Abstract：
:In this study, we serologically and pathologically examined the clinical significance of fibroblast growth factor (FGF) expression in patients with colorectal cancer. Serum basic FGF (bFGF) levels in 92 surgical colorectal cancer patients and 31 controls were measured, and the relationship between those levels and clinicopathological factors were examined. Immunohistochemical study was also conducted on specimens from 51 cancer patients, and the association between bFGF staining and serum levels were investigated. An examination of clinicopathological factors revealed significant differences in bFGF levels between stage 0-IIIb and stage IV cancers (P = 0.013). Lymphatic invasion was one factor that differed significantly. Patients with a tumor 30 mm or smaller had a bFGF level of 7.65 ± 1.11 pg/ml while patients with a tumor 31 mm or larger had a bFGF level of 8.53 ± 3.22 pg/ml; significant differences in these bFGF levels were noted (P < 0.05). Patients with a tumor that had no lymphatic invasion (ly0) had a bFGF level of 7.25 ± 0.66 pg/ml, those with a tumor that had minimal lymphatic invasion (ly1) had a bFGF level of 7.99 ± 1.68 pg/ml, and those with a tumor that had moderate lymphatic invasion (ly2) had a bFGF level of 9.17 ± 4.23 pg/ml. bFGF levels differed significantly for tumors with no/minimal lymphatic invasion (ly0-ly1) and those with moderate lymphatic invasion (ly2) (P < 0.0001). Serological examination of bFGF levels during the proliferation of colorectal cancer revealed that moderate lymphatic invasion can be readily distinguished.
journal_name
Int Surgjournal_title
International surgeryauthors
Jibiki N,Saito N,Kameoka S,Kobayashi Mdoi
10.9738/INTSURG-D-14-00044.1subject
Has Abstractpub_date
2014-09-01 00:00:00pages
493-9issue
5eissn
0020-8868issn
2520-2456journal_volume
99pub_type
杂志文章abstract：:The effect on cellular immunity of the administration of the non-specific immunopotentiator BCG and/or a streptococcal agent was studied in 90 non-cancer bearing Wistar rats under different nutritional support. The number of immunocompetent cells and the non-specific function of the immunocompetent cells significantly...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1984-01-01 00:00:00
abstract：:The activities of cathepsin B, D and G, and their distribution in the walls of normal aorta and those of aneurysms of abdominal aorta were studied. The immunohistochemical reaction for these cathepsins was positive in the aneurysm wall both in the cells and in the extracellular matrix. It was more apparent than in nor...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1997-10-01 00:00:00
abstract：:The purpose of this study was to evaluate the success and morbidity of percutaneous nephrolithotomy (PCNL) performed through the 11th and 10th intercostal space. Between March 2005 and February 2012, 612 patients underwent PCNL, 243 of whom had a supracostal access. The interspace between the 11th and 12th rib was use...
journal_title：International surgery
pub_type： 杂志文章
doi：10.9738/INTSURG-D-13-00167.1
更新日期：2014-11-01 00:00:00
abstract：:This paper reports an unusual case of orthopedic trauma in a 29-year-old man who experienced concomitant bilateral anterior shoulder fracture dislocation with associated brachial plexus and axillary artery injury. We also highlight the mechanism underlying this rare workplace injury related to use of a forklift. ...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：2007-03-01 00:00:00
abstract：:Two rare cases of carcinosarcoma of the esophagus are presented. In the first case the decision to operate was based on an initial diagnosis of leiomyosarcoma made by endoscopic biopsy. In the second, a diagnosis of carcinosarcoma was also obtained by endoscopic biopsy. The pathology is commented on. The authors discu...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1980-09-01 00:00:00
abstract：:Bronchobiliary fistula (BBF) is a rare condition which occurs most commonly as a complication of hydatid cyst liver disease. The following report describes a patient who presented with biliptysis 6 months following decortication of an empyema that had occurred following partial hepatectomy of a colon cancer metastasis...
