Abstract:
BACKGROUND:Treatment options for plantar fasciitis have resulted in varied patient outcomes. The aim of this study was to compare a novel treatment, cryopreserved human amniotic membrane (c-hAM), to a traditional treatment, corticosteroid. Our hypothesis was that c-hAM would be safe and comparable to corticosteroids for plantar fasciitis in regard to patient outcomes. METHODS:A randomized, controlled, double-blind, single-center pilot study was completed. Patients were randomized into one of 2 treatment groups: c-hAM or corticosteroid. Patients received an injection at their initial baseline visit with an option for a second injection at their first 6-week follow-up. Total follow-up was obtained for 12 weeks after the most recent injection. The primary outcome measurement was the Foot Health Status Questionnaire (FHSQ). The secondary outcome measurements were the Visual Analog Scale (VAS) and verbally reported percentage improvement. Data were analyzed between groups for the 2 different cohorts (1 injection versus 2 injections). Twenty-three patients had complete follow-up. Fourteen were randomized to receive corticosteroid and 9 were randomized to receive c-hAM. RESULTS:Three patients in each group received second injections. With the numbers available, the majority of outcome measurements showed no statistical difference between groups. The corticosteroid did, however, have greater FHSQ shoe fit improvement (P = .0244) at 6 weeks, FHSQ general health improvement (P = .0132) at 6 weeks, and verbally reported improvement (P = .041) at 12 weeks in the one-injection cohort. Cryopreserved hAM had greater FHSQ foot pain improvement (P = .0113) at 18 weeks in the 2-injection cohort. CONCLUSION:Cryopreserved hAM injection may be safe and comparable to corticosteroid injection for treatment of plantar fasciitis. This is a pilot study and requires further investigation. LEVEL OF EVIDENCE:Level I, prospective randomized trial.
journal_name
Foot Ankle Intjournal_title
Foot & ankle internationalauthors
Hanselman AE,Tidwell JE,Santrock RDdoi
10.1177/1071100714552824subject
Has Abstractpub_date
2015-02-01 00:00:00pages
151-8issue
2eissn
1071-1007issn
1944-7876pii
1071100714552824journal_volume
36pub_type
杂志文章,随机对照试验abstract:BACKGROUND:Microsurgical reconstruction has improved limb salvage in patients who because of many etiologies have soft-tissue loss from the lower extremities. Free-tissue transfer to the foot and ankle often interferes with postoperative function and footwear because of the bulk of a muscle flap. The foot and ankle oft...
journal_title:Foot & ankle international
pub_type: 杂志文章
doi:10.1177/107110070502600302
更新日期:2005-03-01 00:00:00
abstract::Measurements of the vertical component of ground reaction force (ORF) and dynamic center of pressure (COP) were recorded for five subjects with midfoot level amputations and six with Syme's ankle disarticulation amputations. All of the subjects underwent amputation surgery as a consequence of peripheral vascular disea...
journal_title:Foot & ankle international
pub_type: 杂志文章
doi:10.1177/107110079701801006
更新日期:1997-10-01 00:00:00
abstract:BACKGROUND:The superficial peroneal nerve (SPN) and its branches are at risk during surgical exposures. Our study aimed to demonstrate the distribution of the SPN on the dorsum of the foot to aid in surgical procedures close to this nerve. METHODS:The SPN was dissected in 30 cadaver lower limbs (13 male and two female...
journal_title:Foot & ankle international
pub_type: 杂志文章
doi:10.1177/107110070602700609
更新日期:2006-06-01 00:00:00
abstract:BACKGROUND:Joint-preserving, realignment surgical procedures have gained increasing popularity as treatment of asymmetric early- and mid-stage ankle osteoarthritis. The aim of the present study was to quantify bilateral gait biomechanics in patients who underwent ankle realignment surgery by supramalleolar osteotomies....
journal_title:Foot & ankle international
pub_type: 杂志文章
doi:10.1177/1071100715577371
更新日期:2015-08-01 00:00:00
abstract:BACKGROUND:Weight-bearing radiographs are a critical component of evaluating foot and ankle pathology. An underlying assumption is that patients are placing 50% of their body weight on the affected foot during image acquisition. The accuracy of weight bearing during radiographs is unknown and, presumably, variable, whi...
journal_title:Foot & ankle international
pub_type: 杂志文章
doi:10.1177/1071100717695361
更新日期:2017-06-01 00:00:00
abstract::A retrospective review was performed on industrial patients who sustained calcaneal fractures within the State of Idaho during the years 1992 to 1994, and these patients were insured by the Idaho State Insurance Fund. Of 48 calcaneal fractures that occurred during this period, 18 were non-displaced extra-articular fra...
journal_title:Foot & ankle international
pub_type: 杂志文章
doi:10.1177/107110070002101102
更新日期:2000-11-01 00:00:00
abstract:BACKGROUND:This study evaluated an acellular dermal matrix allograft augmentation for chronic mid-substance peroneous longus and brevis tendon tears. The hypothesis was that acellular dermal matrix allograft augmentation of chronic longitudinal mid-substance or complete tears of both peroneal tendons provides sufficien...
