文章
doi:10.1097/00004032-199911001-00003
更新日期:1999-11-01 00:00:00
abstract::With present-day rapid increases in the applications of radiofrequency microwave radiation in research, medicine, defense, communications, and industry, it has become necessary to have simple inexpensive portable radiofrequency microwave field strength meters for health and safety surveys around operating equipment. T...
journal_title:Health physics
pub_type: 杂志文章
doi:10.1097/00004032-199702000-00018
更新日期:1997-02-01 00:00:00
abstract::The movement through the environment and the toxicity to plants of 99Tc have been studied. However, information is scanty on 99Tc toxicity to mammals even though this is the decisive criterion for assessing the consequences of releases of Tc. A critical tissue could be the thyroid because of its preferential accumulat...
journal_title:Health physics
pub_type: 杂志文章
doi:10.1097/00004032-198908000-00014
更新日期:1989-08-01 00:00:00