journal_title：International surgery
pub_type： 杂志文章
doi：10.9738/INTSURG-D-13-00095.1
更新日期：2014-07-01 00:00:00
abstract：PURPOSE:The infrequency of right-sided colonic diverticulitis prompted this presentation of our experiences, with emphasis on the diagnostic aspects. PATIENTS AND METHODS:Charts and documentation regarding 20 patients who underwent surgery for diverticulitis of the caecum and/or ascending colon over 22 years were revi...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：2000-01-01 00:00:00
abstract：:Synchronous primary anorectal melanoma and colorectal adenocarcinoma is extremely rare, with only 5 cases reported in the literature. Here, a case is reported and the currently available literature is summarized. A 72-year-old white male presented with changes in his bowel habits and unintentional weight loss. Colonos...
journal_title：International surgery
pub_type： 杂志文章,评审
doi：10.9738/INTSURG-D-14-00243
更新日期：2015-05-01 00:00:00
abstract：:We made clinical trials of en bloc extended radical mastectomy (EXT) of a new type in 118 patients from 1980 through 1985. A variety of conventional radical mastectomies (RDL) were also performed in 105 patients from 1973 through 1985. A multivariate analysis was performed of the results to compare EXT and RDL. The re...
journal_title：International surgery
pub_type： 临床试验,杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：:The purpose of this study was to investigate prognostic significance of Dopamine and cAMP-Regulated neuronal Phosphoprotein 32 (DARPP-32) expression in primary colorectal cancer. The study material consisted of clinical and histopathological data of 100 patients operated for colorectal cancer between 1994 and 1997. Fo...
journal_title：International surgery
pub_type： 杂志文章
doi：10.9738/INTSURG-D-14-00022.1
更新日期：2015-02-01 00:00:00
abstract：:One hundred cases of malignant tumors of the larynx, pharynx, oral cavity, nose and paranasal sinuses were studied. The hypopharynx was the most frequent site and the most common type of tumor was squamous cell carcinoma. Lymph nodes were palpable in 59% of cases, of which 72.8% showed histological evidence of metasta...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1977-06-01 00:00:00
abstract：:A consecutive series of 385 patients with intussusception treated between January 1, 1982 and December 31, 1987 was analysed. Male patients predominated over female by a ratio of 2.2:1. Seventy nine per cent of patients were under 12 months of age. There was no seasonal variation in the incidence of intussusception. R...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1989-04-01 00:00:00
abstract：:Ten cases of renal hypertension with uncommon causes were presented and unusual problems in their diagnosis and surgical management were discussed. These causes included segmental stenosis involving aberrant renal artery, renal artery stenosis in association with renal arteriovenous fistula, postoperative renal hypert...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1976-03-01 00:00:00
abstract：:The effectiveness of low-molecular weight heparin CY 216 in the prophylaxis of fatal pulmonary embolism in patients undergoing general surgery was assessed in a multicentre, double-blind, randomized, clinical trial against placebo. A total of 4,498 patients aged over 40 undergoing general surgery were enrolled in the ...
journal_title：International surgery
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：
更新日期：1989-10-01 00:00:00
abstract：:The clinicopathological features of 84 muscularis propria (mp) gastric cancers, defined as gastric cancer invading the muscularis propria of the stomach, were reviewed retrospectively, and compared with 267 early gastric cancers (m/sm cancer) and 333 gastric cancers invading beyond the subserosal layer (ss-si cancer)....
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1999-01-01 00:00:00
abstract：:About 5% of patients with chronic liver disease develop massive refractory ascites. These patients cease to respond to diuretic therapy and may develop prerenal azotemia. There is a small but definite role for the peritoneo-venous shunt in these patients. In our study of 36 patients, managed with locally made, single-...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：2004-04-01 00:00:00
abstract：:In 17 years we have performed 6,505 neurosurgical procedures in the neurosurgical unit of the Salisbury Hospital Group. Only 62% were performed on Africanpatients and 38% on European patients, despite the fact that the African population exceeds the European population by 20 times. This is partly due to the tolerance ...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1975-05-01 00:00:00
abstract：:Surgical site infection (SSI) is disastrous in orthopedic practice as it is difficult to rid the bone and joint of the infection. This study was aimed to assess the prevalence of SSI in orthopedic practice and to identify risk factors associated with surgical site infections. All patients admitted to the orthopedic ma...