journal_title:Foot & ankle international
pub_type: 杂志文章
doi:10.3113/FAI.2010.0136
更新日期:2010-02-01 00:00:00
abstract:BACKGROUND:Highly comminuted pilon fractures, especially with a compromised soft tissue envelope, present a challenging treatment scenario. This study presents our results for patients managed with ankle fusion rather than ORIF. MATERIALS AND METHODS:Fourteen patients with ankle joint incongruence after non-reconstruc...
journal_title:Foot & ankle international
pub_type: 杂志文章
doi:10.3113/FAI.2008.0914
更新日期:2008-09-01 00:00:00
abstract::Contemporary methods of bone grafting osteochondral defects, in which the remaining overlying cartilage is relatively well preserved, have inherent problems. The bony defects are often saucer-shaped and the cylindrical graft may not fill the void, leaving areas of cartilage with no underlying scaffold and obviating ea...
journal_title:Foot & ankle international
pub_type: 杂志文章
doi:10.3113/FAI.2008.0616
更新日期:2008-06-01 00:00:00
abstract:BACKGROUND:Little information is available on the American Orthopaedic Foot and Ankle Society (AOFAS) outcome tool and its capacity to show changes and improvement in function of patients without a floor or ceiling effect. The purpose of the study was to compare results from the Musculoskeletal Functional Assessment (M...
journal_title:Foot & ankle international
pub_type: 杂志文章
doi:10.3113/FAI.2006.0788
更新日期:2007-07-01 00:00:00
abstract:BACKGROUND:Metastatic disease of the skeleton occurs in at least 20% to 30% of patients with malignancy, but metastasis to the foot and hand (acrometastasis) is extremely rare (0.007% to 0.3%). Metastases to the feet are even rarer and have been reported in half to one-third the rate for hand metastases. Failure to rec...
journal_title:Foot & ankle international
pub_type: 杂志文章,评审
doi:10.3113/FAI.2008.0699
更新日期:2008-07-01 00:00:00
abstract::In this study, 29 patients were hospitalized with a diabetic foot infection and were treated with piperacillin/tazobactam. Of these 23 patients who were evaluated for efficacy of treatment, 22 patients improved or were clinically cured. In seven patients (30%), there was persistence of one of the baseline pathogens. A...
journal_title:Foot & ankle international
pub_type: 杂志文章
doi:10.1177/107110079801900311
更新日期:1998-03-01 00:00:00
abstract::Sixty-one patients underwent a primary ankle lateral ligament reconstruction for chronic instability between 1989 and 1996. In addition to the ligament reconstruction, all patients had evaluation of the peroneal retinaculum, peroneal tendon inspection by routine opening of the tendon sheath, and ankle joint inspection...
journal_title:Foot & ankle international
pub_type: 杂志文章
doi:10.1177/107110070002101003
更新日期:2000-10-01 00:00:00
abstract::A case of tibiofibular synostosis stress fracture is reported with its clinical and radiographic appearance as well as treatment. ...
journal_title:Foot & ankle international
pub_type: 杂志文章
doi:10.1177/107110070402500711
更新日期:2004-07-01 00:00:00
abstract::The mobility and stability of the ankle joint have been extensively investigated, but many critical important issues still need to be elucidated. However, there seems to be a general agreement on several important observations. A more isometric pattern of rotation for the calcaneofibular and the tibiocalcaneal ligamen...
journal_title:Foot & ankle international
pub_type: 杂志文章,评审
doi:10.1177/107110070002100715
更新日期:2000-07-01 00:00:00
abstract::The capability for discrimination of vibratory stimuli of the sole of the foot was tested on 12 subjects (6 men, 6 women). Two vibratory stimuli (sinusoidal impulse: frequency, 200 Hz; amplitude, 0.1 mm; duration, 2 sec) were applied at different sites to the sole of the foot. Subjects were asked whether they detected...
journal_title:Foot & ankle international
pub_type: 杂志文章
doi:10.1177/107110079601701008
更新日期:1996-10-01 00:00:00
abstract:BACKGROUND:The structural importance of the spring ligament complex in arch stability has been described. Furthermore, the pathology of this complex is often noted in patients with posterior tibial tendon dysfunction. The purpose of this biomechanical study was to evaluate spring ligament repair alone versus augmentati...
journal_title:Foot & ankle international
pub_type: 杂志文章
doi:10.1177/1071100719828373
更新日期:2019-05-01 00:00:00
abstract:BACKGROUND:Isolated lateral calcaneocuboid joint instability rarely is described. Missed or delayed diagnosis resulting in inadequate treatment may lead to chronic instability, followed by sports inability and handicap in daily life. Besides arthrodesis, anatomic repair augmenting the elongated dorsal calcaneocuboid li...
journal_title:Foot & ankle international
pub_type: 杂志文章
doi:10.3113/FAI.2007.0202
更新日期:2007-02-01 00:00:00
abstract:BACKGROUND:There is a paucity of literature on the effect of calcaneal fractures on subtalar joint motion and patient satisfaction. The objective of this study was to determine the relationship between subtalar joint motion and outcome satisfaction in patients who had displaced intraarticular calcaneal fractures. The d...
