How accurate is sperm morphology as an indicator of sperm function?

Abstract:

:Sperm morphology has been consistently correlated with fertilisation success or failure. The clinical relevance of the percentage normal spermatozoa has been a widely discussed topic amongst infertility specialists and scientists. This study aimed to evaluate the role of sperm morphology as an indicator of additional sperm functions among 114 andrology referrals. The sperm functions that were investigated included chromatin packaging quality (CMA3 test (n = 109), zona-induced acrosome reaction (ZIAR test; n = 36), hemizona assay (HZI; n = 36) and progressive motility (n = 47). Chromatin packaging quality had a negative and significant (P = 0.0001, r = -0.74) correlation with the percentage normal spermatozoa, while progressive motility had a significant and positive correlation (P = 0.0001, 0.59). Accurate sperm morphology scoring as described by the WHO 2010 manual can therefore be used as an indicator of specific sperm functions.

journal_name

Andrologia

journal_title

Andrologia

authors

Franken DR

doi

10.1111/and.12324

subject

Has Abstract

pub_date

2015-08-01 00:00:00

pages

720-3

issue

6

eissn

0303-4569

issn

1439-0272

journal_volume

47

pub_type

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