journal_title：International surgery
pub_type： 杂志文章
doi：10.9738/INTSURG-D-13-00251.1
更新日期：2014-05-01 00:00:00
abstract：:Pancreaticoduodenectomy is considered the standard operation for periampullary tumors. Despite major advances in pancreatic surgery, pancreatic fistula is still an important cause of morbidity and mortality after pancreaticoduodenectomy. Meticulous surgical technique and proper reconstruction of the pancreas are essen...
journal_title：International surgery
pub_type： 杂志文章
doi：10.9738/INTSURG-D-14-00095.1
更新日期：2015-02-01 00:00:00
abstract：:A retrospective study of 46 patients who received bupivacaine local injections after hemorrhoidectomy were compared to a matching group of 46 patients of similar age and sex distribution who underwent the same operation. Pain medications requirement on the same day of operation and on subsequent days were measured and...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1998-01-01 00:00:00
abstract：:Between 1965 and 1979, 934 patients underwent 1,057 operations for extracranial carotid stenosis at this institute, and over a recent 30-month period 463 patients underwent 511 operations of this type. This number is equal to the total of operations performed during the years 1965-1976. The increase in the frequency o...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1981-07-01 00:00:00
abstract：:Experimentally produced angulatory deformities of rat tibia with and without physeal injury were observed at two to three-week intervals for an eight-week period by x-ray studies, in order to estimate the spontaneous correctability of tibial deformity in growing rats. The results obtained were as follows: 1) In the re...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1980-07-01 00:00:00
abstract：:We report the case of a 57-year-old woman with Budd-Chiari syndrome, hepatocellular carcinoma (HCC), and intrahepatic cholangiocarcinoma (ICC). She underwent partial hepatectomy for HCC in April 2000. After surgery, alpha-fetoprotein (AFP) and protein induced by vitamin K absence II (PIVKA-II) returned to normal level...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：2005-04-01 00:00:00
abstract：:A case of acinar cell carcinoma of the pancreas with elevated serum alpha-fetoprotein (AFP) is presented. The diagnosis was reached using histopathological techniques. AFP was positive in the tumor specimen, immunohistochemically. Serum AFP had fallen temporarily after surgery and chemotherapy. The patient survived 6....
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1984-10-01 00:00:00
abstract：:Cases with concurrent pheochromocytoma and renal artery stenosis, two "surgically curable" hypertensive disorders, are rare. The stenosis is generally secondary to direct compression or stretching of the renal artery by the tumor. Five such cases are reported. Sometimes the tumor and the renal artery stenosis occur in...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1985-04-01 00:00:00
abstract：:No topic in the field of vascular surgery evokes more controversy than the management of the patient with asymptomatic carotid artery stenosis. The fact remains, however, that patients can and do develop stroke without any antecedent TIA, and there is no definite and predictable way to identify the stroke-prone group....
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1984-07-01 00:00:00
abstract：:In a group of 82 women with congenital or acquired uterine malformation (such as intrauterine adhesions or uterus myomatosus), cerclage was successfully performed according to the McDonald method. The percentage of term deliveries increased from 29.8% to 69.2% and the percentage of spontaneous abortions decreased from...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1977-04-01 00:00:00
abstract：:Obesity is an additional risk factor in surgical patients. The mortality rate in obese patients is high (3.6% in my series) and the morbidity is much higher. These patients may be prediabetic, diabetic, hypertensive or atherosclerotic and they are liable to develop postoperative coronary thromboses and chest complicat...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1985-04-01 00:00:00
abstract：:A gallstone ileus is an unusual form of bowel obstruction. Colonic gallstone ileus is rare, difficult to diagnose, and still has a high mortality rate. We present a case of biliary ileus caused by an impacted gallstone, causing necrosis and perforation of the rectosigmoid junction. A Hartmann's procedure was performed...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：2009-01-01 00:00:00
abstract：:Incidence of cholelithiasis in the teaching hospital population of India has been reported. The study suggests that North Indians are more prone to cholelithiasis than South Indians. Apparently this variation is related to dietary and geographical factors. ...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1977-03-01 00:00:00