journal_title:Foot & ankle international
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1177/107110070402500912
更新日期:2004-09-01 00:00:00
abstract:BACKGROUND:Procedures utilized to address the flatfoot in this study included medializing calcaneal osteotomy, posterior tibial tendon reconstruction with flexor digitorum longus tendon transfer, and in patients with more severe deformity, lateral column lengthening. We evaluated patients age 50 and less at the time of...
journal_title:Foot & ankle international
pub_type: 杂志文章
doi:10.3113/FAI.2008.1179
更新日期:2008-12-01 00:00:00
abstract:BACKGROUND:Bunionette deformity is characterized as head hypertrophy, lateral bowing, or splaying of the fifth metatarsal, or a combination of these deformities. Most previous studies have focused on the fourth and fifth metatarsals; few have analyzed the radiographic morphologic characteristics of the entire foot. The...
journal_title:Foot & ankle international
pub_type: 杂志文章
doi:10.1177/1071100715614923
更新日期:2016-03-01 00:00:00
abstract::We studied the validity and reliability of the Foot and Ankle Outcome Score (FAOS) when used to evaluate the outcome of 213 patients (mean age 40 years, 85 females) who underwent anatomical reconstruction of the lateral ankle ligaments with an average postoperative follow-up of 12 years (range, three to 24 years). The...
journal_title:Foot & ankle international
pub_type: 杂志文章
doi:10.1177/107110070102201004
更新日期:2001-10-01 00:00:00
abstract:BACKGROUND:Both the percutaneous technique with arthroscopic assistance, also known as arthroscopic Broström (AB), and the arthroscopic all-inside ligament repair (AI) are widely used to treat chronic lateral ankle instability. The aim of this study was to compare the clinical outcomes of these 2 arthroscopic stabilizi...
journal_title:Foot & ankle international
pub_type: 杂志文章
doi:10.1177/1071100720938672
更新日期:2020-11-01 00:00:00
abstract::The use of locking plate technology in foot and ankle surgery has increased over the last decade. Reported applications include fracture repair, deformity correction, and arthrodesis. There is limited evidence, however, to guide clinicians with regard to the appropriate and optimal use of this technology. This work ai...
journal_title:Foot & ankle international
pub_type: 杂志文章,评审
doi:10.1177/1071100714523274
更新日期:2014-05-01 00:00:00
abstract::This study examined stance phase foot kinematics, kinetics and electromyographic (EMG) activity of extrinsic muscles of 18 healthy males. Three-dimensional kinematic and kinetic data were obtained via video analysis of surface markers and a force plate. Ankle joint moments are described about orthogonal axes in a segm...
journal_title:Foot & ankle international
pub_type: 临床试验,杂志文章
doi:10.1177/107110070102200105
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND:The Krackow locking loop technique has been used for Achilles tendon repair with documented success in allowing early range of motion with stable fixation. Previous studies documented failure at the rupture site by knot failure. We propose a modification of the traditional Krackow technique where the knots o...
journal_title:Foot & ankle international
pub_type: 杂志文章
doi:10.3113/FAI-2009-0410
更新日期:2009-05-01 00:00:00
abstract:BACKGROUND:AES mobile-bearing total ankle replacement is evolved from the Buechel Pappas model. We report medium-term results of a prospective study with AES. MATERIALS AND METHODS:All patients who underwent AES TAR for ankle arthritis, by a single surgeon, from 2003 to 2006 were included, excluding neurologic disease...
journal_title:Foot & ankle international
pub_type: 杂志文章
doi:10.3113/FAI.2009.0964
更新日期:2009-10-01 00:00:00
abstract:BACKGROUND:The tendo Achilles (TA) is a tendon very susceptible to injury. Biomechanical methodologies for exploring tendon strain are limited, however, as they are typically performed in vitro or by indirectly measuring the displacement of reference markers. By using panoramic ultrasound, this study reports a novel ap...
journal_title:Foot & ankle international
pub_type: 杂志文章
doi:10.3113/FAI.2010.0905
更新日期:2010-10-01 00:00:00
abstract:BACKGROUND:Conventional bacterial cultures frequently fail to identify the dominant pathogen in polymicrobial foot infections, in which Staphylococcus aureus is the most common infecting pathogen. Previous work has shown that species-specific immunoassays may be able to identify the main pathogen in musculoskeletal inf...
journal_title:Foot & ankle international
pub_type: 杂志文章
doi:10.1177/1071100720965136
更新日期:2020-11-09 00:00:00
abstract:BACKGROUND:Studies using footprint-based estimates of arch height have indicated that obesity results in a lowered medial longitudinal arch in children. However, the potentially confounding effect of body composition on indirect measures of arch height, such as the arch index, has not been investigated. METHODS:This s...
journal_title:Foot & ankle international
pub_type: 杂志文章
doi:10.1177/107110070402500811
更新日期:2004-08-01 00:00:00